fluorouracil has been researched along with Mediastinal Neoplasms in 20 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Mediastinal Neoplasms: Tumors or cancer of the MEDIASTINUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors retrospectively evaluated 3 patients with progressive, metastatic neuroendocrine tumors of the thymus who were treated with a combination of capecitabine and temozolomide." | 7.79 | Treatment of metastatic neuroendocrine tumors of the thymus with capecitabine and temozolomide: a case series. ( Centeno, B; Kvols, L; Morse, B; Saranga-Perry, V; Strosberg, J, 2013) |
| "The authors retrospectively evaluated 3 patients with progressive, metastatic neuroendocrine tumors of the thymus who were treated with a combination of capecitabine and temozolomide." | 3.79 | Treatment of metastatic neuroendocrine tumors of the thymus with capecitabine and temozolomide: a case series. ( Centeno, B; Kvols, L; Morse, B; Saranga-Perry, V; Strosberg, J, 2013) |
| "A carcinostatic substance (5-fluorouracil) was instilled into the mediastinal lymph nodes, the pleural cavity or the internal thoracic artery by continuous perfusion before operation on patients with bronchial carcinoma." | 3.65 | [Continuous local application of cytostatics for bronchial carcinoma and mediastinal lymph node metastasisization (author's transl)]. ( Inoguchi, T; Kita, T; Kuwano, K; Yamasaki, I; Yazuka, K, 1976) |
| "Treatment of both Hodgkin's disease (HD) and high-grade non-Hodgkin's lymphoma (HG-NHL) with bulky presentation at diagnosis frequently results in residual masses detected radiologically." | 2.68 | Monitoring bulky mediastinal disease with gallium-67, CT-scan and magnetic resonance imaging in Hodgkin's disease and high-grade non-Hodgkin's lymphoma. ( Babini, L; Barbieri, E; Battista, G; Bendandi, M; Canini, R; Fanti, S; Frezza, G; Gherlinzoni, F; Gozzetti, A; Merla, E; Monetti, N; Pisi, P; Rimondi, MR; Tura, S; Zinzani, PL; Zompatori, M, 1996) |
| "A total of 49 patients with metastatic renal cell cancer underwent recombinant interferon-alpha 2a therapy combined with chemotherapy." | 2.67 | Phase II study of interferon-alpha and chemotherapy (5-fluorouracil and mitomycin C) in metastatic renal cell cancer. ( Amato, R; Dexeus, FH; Fitz, K; Kilbourn, R; Logothetis, CJ; Sella, A; Wallace, S, 1992) |
| " 5-FU was administered intracavitary in all patients combined with systemic chemotherapy." | 1.28 | Intracavitary 5-fluoro-uracil (5-FU) in combination with systemic chemotherapy. ( Boaziz, C; Breau, JL; Delanian, S; Israel, L; Morere, JF, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (45.00) | 18.7374 |
| 1990's | 8 (40.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hori, A | 1 |
| Ohira, R | 1 |
| Nakamura, T | 1 |
| Kimura, Y | 1 |
| Ueda, S | 1 |
| Torii, M | 1 |
| Kennoki, N | 1 |
| Hori, S | 1 |
| Saranga-Perry, V | 1 |
| Morse, B | 1 |
| Centeno, B | 1 |
| Kvols, L | 1 |
| Strosberg, J | 1 |
| KOOP, CE | 1 |
| KARNOFSKY, DA | 1 |
| Zhou, ZT | 1 |
| Wang, JW | 1 |
| Yang, L | 1 |
| Wang, J | 1 |
| Zhang, W | 1 |
| Mazza, P | 1 |
| Zinzani, PL | 3 |
| Martelli, M | 2 |
| Fiacchini, M | 1 |
| Bocchia, M | 1 |
| Pileri, S | 1 |
| Falini, B | 1 |
| Martelli, MF | 1 |
| Amadori, S | 1 |
| Papa, G | 1 |
| Zompatori, M | 1 |
| Bendandi, M | 2 |
| Battista, G | 1 |
| Fanti, S | 1 |
| Barbieri, E | 1 |
| Gherlinzoni, F | 2 |
| Rimondi, MR | 1 |
| Frezza, G | 2 |
| Pisi, P | 1 |
| Merla, E | 2 |
| Gozzetti, A | 1 |
| Canini, R | 1 |
| Monetti, N | 1 |
| Babini, L | 2 |
| Tura, S | 2 |
| Salvucci, M | 1 |
| Magagnoli, M | 1 |
| Matsubara, T | 1 |
| Ueda, M | 1 |
| Nagao, N | 1 |
| Takahashi, T | 1 |
| Nakajima, T | 1 |
| Nishi, M | 1 |
| Martelli, MP | 1 |
| Pescarmona, E | 1 |
| De Sanctis, V | 1 |
| Donato, V | 1 |
| Palombi, F | 1 |
| Todisco, E | 1 |
| Rendina, EA | 1 |
| Pau, FM | 1 |
| Mandelli, F | 1 |
| Samuels, ML | 1 |
| Holoye, PY | 1 |
| Johnson, DE | 1 |
| Inoguchi, T | 2 |
| Yamasaki, I | 1 |
| Yazuka, K | 1 |
| Kita, T | 1 |
| Kuwano, K | 2 |
| Rieche, K | 1 |
| Matthes, ML | 1 |
| Sella, A | 1 |
| Logothetis, CJ | 1 |
| Fitz, K | 1 |
| Dexeus, FH | 1 |
| Amato, R | 1 |
| Kilbourn, R | 1 |
| Wallace, S | 1 |
| Todeschini, G | 1 |
| Ambrosetti, A | 1 |
| Meneghini, V | 1 |
| Pizzolo, G | 1 |
| Menestrina, F | 1 |
| Chilosi, M | 1 |
| Benedetti, F | 1 |
| Veneri, D | 1 |
| Cetto, GL | 1 |
| Perona, G | 1 |
| Dunphy, FR | 1 |
| Spitzer, G | 1 |
| Morere, JF | 1 |
| Delanian, S | 1 |
| Boaziz, C | 1 |
| Breau, JL | 1 |
| Israel, L | 1 |
| Sasatomi, N | 1 |
| Kumaoka, S | 1 |
| Takeda, H | 1 |
| Lokich, JJ | 1 |
| Sickles, EA | 1 |
| Belliveau, RE | 1 |
| Wiernik, PH | 1 |
5 trials available for fluorouracil and Mediastinal Neoplasms
| Article | Year |
|---|---|
MACOP-B vs F-MACHOP regimen in the treatment of high-grade non-Hodgkin's lymphomas.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Diseases; Cyclophospha | 1995 |
Monitoring bulky mediastinal disease with gallium-67, CT-scan and magnetic resonance imaging in Hodgkin's disease and high-grade non-Hodgkin's lymphoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Ther | 1996 |
Primary Mediastinal B-cell lymphoma with sclerosis: clinical and therapeutic evaluation of 22 patients.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Therapy; Cycloph | 1996 |
MACOP-B and involved field radiation therapy is an effective therapy for primary mediastinal large B-cell lymphoma with sclerosis.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Combined Modality Ther | 1998 |
Phase II study of interferon-alpha and chemotherapy (5-fluorouracil and mitomycin C) in metastatic renal cell cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Combined Modality Therapy; Dr | 1992 |
15 other studies available for fluorouracil and Mediastinal Neoplasms
| Article | Year |
|---|---|
Transarterial chemoembolization for pulmonary or mediastinal metastases from hepatocellular carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chemoemboliz | 2020 |
Treatment of metastatic neuroendocrine tumors of the thymus with capecitabine and temozolomide: a case series.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Dacarbazine; Deoxycytidine; Flu | 2013 |
CURRENT MANAGEMENT OF NEPHROBLASTOMA AND NEUROBLASTOMA.
Topics: Antineoplastic Agents; Child; Dactinomycin; Fluorouracil; Infant; Infant, Newborn; Kidney Neoplasms; | 1964 |
NONSURGICAL TREATMENT OF PULMONARY CANCER.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agen | 1964 |
[Primary germ cell tumor in the mediastinum-report of 47 cases].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Cisplatin; Combined Modali | 2006 |
Surgical treatment for carcinoma of the thoracic esophagus with major involvement in the neck or upper mediastinum.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Esophageal Neo | 1998 |
Bleomycin combination chemotherapy in the management of testicular neoplasia.
Topics: Abdominal Neoplasms; Adult; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Dysgerminoma; Fl | 1975 |
[Continuous local application of cytostatics for bronchial carcinoma and mediastinal lymph node metastasisization (author's transl)].
Topics: Adenocarcinoma; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regi | 1976 |
[Clinical evaluation of Ftorafur (author's transl)].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Drug | 1975 |
Mediastinal large-B-cell lymphoma with sclerosis: a clinical study of 21 patients.
Topics: Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bleom | 1990 |
Long-term complete remission of stage IV breast cancer after high-dose chemotherapy and autologous bone marrow transplantation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms | 1990 |
Intracavitary 5-fluoro-uracil (5-FU) in combination with systemic chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheters, Indwelling; Combined Modalit | 1989 |
[Topical administration of carcinostatics to mediastinal lymph node lesion metastasized lung cancer--an adjuvant therapy in surgery of lung cancer].
Topics: Animals; Dogs; Fluorouracil; Gold Colloid, Radioactive; Humans; Injections; Injections, Intra-Arteri | 1972 |
The management of malignant pericardial effusions.
Topics: Angiography; Cardiac Tamponade; Fluorouracil; Gold; Heart Neoplasms; Humans; Lung; Mechlorethamine; | 1973 |
Primary mediastinal choriocarcinoma in the male.
Topics: Adult; Choriocarcinoma; Cyclophosphamide; Cytodiagnosis; Drug Therapy, Combination; Fluorouracil; Hu | 1974 |