fluorouracil has been researched along with Jaundice in 17 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the effect of 5-fluorouracil (5-FU) and folinic acid on liver function and bile production in patients with recurrent gastric cancer and jaundice." | 7.69 | Relief of jaundice by 5-fluorouracil and folinic acid in patients with recurrent gastric cancer. ( Akiyama, H; Kajiyama, Y; Kinoshita, Y; Tsurumaru, M; Tsutsumi, K; Udagawa, H, 1996) |
| " Decreases in the rates of ascites and jaundice were confirmed by ultrasound and bilirubin levels." | 3.80 | Whole-liver radiotherapy concurrent with chemotherapy as a palliative treatment for colorectal patients with massive and multiple liver metastases: a retrospective study. ( Lu, K; Qiao, WB; Sun, D; Yin, H; You, QS; Zhang, HY, 2014) |
| "The aim of this study was to evaluate the effect of 5-fluorouracil (5-FU) and folinic acid on liver function and bile production in patients with recurrent gastric cancer and jaundice." | 3.69 | Relief of jaundice by 5-fluorouracil and folinic acid in patients with recurrent gastric cancer. ( Akiyama, H; Kajiyama, Y; Kinoshita, Y; Tsurumaru, M; Tsutsumi, K; Udagawa, H, 1996) |
| " We started combination chemotherapy with 5-fluorouracil, Leucovorin and oxaliplatin(modified FOLFOX6)at a 20% lower than standard dosage for safety." | 2.49 | [A case of metastatic colorectal cancer with icterus due to multiple liver metastases treated effectively by FOLFOX plus bevacizumab]. ( Fukuda, K; Koja, S; Terasawa, T; Yasuda, K, 2013) |
| "The prognosis of patients with advanced colorectal cancer with icterus is dismally poor, and adequate chemotherapy for these patients has not been established yet." | 1.37 | FOLFOX plus cetuximab for a patient with metastatic colorectal cancer with icterus due to multiple liver metastases. ( Kondo, C; Mizota, A; Muro, K; Nomura, M; Shitara, K; Takahari, D; Ura, T; Yokota, T, 2011) |
| "Most nonendocrine pancreatic neoplasms are adenocarcinomas of ductal cell or acinar origin." | 1.31 | Squamous cell carcinoma of the pancreas with cystic degeneration. ( Colarian, J; Fowler, D; Poolos, S; Schor, J, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (47.06) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vienot, A | 1 |
| Beinse, G | 1 |
| Louvet, C | 1 |
| de Mestier, L | 1 |
| Meurisse, A | 1 |
| Fein, F | 1 |
| Heyd, B | 1 |
| Cleau, D | 1 |
| d'Engremont, C | 1 |
| Dupont-Gossart, AC | 1 |
| Lakkis, Z | 1 |
| Tournigand, C | 1 |
| Bouché, O | 1 |
| Rousseau, B | 1 |
| Neuzillet, C | 1 |
| Bonnetain, F | 1 |
| Borg, C | 1 |
| Vernerey, D | 1 |
| Umemura, K | 1 |
| Miura, T | 1 |
| Ishido, K | 1 |
| Sakamoto, Y | 1 |
| Kudo, D | 1 |
| Kimura, N | 1 |
| Morohashi, H | 1 |
| Hakamada, K | 1 |
| Terasawa, T | 1 |
| Koja, S | 1 |
| Yasuda, K | 1 |
| Fukuda, K | 1 |
| Yin, H | 1 |
| Lu, K | 1 |
| Qiao, WB | 1 |
| Zhang, HY | 1 |
| Sun, D | 1 |
| You, QS | 1 |
| Mizota, A | 1 |
| Shitara, K | 1 |
| Kondo, C | 1 |
| Nomura, M | 1 |
| Yokota, T | 1 |
| Takahari, D | 1 |
| Ura, T | 1 |
| Muro, K | 1 |
| Nabeshima, S | 1 |
| Kishihara, Y | 1 |
| Nabeshima, A | 1 |
| Yamaga, S | 1 |
| Kinjo, M | 1 |
| Kashiwagi, S | 1 |
| Hayashi, J | 1 |
| Uchida, S | 1 |
| Nokita, H | 1 |
| Horiuchi, H | 1 |
| Hisaka, T | 1 |
| Ishikawa, H | 1 |
| Kawashima, Y | 1 |
| Fujishita, M | 1 |
| Kinoshita, H | 1 |
| Aoyagi, S | 1 |
| Shirouzu, K | 1 |
| Hornowski, S | 1 |
| Olkowski, L | 1 |
| Hashmonai, M | 1 |
| Lev, L | 1 |
| Schramek, A | 1 |
| Ben-Arieh, Y | 1 |
| Robinson, E | 1 |
| Kajiyama, Y | 1 |
| Tsurumaru, M | 1 |
| Udagawa, H | 1 |
| Tsutsumi, K | 1 |
| Kinoshita, Y | 1 |
| Akiyama, H | 1 |
| Colarian, J | 1 |
| Fowler, D | 1 |
| Schor, J | 1 |
| Poolos, S | 1 |
| Ingis, DA | 1 |
| Farmer, RG | 1 |
| Foitl, DR | 1 |
| Hyman, G | 1 |
| Lefkowitch, JH | 1 |
| Humphrey, LJ | 1 |
| Gazet, JC | 1 |
| Smith, R | 1 |
| Priestman, TJ | 1 |
| Hanham, IW | 1 |
| Hughes, J | 1 |
| Stoker, TA | 1 |
1 review available for fluorouracil and Jaundice
| Article | Year |
|---|---|
[A case of metastatic colorectal cancer with icterus due to multiple liver metastases treated effectively by FOLFOX plus bevacizumab].
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Fata | 2013 |
16 other studies available for fluorouracil and Jaundice
| Article | Year |
|---|---|
Overall Survival Prediction and Usefulness of Second-Line Chemotherapy in Advanced Pancreatic Adenocarcinoma.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Ascites; Camptothecin; Cancer Pai | 2017 |
[A Case of Complete Pathological Response of Unresectable Synchronous Colorectal Hepatic Metastasis with Icterus after FOLFOX plus Panitumumab Therapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Hepatecto | 2018 |
Whole-liver radiotherapy concurrent with chemotherapy as a palliative treatment for colorectal patients with massive and multiple liver metastases: a retrospective study.
Topics: Aged; Antimetabolites, Antineoplastic; Ascites; Bilirubin; Colorectal Neoplasms; Combined Modality T | 2014 |
FOLFOX plus cetuximab for a patient with metastatic colorectal cancer with icterus due to multiple liver metastases.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Prot | 2011 |
Poorly differentiated adenocarcinoma with signet-ring cells of the Vater's ampulla, without jaundice but with disseminated carcinomatosis.
Topics: Ampulla of Vater; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Carcinoma, | 2003 |
[The hepatic artery injection chemotherapy and prostaglandin E1 administration for hepatocellular carcinoma invading the biliary tract with jaundice].
Topics: Aged; Alprostadil; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; | 2005 |
[A case of jaundice caused by 5-fluorouracil].
Topics: Fluorouracil; Humans; Jaundice; Male; Middle Aged; Postoperative Complications; Stomach Neoplasms | 1967 |
Long survival following combined treatment of inoperable cholangiocarcinoma: surgery, radiotherapy, and chemotherapy.
Topics: Adenoma, Bile Duct; Bile Duct Neoplasms; Cobalt Radioisotopes; Cyclophosphamide; Drainage; Fluoroura | 1980 |
Relief of jaundice by 5-fluorouracil and folinic acid in patients with recurrent gastric cancer.
Topics: Adult; Aged; Antidotes; Antineoplastic Agents; Bile; Drug Administration Schedule; Drug Synergism; D | 1996 |
Squamous cell carcinoma of the pancreas with cystic degeneration.
Topics: Abdominal Pain; Anorexia; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Squamou | 2000 |
Adenocarcinoma of the bile ducts. Relationship of anatomic location to clinical features.
Topics: Adenocarcinoma; Adult; Aged; Alkaline Phosphatase; Bile Duct Neoplasms; Bile Ducts; Bile Ducts, Intr | 1975 |
Jaundice and intrahepatic cholestasis following high-dose megestrol acetate for breast cancer.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; Breast Neoplasms; Cholestasis, Intr | 1989 |
Prolonged intermittent arterial infusion for metastatic carcinoma of the liver.
Topics: Adult; Aged; Catheterization; Chemotherapy, Cancer, Regional Perfusion; Female; Fluorouracil; Hepati | 1972 |
Intra-arterial chemotherapy for patients with inoperable carcinoma of the pancreas.
Topics: Catheterization; Cyclophosphamide; Fluorouracil; Humans; Injections, Intra-Arterial; Jaundice; Metho | 1974 |
Results of 27 cases with hepatic metastases treated by combination chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Fluorouracil; Humans; | 1972 |
The treatment of jaundice due to liver metastases by quadruple chemotherapy.
Topics: Aged; Antineoplastic Agents; Cyclophosphamide; Fluorouracil; Humans; Jaundice; Liver Neoplasms; Meth | 1973 |