fluorouracil has been researched along with Mediastinal Diseases in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Mediastinal Diseases: Disorders of the mediastinum, general or unspecified.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohtsu, A | 1 |
| Yoshida, S | 1 |
| Boku, N | 1 |
| Fujii, T | 1 |
| Oda, Y | 1 |
| Miyata, Y | 1 |
| Koba, I | 1 |
| Muro, K | 1 |
| Ohnaka, O | 1 |
| Shimizu, W | 1 |
1 other study available for fluorouracil and Mediastinal Diseases
| Article | Year |
|---|---|
Small cell carcinoma of the esophagus with an esophago-mediastinal fistula successfully treated by chemoradiation therapy and intubation: a case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cobalt Radioisotop | 1993 |