fluorouracil has been researched along with Jaw Diseases in 7 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Jaw Diseases: Diseases involving the JAW.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antiangiogenic monoclonal antibody aflibercept in association with fluorouracil and irinotecan improves the survival of patients with metastatic colorectal cancer (mCRC) treated previously with oxaliplatin-based therapy." | 8.93 | Jaw osteonecrosis associated with aflibercept, irinotecan and fluorouracil: attention to oral district. ( Ciuffreda, L; Fanchini, L; Mecca, C; Pinta, F; Ponzetti, A; Racca, P; Spadi, R; Zanini, M, 2016) |
| "The antiangiogenic monoclonal antibody aflibercept in association with fluorouracil and irinotecan improves the survival of patients with metastatic colorectal cancer (mCRC) treated previously with oxaliplatin-based therapy." | 4.93 | Jaw osteonecrosis associated with aflibercept, irinotecan and fluorouracil: attention to oral district. ( Ciuffreda, L; Fanchini, L; Mecca, C; Pinta, F; Ponzetti, A; Racca, P; Spadi, R; Zanini, M, 2016) |
| "The pathogenesis and treatment of osteonecrosis have not been elucidated." | 1.39 | [A case of osteonecrosis of the jaw during treatment by bevacizumab for sigmoid colon cancer]. ( Ono, F; Onochi, S; Sato, M; Yamamura, A, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sato, M | 1 |
| Ono, F | 1 |
| Yamamura, A | 1 |
| Onochi, S | 1 |
| Ponzetti, A | 1 |
| Pinta, F | 1 |
| Spadi, R | 1 |
| Mecca, C | 1 |
| Fanchini, L | 1 |
| Zanini, M | 1 |
| Ciuffreda, L | 1 |
| Racca, P | 1 |
| Gataa, IS | 1 |
| Nader, NH | 1 |
| Abdallah, DT | 1 |
| Labandter, HP | 1 |
| Ryan, RF | 1 |
| Habal, MB | 1 |
| Biano, G | 1 |
| Cavins, JA | 1 |
| Boileau, GA | 1 |
| Klein, E | 1 |
| Murray, JE | 1 |
| Moynahan, EJ | 1 |
| Watt, TL | 1 |
| Bragg, FE | 1 |
2 reviews available for fluorouracil and Jaw Diseases
| Article | Year |
|---|---|
Jaw osteonecrosis associated with aflibercept, irinotecan and fluorouracil: attention to oral district.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cam | 2016 |
Massive Craniofacial Gorham Disease Treated Successfully by Cisplatin and 5-Fluorouracil With Ten Years of Follow-Up: A Case Report and Literature Review.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cisplatin; Female; Fluorouracil; | 2016 |
5 other studies available for fluorouracil and Jaw Diseases
| Article | Year |
|---|---|
[A case of osteonecrosis of the jaw during treatment by bevacizumab for sigmoid colon cancer].
Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemothera | 2013 |
5-fluorouracil in Gorlin's syndrome.
Topics: Aged; Carcinoma, Basal Cell; Female; Fluorouracil; Humans; Jaw Diseases; Skin Neoplasms; Syndrome | 1978 |
The "turban" nevoid basal cell syndrome. Current management with surgery, chemotherapy and immunotherapy.
Topics: Adult; Bone Cysts; Carcinoma, Basal Cell; Dinitrochlorobenzene; Fluorouracil; Humans; Jaw Diseases; | 1975 |
Multiple basal cell naevus syndrome--successful treatment of basal cell tumours with 5-fluorouracil.
Topics: Adult; Carcinoma, Basal Cell; Dentigerous Cyst; Fluorouracil; Humans; Jaw Diseases; Male; Skin Neopl | 1973 |
Additional observations on the nevoid basal cell epithelioma syndrome. A case report.
Topics: Adolescent; Carcinoma, Basal Cell; Cysts; Fluorouracil; Humans; Jaw Abnormalities; Jaw Diseases; Jaw | 1973 |