fluorouracil has been researched along with Iris Neoplasms in 4 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Iris Neoplasms: Tumors of the iris characterized by increased pigmentation of melanocytes. Iris nevi are composed of proliferated melanocytes and are associated with neurofibromatosis and malignant melanoma of the choroid and ciliary body. Malignant melanoma of the iris often originates from preexisting nevi.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ocular metastasis in patients with esophageal cancer is quite rare." | 1.33 | Iris metastasis of esophageal cancer. ( Hirose, N; Ichiki, Y; Morita, M; Sugio, K; Yano, K; Yasumoto, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ichiki, Y | 1 |
| Morita, M | 1 |
| Yano, K | 1 |
| Sugio, K | 1 |
| Yasumoto, K | 1 |
| Hirose, N | 1 |
| Lee, WB | 1 |
| Sy, HM | 1 |
| Filip, DJ | 1 |
| Grossniklaus, HE | 1 |
| Bak, A | 1 |
| Rootman, J | 1 |
| Kumi, C | 1 |
| Bussanich, N | 1 |
| Damji, K | 1 |
| Gudauskas, G | 1 |
4 other studies available for fluorouracil and Iris Neoplasms
| Article | Year |
|---|---|
Iris metastasis of esophageal cancer.
Topics: Carcinoma, Squamous Cell; Esophageal Neoplasms; Fluorouracil; Humans; Iris Neoplasms; Male; Middle A | 2005 |
Metastatic esophageal adenocarcinoma presenting in the iris.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Capecitabine; Deo | 2007 |
[A case of Cogan-Reese syndrome (iris nevus syndrome)].
Topics: Adult; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; F | 1997 |
Effect of subconjunctivally administered antineoplastics on experimentally induced intraocular malignant tumour.
Topics: Animals; Antineoplastic Agents; Conjunctiva; Cytarabine; Female; Fluorouracil; Injections; Iris Neop | 1989 |