fluorouracil has been researched along with Leg Dermatoses in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Leg Dermatoses: A nonspecific term used to denote any cutaneous lesion or group of lesions, or eruptions of any type on the leg. (From Stedman, 25th ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Čeović, R | 1 |
| Smolković, N | 1 |
| Pašić, A | 1 |
| Kostović, K | 1 |
| Hrsan, D | 1 |
| Divers, AK | 1 |
| Correale, D | 1 |
| Lee, JB | 1 |
| Dippel, E | 1 |
| Haas, N | 1 |
| Czarnetzki, BM | 1 |
| Langer, K | 1 |
| Zonzits, E | 1 |
| Konrad, K | 1 |
1 review available for fluorouracil and Leg Dermatoses
| Article | Year |
|---|---|
Keratoacanthoma centrifugum marginatum: a diagnostic and therapeutic challenge.
Topics: Aged; Dermatologic Agents; Fluorouracil; Humans; Immunosuppressive Agents; Isotretinoin; Keratoacant | 2004 |
3 other studies available for fluorouracil and Leg Dermatoses
| Article | Year |
|---|---|
Multiple basal cell carcinomas of lower legs with stasis dermatitis: a therapeutic challenge.
Topics: Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Basal Cell; Fluorouracil; Hamartoma S | 2012 |
Porokeratosis of Mibelli associated with active chronic hepatitis and vitiligo.
Topics: Female; Fluorouracil; Hepatitis, Chronic; Humans; Leg Dermatoses; Middle Aged; Porokeratosis; Vitili | 1994 |
Hyperkeratosis lenticularis perstans (Flegel's disease). Ultrastructural study of lesional and perilesional skin and therapeutic trial of topical tretinoin versus 5-fluorouracil.
Topics: Administration, Cutaneous; Fluorouracil; Foot Dermatoses; Humans; Keratosis; Leg Dermatoses; Male; M | 1992 |