fluorouracil has been researched along with Leg Ulcer in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Primary cutaneous mucormycosis is an opportunistic fungal infection caused by the order Mucorales, most frequently by the Rhizopus species." | 1.48 | Rapidly progressing ulcer and a urine drainage bag. ( Fernandez-Guarino, M; Jimenez-Cauhe, J; Molins-Ruiz, M, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jimenez-Cauhe, J | 1 |
| Molins-Ruiz, M | 1 |
| Fernandez-Guarino, M | 1 |
| Duncan, AL | 1 |
| Bell, HK | 1 |
2 other studies available for fluorouracil and Leg Ulcer
| Article | Year |
|---|---|
Rapidly progressing ulcer and a urine drainage bag.
Topics: Adrenal Cortex Hormones; Aged; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemothera | 2018 |
5-Fluorouracil cream and leg ulceration.
Topics: Administration, Topical; Aged; Antimetabolites, Antineoplastic; Bowen's Disease; Female; Fluorouraci | 2007 |