fluorouracil has been researched along with Leukemia, Promyelocytic, Acute in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Leukemia, Promyelocytic, Acute: An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sarcoma 180 was used as in vivo model." | 1.38 | In vitro and in vivo anticancer properties of cucurbitacin isolated from Cayaponia racemosa. ( Alves, AP; Chaves, DC; Costa-Lotufo, LV; Dantas, IN; Ferreira, PM; Militão, GC; Monte, FJ; Odorico de Moraes, M; Pessoa, C, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, CC | 1 |
| Dong, Q | 1 |
| Liu, DF | 1 |
| Luo, YL | 1 |
| Liu, LF | 1 |
| Chen, AY | 1 |
| Yu, C | 1 |
| Savaraj, N | 1 |
| Chou, TC | 1 |
| Rashidi, A | 1 |
| Man, L | 1 |
| Howard, JR | 1 |
| Atienza, D | 1 |
| Fisher, SI | 1 |
| Kara, O | 1 |
| Ozdemir, E | 1 |
| Arslan, C | 1 |
| Dogan, E | 1 |
| Altundag, K | 1 |
| Militão, GC | 1 |
| Dantas, IN | 1 |
| Ferreira, PM | 1 |
| Alves, AP | 1 |
| Chaves, DC | 1 |
| Monte, FJ | 1 |
| Pessoa, C | 1 |
| Odorico de Moraes, M | 1 |
| Costa-Lotufo, LV | 1 |
| Grau Cat, J | 1 |
| Navarro Ferrando, JT | 1 |
| Mate Sanz, JL | 1 |
| Ribera Santasusana, JM | 1 |
| Kafka, M | 1 |
| Dvilansky, A | 1 |
| Nathan, I | 1 |
| Pályi, I | 1 |
7 other studies available for fluorouracil and Leukemia, Promyelocytic, Acute
| Article | Year |
|---|---|
Design of antineoplastic agents on the basis of the "2-phenylnaphthalene-type" structural pattern. 2. Synthesis and biological activity studies of benzo]b]naphtho[2,3-d]furan-6,11-dione derivatives.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Cisplatin; DNA Topoisomerases, Type II; Furans; Humans | 1993 |
Therapy-related acute promyelocytic leukemia after chemoradiotherapy with capecitabine for rectal adenocarcinoma.
Topics: Antimetabolites, Antineoplastic; Bone Marrow; Capecitabine; Deoxycytidine; Fluorouracil; Humans; Leu | 2014 |
Acute promyelocytic leukemia in a young patient with breast cancer.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Epirubici | 2011 |
In vitro and in vivo anticancer properties of cucurbitacin isolated from Cayaponia racemosa.
Topics: Adolescent; Adult; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineopla | 2012 |
[Acute promyelocytic leukemia in a patient with colon adenocarcinoma treated with fluorouracil].
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Colonic Neoplasms; Fluorouracil; Humans; Leukemia, | 2007 |
Mechanism of interaction between interferon-gamma and antineoplastic agent on the differentiation of HL-60 promyelocytic cells.
Topics: Cell Differentiation; Cell Division; Cycloheximide; Dactinomycin; Drug Synergism; Fluorouracil; Huma | 1990 |
Heterogeneity of the response to inducers of differentiation and to cytostatics of tumor cell populations.
Topics: Antineoplastic Agents; Cell Differentiation; Cisplatin; Cytarabine; Dacarbazine; Dimethyl Sulfoxide; | 1988 |