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fluorouracil and Leukemia, Promyelocytic, Acute

fluorouracil has been researched along with Leukemia, Promyelocytic, Acute in 7 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Leukemia, Promyelocytic, Acute: An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.

Research Excerpts

ExcerptRelevanceReference
"Sarcoma 180 was used as in vivo model."1.38In vitro and in vivo anticancer properties of cucurbitacin isolated from Cayaponia racemosa. ( Alves, AP; Chaves, DC; Costa-Lotufo, LV; Dantas, IN; Ferreira, PM; Militão, GC; Monte, FJ; Odorico de Moraes, M; Pessoa, C, 2012)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheng, CC1
Dong, Q1
Liu, DF1
Luo, YL1
Liu, LF1
Chen, AY1
Yu, C1
Savaraj, N1
Chou, TC1
Rashidi, A1
Man, L1
Howard, JR1
Atienza, D1
Fisher, SI1
Kara, O1
Ozdemir, E1
Arslan, C1
Dogan, E1
Altundag, K1
Militão, GC1
Dantas, IN1
Ferreira, PM1
Alves, AP1
Chaves, DC1
Monte, FJ1
Pessoa, C1
Odorico de Moraes, M1
Costa-Lotufo, LV1
Grau Cat, J1
Navarro Ferrando, JT1
Mate Sanz, JL1
Ribera Santasusana, JM1
Kafka, M1
Dvilansky, A1
Nathan, I1
Pályi, I1

Other Studies

7 other studies available for fluorouracil and Leukemia, Promyelocytic, Acute

ArticleYear
Design of antineoplastic agents on the basis of the "2-phenylnaphthalene-type" structural pattern. 2. Synthesis and biological activity studies of benzo]b]naphtho[2,3-d]furan-6,11-dione derivatives.
    Journal of medicinal chemistry, 1993, Dec-10, Volume: 36, Issue:25

    Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; DNA Topoisomerases, Type II; Furans; Humans

1993
Therapy-related acute promyelocytic leukemia after chemoradiotherapy with capecitabine for rectal adenocarcinoma.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:3

    Topics: Antimetabolites, Antineoplastic; Bone Marrow; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Leu

2014
Acute promyelocytic leukemia in a young patient with breast cancer.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubici

2011
In vitro and in vivo anticancer properties of cucurbitacin isolated from Cayaponia racemosa.
    Pharmaceutical biology, 2012, Volume: 50, Issue:12

    Topics: Adolescent; Adult; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineopla

2012
[Acute promyelocytic leukemia in a patient with colon adenocarcinoma treated with fluorouracil].
    Medicina clinica, 2007, Mar-31, Volume: 128, Issue:12

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Colonic Neoplasms; Fluorouracil; Humans; Leukemia,

2007
Mechanism of interaction between interferon-gamma and antineoplastic agent on the differentiation of HL-60 promyelocytic cells.
    Experimental hematology, 1990, Volume: 18, Issue:3

    Topics: Cell Differentiation; Cell Division; Cycloheximide; Dactinomycin; Drug Synergism; Fluorouracil; Huma

1990
Heterogeneity of the response to inducers of differentiation and to cytostatics of tumor cell populations.
    Pathology, research and practice, 1988, Volume: 184, Issue:1

    Topics: Antineoplastic Agents; Cell Differentiation; Cisplatin; Cytarabine; Dacarbazine; Dimethyl Sulfoxide;

1988