Page last updated: 2024-10-27

fluorouracil and Jaw Diseases

fluorouracil has been researched along with Jaw Diseases in 7 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Jaw Diseases: Diseases involving the JAW.

Research Excerpts

ExcerptRelevanceReference
"The antiangiogenic monoclonal antibody aflibercept in association with fluorouracil and irinotecan improves the survival of patients with metastatic colorectal cancer (mCRC) treated previously with oxaliplatin-based therapy."8.93Jaw osteonecrosis associated with aflibercept, irinotecan and fluorouracil: attention to oral district. ( Ciuffreda, L; Fanchini, L; Mecca, C; Pinta, F; Ponzetti, A; Racca, P; Spadi, R; Zanini, M, 2016)
"The antiangiogenic monoclonal antibody aflibercept in association with fluorouracil and irinotecan improves the survival of patients with metastatic colorectal cancer (mCRC) treated previously with oxaliplatin-based therapy."4.93Jaw osteonecrosis associated with aflibercept, irinotecan and fluorouracil: attention to oral district. ( Ciuffreda, L; Fanchini, L; Mecca, C; Pinta, F; Ponzetti, A; Racca, P; Spadi, R; Zanini, M, 2016)
"The pathogenesis and treatment of osteonecrosis have not been elucidated."1.39[A case of osteonecrosis of the jaw during treatment by bevacizumab for sigmoid colon cancer]. ( Ono, F; Onochi, S; Sato, M; Yamamura, A, 2013)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sato, M1
Ono, F1
Yamamura, A1
Onochi, S1
Ponzetti, A1
Pinta, F1
Spadi, R1
Mecca, C1
Fanchini, L1
Zanini, M1
Ciuffreda, L1
Racca, P1
Gataa, IS1
Nader, NH1
Abdallah, DT1
Labandter, HP1
Ryan, RF1
Habal, MB1
Biano, G1
Cavins, JA1
Boileau, GA1
Klein, E1
Murray, JE1
Moynahan, EJ1
Watt, TL1
Bragg, FE1

Reviews

2 reviews available for fluorouracil and Jaw Diseases

ArticleYear
Jaw osteonecrosis associated with aflibercept, irinotecan and fluorouracil: attention to oral district.
    Tumori, 2016, Nov-11, Volume: 102, Issue:Suppl. 2

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cam

2016
Massive Craniofacial Gorham Disease Treated Successfully by Cisplatin and 5-Fluorouracil With Ten Years of Follow-Up: A Case Report and Literature Review.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2016, Volume: 74, Issue:9

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cisplatin; Female; Fluorouracil;

2016

Other Studies

5 other studies available for fluorouracil and Jaw Diseases

ArticleYear
[A case of osteonecrosis of the jaw during treatment by bevacizumab for sigmoid colon cancer].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2013, Volume: 110, Issue:4

    Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemothera

2013
5-fluorouracil in Gorlin's syndrome.
    The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1978, Volume: 130, Issue:4

    Topics: Aged; Carcinoma, Basal Cell; Female; Fluorouracil; Humans; Jaw Diseases; Skin Neoplasms; Syndrome

1978
The "turban" nevoid basal cell syndrome. Current management with surgery, chemotherapy and immunotherapy.
    International surgery, 1975, Volume: 60, Issue:9

    Topics: Adult; Bone Cysts; Carcinoma, Basal Cell; Dinitrochlorobenzene; Fluorouracil; Humans; Jaw Diseases;

1975
Multiple basal cell naevus syndrome--successful treatment of basal cell tumours with 5-fluorouracil.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:7

    Topics: Adult; Carcinoma, Basal Cell; Dentigerous Cyst; Fluorouracil; Humans; Jaw Diseases; Male; Skin Neopl

1973
Additional observations on the nevoid basal cell epithelioma syndrome. A case report.
    The Journal of the Maine Medical Association, 1973, Volume: 64, Issue:12

    Topics: Adolescent; Carcinoma, Basal Cell; Cysts; Fluorouracil; Humans; Jaw Abnormalities; Jaw Diseases; Jaw

1973