fluorouracil has been researched along with Itching in 10 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Keloids and hypertrophic scars are benign growths of dermal collagen that can cause physical and psychological (cosmetic) problems for patients." | 6.74 | Intralesional triamcinolone alone or in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. ( Asilian, A; Darougheh, A; Shariati, F, 2009) |
| "Keloids and hypertrophic scars are benign growths of dermal collagen that can cause physical and psychological (cosmetic) problems for patients." | 2.74 | Intralesional triamcinolone alone or in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars. ( Asilian, A; Darougheh, A; Shariati, F, 2009) |
| " The frequency of grade 3 and 4 adverse effects were comparatively assessed in each treatment arm." | 1.39 | Comparative assessment of skin and subcutaneous toxicity in patients of advanced colorectal carcinoma treated with different schedules of FOLFOX. ( Bano, N; Mateen, A; Najam, R, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Chiang, TY | 1 |
| Hsu, HC | 1 |
| Jane, SW | 1 |
| Chen, SC | 1 |
| Probst, EA | 1 |
| Smith, AL | 1 |
| Abad, JD | 1 |
| Dalenc, F | 1 |
| Ribet, V | 1 |
| Rossi, AB | 1 |
| Guyonnaud, J | 1 |
| Bernard-Marty, C | 1 |
| de Lafontan, B | 1 |
| Salas, S | 1 |
| Ranc Royo, AL | 1 |
| Sarda, C | 1 |
| Levasseur, N | 1 |
| Massabeau, C | 1 |
| Levecq, JM | 1 |
| Dulguerova, P | 1 |
| Guerrero, D | 1 |
| Sibaud, V | 1 |
| Bano, N | 1 |
| Najam, R | 1 |
| Mateen, A | 1 |
| Darougheh, A | 1 |
| Asilian, A | 1 |
| Shariati, F | 1 |
| Poligone, B | 1 |
| Christensen, SR | 1 |
| Lazova, R | 1 |
| Heald, PW | 1 |
| Karlin, DA | 1 |
| Stroehlein, JR | 1 |
| Scialla, SJ | 1 |
| Miskoff, RA | 1 |
| Ingis, DA | 1 |
| Farmer, RG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Role of 5-Fluorouracil in Post-Operative Scar Formation Following Direct Brow Ptosis Repair[NCT03219580] | Phase 3 | 50 participants (Anticipated) | Interventional | 2017-05-20 | Enrolling by invitation | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for fluorouracil and Itching
| Article | Year |
|---|---|
Efficacy of a global supportive skin care programme with hydrotherapy after non-metastatic breast cancer treatment: A randomised, controlled study.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; | 2018 |
Intralesional triamcinolone alone or in combination with 5-fluorouracil for the treatment of keloid and hypertrophic scars.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cicatrix, Hypertrophic; Double-Blind Method; Drug | 2009 |
8 other studies available for fluorouracil and Itching
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
EGFRI-associated health-related quality of life by severity of skin toxicity in metastatic colorectal cancer patients receiving epidermal growth factor receptor inhibitor target therapy.
Topics: Acneiform Eruptions; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; | 2020 |
What is causing this patient's severe pruritus?
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; CA-19-9 Antigen; | 2020 |
Comparative assessment of skin and subcutaneous toxicity in patients of advanced colorectal carcinoma treated with different schedules of FOLFOX.
Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Colorectal | 2013 |
Bazex syndrome (acrokeratosis paraneoplastica).
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Ear, External; | 2007 |
Rash, nephritis, hypertension, and haemolysis in patient on 5-fluorouracil, doxorubicin, and mitomycin-C.
Topics: Aged; Anemia, Hemolytic; Antineoplastic Agents; Doxorubicin; Drug Eruptions; Drug Therapy, Combinati | 1980 |
Basal-cell carcinoma. A case unmasked by systemic fluorouracil therapy.
Topics: Administration, Topical; Carcinoma, Basal Cell; Diarrhea; Fluorouracil; Humans; Injections, Intraven | 1976 |
Adenocarcinoma of the bile ducts. Relationship of anatomic location to clinical features.
Topics: Adenocarcinoma; Adult; Aged; Alkaline Phosphatase; Bile Duct Neoplasms; Bile Ducts; Bile Ducts, Intr | 1975 |