fluorouracil has been researched along with Labyrinthitis in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Labyrinthitis: Inflammation of the inner ear (LABYRINTH).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Systemic immunosuppressives are used to treat sensorineural hearing loss due to inflammation (autoimmune, bacterial, viral), which in animal models causes hearing loss." | 1.31 | Intratympanic immunosuppressives for prevention of immune-mediated sensorineural hearing loss. ( Harris, JP; Keithley, EM; Song, HT; Yang, GS, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, GS | 1 |
| Song, HT | 1 |
| Keithley, EM | 1 |
| Harris, JP | 1 |
1 other study available for fluorouracil and Labyrinthitis
| Article | Year |
|---|---|
Intratympanic immunosuppressives for prevention of immune-mediated sensorineural hearing loss.
Topics: Animals; Anti-Inflammatory Agents; Cyclosporine; Dexamethasone; Disease Models, Animal; Drug Evaluat | 2000 |