fluorouracil has been researched along with Leanness in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Obesity and underweight status were associated independently with inferior outcomes in patients with colon cancer who received treatment in adjuvant chemotherapy trials." | 2.78 | Body mass index at diagnosis and survival among colon cancer patients enrolled in clinical trials of adjuvant chemotherapy. ( Benson, A; Degramont, A; Foster, NR; Goldberg, RM; Labianca, R; O'Connell, MJ; Sargent, DJ; Seitz, JF; Sinicrope, FA; Yothers, G, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cihan, YB | 1 |
| Sinicrope, FA | 1 |
| Foster, NR | 1 |
| Yothers, G | 1 |
| Benson, A | 1 |
| Seitz, JF | 1 |
| Labianca, R | 1 |
| Goldberg, RM | 1 |
| Degramont, A | 1 |
| O'Connell, MJ | 1 |
| Sargent, DJ | 1 |
1 trial available for fluorouracil and Leanness
| Article | Year |
|---|---|
Body mass index at diagnosis and survival among colon cancer patients enrolled in clinical trials of adjuvant chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Chemotherapy, Adjuvant; Colonic Neo | 2013 |
1 other study available for fluorouracil and Leanness
| Article | Year |
|---|---|
Relationship of body mass index with prognosis in breast cancer patients treated with adjuvant radiotherapy and chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocol | 2014 |