fluorouracil has been researched along with Klatskin Tumor in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Klatskin Tumor: Cholangiocarcinoma arising near or at the confluence of the right and left hepatic ducts (COMMON HEPATIC DUCT). These tumors are generally small, sharply localized, and seldom metastasizing.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bisello, S | 1 |
| Buwenge, M | 1 |
| Palloni, A | 1 |
| Autorino, R | 1 |
| Cellini, F | 1 |
| Macchia, G | 1 |
| Deodato, F | 1 |
| Cilla, S | 1 |
| Brandi, G | 1 |
| Tagliaferri, L | 1 |
| Cammelli, S | 1 |
| Valentini, V | 1 |
| Morganti, AG | 1 |
| Mattiucci, GC | 1 |
| Chen, Y | 1 |
| Li, H | 1 |
| Jiang, X | 1 |
| Chen, D | 1 |
| Ni, J | 1 |
| Sun, H | 1 |
| Luo, J | 1 |
| Yao, H | 1 |
| Xu, L | 1 |
| Schleicher, UM | 1 |
| Staatz, G | 1 |
| Alzen, G | 1 |
| Andreopoulos, D | 1 |
3 other studies available for fluorouracil and Klatskin Tumor
| Article | Year |
|---|---|
Radiotherapy or Chemoradiation in Unresectable Biliary Cancer: A Retrospective Study.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Bile Duct Neoplasms; Brachytherapy; | 2019 |
Regional thermochemotherapy versus hepatic arterial infusion chemotherapy for palliative treatment of advanced hilar cholangiocarcinoma: a retrospective controlled study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Duct Neoplasms; Cisplatin; Combine | 2016 |
Combined external beam and intraluminal radiotherapy for irresectable Klatskin tumors.
Topics: Aged; Aged, 80 and over; Bile Duct Neoplasms; Brachytherapy; Chemotherapy, Adjuvant; Combined Modali | 2002 |