fluorouracil has been researched along with Leiomyosarcoma in 15 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Leiomyosarcoma: A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (80.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Fan, Y | 1 |
| An, JY | 1 |
| Li, NN | 1 |
| Geng, Q | 1 |
| Fu, L | 1 |
| ROCHLIN, DB | 1 |
| SMART, CR | 1 |
| SILVA, A | 1 |
| Helmkamp, BF | 1 |
| Beecham, JB | 1 |
| Wandtke, JC | 1 |
| Keys, H | 1 |
| Reich, DS | 1 |
| Palmer, CA | 1 |
| Peters, GE | 1 |
| Nagasue, N | 1 |
| Inokuchi, K | 1 |
| Kobayashi, M | 1 |
| Ogawa, Y | 1 |
| Iwaki, A | 1 |
| Black, K | 1 |
| Hanna, SS | 1 |
| Langer, B | 1 |
| Jirsch, DW | 1 |
| Rider, WD | 1 |
| Bedikian, AY | 1 |
| Valdivieso, M | 1 |
| Khankhanian, N | 1 |
| Benjamin, RS | 1 |
| Bodey, GP | 1 |
| Okada, T | 1 |
| Bergman, RB | 1 |
| Matsumoto, M | 1 |
| Goshima, H | 1 |
| Yamazaki, Y | 1 |
| Kokehara, N | 1 |
| Oota, M | 1 |
| Ishida, N | 1 |
| Itou, F | 1 |
| Hellriegel, W | 1 |
| Costanzi, JJ | 1 |
| Coltman, CA | 1 |
| Karim, F | 1 |
| Tolia, BM | 1 |
| Hajdu, SI | 1 |
| Whitmore, WF | 1 |
| Bengmark, S | 1 |
| Brix, M | 1 |
| Börjesson, B | 1 |
| Hafström, L | 1 |
| Olsson, A | 1 |
15 other studies available for fluorouracil and Leiomyosarcoma
| Article | Year |
|---|---|
[Clinicopathologic characteristics of primary breast leiomyosarcoma: report of a case].
Topics: Actins; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Calcium-Binding Pro | 2013 |
CHEMOTHERAPY OF MALIGNANCIES OF THE GASTROINTESTINAL TRACT.
Topics: Antineoplastic Agents; Carcinoid Tumor; Colonic Neoplasms; Cyclophosphamide; Fluorouracil; Gastroint | 1965 |
Spontaneous pneumothorax in gynecologic malignancies.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Cyclophosphamide; Doxorubicin; Drainage; Drug Therapy, | 1982 |
Ethmoid sinus leiomyosarcoma after cyclophosphamide treatment.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Ch | 1995 |
Hepatic dearterialization for nonrespectable primary and secondary tumors of the liver.
Topics: Adult; Aged; alpha-Fetoproteins; Carcinoma, Hepatocellular; Female; Fluorouracil; Hemangiosarcoma; H | 1976 |
Management of carcinoma of the extrahepatic bile ducts.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Bile Duct Neoplasms; Carcinoma, Squamous Cell; Child; Commo | 1978 |
Chemotherapy for sarcoma of the stomach.
Topics: Adult; Aged; Asparaginase; Cyclophosphamide; Dacarbazine; Dactinomycin; Doxorubicin; Drug Therapy, C | 1979 |
Anti-tumor activities of 1-Acetyl-3-o-Toluyl-5-Fu.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Female; Fluorouracil; HeLa Cells; Leiomyosarcoma; | 1979 |
[Experiences in the treatment of 2 patients with xeroderma pigmentosum].
Topics: Adolescent; Adult; Brain Neoplasms; Female; Fluorouracil; Humans; Leiomyosarcoma; Male; Melanoma; Ne | 1976 |
[A case of unresectable liver metastasis from leiomyosarcoma of the stomach successfully treated by intra hepato-arterial chemotherapy with Infuse-A-Port].
Topics: Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Fluorouracil; Hepatic Artery; Humans; I | 1990 |
[Esophageal tumors--therapeutic problems].
Topics: Adenocarcinoma; Bleomycin; Carcinoma; Carcinoma, Squamous Cell; Cobalt Isotopes; Esophageal Neoplasm | 1972 |
Combination chemotherapy using cyclophosphamide, vincristine, methotrexate and 5-fluorouracil in solid tumors.
Topics: Adenocarcinoma; Adult; Carcinoma, Squamous Cell; Cyclophosphamide; Female; Fibrosarcoma; Fluorouraci | 1969 |
Impressions on 5-fluorouracil in Bangladesh. Prolonged worthwhile survival in gastrointestinal malignancies.
Topics: Bangladesh; Drug Evaluation; Female; Fluorouracil; Follow-Up Studies; Gastrointestinal Hemorrhage; G | 1974 |
Leiomyosarcoma of the renal pelvis.
Topics: Female; Fluorouracil; Humans; Kidney Neoplasms; Kidney Pelvis; Leiomyosarcoma; Middle Aged; Neoplasm | 1973 |
Treatment of hepatic tumours.
Topics: Adenocarcinoma; Antineoplastic Agents; Female; Fluorouracil; Hepatic Artery; Humans; Laparotomy; Lei | 1970 |