Page last updated: 2024-10-27

fluorouracil and MEA 2b

fluorouracil has been researched along with MEA 2b in 1 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Finally, unlike differentiated thyroid cancer, there is no known effective systemic therapy for MTC."2.43Medullary thyroid carcinoma: including MEN 2A and MEN 2B syndromes. ( Moley, JF; Quayle, FJ, 2005)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Quayle, FJ1
Moley, JF1

Reviews

1 review available for fluorouracil and MEA 2b

ArticleYear
Medullary thyroid carcinoma: including MEN 2A and MEN 2B syndromes.
    Journal of surgical oncology, 2005, Mar-01, Volume: 89, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Calcitonin; Carcinoma, Medullary; Combined Modality

2005