fluorouracil and Keratosis Seborrheica studies

fluorouracil and Keratosis Seborrheica

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

Excerpt	Relevance	Reference
"Leser-Trélat-syndrome is characterized as the eruptive appearance of multiple seborrheic keratoses in association with underlying malignant disease."	1.31	[Clinical and histopathological characteristics of early Leser-Trélat syndrome]. ( Barth, G; Basten, O; Rompel, R; Rüschoff, J, 2001)
"Giant seborrheic keratosis was observed on the frontal scalp of a 44-year-old man."	1.29	Giant seborrheic keratosis on the frontal scalp treated with topical fluorouracil. ( Morita, A; Tsuji, T, 1995)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	1 (33.33)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

1 (33.33)

18.2507

2000's

1 (33.33)

29.6817

2010's

1 (33.33)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Goodhead, C	1
Hampton, P	1
Tsuji, T	1
Morita, A	1
Barth, G	1
Basten, O	1
Rüschoff, J	1
Rompel, R	1

Studies

Goodhead, C

Hampton, P

Tsuji, T

Morita, A

Barth, G

Basten, O

Rüschoff, J

Rompel, R

Other Studies

3 other studies available for fluorouracil and Keratosis Seborrheica

Article	Year
Actikerall: an alternative to curettage for some seborrhoeic keratoses? Clinical and experimental dermatology, 2018, Volume: 43, Issue:2 Topics: Aged; Antimetabolites; Drug Combinations; Fluorouracil; Humans; Keratolytic Agents; Keratosis, Sebor	2018
Giant seborrheic keratosis on the frontal scalp treated with topical fluorouracil. The Journal of dermatology, 1995, Volume: 22, Issue:1 Topics: Administration, Cutaneous; Adult; Fluorouracil; Gentamicins; Humans; Keratosis, Seborrheic; Male; Oc	1995
[Clinical and histopathological characteristics of early Leser-Trélat syndrome]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2001, Volume: 52, Issue:7 Topics: Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Colon; Colonic Neoplasms; Colonosco	2001

Article

Year

Actikerall: an alternative to curettage for some seborrhoeic keratoses?

Clinical and experimental dermatology, 2018, Volume: 43, Issue:2

Topics: Aged; Antimetabolites; Drug Combinations; Fluorouracil; Humans; Keratolytic Agents; Keratosis, Sebor

2018

Giant seborrheic keratosis on the frontal scalp treated with topical fluorouracil.

The Journal of dermatology, 1995, Volume: 22, Issue:1

Topics: Administration, Cutaneous; Adult; Fluorouracil; Gentamicins; Humans; Keratosis, Seborrheic; Male; Oc

1995

[Clinical and histopathological characteristics of early Leser-Trélat syndrome].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2001, Volume: 52, Issue:7

Topics: Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Colon; Colonic Neoplasms; Colonosco

2001