fluorouracil has been researched along with Kaposi Disease in 19 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This case report describes treatment regimens with topical calcipotriol plus fluorouracil for 2 patients with xeroderma pigmentosum." | 8.31 | Prevention of Skin Cancers With Topical Calcipotriol and Fluorouracil in Patients With Xeroderma Pigmentosum. ( Demehri, S; Gill, JG; Kim, J; Savory, SA, 2023) |
| "This case report describes treatment regimens with topical calcipotriol plus fluorouracil for 2 patients with xeroderma pigmentosum." | 4.31 | Prevention of Skin Cancers With Topical Calcipotriol and Fluorouracil in Patients With Xeroderma Pigmentosum. ( Demehri, S; Gill, JG; Kim, J; Savory, SA, 2023) |
| "to evaluate the feasibility, tolerance/toxicity and therapeutic efficacy of 5-fluorouracil (5-FU) by topical application and systemic use, in facial carcinoma associated with XP." | 3.73 | [Topical and systemic chemotherapy with 5-fluouracil in facial carcinoma secondary to xeroderma pigmentosum]. ( Boussen, H; Boussen, I; Ferjaoui, M; Gritli, S; Khader, A; Ladgham, A; Nouira, R; Oueslati, Z, 2005) |
| "Tumour histology was squamous cell carcinoma in 74% of the cases." | 1.37 | [Radiotherapy for cutaneous cancers with xeroderma pigmentosum]. ( Abdelmoula, M; Bahri, M; Ben Salah, H; Daoud, J; Frikha, M; Turki, H, 2011) |
| "Four patients with Xeroderma pigmentosum are reported: 2 diagnosed following the development of multiple cutaneous tumours, and 2 at an earlier state." | 1.26 | Xeroderma pigmentosum--biochemical and therapeutic aspects. Case report. ( Bartholdson, L; Lija, J; Mobacken, H; Waldenström, J, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (68.42) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, J | 1 |
| Savory, SA | 1 |
| Demehri, S | 1 |
| Gill, JG | 1 |
| Schulze Schwering, M | 1 |
| Schwering, MS | 1 |
| Chagaluka, G | 1 |
| Molyneux, E | 1 |
| Ben Salah, H | 1 |
| Bahri, M | 1 |
| Turki, H | 1 |
| Abdelmoula, M | 1 |
| Frikha, M | 1 |
| Daoud, J | 1 |
| Khader, A | 1 |
| Gritli, S | 1 |
| Boussen, I | 1 |
| Oueslati, Z | 1 |
| Ferjaoui, M | 1 |
| Nouira, R | 1 |
| Ladgham, A | 1 |
| Boussen, H | 1 |
| Casson, P | 1 |
| Saade, M | 1 |
| Debahy, NE | 1 |
| Houjeily, S | 1 |
| Hamouda, B | 1 |
| Jamila, Z | 1 |
| Najet, R | 1 |
| Slim, T | 1 |
| Rafiaa, N | 1 |
| Noureddine, B | 1 |
| Ahmed, EM | 1 |
| Mohamed, F | 1 |
| Ridha, KM | 1 |
| Abderrahman, L | 1 |
| Bartholdson, L | 1 |
| Lija, J | 1 |
| Mobacken, H | 1 |
| Waldenström, J | 1 |
| Bergman, RB | 1 |
| Salamon, T | 1 |
| Stojaković, M | 1 |
| Bogdanović, B | 1 |
| Diem, E | 1 |
| Fritsch, P | 1 |
| Swart-Bruinsma, WA | 1 |
| Herrmann, WA | 1 |
| Gleason, MC | 1 |
| Zeligman, I | 1 |
| Lutzner, MA | 1 |
| Scott, CI | 1 |
| Garcia-Perez, A | 1 |
| Aparicio, M | 1 |
| Carapeto, FJ | 1 |
| De Moragas, JM | 1 |
| Gimenez-Camarasa, JM | 1 |
| Midana, A | 1 |
| Leigheb, G | 1 |
| Carter, VH | 1 |
| Smith, KW | 1 |
| Noojin, RO | 1 |
19 other studies available for fluorouracil and Kaposi Disease
| Article | Year |
|---|---|
Prevention of Skin Cancers With Topical Calcipotriol and Fluorouracil in Patients With Xeroderma Pigmentosum.
Topics: Calcitriol; Fluorouracil; Humans; Skin Neoplasms; Xeroderma Pigmentosum | 2023 |
Treatment of cancer in a child with ocular xeroderma pigmentosa (XP) in Malawi.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Child, Preschool; | 2014 |
[Radiotherapy for cutaneous cancers with xeroderma pigmentosum].
Topics: Adolescent; Adult; Age of Onset; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brachyth | 2011 |
[Topical and systemic chemotherapy with 5-fluouracil in facial carcinoma secondary to xeroderma pigmentosum].
Topics: Administration, Cutaneous; Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents | 2005 |
Basal cell carcinoma.
Topics: Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Cryosurgery; Female; Fluorouracil; Humans; Male; N | 1980 |
Clinical remission of xeroderma pigmentosum-associated squamous cell carcinoma with isotretinoin and chemotherapy: case report.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Child; Cisplatin; Fluorour | 1999 |
Topical 5-fluorouracil to treat multiple or unresectable facial squamous cell carcinomas in xeroderma pigmentosum.
Topics: Administration, Topical; Adolescent; Adult; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cel | 2001 |
Xeroderma pigmentosum--biochemical and therapeutic aspects. Case report.
Topics: 4-Aminobenzoic Acid; Administration, Topical; Adult; Aminobenzoates; Child; DNA Repair; Female; Fluo | 1977 |
[Experiences in the treatment of 2 patients with xeroderma pigmentosum].
Topics: Adolescent; Adult; Brain Neoplasms; Female; Fluorouracil; Humans; Leiomyosarcoma; Male; Melanoma; Ne | 1976 |
Delayed hypersensitivity in xeroderma pigmentosum.
Topics: Carcinoma, Squamous Cell; Child; Child, Preschool; Eye Diseases; Female; Fluorouracil; Humans; Hyper | 1975 |
[Xeroderma pigmentosum, universal alopecia and associated neuro-ocular symptoms].
Topics: Administration, Topical; Alopecia; Brain Diseases; Fluorouracil; Glaucoma; Humans; Male; Middle Aged | 1973 |
Fluorouracil cream (Efudix) in dermatology.
Topics: Fluorouracil; Humans; Keratosis; Psoriasis; Skin Diseases; Skin Neoplasms; Xeroderma Pigmentosum | 1973 |
[External treatment with 5-fluorouracil].
Topics: Carcinoma, Squamous Cell; Fluorouracil; Humans; Keratoacanthoma; Keratosis; Ointments; Xeroderma Pig | 1973 |
Xeroderma pigmentosum--five-year arrest after total resurfacing of the face.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Child, Preschool; Dermabrasion; Electrosurgery; Fac | 1970 |
Xeroderma pigmentosum.
Topics: Adult; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Child, Preschool; Eyelid Neoplasms; Female; | 1971 |
Comparison of the clinical and histological effects of 5-fluorouracil (5-FU) alone and of 5-FU preceded by dimethyl-sulphoxide (DMSO) on senile keratosis.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dimethyl Sulfoxide; Fluorouracil; Humans; Keratosis | 1970 |
5-fluorouracil ointment in tumors of the skin.
Topics: Aged; Carcinoma, Basal Cell; Female; Fluorouracil; Humans; Keratoacanthoma; Keratosis; Male; Middle | 1970 |
5-fluorouracil (5-FU) ointment in the treatment of benign and malignant skin lesions.
Topics: Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Fluorouracil; Humans; Keratoacanthoma; Keratosis; L | 1970 |
Xeroderma pigmentosum. Treatment with topically applied fluorouracil.
Topics: Adolescent; Adult; Carcinoma, Squamous Cell; Female; Fluorouracil; Humans; Keratosis; Skin Neoplasms | 1968 |