fluorouracil has been researched along with Keratoderma, Palmoplantar, Diffuse in 2 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Keratoderma, Palmoplantar, Diffuse: An autosomal dominant disorder characterized by a widely distributed, well-demarcated hyperkeratosis of the palms and soles. There is more than one genotypically distinct form, each of which is clinically similar but histologically distinguishable. Diffuse palmoplantar keratoderma is distinct from palmoplantar keratoderma (KERATODERMA, PALMOPLANTAR), as the former exhibits autosomal dominant inheritance and hyperhidrosis is frequently present.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walsh, SN | 1 |
| Bell, RC | 1 |
| Osman, Y | 1 |
| Daly, TJ | 1 |
| Don, PC | 1 |
2 other studies available for fluorouracil and Keratoderma, Palmoplantar, Diffuse
| Article | Year |
|---|---|
Spiny projections on the palms and soles. Spiny keratoderma of the palms and soles.
Topics: Administration, Topical; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Debrideme | 2010 |
Spiny keratoderma of the palms and soles.
Topics: Aged; Diagnosis, Differential; Female; Fluorouracil; Humans; Keratoderma, Palmoplantar; Keratoderma, | 1992 |