fluorouracil has been researched along with Keratosis, Seborrheic in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Keratosis, Seborrheic: Benign eccrine poromas that present as multiple oval, brown-to-black plaques, located mostly on the chest and back. The age of onset is usually in the fourth or fifth decade.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leser-Trélat-syndrome is characterized as the eruptive appearance of multiple seborrheic keratoses in association with underlying malignant disease." | 1.31 | [Clinical and histopathological characteristics of early Leser-Trélat syndrome]. ( Barth, G; Basten, O; Rompel, R; Rüschoff, J, 2001) |
| "Giant seborrheic keratosis was observed on the frontal scalp of a 44-year-old man." | 1.29 | Giant seborrheic keratosis on the frontal scalp treated with topical fluorouracil. ( Morita, A; Tsuji, T, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goodhead, C | 1 |
| Hampton, P | 1 |
| Tsuji, T | 1 |
| Morita, A | 1 |
| Barth, G | 1 |
| Basten, O | 1 |
| Rüschoff, J | 1 |
| Rompel, R | 1 |
3 other studies available for fluorouracil and Keratosis, Seborrheic
| Article | Year |
|---|---|
Actikerall: an alternative to curettage for some seborrhoeic keratoses?
Topics: Aged; Antimetabolites; Drug Combinations; Fluorouracil; Humans; Keratolytic Agents; Keratosis, Sebor | 2018 |
Giant seborrheic keratosis on the frontal scalp treated with topical fluorouracil.
Topics: Administration, Cutaneous; Adult; Fluorouracil; Gentamicins; Humans; Keratosis, Seborrheic; Male; Oc | 1995 |
[Clinical and histopathological characteristics of early Leser-Trélat syndrome].
Topics: Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Colon; Colonic Neoplasms; Colonosco | 2001 |