fluorouracil has been researched along with Lymphoma, T-Cell in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Lymphoma, T-Cell: A group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-fluorouracil (5-FU) has been successfully used to control (or cure) a variety of tumors, but has been only rarely applied to tumors of the lymphoid lineage." | 1.32 | Customized mitogen or antibody treatments enhance the sensitivity of lymphoid tumors to 5-fluorouracil in vitro and in vivo. ( D'Costa, S; Hurwitz, JL, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| D'Costa, S | 1 |
| Hurwitz, JL | 2 |
| D'Costa, SS | 1 |
2 other studies available for fluorouracil and Lymphoma, T-Cell
| Article | Year |
|---|---|
Customized mitogen or antibody treatments enhance the sensitivity of lymphoid tumors to 5-fluorouracil in vitro and in vivo.
Topics: Animals; Antibodies, Monoclonal; CD40 Antigens; Cell Division; Cell Membrane; Drug Synergism; Fluoro | 2003 |
Phytohemagglutinin inhibits lymphoid tumor growth in vitro and in vivo.
Topics: Animals; Annexin A5; Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Drug Combinations; Drug | 2003 |