fluorouracil has been researched along with Lung Diseases in 9 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Lung Diseases: Pathological processes involving any part of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, it was repeatedly shown that the sequence of 5-FU followed by CDDP is more active and less toxic in tumor-bearing animals." | 1.33 | Schedule-dependent antitumor activity and toxicity of combinations of 5-fluorouracil and cisplatin/carboplatin against L1210 leukemia-bearing mice. ( Fujimoto, S, 2006) |
| "Twenty-seven patients with squamous cell carcinoma of the head and neck were treated with bleomycin 7." | 1.27 | Bleomycin infusion followed by cyclophosphamide, methotrexate, and 5-fluorouracil in advanced squamous carcinoma of the head and neck. ( Biller, H; Brooks, S; Holland, JF; Ohnuma, T; Plasse, TF; Saponaro, E, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uno, H | 1 |
| Shida, T | 1 |
| Ogasawara, T | 1 |
| Nomura, S | 1 |
| Takahara, Y | 1 |
| Sato, Y | 1 |
| Komatu, T | 1 |
| Takahashi, M | 1 |
| Fujimoto, S | 1 |
| Hanazono, K | 1 |
| Natsugoe, S | 1 |
| Okumura, H | 1 |
| Matsumoto, M | 1 |
| Oowaki, T | 1 |
| Setoyama, T | 1 |
| Hiraki, Y | 1 |
| Arimura, K | 1 |
| Nakamura, F | 1 |
| Nakajo, M | 1 |
| Aikou, T | 1 |
| Gunstream, SR | 1 |
| Seidenfeld, JJ | 1 |
| Sobonya, RE | 1 |
| McMahon, LJ | 1 |
| Plasse, TF | 1 |
| Ohnuma, T | 1 |
| Brooks, S | 1 |
| Saponaro, E | 1 |
| Holland, JF | 1 |
| Biller, H | 1 |
| Nishinakamura, R | 1 |
| Miyajima, A | 1 |
| Mee, PJ | 1 |
| Tybulewicz, VL | 1 |
| Murray, R | 1 |
| Chabner, BA | 1 |
| Myers, CE | 1 |
| Coleman, CN | 1 |
| Johns, DG | 1 |
| Krauss, S | 1 |
| Sonoda, T | 1 |
| Solomon, A | 1 |
| Flubacher, P | 1 |
| Meier, V | 1 |
| Obrecht, JP | 1 |
| Hartmann, D | 1 |
1 review available for fluorouracil and Lung Diseases
| Article | Year |
|---|---|
The clinical pharmacology of antineoplastic agents (first of two parts).
Topics: Animals; Antineoplastic Agents; Asparaginase; Binding Sites; Biological Transport; Chemical and Drug | 1975 |
8 other studies available for fluorouracil and Lung Diseases
| Article | Year |
|---|---|
[A Case Report of Clinical Complete Response with Chemotherapy for Descending Colon Cancer Complicated with Severe Pulmonary Dysfunction].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Colon, Descending; Colonic Neopl | 2016 |
Schedule-dependent antitumor activity and toxicity of combinations of 5-fluorouracil and cisplatin/carboplatin against L1210 leukemia-bearing mice.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascites; Carboplatin | 2006 |
[An effective treatment by chemoradiation therapy after stent insertion for advanced esophageal cancer with esophago-pulmonary fistula--report of a case].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali | 2007 |
Mitomycin-associated lung disease.
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Cisplatin; Cyclophosphamide; Drug Therapy, Combinatio | 1983 |
Bleomycin infusion followed by cyclophosphamide, methotrexate, and 5-fluorouracil in advanced squamous carcinoma of the head and neck.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Carcinoma, Squamous Cell; Cy | 1984 |
Hematopoiesis in mice lacking the entire granulocyte-macrophage colony-stimulating factor/interleukin-3/interleukin-5 functions.
Topics: Animals; Bone Marrow; Crosses, Genetic; Eosinophils; Fluorouracil; Granulocyte-Macrophage Colony-Sti | 1996 |
Treatment of advanced gastrointestinal cancer with 5-fluorouracil and mitomycin C.
Topics: Adenocarcinoma; Adult; Aged; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Gas | 1979 |
[Cytostatic pneumopathy following chemotherapy for metastasizing breast neoplasm].
Topics: Aged; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Ethinyl Estradiol; Female; Femo | 1977 |