Page last updated: 2024-10-27

fluorouracil and Leukoplakia, Oral

fluorouracil has been researched along with Leukoplakia, Oral in 6 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Leukoplakia, Oral: A white patch seen on the oral mucosa. It is considered a premalignant condition and is often tobacco-induced. When evidence of Epstein-Barr virus is present, the condition is called hairy leukoplakia (LEUKOPLAKIA, HAIRY).

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zide, MF1
Warnock, GR1
Fuller, RP1
Pelleu, GB1
Zöller, J1
Maier, H1
Flentje, M1
Born, IA1
Osswald, H1
Amagasa, T1
Michi, K1
Totsuka, M1
Asada, K1
Masuo, K1
Klein, E1
Stoll, HL1
Milgrom, H1
Helm, F1
Walker, MJ1
Montero, ED1
Di Piramo, S1

Other Studies

6 other studies available for fluorouracil and Leukoplakia, Oral

ArticleYear
Actinic keratosis: from the skin to the lip.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2008, Volume: 66, Issue:6

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biopsy; Chemexfoliation; Cryosurgery; Elec

2008
Evaluation of 5-fluorouracil in the treatment of actinic keratosis of the lip.
    Oral surgery, oral medicine, and oral pathology, 1981, Volume: 52, Issue:5

    Topics: Administration, Topical; Drug Evaluation; Fluorouracil; Humans; Leukoplakia, Oral; Lip Diseases

1981
[Effect of a cisplatin-5-fluorouracil combination chemotherapy on malignant transformation of the epithelium of mouth mucosa].
    HNO, 1994, Volume: 42, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Di

1994
[The effect of local administration of 5-fluorouracil in leukoplakia of the oral mucous membrane (author's transl)].
    Nihon Koku Geka Gakkai zasshi, 1975, Volume: 21, Issue:5

    Topics: Fluorouracil; Humans; Leukoplakia, Oral

1975
Tumors of the skin. XII. Topical 5-Fluorouracil for epidermal neoplasms.
    Journal of surgical oncology, 1971, Volume: 3, Issue:3

    Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dermatitis; Esthetics; Female; Fluorouracil; Humans

1971
[Tropical treatment of oral leukoplakia with 5-fluorouracil].
    Anales de la Facultad de Odontologia, 1970, Issue:14

    Topics: Fluorouracil; Leukoplakia, Oral

1970