fluorouracil has been researched along with Keratocysts in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An innovation in the treatment of odontogenic keratocysts (OKCs) is the adjunctive application of 5-fluorouracil (5-FU)." | 8.31 | Refined Topical 5-Fluorouracil Technique for the Targeted Treatment of Odontogenic Keratocysts. ( Casino, AJ; Lam, DK; LeRoy, J; Reddy, R, 2023) |
| "An innovation in the treatment of odontogenic keratocysts (OKCs) is the adjunctive application of 5-fluorouracil (5-FU)." | 4.31 | Refined Topical 5-Fluorouracil Technique for the Targeted Treatment of Odontogenic Keratocysts. ( Casino, AJ; Lam, DK; LeRoy, J; Reddy, R, 2023) |
| "The antimetabolite drug, 5-fluorouracil (5-FU), has been suggested as an adjunctive treatment to reduce the recurrence rates of odontogenic keratocysts (OKCs)." | 4.02 | 5-Fluorouracil Is Associated With a Decreased Recurrence Risk in Odontogenic Keratocyst Management: A Retrospective Cohort Study. ( Bradley, G; Caminiti, MF; El-Rabbany, M; Jeon, J, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 6 (85.71) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, AK | 1 |
| Khanal, N | 1 |
| Chaulagain, R | 1 |
| Bhujel, N | 1 |
| Singh, RP | 1 |
| Al-Moraissi, EA | 1 |
| Kaur, A | 1 |
| Gomez, RS | 1 |
| Ellis, E | 1 |
| Casino, AJ | 1 |
| LeRoy, J | 1 |
| Reddy, R | 1 |
| Lam, DK | 2 |
| Caminiti, MF | 3 |
| El-Rabbany, M | 1 |
| Jeon, J | 1 |
| Bradley, G | 2 |
| Morgan, S | 1 |
| Schlieve, T | 1 |
| Ledderhof, NJ | 1 |
2 reviews available for fluorouracil and Keratocysts
| Article | Year |
|---|---|
How effective is 5-Fluorouracil as an adjuvant in the management of odontogenic keratocyst? A systematic review and meta-analysis.
Topics: Adjuvants, Immunologic; Fluorouracil; Humans; Odontogenic Cysts; Odontogenic Tumors; Paresthesia | 2022 |
Effectiveness of different treatments for odontogenic keratocyst: a network meta-analysis.
Topics: Fluorouracil; Humans; Network Meta-Analysis; Odontogenic Cysts; Odontogenic Tumors; Retrospective St | 2023 |
5 other studies available for fluorouracil and Keratocysts
| Article | Year |
|---|---|
Refined Topical 5-Fluorouracil Technique for the Targeted Treatment of Odontogenic Keratocysts.
Topics: Female; Fluorouracil; Humans; Male; Odontogenic Cysts; Odontogenic Tumors; Retrospective Studies; Tr | 2023 |
5-Fluorouracil Is Associated With a Decreased Recurrence Risk in Odontogenic Keratocyst Management: A Retrospective Cohort Study.
Topics: Fluorouracil; Humans; Neoplasm Recurrence, Local; Odontogenic Cysts; Odontogenic Tumors; Recurrence; | 2021 |
Author Commentary on Article - 5-Fluorouracil Is Associated With a Decreased Recurrence Risk in Odontogenic Keratocyst Management: A Retrospective Cohort Study.
Topics: Fluorouracil; Humans; Odontogenic Cysts; Odontogenic Tumors; Retrospective Studies | 2021 |
Review of 5-Fluorouracil is Associated With a Decreased Recurrence Risk in Odontogenic Keratocyst Management: A Retrospective Cohort Study.
Topics: Fluorouracil; Humans; Odontogenic Cysts; Odontogenic Tumors; Retrospective Studies | 2021 |
Topical 5-Fluorouracil is a Novel Targeted Therapy for the Keratocystic Odontogenic Tumor.
Topics: Administration, Topical; Adult; Antimetabolites, Antineoplastic; Combined Modality Therapy; Dihydrou | 2017 |