Page last updated: 2024-10-27

fluorouracil and Melanoma, Amelanotic

fluorouracil has been researched along with Melanoma, Amelanotic in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Melanoma, Amelanotic: An unpigmented malignant melanoma. It is an anaplastic melanoma consisting of cells derived from melanoblasts but not forming melanin. (Dorland, 27th ed; Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"Amelanotic lentigo maligna melanoma (ALMM) is an infrequent presentation of lentigo maligna melanoma, less than thirty cases having been reported to date."2.40Amelanotic lentigo maligna melanoma: report of a case and review of the literature. ( de Moragas, JM; Puig, L; Rocamora, V; RomanĂ­, J, 1999)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al-Haseni, A1
Chitgopeker, P1
Ho, JD1
Goldberg, LJ1
Sahni, D1
Rocamora, V1
Puig, L1
RomanĂ­, J1
de Moragas, JM1

Reviews

1 review available for fluorouracil and Melanoma, Amelanotic

ArticleYear
Amelanotic lentigo maligna melanoma: report of a case and review of the literature.
    Cutis, 1999, Volume: 64, Issue:1

    Topics: Aged; Antineoplastic Agents; Combined Modality Therapy; Cryotherapy; Dicarboxylic Acids; Female; Flu

1999

Other Studies

1 other study available for fluorouracil and Melanoma, Amelanotic

ArticleYear
Amelanotic melanoma arising within a lesion of disseminated superficial actinic porokeratosis: An unusual presentation leading to a novel therapeutic approach.
    Dermatologic therapy, 2018, Volume: 31, Issue:1

    Topics: Administration, Cutaneous; Aged; Antimetabolites, Antineoplastic; Bandages; Biopsy; Cell Transformat

2018