fluorouracil has been researched along with Lyme Disease in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Lyme Disease: An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe. It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations. The disease was formerly known as Lyme arthritis and first discovered at Old Lyme, Connecticut.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Barbour-Stoenner-Kelly (BSK) II medium containing fosfomycin, 5-fluorouracil, trimethoprim and sulfamethoxazole was evaluated for the selective isolation of the Borrelia species responsible for Lyme disease and relapsing fever." | 3.68 | Evaluation of agents for use in medium for selective isolation of Lyme disease and relapsing fever Borrelia species. ( Konishi, H; Morshed, MG; Nakazawa, T; Nishimura, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morshed, MG | 1 |
| Konishi, H | 1 |
| Nishimura, T | 1 |
| Nakazawa, T | 1 |
1 other study available for fluorouracil and Lyme Disease
| Article | Year |
|---|---|
Evaluation of agents for use in medium for selective isolation of Lyme disease and relapsing fever Borrelia species.
Topics: Bacteriological Techniques; Borrelia; Culture Media; Drug Combinations; Fluorouracil; Fosfomycin; Ly | 1993 |