fluorouracil has been researched along with Lentigo in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Lentigo: Small circumscribed melanoses resembling, but differing histologically from, freckles. The concept includes senile lentigo ('liver spots') and nevoid lentigo (nevus spilus, lentigo simplex) and may also occur in association with multiple congenital defects or congenital syndromes (e.g., Peutz-Jeghers syndrome).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three patients with biopsy-proven lentigo maligna were treated with topical 5-fluorouracil." | 7.65 | Topical chemotherapy of lentigo maligna with 5-fluorouracil. ( Krementz, ET; Litwin, MS; Mansell, PW; Reed, RJ, 1975) |
| "Three patients with biopsy-proven lentigo maligna were treated with topical 5-fluorouracil." | 3.65 | Topical chemotherapy of lentigo maligna with 5-fluorouracil. ( Krementz, ET; Litwin, MS; Mansell, PW; Reed, RJ, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katz, H | 1 |
| Redding, KG | 1 |
| Litwin, MS | 1 |
| Krementz, ET | 1 |
| Mansell, PW | 1 |
| Reed, RJ | 1 |
2 other studies available for fluorouracil and Lentigo
| Article | Year |
|---|---|
Therapeutic challenge of premalignant and malignant skin lesions.
Topics: Acetates; Adrenal Cortex Hormones; Adult; Aged; Balanitis; Bowen's Disease; Clioquinol; Cryosurgery; | 1975 |
Topical chemotherapy of lentigo maligna with 5-fluorouracil.
Topics: Aged; Evaluation Studies as Topic; Female; Fluorouracil; Follow-Up Studies; Humans; Immunity, Cellul | 1975 |