Page last updated: 2024-10-27

fluorouracil and Leanness

fluorouracil has been researched along with Leanness in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Obesity and underweight status were associated independently with inferior outcomes in patients with colon cancer who received treatment in adjuvant chemotherapy trials."2.78Body mass index at diagnosis and survival among colon cancer patients enrolled in clinical trials of adjuvant chemotherapy. ( Benson, A; Degramont, A; Foster, NR; Goldberg, RM; Labianca, R; O'Connell, MJ; Sargent, DJ; Seitz, JF; Sinicrope, FA; Yothers, G, 2013)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cihan, YB1
Sinicrope, FA1
Foster, NR1
Yothers, G1
Benson, A1
Seitz, JF1
Labianca, R1
Goldberg, RM1
Degramont, A1
O'Connell, MJ1
Sargent, DJ1

Trials

1 trial available for fluorouracil and Leanness

ArticleYear
Body mass index at diagnosis and survival among colon cancer patients enrolled in clinical trials of adjuvant chemotherapy.
    Cancer, 2013, Apr-15, Volume: 119, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Chemotherapy, Adjuvant; Colonic Neo

2013

Other Studies

1 other study available for fluorouracil and Leanness

ArticleYear
Relationship of body mass index with prognosis in breast cancer patients treated with adjuvant radiotherapy and chemotherapy.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol

2014