fluorouracil has been researched along with Leukoplakia, Oral in 6 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Leukoplakia, Oral: A white patch seen on the oral mucosa. It is considered a premalignant condition and is often tobacco-induced. When evidence of Epstein-Barr virus is present, the condition is called hairy leukoplakia (LEUKOPLAKIA, HAIRY).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zide, MF | 1 |
| Warnock, GR | 1 |
| Fuller, RP | 1 |
| Pelleu, GB | 1 |
| Zöller, J | 1 |
| Maier, H | 1 |
| Flentje, M | 1 |
| Born, IA | 1 |
| Osswald, H | 1 |
| Amagasa, T | 1 |
| Michi, K | 1 |
| Totsuka, M | 1 |
| Asada, K | 1 |
| Masuo, K | 1 |
| Klein, E | 1 |
| Stoll, HL | 1 |
| Milgrom, H | 1 |
| Helm, F | 1 |
| Walker, MJ | 1 |
| Montero, ED | 1 |
| Di Piramo, S | 1 |
6 other studies available for fluorouracil and Leukoplakia, Oral
| Article | Year |
|---|---|
Actinic keratosis: from the skin to the lip.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biopsy; Chemexfoliation; Cryosurgery; Elec | 2008 |
Evaluation of 5-fluorouracil in the treatment of actinic keratosis of the lip.
Topics: Administration, Topical; Drug Evaluation; Fluorouracil; Humans; Leukoplakia, Oral; Lip Diseases | 1981 |
[Effect of a cisplatin-5-fluorouracil combination chemotherapy on malignant transformation of the epithelium of mouth mucosa].
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Di | 1994 |
[The effect of local administration of 5-fluorouracil in leukoplakia of the oral mucous membrane (author's transl)].
Topics: Fluorouracil; Humans; Leukoplakia, Oral | 1975 |
Tumors of the skin. XII. Topical 5-Fluorouracil for epidermal neoplasms.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatitis; Esthetics; Female; Fluorouracil; Humans | 1971 |
[Tropical treatment of oral leukoplakia with 5-fluorouracil].
Topics: Fluorouracil; Leukoplakia, Oral | 1970 |