Page last updated: 2024-10-27

fluorouracil and Jaundice, Obstructive

fluorouracil has been researched along with Jaundice, Obstructive in 6 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Jaundice, Obstructive: Jaundice, the condition with yellowish staining of the skin and mucous membranes, that is due to impaired BILE flow in the BILIARY TRACT, such as INTRAHEPATIC CHOLESTASIS, or EXTRAHEPATIC CHOLESTASIS.

Research Excerpts

ExcerptRelevanceReference
" Retention of ascites, peritoneal dissemination, obstructive jaundice and right hydronephrosis appeared in June, 2003, and we started combination chemotherapy with paclitaxel and 5-fluorouracil."3.73[A case report of recurrent gastric cancer in which combination chemotherapy with paclitaxel and 5-fluorouracil made for successful biliary stenting and improvement in QOL]. ( Miyade, Y; Ninomiya, M; Ohtani, S; Shimizu, Y; Sugiyama, S, 2005)
"It is important to understand that gastric cancer diagnosed poorly differentiated adenocarcinoma pathologically sometimes occurs duodenal invasion and obstructive jaundice."1.36[A case of duodenal invasion due to recurrent gastric cancer with obstructive jaundice treated by chemotherapy]. ( Fukuda, S; Hiraki, S; Kawaoka, T; Matsukuma, S; Nagashima, A, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishiguro, T1
Kitaoka, T1
Sakimoto, T1
Miyazaki, T1
Yokoyama, M1
Ishibashi, K1
Matsuki, M1
Inoue, N1
Sano, M1
Ishida, H1
Kawaoka, T1
Matsukuma, S1
Nagashima, A1
Hiraki, S1
Fukuda, S1
Matsui, T1
Kojima, H1
Kato, J1
Uemura, T1
Kojima, T1
Fujimitsu, Y1
Tanehiro, K1
Inagaki, H1
Sakamoto, J1
Gerke, H1
White, R1
Byrne, MF1
Stiffier, H1
Mitchell, RM1
Hurwitz, HI1
Morse, MA1
Branch, MS1
Jowell, PS1
Czito, B1
Clary, B1
Pappas, TN1
Tyler, DS1
Baillie, J1
Ohtani, S1
Shimizu, Y1
Sugiyama, S1
Miyade, Y1
Ninomiya, M1
Ebisui, C1
Fujiwara, S1
Hayashi, N1
Fukuchi, N1
Tsujie, M1
Yoshida, T1
Sakita, I1
Hasuike, Y1
Fujimoto, T1

Other Studies

6 other studies available for fluorouracil and Jaundice, Obstructive

ArticleYear
[Modified FOLFOX6 treatment for obstructive jaundice caused by hepatic lymph-node metastasis from liver metastases of rectal cancer--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2008, Volume: 35, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Female; Fluorouracil; Huma

2008
[A case of duodenal invasion due to recurrent gastric cancer with obstructive jaundice treated by chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:12

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phyto

2010
[A case report of unresectable gastric cancer that responded to 5-FU plus paclitaxel (FT) therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2004, Volume: 31, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Ascites; Drug Administration Schedule; Fluorouracil;

2004
Complications of pancreaticoduodenectomy after neoadjuvant chemoradiation in patients with and without preoperative biliary drainage.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Ampulla of Vater; Antimetabolites, Antineoplastic; Bile; Chemotherap

2004
[A case report of recurrent gastric cancer in which combination chemotherapy with paclitaxel and 5-fluorouracil made for successful biliary stenting and improvement in QOL].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Ascites; Biliary Tract; Chemotherapy, Adjuvant; Drug

2005
[A case of colon cancer liver metastases treated by combined therapies].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Catheter Ablation; Chemotherapy, Adjuvant; Colon, Si

2006