fluorouracil has been researched along with Male Genitourinary Diseases in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The management of distal rectal cancer is in evolution." | 2.40 | Sphincter preservation in rectal cancer. Local excision followed by postoperative radiation therapy. ( Willett, CG, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Willett, CG | 1 |
1 review available for fluorouracil and Male Genitourinary Diseases
| Article | Year |
|---|---|
Sphincter preservation in rectal cancer. Local excision followed by postoperative radiation therapy.
Topics: Abdomen; Anal Canal; Antimetabolites, Antineoplastic; Carcinoma; Chemotherapy, Adjuvant; Colostomy; | 1998 |