fluorouracil has been researched along with Leukemia, T-Cell in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Leukemia, T-Cell: A malignant disease of the T-LYMPHOCYTES in the bone marrow, thymus, and/or blood.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asai, S | 1 |
| Miyachi, H | 1 |
| Kobayashi, H | 1 |
| Takemura, Y | 1 |
| Ando, Y | 1 |
| Sugimoto, K | 1 |
| Taniguchi, S | 1 |
| Ogata, H | 1 |
| Ikehara, S | 1 |
| Fujita, J | 1 |
| Mori, KJ | 1 |
2 other studies available for fluorouracil and Leukemia, T-Cell
| Article | Year |
|---|---|
Large diversity in transport-mediated methotrexate resistance in human leukemia cell line CCRF-CEM established in a high concentration of leucovorin.
Topics: Amino Acid Substitution; Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Co | 2003 |
Production of a negative regulator of IL-3 by bone marrow cells in response to the supernatant of IL-3-producing STIL-3 leukemia cells.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Colony-Forming Units Assay; Culture Media, Conditioned; Flu | 1992 |