fluorouracil has been researched along with Long Sleeper Syndrome in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sleep disorders are prevalent in patients with advanced cancer." | 2.80 | Subjective sleep and overall survival in chemotherapy-naïve patients with metastatic colorectal cancer. ( Bjarnason, GA; Giacchetti, S; Innominato, PF; Lévi, F; Palesh, O; Spiegel, D; Ulusakarya, A, 2015) |
| "Fatigue was assessed with the Multidimensional Fatigue Symptom Inventory-Short Form (MFSI-SF)." | 1.38 | The longitudinal relationship between fatigue and sleep in breast cancer patients undergoing chemotherapy. ( Ancoli-Israel, S; Dimsdale, JE; Fiorentino, L; Liu, L; Mills, PJ; Natarajan, L; Parker, BA; Rissling, M; Sadler, GR, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chaoul, A | 1 |
| Milbury, K | 1 |
| Spelman, A | 1 |
| Basen-Engquist, K | 1 |
| Hall, MH | 1 |
| Wei, Q | 1 |
| Shih, YT | 1 |
| Arun, B | 1 |
| Valero, V | 1 |
| Perkins, GH | 1 |
| Babiera, GV | 1 |
| Wangyal, T | 1 |
| Engle, R | 1 |
| Harrison, CA | 1 |
| Li, Y | 1 |
| Cohen, L | 1 |
| Innominato, PF | 1 |
| Spiegel, D | 1 |
| Ulusakarya, A | 1 |
| Giacchetti, S | 2 |
| Bjarnason, GA | 1 |
| Lévi, F | 2 |
| Palesh, O | 1 |
| Liu, L | 1 |
| Rissling, M | 1 |
| Natarajan, L | 1 |
| Fiorentino, L | 1 |
| Mills, PJ | 1 |
| Dimsdale, JE | 1 |
| Sadler, GR | 1 |
| Parker, BA | 1 |
| Ancoli-Israel, S | 1 |
| Emens, LA | 1 |
| Kennedy, MJ | 1 |
| Fetting, JH | 1 |
| Davidson, NE | 1 |
| Garrett, E | 1 |
| Armstrong, DK | 1 |
| Mormont, MC | 1 |
| Waterhouse, J | 1 |
| Bleuzen, P | 1 |
| Jami, A | 1 |
| Bogdan, A | 1 |
| Lellouch, J | 1 |
| Misset, JL | 1 |
| Touitou, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Developing and Examining Preliminary Effects of An Innovative Care-improvement Smartphone-based Perioperative Solution for Women Undergoing Breast Cancer Surgery (iCareBreast): A Pilot Randomized Controlled Trial[NCT04172350] | 112 participants (Anticipated) | Interventional | 2019-11-19 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for fluorouracil and Long Sleeper Syndrome
| Article | Year |
|---|---|
Randomized trial of Tibetan yoga in patients with breast cancer undergoing chemotherapy.
Topics: Actigraphy; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neo | 2018 |
Subjective sleep and overall survival in chemotherapy-naïve patients with metastatic colorectal cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chronotherapy; Colorectal Neoplasms; Fe | 2015 |
A phase I toxicity and feasibility trial of sequential dose-dense induction chemotherapy with doxorubicin, paclitaxel, and 5-fluorouracil followed by high dose consolidation for high-risk primary breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Breast Neoplasms; Diarrhea; | 2002 |
Marked 24-h rest/activity rhythms are associated with better quality of life, better response, and longer survival in patients with metastatic colorectal cancer and good performance status.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Circadian Rhythm; Colorectal Neoplasms; | 2000 |
1 other study available for fluorouracil and Long Sleeper Syndrome
| Article | Year |
|---|---|
The longitudinal relationship between fatigue and sleep in breast cancer patients undergoing chemotherapy.
Topics: Actigraphy; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cross-Sectional Studie | 2012 |