Compounds > fluorouracil
Page last updated: 2024-10-27

fluorouracil and Maxillary Neoplasms

fluorouracil has been researched along with Maxillary Neoplasms in 45 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Maxillary Neoplasms: Cancer or tumors of the MAXILLA or upper jaw.

Research Excerpts

ExcerptRelevanceReference
"Over forty percent patients with squamous cell carcinoma showed moderate chemosensitivity to VM-26, CDDP and E-ADM, and over forty percent cases with adenoid carcinoma showed moderate chemosensitivity to Vm-26, Taxol and E-ADM."1.31[Chemosensitivity testing of oral and maxillofacial cancer with biopsy specimens]. ( Chen, W; Guo, W; Lin, L; Xu, Q; Zhou, X, 2002)
"Treatment of the head and neck cancer has surprisingly developed in the last decade."1.27[Multidisciplinary treatment of the head and neck cancer--FAR therapy and its modification and application]. ( Komiyama, S; Kudo, S; Kuwano, N; Yanagita, T, 1986)
"As far as squamous cell carcinoma is concerned, the post-therapeutic courses of our combination therapy have been satisfactory."1.27Analysis of the long-term results of our combination therapy for maxillary cancer, with particular reference to treatment of T4 and N1-3 maxillary cancer. ( Hanazawa, S; Konno, A; Okamoto, Y; Togawa, K, 1985)
"In the total 70 cases including those of undifferentiated carcinoma and adenocarcinoma, the 3-year and 5-year actual survival rates were 75."1.26Analysis of the results of our combined therapy for maxillary cancer. ( Inoue, S; Konno, A; Togawa, K, 1980)
" Treatment was combined with cobalt 60 irradiation at 4,000 rads (200 rads X 20 doses over a one month period) and concurrent arterial infusion of 5-fluorouracil (5-FU) with a total dosage of 5,000 mg (250 mg X 20 doses)."1.26Use of phytohemagglutinin in the treatment of maxillary cancer. ( Okuda, M; Sakaguchi, K; Takahashi, M; Tomiyama, S, 1980)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199036 (80.00)18.7374
1990's4 (8.89)18.2507
2000's4 (8.89)29.6817
2010's1 (2.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maebayashi, T1
Ishibashi, N1
Aizawa, T1
Sakaguchi, M1
Ikeda, A1
Hirai, R1
Furusaka, T1
Homma, T1
Khasanov, AI1
Chen, W1
Zhou, X1
Xu, Q1
Guo, W1
Lin, L1
BAKER, RR1
GAERTNER, RA1
Iguchi, H1
Kusuki, M1
Nakamura, A1
Nishiura, H1
Kanazawa, A1
Takayama, M1
Sunami, K1
Yamane, H1
Inuyama, Y4
Fujii, M3
Tnaka, J1
Takaoka, T3
Hosoda, H3
Kohno, N3
Konno, A2
Togawa, K2
Inoue, S1
Yoneda, T2
Ogawa, T2
Sakuda, M2
Teshima, T1
Tanaka, Y3
Nishiyama, K1
Ikeda, H1
Masaki, N1
Shigematsu, Y2
Nakamura, M1
Fuchihata, H2
Hsieh, T1
Nakashima, T2
Matsumura, Y1
Nomura, Y1
Komiyama, S4
Makishima, K1
Hiroto, I2
Okuda, M1
Sakaguchi, K1
Tomiyama, S1
Takahashi, M3
Sato, S1
Kohno, K1
Hidaka, K1
Hisatsugu, T1
Kuwano, M1
Cutilli, T1
Papola, F1
Corbacelli, A1
Masuda, M1
Matsui, K1
Inokuchi, A1
Kuraoka, A1
Ijiri, R1
Onuma, K1
Ikeda, M1
Kato, K1
Toyoda, Y1
Nagashima, Y1
Ito, Y1
Abiko, Y1
Price, LA1
Hill, BT1
Calvert, AH1
Shaw, HJ1
Hughes, KB1
Esser, E1
Kroh, HD1
Schumann, J1
Wannenmacher, M1
Sokolova, II1
Demidov, VP2
Stiop, LD2
Gracheva, ZA1
Korotkikh, NG1
Volkova, MA1
Ol'shanskii, VO1
Bornovolokova, GA1
Sakai, S3
Nakajima, A2
Ikehata, S1
Ozaki, M2
Ikeda, Y1
Takahashi, H2
Tanaka, J2
Kubo, T1
Mori, N1
Itoh, M1
Miyaguchi, M1
Kitaoku, S1
Sakata, Y1
Yanagita, T1
Kudo, S1
Kuwano, N1
Okamoto, Y1
Hanazawa, S1
Mayer, M1
Colon, J1
Bassilios, MI1
Ramm, C1
Jarmolych, J1
Goffin, FB1
Hirano, M1
Mitsuhashi, S1
Ichikawa, A1
Okada, M1
Ikeda, K1
Yoshida, J1
Glupe, J1
Kraus, H1
Wannenmacher, E1
Kashiwado, S1
Sawaki, S1
Satake, K1
Matsui, M1
Takayama, I1
Ando, Y1
Katsumi, Y2
Shozu, R1
Takeyama, I1
Ando, K1
Ozu, R1
Kuroda, Y1
Ota, F1
Monju, T1
Egawa, S1
Nitze, HR1
Rosemann, G1
Matsukawa, J1
Miura, T1
Ishida, M1
Hatano, S1
Morita, M1
Sato, Y1
Watanabe, N1
Jesse, RH1
Goepfert, H1
Lindberg, RD1
Johnson, RH1

Reviews

1 review available for fluorouracil and Maxillary Neoplasms

ArticleYear
Effectiveness of chemoradiotherapy for radiation-induced bilateral external auditory canal cancer: A case report and literature review.
    Head & neck, 2019, Volume: 41, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cetuximab; Chemoradi

2019

Trials

1 trial available for fluorouracil and Maxillary Neoplasms

ArticleYear
[Trial and results of improved radiotherapy for cancer. 5. Radiotherapy with simultaneous administration of radio-sensitizing agents. Controlled trial at the Osaka University].
    Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:12

    Topics: Clinical Trials as Topic; Cycloheptanes; Cyclohexanols; Ethylamines; Fluorouracil; Humans; Imidazole

1972

Other Studies

43 other studies available for fluorouracil and Maxillary Neoplasms

ArticleYear
[Influence of chemotherapy regimen on antioxidant level in patients with locally-advanced tumors of the maxilla, nasal and paranasal sinuses].
    Voprosy onkologii, 2009, Volume: 55, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Chemotherapy,

2009
[Chemosensitivity testing of oral and maxillofacial cancer with biopsy specimens].
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2002, Volume: 37, Issue:6

    Topics: Antineoplastic Agents; Biopsy; Carcinoma, Squamous Cell; Cell Division; Cisplatin; Dose-Response Rel

2002
REGIONAL ARTERIAL INFUSION OF ANTIMETABOLITES. AN ANALYSIS OF THE RESULTS OBTAINED IN 33 PATIENTS WITH MALIGNANT TUMORS OF THE HEAD AND NECK.
    The Journal of surgical research, 1965, Volume: 5

    Topics: Antimetabolites; Carcinoma, Squamous Cell; Chemotherapy, Cancer, Regional Perfusion; Fluorouracil; H

1965
Concurrent chemoradiotherapy with pirarubicin and 5-fluorouracil for resectable oral and maxillary carcinoma.
    Acta oto-laryngologica. Supplementum, 2004, Issue:554

    Topics: Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Combined Mo

2004
[Cancer of the maxillary antrum--a new multidisciplinary treatment containing neo-adjuvant chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Combined Modality Therap

1984
Analysis of the results of our combined therapy for maxillary cancer.
    Acta oto-laryngologica. Supplementum, 1980, Volume: 372

    Topics: Adenocarcinoma; Adult; Age Factors; Aged; Antineoplastic Agents; Carcinoma; Carcinoma, Squamous Cell

1980
[Conversion of 1-(2-tetrahydrofuryl-5-fluorouracil (FT-207) into 5-fluorouracil (5-FU) by human maxillary cancer cells (OKK) in culture].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:4 Pt 2

    Topics: Cells, Cultured; Fluorouracil; Humans; Maxillary Neoplasms; Tegafur

1983
[Results of multidisciplinary treatment for squamous cell carcinoma of the maxillary antrum].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1984, Nov-25, Volume: 44, Issue:11

    Topics: Adult; Aged; Brachytherapy; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; Fluorouraci

1984
Treatment of maxillary cancer with three-combined method.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1980, Volume: 79, Issue:2

    Topics: Adult; Aged; Female; Fluorouracil; Humans; Male; Maxillary Neoplasms; Middle Aged; Neoplasm Recurren

1980
[Antitumor effect of UFT against malignant tumors of maxillary sinus--clinical and biochemical study].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1982, Volume: 9, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Fluorourac

1982
Use of phytohemagglutinin in the treatment of maxillary cancer.
    Archives of oto-rhino-laryngology, 1980, Volume: 228, Issue:2

    Topics: Aged; Carcinoma, Squamous Cell; Drug Therapy, Combination; Female; Fluorouracil; Humans; Infusions,

1980
Differentially potentiating effects by dipyridamole on cytotoxicity of 5-fluorouracil against three human maxillary cancer cell lines derived from a single tumor.
    Anti-cancer drug design, 1993, Volume: 8, Issue:4

    Topics: Cell Survival; Dipyridamole; Drug Synergism; Fluorodeoxyuridylate; Fluorouracil; Humans; Maxillary N

1993
p53 overexpression and mutation, chemoresistance and patient survival in oral and maxillofacial squamous cell carcinoma.
    Journal of chemotherapy (Florence, Italy), 1997, Volume: 9, Issue:2

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Sq

1997
Induction of apoptosis in maxillary sinus cancer cells by 5-fluorouracil, vitamin A and radiation (FAR) therapy.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 1999, Volume: 256 Suppl 1

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor;

1999
Pigmented intraosseous odontogenic carcinoma of the maxilla: a pediatric case report and differential diagnosis.
    Human pathology, 2001, Volume: 32, Issue:8

    Topics: Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma; Ch

2001
Kinetically-based multiple drug treatment for advanced head and neck cancer.
    British medical journal, 1975, Jul-05, Volume: 3, Issue:5974

    Topics: Antineoplastic Agents; Bleomycin; Doxorubicin; Drug Synergism; Drug Therapy, Combination; Ear Neopla

1975
[Experimental research in cycle-synchronizing radiotherapy].
    Acta stomatologica Belgica, 1975, Volume: 72, Issue:3

    Topics: Animals; Bleomycin; Facial Neoplasms; Fluorouracil; Humans; Maxillary Neoplasms

1975
[Peripheral blood morphological indices in the drug and radiation therapy of malignant tumors of the maxilla].
    Meditsinskaia radiologiia, 1979, Volume: 24, Issue:3

    Topics: Adult; Aged; Blood; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Male;

1979
[Treatment of maxillary cancer].
    Voprosy onkologii, 1978, Volume: 24, Issue:11

    Topics: Carubicin; Cyclophosphamide; Drug Therapy, Combination; Fluorouracil; Humans; Maxillary Neoplasms; M

1978
[An clinical evaluation of the combined therapy for maxillary sinus carcinoma with irradiation and the intraarterial infusion of 5-FU (author's transl)].
    Nihon Jibiinkoka Gakkai kaiho, 1976, Jun-20, Volume: 79, Issue:6

    Topics: Carcinoma, Squamous Cell; Drug Evaluation; Female; Fluorouracil; Humans; Injections, Intra-Arterial;

1976
[Radiotherapy combined with halogenated pyrimidines--fundamental and clinical studies (author's transl)].
    Nihon Gan Chiryo Gakkai shi, 1975, Sep-20, Volume: 10, Issue:3

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Female; Fluorouracil; Halogens; Head and Neck Neoplasm

1975
[A combined therapy for maxillary cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bromodeoxyuridine; Combined Modality Therapy;

1991
[Multidisciplinary treatment of head and neck cancer].
    Gan no rinsho. Japan journal of cancer clinics, 1985, Volume: 31, Issue:9 Suppl

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cisplatin

1985
[Preoperative chemotherapy for head and neck cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cisplatin; Fluorouracil; Head and Neck Ne

1985
A study of the late effects of radiotherapy and operation on patients with maxillary cancer. A survey more than 10 years after initial treatment.
    Cancer, 1988, Nov-15, Volume: 62, Issue:10

    Topics: Combined Modality Therapy; Fluorouracil; Humans; Maxillary Neoplasms; Postoperative Complications; R

1988
[Multidisciplinary treatment of the head and neck cancer--FAR therapy and its modification and application].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:4 Pt 2

    Topics: Adult; Aged; Combined Modality Therapy; Drug Resistance; Drug Therapy, Combination; Esophageal Neopl

1986
Analysis of the long-term results of our combination therapy for maxillary cancer, with particular reference to treatment of T4 and N1-3 maxillary cancer.
    Auris, nasus, larynx, 1985, Volume: 12 Suppl 2

    Topics: Adolescent; Adult; Age Factors; Aged; Carcinoma, Squamous Cell; Child; Child, Preschool; Combined Mo

1985
[Metabolism of 1-(2-tetrahydrofuryl)-5-fluorouracil (FT-207) in human maxillary cancer (OKK) cells in culture].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:6

    Topics: Cell Division; Cells, Cultured; Chromatography, Thin Layer; Cytosol; Fluorouracil; Humans; Maxillary

1985
[Chemotherapy by intra-arterial path in cancer of the "head and neck" region].
    Acta chirurgica Belgica, 1971, Volume: 70, Issue:4

    Topics: Antineoplastic Agents; Bleomycin; Facial Neoplasms; Fluorouracil; Head; Head and Neck Neoplasms; Hum

1971
Cylindroma of the right maxillary antrum. Case report.
    The Laryngoscope, 1967, Volume: 77, Issue:3

    Topics: Adult; Carcinoma, Adenoid Cystic; Fluorouracil; Humans; Infusions, Parenteral; Male; Maxillary Neopl

1967
[Results of treatment of maxillary cancer in our department and future problems].
    Nihon Jibiinkoka Gakkai kaiho, 1972, Volume: 75, Issue:10

    Topics: Fluorouracil; Humans; Japan; Maxillary Neoplasms; Postoperative Complications

1972
[Experience in radiotherapy with high-pressure oxygen in cancer of the maxillary sinus].
    Nihon Jibiinkoka Gakkai kaiho, 1972, Volume: 75, Issue:10

    Topics: Female; Fluorouracil; Humans; Hyperbaric Oxygenation; Male; Maxillary Neoplasms; Methods; Middle Age

1972
[Combined cytostatic and irradiation treatment of head and neck tumors using the synchronization effect].
    HNO, 1972, Volume: 20, Issue:1

    Topics: Aged; Cobalt Isotopes; Ear Neoplasms; Female; Fluorouracil; Head; Head and Neck Neoplasms; Humans; M

1972
[Effect and limitation of antineoplastic agents in otolaryngology. 2. Effect and evaluation of intra-arterial injection therapy].
    Nihon Jibiinkoka Gakkai kaiho, 1971, Volume: 74, Issue:2

    Topics: Ear Canal; Ear Neoplasms; Fluorouracil; Humans; Injections, Intra-Arterial; Maxillary Neoplasms

1971
[Therapy of malignant tumor of the head and neck region].
    Nihon Jibiinkoka Gakkai kaiho, 1971, Volume: 74, Issue:2

    Topics: Adult; Aged; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Male; Maxillary Neoplasms; Mi

1971
[Chemotherapy of malignant tumors in otorhinolaryngology--combined treatment with antitumor agents and MDS bby intra-arterial route].
    Nihon Jibiinkoka Gakkai kaiho, 1971, Volume: 74, Issue:12

    Topics: Dextrans; Female; Fluorouracil; Humans; Injections, Intra-Arterial; Maxillary Neoplasms; Middle Aged

1971
[Application of radiosensitizer, 5-bromodeoxyuridine, to head and neck tumors].
    Rinsho hoshasen. Clinical radiography, 1969, Volume: 14, Issue:10

    Topics: Bromodeoxyuridine; Fluorouracil; Humans; Injections, Intra-Arterial; Iodine Isotopes; Male; Maxillar

1969
[RRadiotherapy and radio-sensitizing agents].
    Rinsho hoshasen. Clinical radiography, 1971, Volume: 16, Issue:12

    Topics: Bromouracil; Fluorouracil; Humans; Maxillary Neoplasms; Radiation-Sensitizing Agents; Radiotherapy

1971
[The modification of the cell division rhythm in human tumors].
    Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1969, Volume: 193, Issue:2

    Topics: Adult; Aged; Autoradiography; Biopsy; Cell Division; Depression, Chemical; DNA, Neoplasm; Ear Neopla

1969
[Effect of 5-fluorouracil and bleomycin on malignant head and neck tumors].
    Jibi inkoka Otolaryngology, 1969, Volume: 41, Issue:11

    Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Female; Fluorouracil; Humans; Injec

1969
[Topical intra-arterial infusion of antineoplastic agents].
    Naika. Internal medicine, 1968, Volume: 22, Issue:3

    Topics: Adult; Aged; Antimetabolites; Catheterization; Female; Femoral Neoplasms; Fluorouracil; Humans; Inje

1968
[Combined therapy of irradiation and regional chemotherapy for cancer of the maxilla].
    Gan no rinsho. Japan journal of cancer clinics, 1968, Volume: 14, Issue:12

    Topics: Cobalt Isotopes; Fluorouracil; Humans; Maxillary Neoplasms; Prognosis

1968
Combined intra-arterial infusion and radiotherapy for the treatment of advanced cancer of the head and neck.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1969, Volume: 105, Issue:1

    Topics: Aged; Brain Neoplasms; Carcinoma, Squamous Cell; Esophageal Neoplasms; Fluorouracil; Follow-Up Studi

1969