Page last updated: 2024-10-27

fluorouracil and Linitis Plastica

fluorouracil has been researched along with Linitis Plastica in 5 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Linitis Plastica: A condition where the stomach wall becomes thickened, rubbery and loses its ability to distend. The stomach assumes a leather bottle shape. It is most often seen in adenocarcinoma of the stomach. The term is often used synonymously with diffuse adenocarcinoma of the stomach.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Le Naourès, C1
Guilloit, JM1
Capovilla, M1
Chaudhry, NA1
Zahid, K1
Coman, R1
Zhang, Q1
Sasaki, T1
Koizumi, W1
Tanabe, S1
Higuchi, K1
Nakayama, N1
Saigenji, K1
Murayama, H1
Miura, K1
Sakamoto, J1
Sato, S1
Iwasaki, K1
Torisu, M1

Reviews

1 review available for fluorouracil and Linitis Plastica

ArticleYear
Primary linitis plastica of the rectum: report of four cases and review of the literature.
    Surgery today, 1996, Volume: 26, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

1996

Other Studies

4 other studies available for fluorouracil and Linitis Plastica

ArticleYear
[A "lymph node" of the hepatic hilum].
    Annales de pathologie, 2013, Volume: 33, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bile Ducts, Intrahepatic; Cholecystectomy; Cisplatin

2013
Jackhammer oesophagus in a case of linitis plastica.
    BMJ case reports, 2016, May-12, Volume: 2016

    Topics: Cisplatin; Colonoscopy; Diagnosis, Differential; Docetaxel; Esophagus; Fatal Outcome; Female; Fluoro

2016
TS-1 as first-line therapy for gastric linitis plastica: historical control study.
    Anti-cancer drugs, 2006, Volume: 17, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Combinations; Female; F

2006
A case of linitis plastica of the rectum treated by pelvic exenteration after aggressive immunochemotherapy.
    Surgery today, 1992, Volume: 22, Issue:2

    Topics: Adult; Combined Modality Therapy; Fluorouracil; Humans; Infusions, Intra-Arterial; Injections, Intra

1992