Page last updated: 2024-10-27

fluorouracil and MODS

fluorouracil has been researched along with MODS in 6 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gurzu, S1
Jung, I1
Comsulea, M1
Kadar, Z1
Azamfirei, L1
Molnar, C1
Schwameis, M1
Thaler, J1
Schober, A1
Schörgenhofer, C1
Kulinna-Cosentini, C1
Laggner, A1
Röggla, M1
Jilma, B1
Schwartzman, AD1
Sethi, R1
Smith, R1
Lazar, A1
Mau-Holzmann, UA1
Kolb, H1
Reichenmiller, HE1
Riess, O1
Schömig, E1
Lim, WT1
McLeod, HL1
Bone, RC1

Reviews

1 review available for fluorouracil and MODS

ArticleYear
Multiorgan failure in a patient treated with the 5-fluorouracil, leucovorin, oxaliplatin, and irinotecan regimen.
    Clinical colorectal cancer, 2013, Volume: 12, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Duodenal Neoplasms; Fe

2013

Other Studies

5 other studies available for fluorouracil and MODS

ArticleYear
Lethal cardiotoxicity, steatohepatitis, chronic pancreatitis, and acute enteritis induced by capecitabine and oxaliplatin in a 36-year-old woman.
    Diagnostic pathology, 2013, Sep-16, Volume: 8

    Topics: Acute Disease; Adenocarcinoma; Adult; Ampulla of Vater; Antineoplastic Combined Chemotherapy Protoco

2013
Tranexamic acid and fibrinogen restore clotting in vitro and in vivo in cardiac thrombus associated hyperfibrinolysis with overt bleedings.
    Thrombosis and haemostasis, 2014, Volume: 112, Issue:5

    Topics: Adenocarcinoma; Aged; Anemia; Antifibrinolytic Agents; Antineoplastic Combined Chemotherapy Protocol

2014
Multiple organ failure due to 5-fluorouracil chemotherapy in a patient with a rare dihydropyrimidine dehydrogenase gene variant.
    Onkologie, 2004, Volume: 27, Issue:6

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Cecal Neoplasms; Dihydropyrimidine Dehydrogenase Defic

2004
Should screening for DPD deficiency be mandatory before 5-FU exposure?
    Onkologie, 2004, Volume: 27, Issue:6

    Topics: Antineoplastic Agents; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP

2004
A personal experience with SIRS and MODS.
    Critical care medicine, 1996, Volume: 24, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Humans; Interferons; Interleukin-2; Ma

1996