fluorouracil has been researched along with Leptospirosis in 5 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Leptospirosis: Infections with bacteria of the genus LEPTOSPIRA.
| Excerpt | Relevance | Reference |
|---|---|---|
| ", environmental bacteria and the fungus from contaminated cultures of patients with suspected leptospirosis were inoculated into EMJH medium containing amphotericin B, 5-fluorouracil (5-FU), furazolidone and neomycin used singly or combined." | 3.88 | Evaluation of inhibitors for development of a selective medium for isolation of Leptospira spp. from clinical samples. ( Blanco, RM; Pinhata, JMW; Romero, EC, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pinhata, JMW | 1 |
| Blanco, RM | 1 |
| Romero, EC | 1 |
| JOHNSON, RC | 2 |
| ROGERS, P | 2 |
| Turner, LH | 1 |
| Myers, DM | 1 |
| Varela-Díaz, VM | 1 |
1 review available for fluorouracil and Leptospirosis
| Article | Year |
|---|---|
Leptospirosis. 3. Maintenance, isolation and demonstration of leptospires.
Topics: Agar; Animals; Blood; Cerebrospinal Fluid; Cricetinae; Culture Media; Fluorescent Antibody Technique | 1970 |
4 other studies available for fluorouracil and Leptospirosis
| Article | Year |
|---|---|
Evaluation of inhibitors for development of a selective medium for isolation of Leptospira spp. from clinical samples.
Topics: Amphotericin B; Animals; Anti-Bacterial Agents; Culture Media; Fluorouracil; Furazolidone; Humans; L | 2018 |
5-FLUOROURACIL AS A SELECTIVE AGENT FOR GROWTH OF LEPTOSPIRAE.
Topics: Animals; Carbon Isotopes; Culture Media; Dogs; Fluorouracil; Leptospira; Leptospirosis; Metabolism; | 1964 |
DIFFERENTIATION OF PATHOGENIC AND SAPROPHYTIC LEPTOSPIRES WITH 8-AZAGUANINE.
Topics: Antimetabolites; Azaguanine; Fluorouracil; Leptospira; Leptospira interrogans serovar icterohaemorrh | 1964 |
Selective isolation of leptospiras from contaminated material by incorporation of neomycin to culture media.
Topics: Animals; Cricetinae; Culture Media; Fluorouracil; Food Microbiology; Kidney; Leptospira; Leptospiros | 1973 |