fluorouracil has been researched along with Klebsiella Infections in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Klebsiella Infections: Infections with bacteria of the genus KLEBSIELLA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Subsequent dosing with 5-FU induced lethal septicaemia caused by the inoculated strains in most of these mice, whereas CY did not regularly induce septicaemia." | 1.29 | Experimental endogenous septicaemia caused by Klebsiella pneumoniae and Escherichia coli in mice. ( Furuya, N; Hirakata, Y; Matsumoto, T; Tateda, K; Yamaguchi, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hirakata, Y | 1 |
| Furuya, N | 1 |
| Matsumoto, T | 1 |
| Tateda, K | 1 |
| Yamaguchi, K | 1 |
1 other study available for fluorouracil and Klebsiella Infections
| Article | Year |
|---|---|
Experimental endogenous septicaemia caused by Klebsiella pneumoniae and Escherichia coli in mice.
Topics: Ampicillin; Animals; Bacteremia; Ceftazidime; Cephalosporins; Cyclophosphamide; Disease Models, Anim | 1996 |