Page last updated: 2024-10-27

fluorouracil and Mediastinal Diseases

fluorouracil has been researched along with Mediastinal Diseases in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Mediastinal Diseases: Disorders of the mediastinum, general or unspecified.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ohtsu, A1
Yoshida, S1
Boku, N1
Fujii, T1
Oda, Y1
Miyata, Y1
Koba, I1
Muro, K1
Ohnaka, O1
Shimizu, W1

Other Studies

1 other study available for fluorouracil and Mediastinal Diseases

ArticleYear
Small cell carcinoma of the esophagus with an esophago-mediastinal fistula successfully treated by chemoradiation therapy and intubation: a case report.
    Japanese journal of clinical oncology, 1993, Volume: 23, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cobalt Radioisotop

1993