fluorouracil has been researched along with Mast-Cell Sarcoma in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Mast-Cell Sarcoma: A unifocal malignant tumor that consists of atypical pathological MAST CELLS without systemic involvement. It causes local destructive growth in organs other than in skin or bone marrow.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Warrington, RC | 1 |
| Cheng, I | 1 |
| Fang, WD | 1 |
| Veselỳ, J | 1 |
| Cihák, A | 1 |
1 review available for fluorouracil and Mast-Cell Sarcoma
| Article | Year |
|---|---|
Resistance of mammalian tumour cells toward pyrimidine analogues. A review.
Topics: Animals; Antimetabolites; Azacitidine; Azauridine; Bromouracil; Carcinoma, Ehrlich Tumor; Cell Line; | 1973 |
1 other study available for fluorouracil and Mast-Cell Sarcoma
| Article | Year |
|---|---|
Effects of L-histidinol on the susceptibility of P815 mastocytoma cells to selected anticancer drugs in vitro and in DBA/2J mice.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Cy | 1987 |