fluorouracil has been researched along with Lymphedema in 12 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Lymphedema: Edema due to obstruction of lymph vessels or disorders of the lymph nodes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with sodium selenite is well tolerated and easy to deliver." | 2.71 | Selenium in the treatment of radiation-associated secondary lymphedema. ( Bruns, F; Büntzel, J; DeVries, AF; Glatzel, M; Kisters, K; Micke, O; Mücke, R; Schäfer, U; Schönekaes, K, 2003) |
| "Lymphedema was measured in 14%, of the irradiated patients versus 3% of the non-irradiated patients (NS)." | 2.69 | Late treatment-related morbidity in breast cancer patients randomized to postmastectomy radiotherapy and systemic treatment versus systemic treatment alone. ( Andersen, J; Højris, I; Overgaard, J; Overgaard, M, 2000) |
| "Lymphedema was defined as a >2-cm difference in forearm circumference compared with the untreated side." | 2.42 | Risk of lymphedema after regional nodal irradiation with breast conservation therapy. ( Assaad, SI; Coen, JJ; Kachnic, LA; Powell, SN; Taghian, AG, 2003) |
| "Although squamous cell carcinoma (SCC) is the second most common nonmelanoma skin cancer, clinicians have difficulty diagnosing SCC of the toe because its clinical features can mimic other less serious diseases." | 1.43 | A Digital Squamous Cell Carcinoma Mimicking a Diabetic Foot Ulcer, With Early Inguinal Metastasis and Cancer-Related Lymphedema. ( Kim, HW; Kim, JE; Ko, JY; Kwon, HI; Park, HC; Ro, YS, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 5 (41.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Fronek, L | 1 |
| Harrison, A | 1 |
| Cooper, H | 1 |
| Dorton, D | 1 |
| Hopkins, JO | 1 |
| Allred, J | 1 |
| Hurria, A | 1 |
| Jatoi, A | 1 |
| Lafky, JM | 1 |
| Cohen, H | 1 |
| Hudis, C | 1 |
| Winer, E | 1 |
| Mandelblatt, J | 1 |
| Partridge, A | 1 |
| Carey, L | 1 |
| Muss, HB | 1 |
| Dalenc, F | 1 |
| Ribet, V | 1 |
| Rossi, AB | 1 |
| Guyonnaud, J | 1 |
| Bernard-Marty, C | 1 |
| de Lafontan, B | 1 |
| Salas, S | 1 |
| Ranc Royo, AL | 1 |
| Sarda, C | 1 |
| Levasseur, N | 1 |
| Massabeau, C | 1 |
| Levecq, JM | 1 |
| Dulguerova, P | 1 |
| Guerrero, D | 1 |
| Sibaud, V | 1 |
| Lee, MJ | 1 |
| Beith, J | 1 |
| Ward, L | 1 |
| Kilbreath, S | 1 |
| Park, HC | 1 |
| Kwon, HI | 1 |
| Kim, HW | 1 |
| Kim, JE | 1 |
| Ro, YS | 1 |
| Ko, JY | 1 |
| Wang, PL | 1 |
| Cheng, YB | 1 |
| Kuerban, G | 1 |
| Coen, JJ | 1 |
| Taghian, AG | 1 |
| Kachnic, LA | 1 |
| Assaad, SI | 1 |
| Powell, SN | 1 |
| Micke, O | 1 |
| Bruns, F | 1 |
| Mücke, R | 1 |
| Schäfer, U | 1 |
| Glatzel, M | 1 |
| DeVries, AF | 1 |
| Schönekaes, K | 1 |
| Kisters, K | 1 |
| Büntzel, J | 1 |
| White, JD | 1 |
| Junor, EJ | 1 |
| McGarva, J | 1 |
| McManners, J | 1 |
| Holland, IS | 1 |
| Højris, I | 1 |
| Andersen, J | 1 |
| Overgaard, M | 1 |
| Overgaard, J | 1 |
| Grattan, CE | 1 |
| Guerrier, CJ | 1 |
| Dean, RE | 1 |
| Taylor, ES | 1 |
| Weisbrod, DM | 1 |
| Martin, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Role of Sodium Selenite Supplementation in Patients With Locally Advanced Head and Neck Cancer Undergoing Concurrent Chemoradiotherapy[NCT05451576] | 60 participants (Anticipated) | Interventional | 2020-08-12 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for fluorouracil and Lymphedema
| Article | Year |
|---|---|
Risk of lymphedema after regional nodal irradiation with breast conservation therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Axilla; Boston; Breast Neoplasms; Chemotherapy, Adju | 2003 |
4 trials available for fluorouracil and Lymphedema
| Article | Year |
|---|---|
Lymphedema, musculoskeletal events and arm function in older patients receiving adjuvant chemotherapy for breast cancer (Alliance A171302).
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arm; Breast Neoplasms; Cape | 2017 |
Efficacy of a global supportive skin care programme with hydrotherapy after non-metastatic breast cancer treatment: A randomised, controlled study.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; | 2018 |
Selenium in the treatment of radiation-associated secondary lymphedema.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ci | 2003 |
Late treatment-related morbidity in breast cancer patients randomized to postmastectomy radiotherapy and systemic treatment versus systemic treatment alone.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Drug Admin | 2000 |
7 other studies available for fluorouracil and Lymphedema
| Article | Year |
|---|---|
Intralesional 5-fluorouracil utilizing abbreviated tourniquet device in patients with overlying stasis dermatitis or lymphedema.
Topics: Antimetabolites, Antineoplastic; Fluorouracil; Humans; Injections, Intralesional; Lymphedema; Skin N | 2021 |
Lymphedema following taxane-based chemotherapy in women with early breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arm; Australia; Breast Neoplasms; Cyclophosphamide; | 2014 |
A Digital Squamous Cell Carcinoma Mimicking a Diabetic Foot Ulcer, With Early Inguinal Metastasis and Cancer-Related Lymphedema.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Carcinoma, Squamous Cell; | 2016 |
The clinical characteristic differences between thrombosis-related edema and lymphedema following radiotherapy or chemoradiotherapy for patients with cervical cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy | 2012 |
Adenocarcinoma of the salivary gland? A chemo-sensitive disease.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Epirubicin; Fluorouracil; | 2004 |
Reaction to topical fluorouracil of secondary lymphedema.
Topics: Aged; Drug Eruptions; Facial Dermatoses; Female; Fluorouracil; Humans; Lymphedema; Ointments | 1985 |
The treatment of premalignant and malignant lesions of the vulva.
Topics: Administration, Topical; Adult; Aged; Carcinoma in Situ; Carcinoma, Squamous Cell; Female; Fluoroura | 1974 |