fluorouracil has been researched along with Lymphoma, Large B-Cell, Diffuse in 24 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Lymphoma, Large B-Cell, Diffuse: Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (54.17) | 18.7374 |
| 1990's | 7 (29.17) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Azuma, A | 1 |
| Nakajima, Y | 1 |
| Nishizono, N | 1 |
| Minakawa, N | 1 |
| Suzuki, M | 1 |
| Hanaoka, K | 1 |
| Kobayashi, T | 2 |
| Tanaka, M | 1 |
| Sasaki, T | 1 |
| Matsuda, A | 1 |
| Hernández-Aragüés, I | 1 |
| Baniandrés-Rodríguez, O | 1 |
| Vilas-Boas, PT | 1 |
| Conde-Montero, E | 1 |
| Suárez-Fernández, R | 1 |
| Magyari, F | 1 |
| Barna, S | 1 |
| Miltényi, Z | 1 |
| Rajnai, H | 1 |
| Csomor, J | 1 |
| Udvardy, M | 1 |
| Illés, Á | 1 |
| Váróczy, L | 1 |
| De Stefani, A | 1 |
| Boffano, P | 1 |
| Bongioannini, G | 1 |
| Hawkes, EA | 1 |
| Okines, AF | 1 |
| Plummer, C | 1 |
| Cunningham, D | 1 |
| BRINDLEY, CO | 1 |
| KARNOFSKY, DA | 1 |
| MYHRE, K | 1 |
| FJAERLI, J | 1 |
| Lee, BC | 1 |
| Shav-Tal, Y | 1 |
| Peled, A | 1 |
| Gothelf, Y | 1 |
| Jiang, W | 1 |
| Toledo, J | 1 |
| Ploemacher, RE | 1 |
| Haran-Ghera, N | 1 |
| Zipori, D | 1 |
| Zinzani, PL | 1 |
| Pileri, S | 1 |
| Bendandi, M | 1 |
| Buzzi, M | 1 |
| Sabattini, E | 1 |
| Ascani, S | 1 |
| Gherlinzoni, F | 1 |
| Magagnoli, M | 1 |
| Albertini, P | 1 |
| Tura, S | 1 |
| Osswald, H | 1 |
| Youssef, M | 1 |
| Guglielmi, C | 4 |
| Amadori, S | 4 |
| Martelli, M | 4 |
| Papa, G | 2 |
| Mandelli, F | 4 |
| Coluzzi, S | 1 |
| Dragoni, F | 1 |
| Gary-Bobo, J | 1 |
| Fain, WR | 1 |
| Conn, JH | 1 |
| Chavez, CM | 1 |
| Takatani, O | 1 |
| Hattori, N | 1 |
| Kimura, K | 1 |
| Armstrong, JG | 1 |
| Kühböck, J | 1 |
| Pokorny, D | 1 |
| Steinbach, K | 1 |
| Eggerth, G | 1 |
| Goto, M | 1 |
| Muramoto, S | 1 |
| Nakagaki, K | 1 |
| Alberto, P | 1 |
| Astrakhan, VI | 1 |
| Stutzman, L | 1 |
5 trials available for fluorouracil and Lymphoma, Large B-Cell, Diffuse
| Article | Year |
|---|---|
Clinical implications of serum levels of soluble CD30 in 70 adult anaplastic large-cell lymphoma patients.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cyta | 1998 |
F-MACHOP in advanced aggressive lymphoma.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Do | 1992 |
The F-MACHOP sequential combination chemotherapy regimen in advanced diffuse aggressive lymphomas: long-term results.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Protocols; Cyclophospham | 1991 |
[Main problems of the method of clinical study of new antineoplastic agents].
Topics: Antineoplastic Agents; Biopsy; Clinical Trials as Topic; Female; Fluorouracil; Humans; Intestinal Po | 1966 |
Combined radiotherapy and chemotherapy of lymphomas and other cancers.
Topics: Clinical Trials as Topic; Cyclophosphamide; Dactinomycin; Fluorouracil; Follow-Up Studies; Hematopoi | 1971 |
19 other studies available for fluorouracil and Lymphoma, Large B-Cell, Diffuse
| Article | Year |
|---|---|
Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum.
Topics: Adenine; Animals; Antineoplastic Agents; Cytarabine; Female; Fluorouracil; Humans; Leukemia L1210; L | 1993 |
Cutaneous drug Reactions: Chemotherapy-induced hyperpigmentation.
Topics: Adenocarcinoma; Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy | 2017 |
Histopathological difficulties in an adolescent lymphoma patient.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Fluoroura | 2015 |
The management of an orbital diffuse large B-cell lymphoma.
Topics: Aged; Antibiotics, Antineoplastic; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined C | 2014 |
Cardiotoxicity in patients treated with bevacizumab is potentially reversible.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Mono | 2011 |
METHODOLOGY OF PRELIMINARY CHEMOTHERAPEUTIC TRIALS IN PATIENTS WITH MALIGNANT SOLID TUMORS.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Colonic Neoplasms; Cyclophosp | 1963 |
NONSURGICAL TREATMENT OF PULMONARY CANCER.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agen | 1964 |
TREATMENT OF MALIGNANT TUMOURS WITH 5-FLUOROURACIL IN 80 PATIENTS.
Topics: Biomedical Research; Breast Neoplasms; Colonic Neoplasms; Drug Therapy; Esophageal Neoplasms; Female | 1964 |
A hematopoietic organ-specific 49-kD nuclear antigen: predominance in immature normal and tumor granulocytes and detection in hematopoietic precursor cells.
Topics: Acute Disease; Animals; Antigens, Neoplasm; Bone Marrow; Cell Differentiation; Cell Nucleus; Cells, | 1996 |
Potentiation of the chemotherapeutic action of 5-fluorouracil by combination with cytidine or guanosine on HRS-sarcoma.
Topics: Animals; Cytidine; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Guanosine; Lymph | 1979 |
The F-MACHOP regimen in advanced diffuse aggressive lymphomas: summary of ten years' experience at a single institution.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Fluoroura | 1991 |
Clinical and pathological restaging in aggressive non-Hodgkin's lymphomas.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Doxorubicin; Fe | 1991 |
[Mitomycin alone and in therapeutic association in the palliative treatment of solid tumors].
Topics: Antineoplastic Agents; Breast Neoplasms; Cobalt Isotopes; Cyclophosphamide; Drug Combinations; Femal | 1971 |
Continuous arterial infusion chemotherapy. Experience with 44 cases.
Topics: Adenocarcinoma; Arteries; Brain Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Cath | 1967 |
Echographic evaluation of abdominal tumor regression during antineoplastic treatment.
Topics: Abdominal Neoplasms; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorub | 1974 |
Current problems in the use of the oncolytic drugs.
Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dac | 1968 |
[Polychemotherapy of malignant tumors and hemoblastoses].
Topics: Adenocarcinoma; Adult; Aged; Alkylating Agents; Antineoplastic Agents; Bronchial Neoplasms; Carcinom | 1968 |
[Experience with 5-fluorouracil in malignant skin tumors].
Topics: Adult; Aged; Female; Fluorouracil; Humans; Leukemia, Lymphoid; Lymphoma, Large B-Cell, Diffuse; Male | 1967 |
[Progress in chemotherapy of solid tumors and malignant lymphomas (continued)].
Topics: Adult; Antineoplastic Agents; Carcinoma; Choriocarcinoma; Female; Fluorouracil; Gonadal Steroid Horm | 1967 |