fluorouracil has been researched along with Intraocular Pressure in 310 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To demonstrate that preoperative treatment for 28 days with topical dorzolamide/timolol is non-inferior (Δ = 4 mm Hg) to oral acetazolamide and topical dexamethasone (standard therapy) in terms of intraocular pressure (IOP) reduction 3 and 6 months after trabeculectomy in glaucoma patients." | 9.24 | Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma. ( Bell, K; Keicher, A; Lorenz, K; Pfeiffer, N; Renieri, G; Ruckes, C; Thieme, H; Wasielica-Poslednik, J, 2017) |
| "To compare the efficacy of transconjunctival needling revision with 5-fluorouracil versus medical treatment in glaucomatous eyes with uncontrolled intraocular pressure due to encapsulated bleb after trabeculectomy." | 9.17 | Early transconjunctival needling revision with 5-fluorouracil versus medical treatment in encapsulated blebs: a 12-month prospective study. ( Susanna, R; Suzuki, R, 2013) |
| "To compare the effectiveness of trabeculectomy with adjunctive, low-dose, subconjunctival 5-fluorouracil (5-FU) to trabeculectomy alone in patients with uncomplicated glaucoma undergoing their first incisional surgical procedure." | 9.09 | Low-dose 5-fluorouracil trabeculectomy as initial surgery in uncomplicated glaucoma: long-term followup. ( Liebmann, JM; Ritch, R; Rothman, RF, 2000) |
| "In a randomized clinical trial, the authors compared the use of postoperative subconjunctival injections of 5-fluorouracil (5-FU) in 19 eyes with a single intraoperative application of subconjunctival mitomycin (MMC) at the filtering site in 20 eyes at high risk for failure of glaucoma filtering surgery." | 9.07 | Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery. ( Beeson, CC; Bergstrom, TJ; Falck, FY; Higginbotham, EJ; Klein, TB; Lichter, PR; Musch, DC; Skuta, GL, 1992) |
| " We concluded mitomycin C might be more effective in reducing intraocular pressure and increasing qualified success compared to 5-fluorouracil." | 8.98 | Is mytomicyn better than 5-fluorouracil as antimetabolite in trabeculectomy for glaucoma? ( Pimentel, E; Schmidt, J, 2018) |
| "To report the effectiveness and safety of 5-fluorouracil (5-FU)-augmented Xen45 implantation in primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEXG)." | 8.02 | Results of fluorouracil-augmented Xen45 implantation in primary open-angle and pseudoexfoliation glaucoma. ( Başer, EF; Seymenoğlu, RG, 2021) |
| "To investigate the outcomes of trabeculectomy with 5-fluorouracil (5-FU) with or without subconjunctival bevacizumab in the surgical management of pseudoexfoliation glaucoma (PXG)." | 7.91 | Initial trabeculectomy with 5-fluorouracil with or without subconjunctival bevacizumab in the management of pseudoexfoliation glaucoma. ( Çolak, S; Elgin, U; Sen, E; Yılmazbas, P, 2019) |
| "To report our experience on treatment of primary congenital glaucoma with trabeculectomy in combination with biological amniotic membranes soaked with 5-fluorouracil." | 7.88 | Retrospective observation on trabeculectomy of primary congenital glaucoma by applying biological amniotic membranes soaked with 5-fluorouracil. ( Gao, H; Guo, B; Liu, C; Liu, W; Wang, J; Wang, X; Wu, M; Zhang, C, 2018) |
| "To examine the effect of mitomycin c and 5-flurouracil on treatment outcomes following Ahmed glaucoma valve implantation." | 7.85 | Effect of mitomycin c and 5-flurouracil adjuvant therapy on the outcomes of Ahmed glaucoma valve implantation. ( Cui, QN; Han, Y; Hsia, YC; Lin, SC; Mehta, N; Naseri, A; Porco, TC; Rose-Nussbaumer, J; Stamper, RL, 2017) |
| "This study was designed to investigate whether 5-fluorouracil (5-Fu)-polycaprolactone sustained-release film in Ahmed glaucoma valve implantation inhibits postoperative bleb scarring in rabbit eyes." | 7.81 | Application of 5-Fluorouracil-Polycaprolactone Sustained-Release Film in Ahmed Glaucoma Valve Implantation Inhibits Postoperative Bleb Scarring in Rabbit Eyes. ( Bi, XZ; Li, CH; Nan, KH; Pan, WH; Ren, ZJ; Song, ZM; Sun, M; Yu, XP, 2015) |
| "To evaluate the antimitotic and toxic effects of 5-chlorouracil (5-CU) and 5-fluorouracil (5-FU) and study their potential to delay filtering bleb closure in the rabbit eye when released by poly(ortho esters) (POE)." | 7.74 | Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma. ( Behar-Cohen, F; BenEzra, D; Bourges, JL; Felt, O; Gurny, R; Jeanny, JC; Polak, MB; Rat, P; Thomas-Doyle, A; Torriglia, A; Valamanesh, F, 2008) |
| "Although adjunctive postoperative 5-fluorouracil (5-FU) injections are known to improve the success rate of glaucoma surgery, it is still unknown what dose, timing and frequency of application will give the best results with respect to the inhibition of postoperative scarring and intraocular pressure regulation." | 7.74 | Dose, timing and frequency of subconjunctival 5-fluorouracil injections after glaucoma filtering surgery. ( Bartz-Schmidt, KU; Besch, D; Denk, PO; Grüb, M; Reinthal, EK, 2007) |
| "To prospectively study the evolution of possible high risk features of conjunctival filtration blebs like avascularity, transconjunctival oozing (TCO), and leaks after mitomycin C (MMC) enhanced glaucoma surgery." | 7.73 | Mitomycin C augmented glaucoma surgery: evolution of filtering bleb avascularity, transconjunctival oozing, and leaks. ( Anand, N; Arora, S; Clowes, M, 2006) |
| "To report the outcome of 5-fluorouracil (5-FU)-augmented bleb needling revision of failed and failing filtration blebs and to identify risk factors for failure, indicators for success, and any complications of the procedure." | 7.72 | Needle revision of failing and failed trabeculectomy blebs with adjunctive 5-fluorouracil: survival analysis. ( Bloom, PA; Broadway, DC; Bunce, C; Khaw, PT; Thiagarajan, M, 2004) |
| "To investigate the changes of tear film functions due to the use of postoperative 5-fluourouracil (5-Fu) and intraoperative mitomycin C (MMC) in glaucoma filtration surgery." | 7.71 | [Influence on tear film of postoperative 5-fluourouracil and intraoperative mitomycin C in glaucoma filtration surgery]. ( Li, J; Pang, L, 2001) |
| "The authors evaluate the results of preoperative 5-minute administration of 5-fluorouracil (5-FU), 50 mg/ml, during trabeculectomy on 11 high risk eyes of children with primary and secondary glaucoma." | 7.70 | [Peroperative administration of 5-fluorouracil during trabeculectomy in complicated glaucoma in children]. ( Burdová, M; Filous, A, 1998) |
| "To determine the effect of intraoperative application of 5-fluorouracil (5-FU) on the long-term outcome of trabeculectomy in uveitis-related glaucoma." | 7.70 | Long-term follow-up of trabeculectomy with intraoperative 5-fluorouracil for uveitis-related glaucoma. ( Lightman, S; McCluskey, P; Shaer, B; Towler, HM, 2000) |
| "Patients with both cataract and glaucoma underwent combined mitomycin C trabeculectomy, extracapsular cataract extraction, and intraocular lens implantation." | 7.69 | One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction. ( Bueche, MJ; Feuer, WJ; Grajewski, AL; Joos, KM; Palmberg, PF, 1995) |
| "Between 2/1991 and 1/1993 twenty-nine eyes of 11 female and 16 male patients with high-risk glaucoma (unsuccessful previous filtering surgery and a high risk of scarring) were treated with subconjunctival injections of 5-Fluorouracil after filtering surgery in the University Eye Hospital Düsseldorf." | 7.68 | [5-fluorouracil injection treatment after fistulating glaucoma operations]. ( Klüppel, M; Reinhard, T; Sundmacher, R, 1993) |
| "We studied 105 patients (105 eyes) operated on for glaucoma with adjunctive fluorouracil, who were followed up for 12 to 48 months (mean, 34." | 7.68 | Late complications after glaucoma filtering surgery with adjunctive 5-fluorouracil. ( Ophir, A; Ticho, U, 1993) |
| "Twenty-one eyes of 18 patients with uncontrolled glaucoma and intraocular inflammatory disease had glaucoma filtering surgery with postoperative subconjunctival 5-fluorouracil (5-FU)." | 7.68 | Glaucoma filtering surgery with postoperative 5-fluorouracil in patients with intraocular inflammatory disease. ( Lowder, CY; Meisler, DM; Patitsas, CJ; Rockwood, EJ, 1992) |
| "Trabeculectomy and subsequent subconjunctival injections of 5-fluorouracil (5-FU) were performed in four eyes (two children) with congenital glaucoma." | 7.68 | Subconjunctival injection of 5-fluorouracil following trabeculectomy for congenital and infantile glaucoma. ( Leiba, H; Oliver, M; Zalish, M, 1992) |
| "The effectiveness of trabeculectomy with adjunctive low-dose 5-fluorouracil (5-FU) as the initial surgical procedure in uncomplicated glaucoma was evaluated retrospectively in a consecutive series of 52 patients (mean follow-up, 18." | 7.68 | Initial 5-fluorouracil trabeculectomy in uncomplicated glaucoma. ( Liebmann, JM; Marmor, M; Nunez, J; Ritch, R; Wolner, B, 1991) |
| "The incidence of late-onset bleb-related endophthalmitis was evaluated retrospectively in 229 consecutive trabeculectomies performed with adjunctive 5-fluorouracil (5-FU) therapy." | 7.68 | Late bleb-related endophthalmitis after trabeculectomy with adjunctive 5-fluorouracil. ( Liebmann, JM; Marmor, M; Ritch, R; Sassani, JW; Speaker, M; Wolner, B, 1991) |
| "Nine patients (nine eyes) with iridocorneal endothelial (ICE) syndrome underwent trabeculectomy and received postoperative subconjunctival injections of 5-fluorouracil (5-FU) to enhance bleb formation (total 5-FU dose, 30-105 mg; mean, 53." | 7.68 | 5-Fluorouracil after trabeculectomy and the iridocorneal endothelial syndrome. ( Cristol, SM; Grajewski, AL; Parrish, RK; Wright, MM, 1991) |
| "We reviewed the records of 12 eyes of ten adult patients with inflammatory glaucoma who underwent trabeculectomy with the adjuvant use of 5-fluorouracil between January 1986 and January 1989." | 7.68 | Trabeculectomy with 5-fluorouracil for adult inflammatory glaucoma. ( Jabs, DA; Jampel, HD; Quigley, HA, 1990) |
| "5-Fluorouracil (5-FU) was injected subconjunctivally after glaucoma filtering surgery in a pilot study of eyes with poor surgical prognoses." | 7.67 | 5-fluorouracil and glaucoma filtering surgery. II. A pilot study. ( Anderson, DR; Gressel, MG; Heuer, DK; Hodapp, E; Palmberg, PF; Parrish, RK, 1984) |
| "We show that a 40-mg total dose of subconjunctival 5-fluorouracil after glaucoma filtering surgery can provide a success rate comparable to that demonstrated in prior studies employing a higher dose." | 7.67 | Low-dose 5-fluorouracil and glaucoma filtration surgery. ( Rabowsky, JH; Ruderman, JM, 1989) |
| "A prospective, randomized, double-masked, and placebo-controlled study was performed to examine the effect of a localized and sustained delivery of 5-fluorouracil (5-FU) on the success of glaucoma filtration surgery in 18 rabbits." | 7.67 | Glaucoma filtration surgery in rabbits using bioerodible polymers and 5-fluorouracil. ( Anderson, PJ; de Kater, AW; Flores, RA; Hertzmark, E; Lee, DA; Leong, KW; Teekhasaenee, C, 1987) |
| "The effect of 5-fluorouracil (5-FU) subconjunctival injection on the bleb formation and intraocular pressure (IOP) following trabeculectomy was studied in 18 glaucoma patients (20 eyes) with poor surgical prognosis." | 7.67 | 5-Fluorouracil for trabeculectomy in glaucoma. ( Kitazawa, Y; Nakano, Y; Shirato, S; Taniguchi, T; Yamamoto, T, 1987) |
| "Last controlled intraocular pressure is lower in C group patients (13." | 6.68 | [Intra- and postoperative use of 5-fluorouracil in the surgical treatment of refractory glaucoma]. ( Apatachioaie, I; Brănişteanu, D; Chiseliţă, D; Poiata, I; Rusu, V; Tătăruş, C, 1997) |
| "Late postoperative complications are similar with the exception of an increased incidence of Tenon cyst formation in the MMC-treated eyes." | 6.68 | Mitomycin C versus 5-fluorouracil in high-risk glaucoma filtering surgery. Extended follow-up. ( Bergstrom, TJ; Higginbotham, EJ; Johnson, AT; Katz, GJ; Lichter, PR; Musch, DC; Skuta, GL, 1995) |
| "Intraocular pressure was 20 mm Hg or lower in 24 eyes (96%) in the treatment group after mean follow-up of 17." | 6.67 | A randomized study of trabeculectomy and subconjunctival administration of fluorouracil in primary glaucomas. ( Ophir, A; Ticho, U, 1992) |
| "Raised intraocular pressure is a risk factor for glaucoma." | 6.52 | Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery. ( Cabourne, E; Clarke, JC; Evans, JR; Schlottmann, PG, 2015) |
| "Mitomycin C seems to be a better treatment than 5 fluorouracil." | 6.38 | [Mitomycin C in glaucoma surgery]. ( Collignon-Brach, J, 1993) |
| "5-Fluorouracil (5-FU) has been well described for a failing trabeculectomy bleb, but not for aqueous shunts." | 5.46 | Use of subconjunctival injections of 5-fluorouracil to rescue and prolong intraocular pressure reduction for a failing Ahmed glaucoma implant. ( Kaplowitz, K; Khodadadeh, S; Lee, D; Tsai, JC; Wang, S, 2017) |
| " In this study, 5-Fluorouracil (5-FU), a halogenated pyrimidine analogue and a potent anti-mitotic agent, was applied for seven days after trabeculectomy in eighteen complicated and unsuccessful filtering glaucomas, at a daily dosage of 5 mg in the form of 0." | 5.29 | The role of 5-fluorouracil in complicated glaucomas. ( Das, S; Jilani, FA; Khan, AM, 1993) |
| "The objective of this article was to study longitudinal changes in bleb morphology (presence of microcysts and bleb height and vascularity) in subjects enrolled in the Singapore 5-Fluorouracil (5-FU) trabeculectomy study." | 5.27 | Longitudinal Changes in Bleb Height, Vascularity, and Conjunctival Microcysts After Trabeculectomy. ( Aung, T; Htoon, HM; Husain, R; Kumaran, A, 2018) |
| "5-fluorouracil is an antimetabolite capable of inhibiting fibroblast proliferation." | 5.27 | 5-fluorouracil and glaucoma filtering surgery: I. An animal model. ( Folberg, R; Gressel, MG; Parrish, RK, 1984) |
| "To demonstrate that preoperative treatment for 28 days with topical dorzolamide/timolol is non-inferior (Δ = 4 mm Hg) to oral acetazolamide and topical dexamethasone (standard therapy) in terms of intraocular pressure (IOP) reduction 3 and 6 months after trabeculectomy in glaucoma patients." | 5.24 | Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma. ( Bell, K; Keicher, A; Lorenz, K; Pfeiffer, N; Renieri, G; Ruckes, C; Thieme, H; Wasielica-Poslednik, J, 2017) |
| "To compare the efficacy of transconjunctival needling revision with 5-fluorouracil versus medical treatment in glaucomatous eyes with uncontrolled intraocular pressure due to encapsulated bleb after trabeculectomy." | 5.17 | Early transconjunctival needling revision with 5-fluorouracil versus medical treatment in encapsulated blebs: a 12-month prospective study. ( Susanna, R; Suzuki, R, 2013) |
| "Primary outcome was bleb vascularity with secondary endpoints including visual acuity, intraocular pressure, bleb morphology, complications and total numbers of 5-fluorouracil injections were recorded at baseline, week 12 and 18 months." | 5.16 | Bleb vascularity following post-trabeculectomy subconjunctival bevacizumab: a pilot study. ( Chua, BE; Coote, MA; Crowston, JG; Gupta, V; Nguyen, DQ; Niyadurupola, N; Qin, Q; Ruddle, JB; Wells, AP; Wong, TT, 2012) |
| "Patients aged ≥ 30 years newly diagnosed with glaucoma were randomized to trabeculectomy with 5-fluorouracil or medical therapy." | 5.16 | A study of initial therapy for glaucoma in southern India: India Glaucoma Outcomes and Treatment (INGOT) Study. ( Congdon, NG; Friedman, DS; Gilbert, D; Goggins, W; Kader, MA; Krishnadas, R; Quigley, HA; Ramakrishnan, R; Tielsch, J, 2012) |
| "The perioperative use of oral prednisone did not alter the surgical outcome of filtering procedures associated with antifibrosis agents in this population of glaucoma patients." | 5.09 | Oral prednisone in guarded filtration procedures supplemented with antimetabolites. ( Augsburger, JJ; Azuara-Blanco, A; Spaeth, GL, 1999) |
| "To compare the effectiveness of trabeculectomy with adjunctive, low-dose, subconjunctival 5-fluorouracil (5-FU) to trabeculectomy alone in patients with uncomplicated glaucoma undergoing their first incisional surgical procedure." | 5.09 | Low-dose 5-fluorouracil trabeculectomy as initial surgery in uncomplicated glaucoma: long-term followup. ( Liebmann, JM; Ritch, R; Rothman, RF, 2000) |
| "Mean (+/-SD) preoperative and 1-year postoperative intraocular pressures in the 5-fluorouracil group were 26." | 5.09 | Randomized, controlled study of low-dose 5-fluorouracil in primary trabeculectomy. ( Caprioli, J; Chaudhry, IA; O'Connor, DJ; Pasha, MA; Weitzman, ML, 2000) |
| "Trabeculectomy is the procedure of choice for the surgical control of glaucoma, and is often augmented by intraoperative 5-fluorouracil application to reduce scarring." | 5.09 | Single intraoperative application of 5-Fluorouracil versus placebo in low-risk trabeculectomy surgery: a randomized trial. ( Bloom, P; Leyland, M; McAlister, J; Migdal, C; Rassam, S; Zinicola, E, 2001) |
| "To determine the efficacy and safety of subconjunctival 5- fluorouracil injections after trabeculectomy in patients with poor prognoses, to determine risk factors for surgical failure and to examine the relationship of intraocular pressure and visual function." | 5.08 | Five-year follow-up of the Fluorouracil Filtering Surgery Study. The Fluorouracil Filtering Surgery Study Group. ( , 1996) |
| "To study the effect of 5-Fluorouracil (5-FU) in glaucoma filtration surgery, 13 eyes of 12 patients with glaucoma were subjected to trabeculectomy with intraoperative one minute exposure of 50 mg/ml 5-FU." | 5.08 | Results of intraoperative 5-fluorouracil in patients undergoing trabeculectomy--pilot trial. ( Garg, D; Rao, BS; Revathi, B; Shelat, B; Vijaya, L, 1996) |
| "We examined the safety and efficacy of 5-fluorouracil in eyes with open-angle glaucoma undergoing combined cataract removal and filtration surgery." | 5.07 | 5-Fluorouracil after primary combined filtration surgery. ( Gieser, DK; Goldenfeld, M; Krupin, T; Liebmann, JM; Ritch, R; Rosenberg, LF; Ruderman, JM; Shields, MB; Wong, PC, 1994) |
| "The effects of postoperative subconjunctival 5-fluorouracil (5-FU) injections on the surgical outcomes of trabeculectomy were studied after a 5-year follow-up in 263 eyes of glaucoma patients by the life table analysis." | 5.07 | [A five-year follow-up of the effect of postoperative 5-fluorouracil subconjunctival injections on the surgical outcome of trabeculectomy]. ( Araie, M; Nakano, Y; Shirato, S; Shoji, N, 1993) |
| "Eighteen eyes of 15 patients with uncontrolled glaucoma (neovascular, intracapsular aphakia, uveitic, previous filtration failure) at high risk for failure of standard filtration underwent trabeculectomy with implantation of a purified collagen sponge containing 100 micrograms of antimetabolite (5-fluorouracil or bleomycin)." | 5.07 | Long-term results of trabeculectomy with collagen sponge implant containing low-dose antimetabolite. ( Herschler, J, 1992) |
| "In a randomized clinical trial, the authors compared the use of postoperative subconjunctival injections of 5-fluorouracil (5-FU) in 19 eyes with a single intraoperative application of subconjunctival mitomycin (MMC) at the filtering site in 20 eyes at high risk for failure of glaucoma filtering surgery." | 5.07 | Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery. ( Beeson, CC; Bergstrom, TJ; Falck, FY; Higginbotham, EJ; Klein, TB; Lichter, PR; Musch, DC; Skuta, GL, 1992) |
| "We conducted a prospective, randomized study to compare mitomycin with fluorouracil for efficacy and safety as an adjunct to trabeculectomy in eyes with glaucoma with poor surgical prognosis." | 5.07 | Trabeculectomy with mitomycin. A comparative study with fluorouracil. ( Kawase, K; Kitazawa, Y; Matsushita, H; Minobe, M, 1991) |
| " We concluded mitomycin C might be more effective in reducing intraocular pressure and increasing qualified success compared to 5-fluorouracil." | 4.98 | Is mytomicyn better than 5-fluorouracil as antimetabolite in trabeculectomy for glaucoma? ( Pimentel, E; Schmidt, J, 2018) |
| "The preponderance of evidence from the literature suggests a small (2-4 mmHg) benefit from the use of mitomycin-C (MMC), but not 5-fluorouracil (5-FU), in combined cataract and glaucoma surgery (evidence grade B)." | 4.81 | Effect of technique on intraocular pressure after combined cataract and glaucoma surgery: An evidence-based review. ( Bass, EB; Congdon, N; Friedman, DS; Jampel, HD; Kempen, JH; Levkovitch-Verbin, H; Lubomski, LH; Quigley, H; Robinson, KA, 2002) |
| "To examine why most ophthalmologists routinely use mitomycin C or 5-fluorouracil (antimetabolites) in association with filtering surgery for glaucoma." | 4.81 | The use of antimetabolites with trabeculectomy: a critical appraisal. ( Mutlukan, E; Spaeth, GL, 2001) |
| "To report the effectiveness and safety of 5-fluorouracil (5-FU)-augmented Xen45 implantation in primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PEXG)." | 4.02 | Results of fluorouracil-augmented Xen45 implantation in primary open-angle and pseudoexfoliation glaucoma. ( Başer, EF; Seymenoğlu, RG, 2021) |
| "To investigate the outcomes of trabeculectomy with 5-fluorouracil (5-FU) with or without subconjunctival bevacizumab in the surgical management of pseudoexfoliation glaucoma (PXG)." | 3.91 | Initial trabeculectomy with 5-fluorouracil with or without subconjunctival bevacizumab in the management of pseudoexfoliation glaucoma. ( Çolak, S; Elgin, U; Sen, E; Yılmazbas, P, 2019) |
| "Rabbit model studies suggested better morphology blebs with equal intraocular pressure (IOP) efficacy as a standard mitomycin C (MMC) trabeculectomy using a novel slow-release drug delivery antifibrotic system delivering small quantities of MMC and 5-fluorouracil (5-FU)." | 3.91 | Effect of 2 Novel Sustained-release Drug Release Systems on Bleb Fibrosis: An In Vivo Trabeculectomy Study in a Rabbit Model. ( Ayyala, RS; Blake, D; Fullerton, M; Greenberg, E; John, V; Le, C; Mancera, N; Margo, C; Muddasani, N; Satija, C; Singh, S; Swann, FB; Wall, J; Zhang, Z; Zurakowski, D, 2019) |
| "To report our experience on treatment of primary congenital glaucoma with trabeculectomy in combination with biological amniotic membranes soaked with 5-fluorouracil." | 3.88 | Retrospective observation on trabeculectomy of primary congenital glaucoma by applying biological amniotic membranes soaked with 5-fluorouracil. ( Gao, H; Guo, B; Liu, C; Liu, W; Wang, J; Wang, X; Wu, M; Zhang, C, 2018) |
| "To evaluate the long-term outcome of trabeculectomy with intra- and postoperative 5-fluorouracil (5-FU) application in glaucoma." | 3.85 | Three-Year Follow-Up of Trabeculectomy with 5-Fluorouracil. ( Koutsonas, A; Kuerten, D; Lindemann, F; Plange, N; Schimitzek, H, 2017) |
| "To examine the effect of mitomycin c and 5-flurouracil on treatment outcomes following Ahmed glaucoma valve implantation." | 3.85 | Effect of mitomycin c and 5-flurouracil adjuvant therapy on the outcomes of Ahmed glaucoma valve implantation. ( Cui, QN; Han, Y; Hsia, YC; Lin, SC; Mehta, N; Naseri, A; Porco, TC; Rose-Nussbaumer, J; Stamper, RL, 2017) |
| "To determine the outcome of needling with adjunctive 5-fluorouracil (5-FU) in patients with a failing Ahmed glaucoma valve (AGV) implant, and to identify predictors of long-term intraocular pressure (IOP) control." | 3.83 | Needle Revision With 5-fluorouracil for the Treatment of Ahmed Glaucoma Valve Filtering Blebs: 5-Fluoruracil Needling Revision can be a Useful and Safe Tool in the Management of Failing Ahmed Glaucoma Valve Filtering Blebs. ( Floriani, I; Hollander, L; Katsanos, A; Konstas, AG; Poli, D; Quaranta, L, 2016) |
| "To compare the complication rate and effectiveness of mitomycin C (MMC), Ologen alone, and Ologen with 5-fluorouracil (5-FU) as adjunctives with Ex-PRESS mini shunt for medically uncontrolled glaucoma." | 3.81 | Ex-PRESS outcomes using mitomycin-C, Ologen alone, Ologen with 5-fluorouracil. ( Han, Y; Lowry, EA; Menda, SA; Porco, TC; Rubin, MR; Stamper, RL, 2015) |
| "This study was designed to investigate whether 5-fluorouracil (5-Fu)-polycaprolactone sustained-release film in Ahmed glaucoma valve implantation inhibits postoperative bleb scarring in rabbit eyes." | 3.81 | Application of 5-Fluorouracil-Polycaprolactone Sustained-Release Film in Ahmed Glaucoma Valve Implantation Inhibits Postoperative Bleb Scarring in Rabbit Eyes. ( Bi, XZ; Li, CH; Nan, KH; Pan, WH; Ren, ZJ; Song, ZM; Sun, M; Yu, XP, 2015) |
| "To investigate the safety and efficacy of Nd:YAG laser goniopuncture (LGP) in lowering intraocular pressure (IOP) in eyes having late bleb failure following trabeculectomy with mitomycin C administration." | 3.80 | Nd:YAG laser goniopuncture for late bleb failure after trabeculectomy with adjunctive mitomycin C. ( Alencar, LM; De Moraes, CG; Ritch, R; Susanna, R, 2014) |
| "To determine whether primary trabeculectomies performed in a UK district general hospital, specifically without making use of mitomycin-C augmentation but with selective use of the low potency anti-metabolite 5-fluorouracil, produce an acceptable long-term intraocular pressure (IOP)-lowering effect for an unselected patient group." | 3.79 | Enhanced trabeculectomy in a UK district general hospital setting: is selective use of 5-fluorouracil all that is required? ( Chaudhry, N; de Klerk, TA; Moriarty, AP, 2013) |
| "to investigate the ability of drug-loaded N,O-carboxymethyl chitosan (CMCS) hydrogels to modulate wound healing after glaucoma filtration surgery." | 3.76 | Ophthalmic drug-loaded N,O-carboxymethyl chitosan hydrogels: synthesis, in vitro and in vivo evaluation. ( CAI, X; CHEN, RF; CHENG, LZ; FAN, JZ; GUO, H; LAN, YQ; YANG, LQ; ZHANG, LM; ZHOU, HS, 2010) |
| " Intraocular pressure, visual acuity, complications and numbers of injections of 5-fluorouracil, suture removal, needling procedures and visits to ophthalmologists were recorded for 2 years." | 3.75 | Trabeculectomy with an active postoperative regimen: results and resource utilization. ( Alm, A; Niemelä, P; Taube, AB, 2009) |
| "To evaluate long-term outcomes after Ahmed valve implantation in patients with glaucoma when using adjunctive intraoperative mitomycin C (MMC) and postoperative 5-fluorouracil (5-FU)." | 3.74 | Ahmed valve implantation with adjunctive mitomycin C and 5-fluorouracil: long-term outcomes. ( Alvarado, JA; Hollander, DA; Juster, RP; Lee, LC, 2008) |
| "To evaluate the antimitotic and toxic effects of 5-chlorouracil (5-CU) and 5-fluorouracil (5-FU) and study their potential to delay filtering bleb closure in the rabbit eye when released by poly(ortho esters) (POE)." | 3.74 | Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma. ( Behar-Cohen, F; BenEzra, D; Bourges, JL; Felt, O; Gurny, R; Jeanny, JC; Polak, MB; Rat, P; Thomas-Doyle, A; Torriglia, A; Valamanesh, F, 2008) |
| "Although adjunctive postoperative 5-fluorouracil (5-FU) injections are known to improve the success rate of glaucoma surgery, it is still unknown what dose, timing and frequency of application will give the best results with respect to the inhibition of postoperative scarring and intraocular pressure regulation." | 3.74 | Dose, timing and frequency of subconjunctival 5-fluorouracil injections after glaucoma filtering surgery. ( Bartz-Schmidt, KU; Besch, D; Denk, PO; Grüb, M; Reinthal, EK, 2007) |
| "To report the experience with trabeculectomy augmented with mitomycin C and 5-fluorouracil for the treatment of paediatric glaucoma." | 3.73 | Augmented trabeculectomy in paediatric glaucoma. ( Ehrlich, R; Friling, R; Gaton, DD; Lusky, M; Snir, M; Weinberger, D, 2005) |
| "In this study we compared the two groups of glaucoma patients who had underwent trabeculectomy, with or without intraoperative application of antimetabolite 5-Fluorouracile (5 FU)." | 3.73 | [Visual acuty after trabeculectomy]. ( Buzarovska, KB; Dzajkovska, E; Jordanova, VD; Vukosavljević, M, 2005) |
| "To prospectively study the evolution of possible high risk features of conjunctival filtration blebs like avascularity, transconjunctival oozing (TCO), and leaks after mitomycin C (MMC) enhanced glaucoma surgery." | 3.73 | Mitomycin C augmented glaucoma surgery: evolution of filtering bleb avascularity, transconjunctival oozing, and leaks. ( Anand, N; Arora, S; Clowes, M, 2006) |
| "To investigate the effect on intraocular pressure (IOP) of intraoperative 5-fluorouracil (5-FU) application during primary trabeculectomy in a West African population." | 3.72 | Intraoperative 5-fluorouracil application during primary trabeculectomy in Nigeria: a comparative study. ( Anand, N; Dawda, VK; Mielke, C, 2003) |
| "To report the outcome of 5-fluorouracil (5-FU)-augmented bleb needling revision of failed and failing filtration blebs and to identify risk factors for failure, indicators for success, and any complications of the procedure." | 3.72 | Needle revision of failing and failed trabeculectomy blebs with adjunctive 5-fluorouracil: survival analysis. ( Bloom, PA; Broadway, DC; Bunce, C; Khaw, PT; Thiagarajan, M, 2004) |
| "To evaluate the effect of temporal corneal phacoemulsification on intraocular pressure (IOP) in eyes after primary trabeculectomy with intraoperative fluorouracil (5-FU) or mitomycin C (MMC)." | 3.72 | Effect of temporal corneal phacoemulsification on intraocular pressure in eyes with prior trabeculectomy with an antimetabolite. ( Cantor, LB; Capistrano, AP; Swamynathan, K; WuDunn, D, 2004) |
| "A retrospective chart review of 44 eyes of 44 patients with uveitic glaucoma who underwent trabeculectomy with mitomycin C or 5-fluorouracil." | 3.71 | Trabeculectomy with antiproliferative agents in uveitic glaucoma. ( Beck, AD; Ceballos, EM; Lynn, MJ, 2002) |
| "To investigate the changes of tear film functions due to the use of postoperative 5-fluourouracil (5-Fu) and intraoperative mitomycin C (MMC) in glaucoma filtration surgery." | 3.71 | [Influence on tear film of postoperative 5-fluourouracil and intraoperative mitomycin C in glaucoma filtration surgery]. ( Li, J; Pang, L, 2001) |
| "To assess the outcome of trabeculectomy supplemented with intraoperative 5-Fluorouracil (5 FU) application in glaucoma patients." | 3.70 | Modification of trabeculectomy with single-dose intraoperative 5-Fluorouracil application. ( Anand, N; Menage, MJ; Sahni, K, 1998) |
| "The authors evaluate the results of preoperative 5-minute administration of 5-fluorouracil (5-FU), 50 mg/ml, during trabeculectomy on 11 high risk eyes of children with primary and secondary glaucoma." | 3.70 | [Peroperative administration of 5-fluorouracil during trabeculectomy in complicated glaucoma in children]. ( Burdová, M; Filous, A, 1998) |
| "This retrospective study was undertaken to evaluate if a "low dose" intraoperative sponge 5-fluorouracil application may improve the quality of the postoperative IOP control without increasing the incidence of postoperative complications following a first trabeculectomy in low-risk and/or severe field defects glaucomatous patients comparatively with a control group." | 3.70 | [Use of "low dose" 5-fluorouracil during trabeculectomy]. ( Detry-Morel, M; Kolanowski, C, 1999) |
| "To determine and compare the intraocular pressure (IOP) lowering effects of single-incision combined phacoemulsification and trabeculectomy with phacoemulsification done after previous trabeculectomy, both with an intraoperative dose of 5-fluorouracil (5-FU)." | 3.70 | Combined versus sequential phacotrabeculectomy with intraoperative 5-fluorouracil. ( Donoso, R; Rodríguez, A, 2000) |
| "To determine the effect of intraoperative application of 5-fluorouracil (5-FU) on the long-term outcome of trabeculectomy in uveitis-related glaucoma." | 3.70 | Long-term follow-up of trabeculectomy with intraoperative 5-fluorouracil for uveitis-related glaucoma. ( Lightman, S; McCluskey, P; Shaer, B; Towler, HM, 2000) |
| "To study the association between after-cataract and secondary glaucoma after lensectomy and 5-fluorouracil treatment in an experimental infant rabbit model." | 3.70 | After-cataract and secondary glaucoma in the aphakic infant rabbit. ( Holmén, JB; Kugelberg, U; Lundgren, B; Lundvall, A; Zetterström, C, 2000) |
| "A concurrent series (from January 1, 1987, to October 1, 1997) of one surgeon's consecutive 585 (456 patients) combined cataract extraction, intraocular lens implantation, and trabeculectomy surgeries, some with intraoperative mitomycin C and/or postoperative subconjunctival 5-fluorouracil." | 3.70 | Outcomes of combined cataract extraction, lens implantation, and trabeculectomy surgeries. ( Hahn, J; Larive, B; Rockwood, EJ, 2000) |
| "The cytostatic 5-fluorouracil (5-FU) is used at present in the postoperative treatment of glaucoma." | 3.70 | [Use of 5-fluorouracil in trabeculectomy]. ( Hovorková, M; Kvasnicka, J; Lochman, J; Novák, J; Rozsíval, P, 2000) |
| " In the 56 eyes where 5-fluorouracil was not used, the mean intraocular pressure (IOP) on diagnosis was 33." | 3.69 | Intraocular pressure control following microtrabeculectomy. ( Spencer, AF; Vernon, SA, 1995) |
| "Patients with both cataract and glaucoma underwent combined mitomycin C trabeculectomy, extracapsular cataract extraction, and intraocular lens implantation." | 3.69 | One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction. ( Bueche, MJ; Feuer, WJ; Grajewski, AL; Joos, KM; Palmberg, PF, 1995) |
| "To evaluate intraocular pressure (IOP) control and surgical complications following trabeculectomy with 5-fluorouracil (5-FU) or mitomycin at the inferior limbus." | 3.69 | Trabeculectomy at the inferior limbus. ( Caronia, RM; Cohen, H; Friedman, R; Liebmann, JM; Ritch, R, 1996) |
| "A 2-month-old female infant with intractable congenital glaucoma and diffuse corneal opacification underwent trabeculectomy with 5-fluorouracil (5-FU) injection in both eyes followed by penetrating keratoplasty (PKP) combined with partial cyclocryotherapy in the right eye." | 3.69 | Ultrasonographic findings of the optic disc in congenital glaucoma. ( Barash, D; Kremer, I; Lusky, M; Snir, M; Yassur, Y, 1996) |
| "Forty consecutive case patients who underwent temporal corneal phacoemulsification combined with superior trabeculectomy plus low-dose 5-fluorouracil (case [combined surgery] group) and 40 control patients, matched for age race, preoperative intraocular pressure (IOP), number of preoperative antiglaucoma medications, and number of 5-fluorouracil injections, who underwent trabeculectomy alone plus low-dose 5-fluorouracil (control [trabeculectomy] group)." | 3.69 | Temporal corneal phacoemulsification combined with superior trabeculectomy. A retrospective case-control study. ( Caprioli, J; Park, HJ; Weitzman, M, 1997) |
| "The revision of a failed filtering bleb using mitomycin C was performed in 40 eyes (28 eyes with primary open angle glaucoma and 12 eyes with secondary open angle glaucoma) in which the previous trabeculectomy using 5-fluorouracil had failed to control intraocular pressure (IOP)." | 3.69 | [Surgical revision of failed filtering bleb with mitomycin C]. ( Hara, T; Shirato, S, 1997) |
| " Forty patients (controls; TRAB group) who had trabeculectomy alone were matched to the cases for length of follow-up, age, IOP, number of anti-glaucoma medications, number of 5-fluorouracil (5-FU) injections, race, sex and diagnosis." | 3.69 | Temporal corneal phacoemulsification in filtered glaucoma patients. ( Caprioli, J; Kwon, YH; Park, HJ; Weitzman, M, 1997) |
| "To investigate the incidence of complications reportedly caused by the use of 5-fluorouracil (5-FU) in glaucoma filtering surgery, we performed trabeculectomy with 5-FU on 57 eyes of 56 patients with advanced glaucoma." | 3.68 | Incidence of complications following 5-fluorouracil with trabeculectomies. ( Gieser, SC; Jacob, A; Raju, R; Sen, S; Thomas, R, 1993) |
| "Between 2/1991 and 1/1993 twenty-nine eyes of 11 female and 16 male patients with high-risk glaucoma (unsuccessful previous filtering surgery and a high risk of scarring) were treated with subconjunctival injections of 5-Fluorouracil after filtering surgery in the University Eye Hospital Düsseldorf." | 3.68 | [5-fluorouracil injection treatment after fistulating glaucoma operations]. ( Klüppel, M; Reinhard, T; Sundmacher, R, 1993) |
| "We measured aqueous flare in 16 glaucomatous eyes after trabeculectomy in which 5-fluorouracil (5-FU) or mitomycin C (MMC) had been used as an adjunctive therapy." | 3.68 | Anterior chamber reaction after mitomycin and 5-fluorouracil trabeculectomy: a comparative study. ( Jikihara, S; Kawase, K; Kitazawa, Y; Nishimura, K; Yamamoto, T, 1993) |
| "We studied 105 patients (105 eyes) operated on for glaucoma with adjunctive fluorouracil, who were followed up for 12 to 48 months (mean, 34." | 3.68 | Late complications after glaucoma filtering surgery with adjunctive 5-fluorouracil. ( Ophir, A; Ticho, U, 1993) |
| " These observations have lead to the widespread clinical use in humans of 5-fluorouracil and more recently mitomycin-C in glaucoma filtering surgery." | 3.68 | Antimetabolites in the surgical treatment of glaucomas. ( Van Caelenberghe, E; Van Oye, R, 1992) |
| "Twenty-one eyes of 18 patients with uncontrolled glaucoma and intraocular inflammatory disease had glaucoma filtering surgery with postoperative subconjunctival 5-fluorouracil (5-FU)." | 3.68 | Glaucoma filtering surgery with postoperative 5-fluorouracil in patients with intraocular inflammatory disease. ( Lowder, CY; Meisler, DM; Patitsas, CJ; Rockwood, EJ, 1992) |
| "Six patients, each with one eye that had previously undergone circular buckling surgery for the repair of retinal detachment before or followed by cataract extraction with or without intraocular lens implantation, underwent trabeculectomy with 5-fluorouracil (5-FU) for intractable glaucoma." | 3.68 | Trabeculectomy with 5-fluorouracil subsequent to circular buckling operation and cataract extraction. ( Ophir, A; Ticho, U, 1992) |
| "Trabeculectomy and subsequent subconjunctival injections of 5-fluorouracil (5-FU) were performed in four eyes (two children) with congenital glaucoma." | 3.68 | Subconjunctival injection of 5-fluorouracil following trabeculectomy for congenital and infantile glaucoma. ( Leiba, H; Oliver, M; Zalish, M, 1992) |
| "Repeated doses of 5mg of 5-fluorouracil (5-FU) were injected subconjunctivally in 25 poor-prognosis glaucomatous eyes after filtering surgery to prevent filtering bleb scarring." | 3.68 | Regulating the dose of 5-fluorouracil to prevent filtering bleb scarring. ( Ophir, A; Ticho, U, 1991) |
| "The effectiveness of trabeculectomy with adjunctive low-dose 5-fluorouracil (5-FU) as the initial surgical procedure in uncomplicated glaucoma was evaluated retrospectively in a consecutive series of 52 patients (mean follow-up, 18." | 3.68 | Initial 5-fluorouracil trabeculectomy in uncomplicated glaucoma. ( Liebmann, JM; Marmor, M; Nunez, J; Ritch, R; Wolner, B, 1991) |
| "The incidence of late-onset bleb-related endophthalmitis was evaluated retrospectively in 229 consecutive trabeculectomies performed with adjunctive 5-fluorouracil (5-FU) therapy." | 3.68 | Late bleb-related endophthalmitis after trabeculectomy with adjunctive 5-fluorouracil. ( Liebmann, JM; Marmor, M; Ritch, R; Sassani, JW; Speaker, M; Wolner, B, 1991) |
| "Nine patients (nine eyes) with iridocorneal endothelial (ICE) syndrome underwent trabeculectomy and received postoperative subconjunctival injections of 5-fluorouracil (5-FU) to enhance bleb formation (total 5-FU dose, 30-105 mg; mean, 53." | 3.68 | 5-Fluorouracil after trabeculectomy and the iridocorneal endothelial syndrome. ( Cristol, SM; Grajewski, AL; Parrish, RK; Wright, MM, 1991) |
| "We reviewed the records of 12 eyes of ten adult patients with inflammatory glaucoma who underwent trabeculectomy with the adjuvant use of 5-fluorouracil between January 1986 and January 1989." | 3.68 | Trabeculectomy with 5-fluorouracil for adult inflammatory glaucoma. ( Jabs, DA; Jampel, HD; Quigley, HA, 1990) |
| "5-Fluorouracil (5-FU) was injected subconjunctivally after glaucoma filtering surgery in a pilot study of eyes with poor surgical prognoses." | 3.67 | 5-fluorouracil and glaucoma filtering surgery. II. A pilot study. ( Anderson, DR; Gressel, MG; Heuer, DK; Hodapp, E; Palmberg, PF; Parrish, RK, 1984) |
| "The antimetabolite 5-fluorouracil (5-FU) was used as adjunctive treatment in glaucomatous eyes with poor prognoses undergoing filtering surgery." | 3.67 | Adjusting the dose of 5-fluorouracil after filtration surgery to minimize side effects. ( Weinreb, RN, 1987) |
| "We show that a 40-mg total dose of subconjunctival 5-fluorouracil after glaucoma filtering surgery can provide a success rate comparable to that demonstrated in prior studies employing a higher dose." | 3.67 | Low-dose 5-fluorouracil and glaucoma filtration surgery. ( Rabowsky, JH; Ruderman, JM, 1989) |
| "The effect of 5-fluorouracil (5-FU) subconjunctival injection on the bleb formation and intraocular pressure (IOP) following trabeculectomy was studied in 27 primary open-angle glaucoma patients (33 eyes) who had never been operated upon (25 eyes) or had undergone single trabeculectomy that failed to reduce IOP (8 eyes)." | 3.67 | Long-term results of 5-fluorouracil trabeculectomy for primary open-angle glaucoma. ( Kitazawa, Y; Shimizu, U; Taniguchi, T, 1989) |
| "A prospective, randomized, double-masked, and placebo-controlled study was performed to examine the effect of a localized and sustained delivery of 5-fluorouracil (5-FU) on the success of glaucoma filtration surgery in 18 rabbits." | 3.67 | Glaucoma filtration surgery in rabbits using bioerodible polymers and 5-fluorouracil. ( Anderson, PJ; de Kater, AW; Flores, RA; Hertzmark, E; Lee, DA; Leong, KW; Teekhasaenee, C, 1987) |
| "The effect of 5-fluorouracil (5-FU) subconjunctival injection on the bleb formation and intraocular pressure (IOP) following trabeculectomy was studied in 18 glaucoma patients (20 eyes) with poor surgical prognosis." | 3.67 | 5-Fluorouracil for trabeculectomy in glaucoma. ( Kitazawa, Y; Nakano, Y; Shirato, S; Taniguchi, T; Yamamoto, T, 1987) |
| " Although the success of trabeculectomy in lowering IOP is reduced when combined with phacoemulsification compared with trabeculectomy alone, this finding has to be set against the possible need for subsequent cataract surgery following trabeculectomy alone, which represents a second trip and expense for the patient and results in 10-61% failure of the trabeculectomy at one year post-cataract surgery." | 2.82 | Is Beta Radiation Better than 5 Flurouracil as an Adjunct for Trabeculectomy Surgery When Combined with Cataract Surgery? A Randomised Controlled Trial. ( Bowman, R; Cousens, S; Dhalla, K; Murdoch, I; Wood, M, 2016) |
| "68 eyes with chronic open angle glaucoma were included in a randomised trial of intraoperative 5-FU versus placebo." | 2.70 | A randomised trial of the effect of intraoperative 5-FU on the outcome of trabeculectomy in east Africa. ( Khaw, PT; Yorston, D, 2001) |
| "The use of low-dose subconjunctival 5-FU (mean dosage of 24." | 2.69 | Long-term outcome of primary glaucoma triple procedure with adjunctive 5-fluorouracil. ( Glover, BK; Hughes, BA; Juzych, MS; Kim, C; Kim, YY; O'Grady, JM; Ren, J; Shin, DH, 1998) |
| "Forty-two open angle glaucoma patients with uncontrolled intra-ocular pressure and with no risk factor of bleb fibrosis, underwent a NPDS." | 2.69 | [Deep nonpenetrating sclerectomy and open angle glaucoma. Intermediate results from the first operated patients]. ( Hamard, H; Hamard, P; Kopel, J; Plaza, L; Quesnot, S, 1999) |
| "5-Fluorouracil and MMC were found to be equally safe and effective adjuncts to primary trabeculectomy in the short- and medium-term postoperative periods." | 2.69 | Trabeculectomy with intraoperative mitomycin C versus 5-fluorouracil. Prospective randomized clinical trial. ( Baerveldt, GS; Budenz, DL; Chen, PP; Cohen, JS; Greenfield, DS; Mehta, K; Moster, MR; Shaikh, NM; Shaikh, S; Singh, K; Tsai, JC, 2000) |
| "Last controlled intraocular pressure is lower in C group patients (13." | 2.68 | [Intra- and postoperative use of 5-fluorouracil in the surgical treatment of refractory glaucoma]. ( Apatachioaie, I; Brănişteanu, D; Chiseliţă, D; Poiata, I; Rusu, V; Tătăruş, C, 1997) |
| "Late postoperative complications are similar with the exception of an increased incidence of Tenon cyst formation in the MMC-treated eyes." | 2.68 | Mitomycin C versus 5-fluorouracil in high-risk glaucoma filtering surgery. Extended follow-up. ( Bergstrom, TJ; Higginbotham, EJ; Johnson, AT; Katz, GJ; Lichter, PR; Musch, DC; Skuta, GL, 1995) |
| "Intraocular pressure was 20 mmHg or lower in 94% of 5-FU eyes and in 73% of control eyes (P < 0." | 2.67 | 5-Fluorouracil in initial trabeculectomy. A prospective, randomized, multicenter study. ( Gieser, DK; Goldenfeld, M; Krupin, T; Liebmann, JM; Ritch, R; Rosenberg, LF; Ruderman, JM; Wong, PC, 1994) |
| "Intraocular pressure was 20 mm Hg or lower in 24 eyes (96%) in the treatment group after mean follow-up of 17." | 2.67 | A randomized study of trabeculectomy and subconjunctival administration of fluorouracil in primary glaucomas. ( Ophir, A; Ticho, U, 1992) |
| "The risk of suprachoroidal hemorrhage was strongly associated with the level of the preoperative intraocular pressure." | 2.67 | Risk factors for suprachoroidal hemorrhage after filtering surgery. The Fluorouracil Filtering Surgery Study Group. ( , 1992) |
| "Raised intraocular pressure is a risk factor for glaucoma." | 2.52 | Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery. ( Cabourne, E; Clarke, JC; Evans, JR; Schlottmann, PG, 2015) |
| "In cases where such treatment fails, glaucoma-filtering surgery is considered, most commonly trabeculectomy surgery with variations in technique, for example, the type of conjunctival flap (fornix- or limbal-based)." | 2.52 | Fornix-based versus limbal-based conjunctival trabeculectomy flaps for glaucoma. ( Abdulaal, M; Al-Haddad, C; Al-Moujahed, A; Ervin, AM, 2015) |
| "The mean follow-up time after treatment for endophthalmitis was 6." | 2.41 | Delayed-onset bleb-associated endophthalmitis: clinical features and visual acuity outcomes. ( Budenz, DL; Flynn, HW; Scott, IU; Song, A, 2002) |
| "The use of antiscarring agents, particularly the antimetabolites 5-fluorouracil and mitomycin C, have revolutionized glaucoma surgery over the past decade." | 2.39 | Current techniques in wound healing modulation in glaucoma surgery. ( Khaw, PT; Migdal, CS, 1996) |
| "Mitomycin C seems to be a better treatment than 5 fluorouracil." | 2.38 | [Mitomycin C in glaucoma surgery]. ( Collignon-Brach, J, 1993) |
| " There was no significant adverse event for either group and no significant IOP difference in any of the observational periods between them (P=0." | 1.51 | Comparison of Efficacy and Safety of Bleb Needle Revision With and Without 5-Fluorouracil for Failing Trabeculectomy Bleb. ( Jeoung, JW; Kim, HJ; Kim, JS; Kim, YK; Na, KI; Park, KH, 2019) |
| "5-Fluorouracil (5-FU) has been well described for a failing trabeculectomy bleb, but not for aqueous shunts." | 1.46 | Use of subconjunctival injections of 5-fluorouracil to rescue and prolong intraocular pressure reduction for a failing Ahmed glaucoma implant. ( Kaplowitz, K; Khodadadeh, S; Lee, D; Tsai, JC; Wang, S, 2017) |
| "Intraocular pressure was 16 mmHg in the right and 36 mmHg in the left eye." | 1.40 | Iridocorneal endothelial syndrome. ( Akhtar, F; Ali, M; Saleem, AA, 2014) |
| "the Wuerzburg bleb classification score (WBCS) aims at an objective and standardized assessment of the developing filtering bleb after trabeculectomy, in order to detect and treat bleb scarring at the earliest possible stage of development." | 1.37 | The prognostic value of the wuerzburg bleb classification score for the outcome of trabeculectomy. ( Ellinger, P; Grehn, F; Guthoff, R; Kann, G; Klink, J; Klink, T, 2011) |
| " Based on the Wuerzburg bleb classification score (WBCS) for postoperative wound healing evaluation, 30 of these operations of group A (group B: n = 26) did not receive 5 FU postoperatively (controls), 67 (93) received up to 7 postoperative injections of 5 mg 5 FU (normal dosage group), and 72 (93) received more than 7 injections (high dosage group)." | 1.36 | [Corneal epitheliopathy following trabeculectomy with postoperative adjunctive 5-fluorouracil]. ( Geerling, G; Grehn, F; Klink, T; Reiter, C; Schultheiss, A; Wimmer, S, 2010) |
| "The area and the height of the bleb in the conjunctivae with radial incision (Ain and Hin, respectively) were compared with the area and the height of the bleb in the conjunctivae without radial incision (Ano and Hno, respectively)." | 1.35 | Restricted post-trabeculectomy bleb formation by conjunctival scarring. ( Inatani, M; Iwao, K; Ogata-Iwao, M; Takihara, Y; Tanihara, H, 2009) |
| "Juvenile-onset Open Angle Glaucoma (JOAG) has been proposed to be a small subset of Primary Open Angle Glaucoma (POAG) and on a continual spectrum of Primary Open Angle Glaucoma." | 1.35 | Bilateral ocular hypertension with rapidly progressive optic neuropathy in a teen. ( Byrne, E; Hua, LV; Yudcovitch, L, 2009) |
| "Others were encapsulated bleb 7." | 1.35 | Post-operative complication of trabeculectomy in Ibadan, Nigeria: outcome of 1-year follow-up. ( Ashaye, AO; Komolafe, OO, 2009) |
| "5-Fluorouracil (5-FU) has been used in patients with a pre-existing bleb, undergoing cataract surgery, but there are no published reports for or against its use in such cases." | 1.34 | Phacoemulsification in patients with previous trabeculectomy: role of 5-fluorouracil. ( Arora, S; Corridan, PG; Sharma, TK, 2007) |
| "Almost 49% of blebs underwent massage and a similar number required at least one suture removal, 31." | 1.34 | Frequency of bleb manipulations after trabeculectomy surgery. ( Alwitry, A; King, AJ; Moodie, J; Rotchford, AP, 2007) |
| " This study ascertained whether repeated injection of 5-FU has toxic effects on intraocular structures." | 1.33 | Do injections of 5-fluorouracil after trabeculectomy have toxic effects on the anterior segment? ( Allen, RC; Baynham, S; Lattanzio, FA; Samudre, S; Samuel, P; Sheppard, JD, 2005) |
| "Within this group, blebs were classified into three different categories according to their optical coherence tomography pattern: type A (featuring a thick wall and a single large fluid-filled space), type B (featuring a thin wall and multiple large fluid-filled spaces) and type C (featuring multiple, irregular and flattened fluid-filled spaces)." | 1.33 | Filtering blebs imaging by optical coherence tomography. ( Barboni, P; Savini, G; Zanini, M, 2005) |
| "5-Fluorouracil was safe and improved trabeculectomy survival." | 1.31 | The efficacy and safety of intraoperative and/or postoperative 5-fluorouracil in trabeculectomy and phacotrabeculectomy. ( Goldberg, I; Mohsin, M; Singh, RP, 2001) |
| "Intraocular pressure was significantly lower and an avascular area was more frequent in eyes with oozing or leak than in eyes without (P <." | 1.31 | Late-onset transconjunctival oozing and point leak of aqueous humor from filtering bleb after trabeculectomy. ( Araie, M; Matsuo, H; Shirato, S; Suzuki, Y; Tomidokoro, A, 2002) |
| "Mitomycin C was administered intraoperatively in the dose of 0." | 1.31 | [Antimetabolites in glaucoma surgery--long-term results]. ( Ferková, S; Jakabovicová, E; Michalíková, L; Strmen, P, 2002) |
| "Intraocular pressures were lower in the group that received MMC compared to the 5-FU group, but not in the group that did not receive antimetabolites, at all time intervals measured (P < ." | 1.30 | Comparison of phacotrabeculectomy with 5-fluorouracil, mitomycin-C, and without antifibrotic agents. ( Budenz, DL; Gordon, J; Keates, EU; Piltz-Seymour, J; Pyfer, M; Singh, K, 1999) |
| "A 71-year-old white woman with primary open angle glaucoma received trabeculectomy with antimetabolite." | 1.29 | Profound long-term hypotony without maculopathy after trabeculectomy with antimetabolite. ( Kaufman, PL; Kee, C, 1994) |
| "14 eyes of 14 patients with medically untreatable glaucoma and extremely bad surgical prognosis because of young age, secondary glaucomas or following previous surgery were treated by means of goniotrephination with a scleral flap and a fornix-based conjunctival flap." | 1.29 | [5-fluorouracil in goniotrepanation with poor prognosis. Results of 1-year follow-up]. ( Grehn, F; Pfeiffer, N, 1993) |
| " In this study, 5-Fluorouracil (5-FU), a halogenated pyrimidine analogue and a potent anti-mitotic agent, was applied for seven days after trabeculectomy in eighteen complicated and unsuccessful filtering glaucomas, at a daily dosage of 5 mg in the form of 0." | 1.29 | The role of 5-fluorouracil in complicated glaucomas. ( Das, S; Jilani, FA; Khan, AM, 1993) |
| "Complications included suprachoroidal hemorrhage in 7 (14%) of 49 eyes and intraoperative vitreous hemorrhage in 2." | 1.29 | Holmium laser sclerectomy. Success and complications. ( Bellows, AR; Hutchinson, BT; Lytle, R; Puliafito, CA; Schuman, JS; Stinson, WG, 1993) |
| "5-Fluorouracil (5-FU) has been used to improve the outcome of trabeculectomy in high-risk cases, employing a postoperative regimen of subconjunctival injections." | 1.29 | Low-dose perioperative 5-fluorouracil in trabeculectomy. ( Hugkulstone, CE; Vernon, SA, 1996) |
| " Our study may provide data on the appropriate dosage and indications for the use of this drug after glaucoma surgery." | 1.28 | Trabeculectomy with 5-fluorouracil. ( Iwata, K; Nanba, K; Sawaguchi, S; Watanabe, J, 1991) |
| "5-fluorouracil was injected subconjunctivally as an antiproliferative agent to prevent or decrease cell proliferation and scar formation." | 1.28 | External limbal sclerostomy with contact Nd:YAG laser versus surgical knife. ( Khoobehi, B; Oncel, M; Peyman, GA; Tawakol, ME, 1989) |
| "5-fluorouracil is an antimetabolite capable of inhibiting fibroblast proliferation." | 1.27 | 5-fluorouracil and glaucoma filtering surgery: I. An animal model. ( Folberg, R; Gressel, MG; Parrish, RK, 1984) |
| "Ater eight days, a hypertrophic scar formed, with the corneal endothelium extending over the scarred surface." | 1.27 | Q-switched neodymium-YAG laser trabeculopuncture in monkeys. ( Epstein, DL; Melamed, S; Pei, J; Puliafito, CA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (4.84) | 18.7374 |
| 1990's | 136 (43.87) | 18.2507 |
| 2000's | 91 (29.35) | 29.6817 |
| 2010's | 57 (18.39) | 24.3611 |
| 2020's | 11 (3.55) | 2.80 |
| Authors | Studies |
|---|---|
| Kandarakis, S | 1 |
| Kontaxakis, A | 1 |
| Doumazos, L | 1 |
| Petrou, P | 1 |
| Droutsas, K | 1 |
| Papaconstantinou, D | 1 |
| Georgalas, I | 1 |
| Al-Mugheiry, TS | 1 |
| Clark, A | 1 |
| Broadway, DC | 2 |
| Lee, JY | 1 |
| Wu, J | 1 |
| Liu, Y | 1 |
| Saraswathy, S | 1 |
| Zhou, L | 1 |
| Bu, Q | 1 |
| Su, Y | 1 |
| Choi, D | 1 |
| Park, E | 1 |
| Strohmaier, CA | 1 |
| Weinreb, RN | 3 |
| Hong, YK | 1 |
| Pan, X | 1 |
| Huang, AS | 1 |
| Wałek, E | 1 |
| Przeździecka-Dołyk, J | 1 |
| Helemejko, I | 1 |
| Misiuk-Hojło, M | 1 |
| Ang, BCH | 1 |
| Seen, S | 1 |
| Kumaran, A | 2 |
| De Leon, JMS | 1 |
| Seah, SKL | 1 |
| Foster, PJ | 6 |
| Gazzard, G | 7 |
| Htoon, HM | 4 |
| Khaw, PT | 16 |
| Aung, T | 9 |
| Husain, R | 7 |
| Halili, A | 1 |
| Kessel, L | 1 |
| Subhi, Y | 1 |
| Bach-Holm, D | 1 |
| Chen, X | 1 |
| Hong, Y | 1 |
| Zhang, C | 3 |
| Başer, EF | 1 |
| Seymenoğlu, RG | 1 |
| Kawashima, R | 1 |
| Matsushita, K | 1 |
| Kawasaki, R | 1 |
| Nishida, K | 1 |
| Zhao, X | 1 |
| Liu, S | 1 |
| Han, Y | 3 |
| Wang, Y | 2 |
| Lin, Q | 1 |
| Kaplowitz, K | 2 |
| Khodadadeh, S | 1 |
| Wang, S | 1 |
| Lee, D | 1 |
| Tsai, JC | 3 |
| Lindemann, F | 1 |
| Plange, N | 2 |
| Kuerten, D | 1 |
| Schimitzek, H | 1 |
| Koutsonas, A | 2 |
| Shihadeh, W | 1 |
| Massad, I | 1 |
| Khader, Y | 1 |
| Al-Rawi, A | 1 |
| Alshalakhti, T | 1 |
| Vinod, K | 2 |
| Gedde, SJ | 2 |
| Feuer, WJ | 3 |
| Panarelli, JF | 2 |
| Chang, TC | 1 |
| Chen, PP | 3 |
| Parrish, RK | 5 |
| Quaranta, L | 3 |
| Katsanos, A | 2 |
| Legramandi, L | 1 |
| Riva, I | 1 |
| Wang, J | 2 |
| Gao, H | 1 |
| Wang, X | 1 |
| Wu, M | 1 |
| Guo, B | 2 |
| Liu, C | 1 |
| Liu, W | 2 |
| Bhullar, GK | 1 |
| Skalicky, SE | 1 |
| Lew, HR | 1 |
| Pimentel, E | 1 |
| Schmidt, J | 1 |
| Elgin, U | 2 |
| Sen, E | 1 |
| Çolak, S | 1 |
| Yılmazbas, P | 1 |
| Koike, KJ | 1 |
| Chang, PT | 1 |
| Arnljots, TS | 1 |
| Kasina, R | 1 |
| Bykov, VJN | 1 |
| Economou, MA | 1 |
| Rabiolo, A | 1 |
| Marchese, A | 1 |
| Bettin, P | 2 |
| Monteduro, D | 1 |
| Galasso, M | 1 |
| Dolci, MP | 1 |
| Di Matteo, F | 1 |
| Fiori, M | 2 |
| Ciampi, C | 1 |
| Bandello, F | 1 |
| Swann, FB | 1 |
| Singh, S | 1 |
| Blake, D | 1 |
| John, V | 1 |
| Le, C | 1 |
| Fullerton, M | 1 |
| Margo, C | 1 |
| Zhang, Z | 1 |
| Muddasani, N | 1 |
| Wall, J | 1 |
| Satija, C | 1 |
| Greenberg, E | 1 |
| Mancera, N | 1 |
| Zurakowski, D | 1 |
| Ayyala, RS | 1 |
| Kim, JS | 1 |
| Kim, HJ | 1 |
| Na, KI | 1 |
| Kim, YK | 1 |
| Park, KH | 1 |
| Jeoung, JW | 1 |
| Lin, M | 1 |
| Alizadeh, R | 1 |
| Law, SK | 1 |
| Wong, MH | 1 |
| Ang, BC | 1 |
| Wong, TT | 5 |
| Oen, FT | 4 |
| Seah, SK | 5 |
| Tatham, A | 1 |
| Sarodia, U | 1 |
| Karwatowski, W | 1 |
| Suh, W | 1 |
| Kee, C | 2 |
| Wu, X | 1 |
| Sun, Y | 1 |
| Zhang, Y | 1 |
| Zhang, H | 1 |
| Zhao, J | 1 |
| Suzuki, R | 2 |
| Susanna, R | 3 |
| De Fendi, LI | 1 |
| Arruda, GV | 1 |
| Scott, IU | 2 |
| Paula, JS | 1 |
| Remky, A | 1 |
| De Moraes, CG | 1 |
| Alencar, LM | 1 |
| Ritch, R | 9 |
| Saleem, AA | 1 |
| Ali, M | 1 |
| Akhtar, F | 1 |
| Menda, SA | 1 |
| Lowry, EA | 1 |
| Porco, TC | 2 |
| Stamper, RL | 2 |
| Rubin, MR | 1 |
| Zheng, L | 1 |
| Arvind, H | 1 |
| Wechsler, D | 1 |
| Cabourne, E | 1 |
| Clarke, JC | 1 |
| Schlottmann, PG | 1 |
| Evans, JR | 1 |
| Bi, XZ | 1 |
| Pan, WH | 1 |
| Yu, XP | 1 |
| Song, ZM | 1 |
| Ren, ZJ | 1 |
| Sun, M | 1 |
| Li, CH | 1 |
| Nan, KH | 1 |
| Al-Haddad, C | 1 |
| Abdulaal, M | 1 |
| Al-Moujahed, A | 1 |
| Ervin, AM | 1 |
| Floriani, I | 1 |
| Hollander, L | 1 |
| Poli, D | 1 |
| Konstas, AG | 1 |
| Huang, G | 1 |
| Sidoti, PA | 2 |
| Cui, QN | 1 |
| Hsia, YC | 1 |
| Lin, SC | 2 |
| Rose-Nussbaumer, J | 1 |
| Mehta, N | 1 |
| Naseri, A | 1 |
| Wilson, ME | 1 |
| Gupta, P | 1 |
| Tran, KV | 1 |
| Arora, KS | 1 |
| Lee, CH | 1 |
| Chang, DS | 1 |
| Friedman, DS | 3 |
| Dhalla, K | 1 |
| Cousens, S | 1 |
| Bowman, R | 2 |
| Wood, M | 2 |
| Murdoch, I | 1 |
| Lorenz, K | 1 |
| Wasielica-Poslednik, J | 1 |
| Bell, K | 1 |
| Renieri, G | 1 |
| Keicher, A | 1 |
| Ruckes, C | 1 |
| Pfeiffer, N | 2 |
| Thieme, H | 1 |
| Minckler, DS | 3 |
| Francis, BA | 1 |
| Hodapp, EA | 1 |
| Jampel, HD | 3 |
| Samples, JR | 1 |
| Smith, SD | 1 |
| Singh, K | 6 |
| Alvarado, JA | 1 |
| Hollander, DA | 1 |
| Juster, RP | 2 |
| Lee, LC | 1 |
| Polak, MB | 1 |
| Valamanesh, F | 1 |
| Felt, O | 1 |
| Torriglia, A | 1 |
| Jeanny, JC | 1 |
| Bourges, JL | 1 |
| Rat, P | 1 |
| Thomas-Doyle, A | 1 |
| BenEzra, D | 1 |
| Gurny, R | 2 |
| Behar-Cohen, F | 2 |
| Taube, AB | 1 |
| Niemelä, P | 1 |
| Alm, A | 2 |
| Cui, LJ | 1 |
| Sun, NX | 1 |
| Li, XH | 1 |
| Huang, J | 1 |
| Yang, JG | 1 |
| Palanca-Capistrano, AM | 2 |
| Hall, J | 1 |
| Cantor, LB | 3 |
| Morgan, L | 1 |
| Hoop, J | 2 |
| WuDunn, D | 3 |
| Zarkovic, A | 1 |
| Chow, K | 1 |
| Mora, JS | 2 |
| Memarzadeh, F | 1 |
| Varma, R | 1 |
| Lin, LT | 1 |
| Parikh, JG | 1 |
| Dustin, L | 1 |
| Alcaraz, A | 1 |
| Eliott, D | 1 |
| Devereux, JG | 2 |
| Minassian, D | 1 |
| Tan, SB | 1 |
| Chew, PT | 3 |
| Iwao, K | 1 |
| Inatani, M | 1 |
| Ogata-Iwao, M | 1 |
| Takihara, Y | 1 |
| Tanihara, H | 1 |
| Anand, N | 4 |
| Khan, A | 1 |
| Kotecha, A | 1 |
| Spratt, A | 1 |
| Bunce, C | 5 |
| Garway-Heath, DF | 1 |
| Viswanathan, A | 1 |
| Hua, LV | 1 |
| Byrne, E | 1 |
| Yudcovitch, L | 1 |
| Klink, T | 2 |
| Kann, G | 1 |
| Ellinger, P | 1 |
| Klink, J | 1 |
| Grehn, F | 5 |
| Guthoff, R | 1 |
| Jalil, A | 1 |
| Au, L | 1 |
| Khan, I | 1 |
| Ashworth, J | 1 |
| Lloyd, IC | 1 |
| Biswas, S | 1 |
| YANG, LQ | 1 |
| LAN, YQ | 1 |
| GUO, H | 1 |
| CHENG, LZ | 1 |
| FAN, JZ | 1 |
| CAI, X | 1 |
| ZHANG, LM | 1 |
| CHEN, RF | 1 |
| ZHOU, HS | 1 |
| Reiter, C | 1 |
| Wimmer, S | 1 |
| Schultheiss, A | 1 |
| Geerling, G | 1 |
| Tan, YL | 1 |
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| Perera, SA | 1 |
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| Day, AC | 1 |
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| Liang, S | 1 |
| Lin, ZJ | 1 |
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| Shafi, F | 1 |
| Agrawal, P | 1 |
| Holder, R | 1 |
| Sung, V | 1 |
| Narayanaswamy, AK | 1 |
| Lee, K | 1 |
| Zhen, M | 1 |
| Chua, J | 1 |
| Chai, SM | 1 |
| Boey, PY | 1 |
| Zheng, C | 1 |
| Venkatraman, S | 1 |
| Salim, S | 1 |
| Chua, BE | 1 |
| Nguyen, DQ | 1 |
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| Ruddle, JB | 1 |
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| Gupta, V | 1 |
| Coote, MA | 1 |
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| Mermoud, A | 3 |
| Congdon, NG | 1 |
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| Ramakrishnan, R | 1 |
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| Quigley, HA | 2 |
| Simsek, T | 1 |
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| Griffiths, M | 1 |
| Zahid, S | 1 |
| Musch, DC | 4 |
| Niziol, LM | 1 |
| Lichter, PR | 4 |
| de Klerk, TA | 1 |
| Chaudhry, N | 1 |
| Moriarty, AP | 1 |
| Ceballos, EM | 1 |
| Beck, AD | 1 |
| Lynn, MJ | 1 |
| Dickens, CJ | 4 |
| Iwach, AG | 5 |
| Hoskins, HD | 5 |
| Hetherington, J | 2 |
| Wong, PC | 4 |
| Klufas, MT | 1 |
| Leong, CJ | 1 |
| Nguyen, N | 2 |
| Alvi, NP | 1 |
| Finley, C | 1 |
| Lakhani, V | 1 |
| Burnstein, A | 1 |
| Knotts, SL | 1 |
| Lubomski, LH | 1 |
| Kempen, JH | 1 |
| Quigley, H | 1 |
| Congdon, N | 1 |
| Levkovitch-Verbin, H | 1 |
| Robinson, KA | 1 |
| Bass, EB | 1 |
| Durak, I | 1 |
| Ozbek, Z | 1 |
| Yaman, A | 1 |
| Soylev, M | 1 |
| Cingil, G | 1 |
| Jordan, JF | 1 |
| Carassa, RG | 1 |
| Brancato, R | 1 |
| Oen, F | 1 |
| Chew, P | 2 |
| Seah, S | 1 |
| Detry-Morel, M | 3 |
| De Temmerman, S | 1 |
| Akarsu, C | 1 |
| Onol, M | 1 |
| Hasanreisoglu, B | 1 |
| Aydin, A | 1 |
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| Mielke, C | 1 |
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| Serle, JB | 1 |
| Tello, CA | 1 |
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| Jordanova, VD | 1 |
| Vukosavljević, M | 1 |
| Dzajkovska, E | 1 |
| Ren, ZQ | 1 |
| Qiao, RH | 1 |
| Arora, S | 2 |
| Clowes, M | 1 |
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| Corridan, PG | 2 |
| Shingleton, BJ | 1 |
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| Kasner, O | 2 |
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| Lago-Llinás, MD | 1 |
| Reinthal, EK | 1 |
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| Bartz-Schmidt, KU | 1 |
| Mehta, JS | 1 |
| Maurino, V | 1 |
| Patel, H | 1 |
| Kirwin, J | 1 |
| Murdoch, IE | 1 |
| Chang, L | 1 |
| Moseley, M | 1 |
| Woodruff, S | 1 |
| Bentley, C | 1 |
| Bloom, P | 3 |
| King, AJ | 2 |
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| Alwitry, A | 1 |
| Moodie, J | 1 |
| Chakraborty, D | 1 |
| Dutta Choudhury, B | 1 |
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| Komolafe, OO | 1 |
| Heuer, DK | 4 |
| Gressel, MG | 2 |
| Hodapp, E | 1 |
| Palmberg, PF | 3 |
| Anderson, DR | 1 |
| Folberg, R | 1 |
| Vernon, SA | 2 |
| Spencer, AF | 1 |
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| Ott, JP | 1 |
| Ferrigno, G | 1 |
| Sciacca, S | 1 |
| Reibaldi, A | 1 |
| Gray, TB | 1 |
| Joos, KM | 1 |
| Bueche, MJ | 1 |
| Grajewski, AL | 2 |
| Kaufman, PL | 1 |
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| Jacob, A | 1 |
| Raju, R | 1 |
| Gieser, SC | 1 |
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| Goldenfeld, M | 2 |
| Krupin, T | 2 |
| Ruderman, JM | 5 |
| Rosenberg, LF | 2 |
| Liebmann, JM | 8 |
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| Stürmer, J | 1 |
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| Hitchings, RA | 3 |
| Reinhard, T | 1 |
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| Oh, Y | 1 |
| Katz, LJ | 2 |
| Spaeth, GL | 4 |
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| Longstaff, S | 1 |
| Collignon-Brach, J | 1 |
| Doyle, JW | 5 |
| Sherwood, MB | 4 |
| McGrory, S | 1 |
| Smith, MF | 7 |
| O'Grady, JM | 2 |
| Juzych, MS | 3 |
| Shin, DH | 4 |
| Lemon, LC | 1 |
| Swendris, RP | 2 |
| Egbert, PR | 3 |
| Williams, AS | 2 |
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| Egbert, TB | 1 |
| Bluestein, EC | 1 |
| Stewart, WC | 2 |
| Hurvitz, LM | 1 |
| Khan, AM | 1 |
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| Das, S | 1 |
| Ophir, A | 7 |
| Ticho, U | 7 |
| Khatana, AK | 2 |
| Parrow, KA | 1 |
| Stinson, WG | 1 |
| Hutchinson, BT | 1 |
| Bellows, AR | 1 |
| Puliafito, CA | 2 |
| Lytle, R | 1 |
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| Sandramouli, S | 1 |
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| Araie, M | 8 |
| Shimizu, K | 1 |
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| Shirato, S | 10 |
| Yamagami, J | 1 |
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| Park, HJ | 3 |
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| Zimmerman, TJ | 1 |
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| Menage, MJ | 1 |
| Budenz, D | 2 |
| Tezel, G | 1 |
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| Kass, MA | 1 |
| Wax, MB | 1 |
| Gallenga, PE | 2 |
| Mastropasqua, L | 2 |
| Carpineto, P | 2 |
| Ciancaglini, M | 2 |
| Zuppardi, E | 2 |
| Colotto, A | 1 |
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| Chua, JK | 1 |
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| Ren, J | 1 |
| Kim, YY | 2 |
| Hughes, BA | 1 |
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| Glover, BK | 1 |
| Choi, JC | 1 |
| Morinelli, EN | 1 |
| Lee, PP | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Macular Thickness in Patients With Glaucoma in Use of Topical Prostaglandin Analogue Undergoing Trabeculectomy With Mitomycin C[NCT06000280] | 37 participants (Actual) | Interventional | 2021-01-04 | Completed | |||
| Early Transconjunctival Needling Revision With 5-fluorouracil Versus Medical Treatment in Encapsulated Blebs: a 12-month Prospective Study[NCT01887223] | Phase 2 | 40 participants (Actual) | Interventional | 2010-05-31 | Completed | ||
| Clinical Efficacy and Safety of Minimally Invasive Glaucoma Surgery on Chinese Primary Angle Closure Glaucoma[NCT02964676] | 246 participants (Anticipated) | Interventional | 2017-01-31 | Not yet recruiting | |||
| Efficacy and Safety of Trabeculectomy With Subconjunctival Bevacizumab Versus Trabeculectomy With Mitomycin C.[NCT01310764] | 36 participants (Actual) | Interventional | 2009-04-30 | Completed | |||
| Intermediate Term Outcomes of Intraoperative 5-Fluorouracil Versus Mitomycin c in Trabeculectomy Surgery.[NCT00346489] | Phase 4 | 70 participants | Interventional | 2004-09-30 | Completed | ||
| Comparison of Combined Phacotrabeculectomy and Trabeculectomy Only in the Treatment of Primary Angle-closure Glaucoma[NCT01298635] | 31 participants (Actual) | Interventional | 2005-01-31 | Completed | |||
| Anterior Segment Optical Coherence Tomography Findings in Patients With Ahmed Glaucoma Drainage Implants With Either a Pericardial Patch Graft and Fibrin Tissue Glue or a Partial-Thickness Scleral Flap and Conventional Sutures[NCT00453024] | Phase 2 | 40 participants (Anticipated) | Interventional | 2007-02-28 | Recruiting | ||
| Intraocular Pressure Control Following One Site Versus Two Site Combined Phacoemulsification/IOL And Trabeculectomy[NCT00695747] | 95 participants (Actual) | Interventional | 1998-01-31 | Completed | |||
| [NCT00000122] | Phase 3 | 0 participants | Interventional | 1985-09-30 | Completed | ||
| [NCT00000149] | Phase 3 | 0 participants | Interventional | 1993-10-31 | Active, not recruiting | ||
| Phacoemulsification Combined With Trabeculectomy Versus Phacoemulsification Combined With Trabeculotomy for Treatment of Chronic Angle Closure Glaucoma[NCT04683055] | 50 participants (Actual) | Interventional | 2020-10-28 | Completed | |||
| Glaucoma Eye Drop Instillation: Impact of Education[NCT01416415] | 119 participants (Actual) | Interventional | 2011-08-31 | Terminated (stopped due to Not practical to continue due interim results) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 reviews available for fluorouracil and Intraocular Pressure
| Article | Year |
|---|---|
Needling after trabeculectomy - does augmentation by anti-metabolites provide better outcomes and is Mitomycin C better than 5-Fluoruracil? A systematic review with network meta-analyses.
Topics: Fluorouracil; Glaucoma; Humans; Immunosuppressive Agents; Intraocular Pressure; Mitomycin; Network M | 2020 |
Is mytomicyn better than 5-fluorouracil as antimetabolite in trabeculectomy for glaucoma?
Topics: Antimetabolites; Cicatrix; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Mitomycin; Randomiz | 2018 |
Trabeculectomy: A Brief History and Review of Current Trends.
Topics: Angiogenesis Inhibitors; Fluorouracil; Glaucoma; History, 20th Century; History, 21st Century; Human | 2018 |
Mitomycin C versus 5-fluorouracil as an adjunctive treatment for trabeculectomy: a meta-analysis of randomized clinical trials.
Topics: Alkylating Agents; Antimetabolites; Chemotherapy, Adjuvant; Epithelium, Corneal; Fluorouracil; Glauc | 2013 |
Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery.
Topics: Antimetabolites; Chemotherapy, Adjuvant; Cicatrix; Fluorouracil; Glaucoma; Humans; Intraocular Press | 2015 |
Fornix-based versus limbal-based conjunctival trabeculectomy flaps for glaucoma.
Topics: Antihypertensive Agents; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Limbus Corneae; Mitom | 2015 |
Intraoperative mitomycin C versus intraoperative 5-fluorouracil for trabeculectomy: a systematic review and meta-analysis.
Topics: Controlled Clinical Trials as Topic; Fluorouracil; Humans; Intraocular Pressure; Intraoperative Care | 2012 |
Current variations of glaucoma filtration surgery.
Topics: Alkylating Agents; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Mitomycin; Surgical Flaps; | 2012 |
Deep sclerectomy.
Topics: Conjunctiva; Fibrosis; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Immunosuppressive Agents; | 2012 |
Effect of technique on intraocular pressure after combined cataract and glaucoma surgery: An evidence-based review.
Topics: Antimetabolites, Antineoplastic; Cataract; Cataract Extraction; Evidence-Based Medicine; Fluorouraci | 2002 |
[Modulation of wound healing in filtration surgery for glaucoma].
Topics: Adolescent; Adult; Age Factors; Alkylating Agents; Animals; Antimetabolites; Child; Filtering Surger | 2003 |
[Mitomycin C in glaucoma surgery].
Topics: Adult; Aged; Aged, 80 and over; Cicatrix; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Midd | 1993 |
Wound healing modulation in glaucoma filtration surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Fluorouracil; Glaucoma; Humans; Intraocular | 1993 |
Trabeculectomy with intraoperative sponge 5-fluorouracil.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Chemotherapy, Adjuvant; Child; Child, P | 1996 |
Trabeculectomy with intraoperative sponge 5-fluorouracil in Afro-Caribbeans.
Topics: Administration, Topical; Antimetabolites; Black People; Case-Control Studies; Female; Fluorouracil; | 1997 |
Surgical consequences in coexisting cataract and glaucoma.
Topics: Cataract; Cataract Extraction; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Lenses, Intraoc | 1995 |
Current techniques in wound healing modulation in glaucoma surgery.
Topics: Animals; Antimetabolites; Cataract Extraction; Cicatrix; Filtering Surgery; Fluorouracil; Glaucoma; | 1996 |
The use of antimetabolites with trabeculectomy: a critical appraisal.
Topics: Antimetabolites; Combined Modality Therapy; Delivery of Health Care; Fluorouracil; Glaucoma; Humans; | 2001 |
Delayed-onset bleb-associated endophthalmitis: clinical features and visual acuity outcomes.
Topics: Adult; Aged; Aged, 80 and over; Anterior Chamber; Bacteria; Endophthalmitis; Eye Infections, Bacteri | 2002 |
72 trials available for fluorouracil and Intraocular Pressure
| Article | Year |
|---|---|
Assessing safety and success after using bevacizumab, 5-fluorouracil or placebo in primary trabeculectomy. A prospective randomized placebo controlled 1-year follow-up study.
Topics: Angiogenesis Inhibitors; Bevacizumab; Fluorouracil; Follow-Up Studies; Humans; Intraocular Pressure; | 2022 |
Fluorouracil Filtering Surgery Study One-Year Follow-up.
Topics: Aged; Conjunctiva; Dose-Response Relationship, Drug; Female; Filtering Surgery; Fluorouracil; Follow | 2018 |
Longitudinal Changes in Bleb Height, Vascularity, and Conjunctival Microcysts After Trabeculectomy.
Topics: Aged; Blister; Combined Modality Therapy; Conjunctiva; Conjunctival Diseases; Cysts; Female; Fluorou | 2018 |
The Singapore 5-fluorouracil trial: intraocular pressure outcomes at 8 years.
Topics: Antihypertensive Agents; Antimetabolites; Combined Modality Therapy; Double-Blind Method; Fluorourac | 2013 |
The effect of bevacizumab on the outcome of trabeculectomy with 5-Fluorouracil.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Bevaciz | 2013 |
Early transconjunctival needling revision with 5-fluorouracil versus medical treatment in encapsulated blebs: a 12-month prospective study.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Blister; Conjunctiva; Female; Fluorouracil; Glaucom | 2013 |
Is Beta Radiation Better than 5 Flurouracil as an Adjunct for Trabeculectomy Surgery When Combined with Cataract Surgery? A Randomised Controlled Trial.
Topics: Aged; Beta Particles; Cataract Extraction; Female; Fluorouracil; Follow-Up Studies; Humans; Intraocu | 2016 |
Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma.
Topics: Acetazolamide; Aged; Antihypertensive Agents; Dexamethasone; Drug Combinations; Female; Fluorouracil | 2017 |
Long-term outcomes of intraoperative 5-fluorouracil versus intraoperative mitomycin C in primary trabeculectomy surgery.
Topics: Administration, Topical; Alkylating Agents; Antihypertensive Agents; Antimetabolites; Combined Modal | 2009 |
The singapore 5-Fluorouracil trabeculectomy study: effects on intraocular pressure control and disease progression at 3 years.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Disease Progression; Double | 2009 |
Optic disc and visual field changes after trabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Combined Modality Therapy; Disease Progression; Dou | 2009 |
Central corneal thickness and glaucoma in East Asian people.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alkylating Agents; Asian People; Case-Control Studies; Cornea | 2011 |
Cataract surgery after trabeculectomy: the effect on trabeculectomy function.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Female; Fluorouracil; Follow-Up Studies; Glaucoma | 2012 |
Randomized, controlled trial of a sustained delivery formulation of 5-fluorouracil for the treatment of failing blebs.
Topics: Aged; Aqueous Humor; Conjunctiva; Delayed-Action Preparations; Female; Fluorouracil; Glaucoma; Human | 2012 |
Bleb vascularity following post-trabeculectomy subconjunctival bevacizumab: a pilot study.
Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antimetabolites; Bevacizumab; Conj | 2012 |
A study of initial therapy for glaucoma in southern India: India Glaucoma Outcomes and Treatment (INGOT) Study.
Topics: Aged; Antihypertensive Agents; Antimetabolites, Antineoplastic; Brimonidine Tartrate; Drug Combinati | 2012 |
Comparison of needle revision with subconjunctival bevacizumab and 5-fluorouracil injection of failed trabeculectomy blebs.
Topics: Antibodies, Monoclonal, Humanized; Bevacizumab; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans; | 2012 |
Risk of endophthalmitis and other long-term complications of trabeculectomy in the Collaborative Initial Glaucoma Treatment Study (CIGTS).
Topics: Antimetabolites; Cataract Extraction; Endophthalmitis; Fluorouracil; Follow-Up Studies; Glaucoma, Op | 2013 |
A prospective randomized trial comparing intraoperative 5-fluorouracil vs mitomycin C in primary trabeculectomy.
Topics: Antimetabolites; Double-Blind Method; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Intraope | 2002 |
Viscocanalostomy versus trabeculectomy in white adults affected by open-angle glaucoma: a 2-year randomized, controlled trial.
Topics: Aged; Anterior Eye Segment; Conjunctiva; Exfoliation Syndrome; Female; Fluorouracil; Glaucoma, Open- | 2003 |
Intraocular pressure and visual field loss in primary angle closure and primary open angle glaucomas.
Topics: Antimetabolites; Cross-Sectional Studies; Female; Fluorouracil; Glaucoma, Angle-Closure; Glaucoma, O | 2003 |
A randomised, prospective study comparing trabeculectomy with viscocanalostomy with adjunctive antimetabolite usage for the management of open angle glaucoma uncontrolled by medical therapy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Blister; Cataract; Female; Filtering Surgery; Fluor | 2004 |
[Intra- and postoperative use of 5-fluorouracil in the surgical treatment of refractory glaucoma].
Topics: Antimetabolites; Conjunctiva; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Injections; Intraoc | 1997 |
Comparison of 1-site versus 2-site phacotrabeculectomy.
Topics: Antihypertensive Agents; Case-Control Studies; Cataract; Fluorouracil; Follow-Up Studies; Glaucoma; | 2006 |
The role of antimetabolites in filtration surgery for neovascular glaucoma: intermediate-term follow-up.
Topics: Adult; Aged; Antimetabolites; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Gl | 2007 |
5-Fluorouracil in initial trabeculectomy. A prospective, randomized, multicenter study.
Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Exfoliation Syndrome; Female; Fluorouracil; Foll | 1994 |
5-Fluorouracil after primary combined filtration surgery.
Topics: Aged; Cataract; Cataract Extraction; Combined Modality Therapy; Female; Fluorouracil; Glaucoma, Open | 1994 |
Update of the subconjunctival THC:YAG (holmium) laser sclerostomy ab externo clinical trial: 30-month report.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Fluorouracil; Follow-Up Studies; Glaucoma | 1994 |
Risk factors for the development of encapsulated filtering blebs. The role of surgical glove powder and 5-fluorouracil.
Topics: Adult; Aged; Aged, 80 and over; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Gloves, Surgical; | 1994 |
Trabeculectomy, phacoemulsification, and posterior chamber lens implantation with and without 5-fluorouracil.
Topics: Aged; Cataract Extraction; Chronic Disease; Conjunctiva; Fluorouracil; Follow-Up Studies; Glaucoma, | 1993 |
A prospective trial of intraoperative fluorouracil during trabeculectomy in a black population.
Topics: Adult; Aged; Aged, 80 and over; Black People; Female; Fluorouracil; Follow-Up Studies; Ghana; Glauco | 1993 |
Three-year follow-up of the Fluorouracil Filtering Surgery Study.
Topics: Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Postoperative Care; Surviva | 1993 |
[A five-year follow-up of the effect of postoperative 5-fluorouracil subconjunctival injections on the surgical outcome of trabeculectomy].
Topics: Adult; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Injections; Intraocul | 1993 |
Five-year follow-up of the Fluorouracil Filtering Surgery Study. The Fluorouracil Filtering Surgery Study Group.
Topics: Cataract Extraction; Chemotherapy, Adjuvant; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Immu | 1996 |
Results of intraoperative 5-fluorouracil in patients undergoing trabeculectomy--pilot trial.
Topics: Adolescent; Adult; Aged; Antimetabolites; Chemotherapy, Adjuvant; Conjunctiva; Female; Fluorouracil; | 1996 |
Temporal corneal phacoemulsification combined with superior trabeculectomy: a controlled study.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cataract; Cornea; Female; Fluorouracil; Glaucoma; Hum | 1996 |
Short-term results of initial trabeculectomy with intraoperative or postoperative 5-fluorouracil for primary glaucomas.
Topics: Antimetabolites; Chemotherapy, Adjuvant; Conjunctiva; Female; Fluorouracil; Glaucoma, Angle-Closure; | 1996 |
5-fluorouracil in combined trabeculectomy and clear-cornea phacoemulsification with posterior chamber intraocular lens implantation. A one-year randomized, controlled clinical trial.
Topics: Antimetabolites; Cataract; Cornea; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; In | 1997 |
Mitomycin C versus 5-fluorouracil in high-risk glaucoma filtering surgery. Extended follow-up.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Female; Filter | 1995 |
Trabeculectomy with intraoperative 5-fluorouracil vs mitomycin C.
Topics: Antimetabolites; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Intraoperative Care; | 1997 |
Short-term results of initial trabeculectomy with intraoperative or postoperative 5-fluorouracil for primary glaucomas.
Topics: Administration, Topical; Antimetabolites; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Angle-C | 1997 |
Risk of hypotony after primary trabeculectomy with antifibrotic agents in a black west African population.
Topics: Fluorouracil; Follow-Up Studies; Ghana; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Intraope | 1998 |
Delayed postoperative use of 5-fluorouracil in primary open angle glaucoma.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Fluorouracil; Follow-Up Studies; Glauc | 1997 |
Long-term outcome of primary glaucoma triple procedure with adjunctive 5-fluorouracil.
Topics: Aged; Chemotherapy, Adjuvant; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; | 1998 |
Delayed post-operative use of 5-fluorouracil as an adjunct in medically uncontrolled open angle glaucoma.
Topics: Aged; Aged, 80 and over; Antimetabolites; Chemotherapy, Adjuvant; Drug Administration Schedule; Fema | 1998 |
Oral prednisone in guarded filtration procedures supplemented with antimetabolites.
Topics: Administration, Oral; Aged; Chemotherapy, Adjuvant; Double-Blind Method; Female; Filtering Surgery; | 1999 |
A randomized phase II trial of interferon-alpha2b versus 5-fluorouracil after trabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Cataract; Cataract Extraction; Connective Tissue; Double-Blind Metho | 1999 |
Fornix-based versus limbal-based conjunctival flaps in initial trabeculectomy with postoperative 5-fluorouracil: four-year follow-up findings.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Conjunctiva; Fluorouracil; Follow-Up Studies; Glauc | 1999 |
[Deep nonpenetrating sclerectomy and open angle glaucoma. Intermediate results from the first operated patients].
Topics: Administration, Topical; Aged; Collagen; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Ang | 1999 |
Combined cataract and glaucoma surgery: trabeculectomy versus endoscopic laser cycloablation.
Topics: Cataract; Ciliary Body; Endoscopy; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intrao | 1999 |
Low-dose 5-fluorouracil trabeculectomy as initial surgery in uncomplicated glaucoma: long-term followup.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Female; Fluorouracil; Follow-Up | 2000 |
Trabeculectomy with intraoperative mitomycin C versus 5-fluorouracil. Prospective randomized clinical trial.
Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Drug Evaluation; Female; Fluorouracil | 2000 |
Randomized, controlled study of low-dose 5-fluorouracil in primary trabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Chemotherapy, Adjuvant; Conjunctiva; Drug Evaluatio | 2000 |
Efficacy of sulodexide as adjunct in trabeculectomy. A two-year randomized clinical study.
Topics: Chemotherapy, Adjuvant; Fibrinolytic Agents; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; | 2000 |
A randomised trial of the effect of intraoperative 5-FU on the outcome of trabeculectomy in east Africa.
Topics: Antimetabolites; Chronic Disease; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Int | 2001 |
Prognosis and risk factors for early postoperative wound leaks after trabeculectomy with and without 5-fluorouracil.
Topics: Antimetabolites; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Injections; | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cataract; Female; Fluorouracil; Follow-Up Studies; Glaucom | 2001 |
Single intraoperative application of 5-Fluorouracil versus placebo in low-risk trabeculectomy surgery: a randomized trial.
Topics: Aged; Antimetabolites; Chemotherapy, Adjuvant; Conjunctiva; Double-Blind Method; Female; Fluorouraci | 2001 |
A randomised, prospective study comparing trabeculectomy augmented with antimetabolites with a viscocanalostomy technique for the management of open angle glaucoma uncontrolled by medical therapy.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Combined Modality Therapy; Female; Fluorouracil; Fo | 2002 |
Long-term results of trabeculectomy with collagen sponge implant containing low-dose antimetabolite.
Topics: Adult; Aged; Biological Dressings; Bleomycin; Collagen; Drug Implants; Female; Fluorouracil; Glaucom | 1992 |
Daunorubicin versus 5-fluoro-uracil in surgical treatment of primary open angle glaucoma: a prospective study.
Topics: Aged; Daunorubicin; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Injection | 1992 |
A randomized study of trabeculectomy and subconjunctival administration of fluorouracil in primary glaucomas.
Topics: Aged; Aged, 80 and over; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans; Injections; Intraocula | 1992 |
Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery.
Topics: Adult; Aged; Aged, 80 and over; Corneal Diseases; Epithelium; Female; Fluorouracil; Glaucoma; Humans | 1992 |
Risk factors for suprachoroidal hemorrhage after filtering surgery. The Fluorouracil Filtering Surgery Study Group.
Topics: Aged; Cataract Extraction; Choroid Hemorrhage; Fluorouracil; Glaucoma; Humans; Incidence; Intraocula | 1992 |
Encapsulated filtering bleb and subconjunctival 5-fluorouracil.
Topics: Aged; Aged, 80 and over; Fibroblasts; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; | 1992 |
Trabeculectomy with mitomycin. A comparative study with fluorouracil.
Topics: Adult; Aged; Cicatrix; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; Humans; Intraocula | 1991 |
Use of trabeculectomy with postoperative 5-fluorouracil in patients requiring extremely low intraocular pressure levels to limit further glaucoma progression.
Topics: Aged; Aged, 80 and over; Chronic Disease; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-An | 1991 |
The use of 5-fluorouracil in patients following combined trabeculectomy and cataract extraction.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Combined Modality Therapy; Female; Fluorouracil; Glauc | 1991 |
Fluorouracil Filtering Surgery Study one-year follow-up. The Fluorouracil Filtering Surgery Study Group.
Topics: Adult; Aged; Bias; Chi-Square Distribution; Data Interpretation, Statistical; Female; Fluorouracil; | 1989 |
Fluorouracil Filtering Surgery Study one-year follow-up. The Fluorouracil Filtering Surgery Study Group.
Topics: Adult; Aged; Bias; Chi-Square Distribution; Data Interpretation, Statistical; Female; Fluorouracil; | 1989 |
Fluorouracil Filtering Surgery Study one-year follow-up. The Fluorouracil Filtering Surgery Study Group.
Topics: Adult; Aged; Bias; Chi-Square Distribution; Data Interpretation, Statistical; Female; Fluorouracil; | 1989 |
Fluorouracil Filtering Surgery Study one-year follow-up. The Fluorouracil Filtering Surgery Study Group.
Topics: Adult; Aged; Bias; Chi-Square Distribution; Data Interpretation, Statistical; Female; Fluorouracil; | 1989 |
Effect of postoperative subconjunctival 5-fluorouracil injections on the surgical outcome of trabeculectomy in the Japanese.
Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Conjunctiva; Fluorouracil; Follow-Up Studi | 1989 |
A prospective, randomized study of 5-fluorouracil and filtration surgery.
Topics: Adolescent; Adult; Aged; Child; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; | 1987 |
A randomized study of 5-fluorouracil and filtration surgery.
Topics: Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Postoperative Compl | 1987 |
219 other studies available for fluorouracil and Intraocular Pressure
| Article | Year |
|---|---|
The Norwich trabeculectomy study: risk factor analysis for the development of adverse, thin cystic blebs.
Topics: Antimetabolites; Conjunctiva; Factor Analysis, Statistical; Fluorouracil; Glaucoma; Humans; Intraocu | 2022 |
Subconjunctival Lymphatics Respond to VEGFC and Anti-Metabolites in Rabbit and Mouse Eyes.
Topics: Animals; Antimetabolites; Conjunctiva; Dextrans; Fluorouracil; Glaucoma; Intraocular Pressure; Mice; | 2022 |
Efficacy of postoperative management with 5-fluorouracil injections after XEN Gel Stent implantation.
Topics: Aged; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucoma Drainage Implants; Glaucoma, Op | 2020 |
Visual field progression 8 years after trabeculectomy in Asian eyes: results from The Singapore 5-Fluorouracil Study.
Topics: Adult; Aged; Disease Progression; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Hum | 2020 |
Does bleb needling augmented by mitomycin C or 5-fluorouracil share similar efficacy with no antimetabolites?
Topics: Antimetabolites; Fluorouracil; Humans; Intraocular Pressure; Mitomycin; Nucleic Acid Synthesis Inhib | 2021 |
Results of fluorouracil-augmented Xen45 implantation in primary open-angle and pseudoexfoliation glaucoma.
Topics: Aged; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Glaucoma, Open-Angle; Humans; Intraocular | 2021 |
Efficacy and safety of 5-fluorouracil in infrared monitor guided bleb revision.
Topics: Fluorouracil; Follow-Up Studies; Humans; Intraocular Pressure; Postoperative Complications; Reoperat | 2021 |
Preparation of 5-fluorouracil loaded chitosan microtube via in situ precipitation for glaucoma drainage device application: in vitro and in vivo investigation.
Topics: Chitosan; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Humans; Intraocular Pressure | 2021 |
Use of subconjunctival injections of 5-fluorouracil to rescue and prolong intraocular pressure reduction for a failing Ahmed glaucoma implant.
Topics: Aged; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Glaucoma Drainage Implants; Hu | 2017 |
Three-Year Follow-Up of Trabeculectomy with 5-Fluorouracil.
Topics: Adult; Aged; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Germany; Glaucoma; Humans; Immuno | 2017 |
Comparison of the Outcomes of Trabeculectomy with 5-Fluorouracil versus Ologen Implant in Primary Open-Angle Glaucoma.
Topics: Collagen; Drug Implants; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Glycosaminog | 2017 |
Practice Preferences for Glaucoma Surgery: A Survey of the American Glaucoma Society.
Topics: Alkylating Agents; Cataract; Female; Filtering Surgery; Fluorouracil; Glaucoma Drainage Implants; Gl | 2017 |
Subconjunctival injections of 5-fluorouracil for failing Ahmed glaucoma implants.
Topics: Conjunctiva; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Humans; Injections; Intraocular Pre | 2017 |
Use of subconjunctival injections of 5-fluorouracil to rescue and prolong intraocular pressure reduction for a failing Ahmed glaucoma implant.
Topics: Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Humans; Injections; Intraocular Pressure; Ocular | 2017 |
Retrospective observation on trabeculectomy of primary congenital glaucoma by applying biological amniotic membranes soaked with 5-fluorouracil.
Topics: Adolescent; Amnion; Antimetabolites, Antineoplastic; Biological Dressings; Child; Child, Preschool; | 2018 |
Bilateral Scheie's procedure with Ophthalmic Viscoelastic Device and 5-Fluorouracil.
Topics: Female; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Humans; Immunosuppressive Agents; Inject | 2019 |
Initial trabeculectomy with 5-fluorouracil with or without subconjunctival bevacizumab in the management of pseudoexfoliation glaucoma.
Topics: Aged; Angiogenesis Inhibitors; Antihypertensive Agents; Bevacizumab; Exfoliation Syndrome; Female; F | 2019 |
Needling With 5-Fluorouracil (5-FU) After XEN Gel Stent Implantation: 6-Month Outcomes.
Topics: Aged; Aged, 80 and over; Exfoliation Syndrome; Female; Fluorouracil; Gels; Glaucoma; Glaucoma Draina | 2018 |
Needle revision outcomes after glaucoma filtering surgery: survival analysis and predictive factors.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Combined Modality Therapy; Female; Fluorouracil; Gl | 2020 |
Effect of 2 Novel Sustained-release Drug Release Systems on Bleb Fibrosis: An In Vivo Trabeculectomy Study in a Rabbit Model.
Topics: Absorbable Implants; Animals; Drug Delivery Systems; Drug Implants; Drug Liberation; Endophthalmitis | 2019 |
Comparison of Efficacy and Safety of Bleb Needle Revision With and Without 5-Fluorouracil for Failing Trabeculectomy Bleb.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans | 2019 |
Outcomes of Combined Ahmed Glaucoma Valve and Trabeculectomy Revision With Adjunctive Antimetabolite.
Topics: Aged; Aged, 80 and over; Antimetabolites; Case-Control Studies; Chemotherapy, Adjuvant; Combined Mod | 2019 |
5-Fluorouracil augmented needle revision of trabeculectomy: does the location of outflow resistance make a difference?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Child; Conjunctiva; Fem | 2013 |
Impact of application of bio-amniotic membrane immersed in 5-fluorouracil solution in trabeculectomy on rabbit retina.
Topics: Amnion; Animals; Chromatography, High Pressure Liquid; Female; Fluorouracil; Glaucoma; Immunosuppres | 2013 |
[Long-term results after trabeculectomy with 5-fluorouracil].
Topics: Aged; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; Humans; Immunosuppressive Agents; I | 2014 |
Nd:YAG laser goniopuncture for late bleb failure after trabeculectomy with adjunctive mitomycin C.
Topics: Aged; Alkylating Agents; Female; Fluorouracil; Glaucoma; Gonioscopy; Humans; Intraocular Pressure; L | 2014 |
Iridocorneal endothelial syndrome.
Topics: Adult; Fluorouracil; Glaucoma; Glaucoma, Angle-Closure; Gonioscopy; Humans; Intraocular Pressure; Ir | 2014 |
Ex-PRESS outcomes using mitomycin-C, Ologen alone, Ologen with 5-fluorouracil.
Topics: Aged; Alkylating Agents; Anthracenes; Antihypertensive Agents; Collagen; Combined Modality Therapy; | 2015 |
Outcomes: Trabeculectomy Bleb Needle Revision With 5-Fluorouracil.
Topics: Aged; Antihypertensive Agents; Antimetabolites; Combined Modality Therapy; Female; Fluorouracil; Fol | 2016 |
Application of 5-Fluorouracil-Polycaprolactone Sustained-Release Film in Ahmed Glaucoma Valve Implantation Inhibits Postoperative Bleb Scarring in Rabbit Eyes.
Topics: Animals; Anterior Eye Segment; Cicatrix; Delayed-Action Preparations; Fluorouracil; Glaucoma; Glauco | 2015 |
Needle Revision With 5-fluorouracil for the Treatment of Ahmed Glaucoma Valve Filtering Blebs: 5-Fluoruracil Needling Revision can be a Useful and Safe Tool in the Management of Failing Ahmed Glaucoma Valve Filtering Blebs.
Topics: Aged; Antimetabolites; Combined Modality Therapy; Female; Filtering Surgery; Fluorouracil; Follow-Up | 2016 |
Transconjunctival Revision With Mitomycin-C Following Failed Trabeculectomy.
Topics: Aged; Aged, 80 and over; Alkylating Agents; Combined Modality Therapy; Conjunctiva; Female; Fluorour | 2016 |
Effect of mitomycin c and 5-flurouracil adjuvant therapy on the outcomes of Ahmed glaucoma valve implantation.
Topics: Administration, Topical; Aged; Antibiotics, Antineoplastic; Dose-Response Relationship, Drug; Drug T | 2017 |
Results From a Modified Bleb Needling Procedure With Continuous Infusion Performed in the Operating Room.
Topics: Aged; Conjunctiva; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Injections; Intraocular Press | 2016 |
Aqueous shunts in glaucoma: a report by the American Academy of Ophthalmology.
Topics: Academies and Institutes; Alkylating Agents; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; | 2008 |
Ahmed valve implantation with adjunctive mitomycin C and 5-fluorouracil: long-term outcomes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alkylating Agents; Cataract Extraction; Combined Modalit | 2008 |
Controlled delivery of 5-chlorouracil using poly(ortho esters) in filtering surgery for glaucoma.
Topics: Animals; Antimitotic Agents; Apoptosis; Blister; Cell Death; Cell Proliferation; Cell Survival; Cell | 2008 |
Trabeculectomy with an active postoperative regimen: results and resource utilization.
Topics: Aged; Conjunctiva; Female; Fluorouracil; Glaucoma; Glaucoma, Open-Angle; Humans; Injections; Intraoc | 2009 |
Subconjunctival sustained release 5-fluorouracil for glaucoma filtration surgery.
Topics: Animals; Antimetabolites; Aqueous Humor; Chromatography, High Pressure Liquid; Conjunctiva; Delayed- | 2008 |
Comparison of 90-s versus 5-min intraoperative 5-fluorouracil in trabeculectomy.
Topics: Aged; Antihypertensive Agents; Antimetabolites; Blister; Cicatrix; Female; Fluorouracil; Follow-Up S | 2010 |
Postoperative use of bevacizumab as an antifibrotic agent in glaucoma filtration surgery in the rabbit.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimet | 2009 |
Restricted post-trabeculectomy bleb formation by conjunctival scarring.
Topics: Antimetabolites; Blister; Cicatrix; Combined Modality Therapy; Conjunctiva; Conjunctival Diseases; C | 2009 |
Long-term outcomes of needle revision of trabeculectomy blebs with mitomycin C and 5-fluorouracil: a comparative safety and efficacy report.
Topics: Aged; Alkylating Agents; Antihypertensive Agents; Combined Modality Therapy; Female; Fluorouracil; F | 2009 |
Bilateral ocular hypertension with rapidly progressive optic neuropathy in a teen.
Topics: Adolescent; Antimetabolites; Disease Progression; Female; Fluorouracil; Fundus Oculi; Glaucoma, Open | 2009 |
The prognostic value of the wuerzburg bleb classification score for the outcome of trabeculectomy.
Topics: Antimetabolites; Blister; Combined Modality Therapy; Conjunctiva; Female; Fluorouracil; Follow-Up St | 2011 |
Combined trabeculotomy-trabeculectomy augmented with 5-fluorouracil in paediatric glaucoma.
Topics: Alkylating Agents; Child; Child, Preschool; Combined Modality Therapy; Female; Fluorouracil; Humans; | 2011 |
Ophthalmic drug-loaded N,O-carboxymethyl chitosan hydrogels: synthesis, in vitro and in vivo evaluation.
Topics: Administration, Topical; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevaciz | 2010 |
[Corneal epitheliopathy following trabeculectomy with postoperative adjunctive 5-fluorouracil].
Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Combined Modality Therapy; Corne | 2010 |
Postoperative complications after glaucoma surgery for primary angle-closure glaucoma vs primary open-angle glaucoma.
Topics: Aged; Female; Fluorouracil; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Gonioscopy; Humans; Incid | 2011 |
Paediatric glaucoma: baby-steps to improved control.
Topics: Adolescent; Antimetabolites; Child; Child, Preschool; Combined Modality Therapy; Fluorouracil; Human | 2011 |
Bleb needling with subconjunctival injection of sodium hyaluronate 1.4%: 1-year outcomes.
Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Conjunctiva; Drug Therapy, Combination; Female; F | 2011 |
Snailtrack corneal changes following subconjunctival injection of 5-fluorouracil.
Topics: Antimetabolites; Conjunctiva; Corneal Diseases; Endothelium, Corneal; Fluorouracil; Glaucoma; Humans | 2012 |
Enhanced trabeculectomy in a UK district general hospital setting: is selective use of 5-fluorouracil all that is required?
Topics: Aged; Aged, 80 and over; Antimetabolites; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Hospita | 2013 |
Trabeculectomy with antiproliferative agents in uveitic glaucoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineopla | 2002 |
Long-term follow-up of initially successful trabeculectomy with 5-fluorouracil injections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Child; Child, Preschool; Conjunctiva; F | 2002 |
The role of needle revision and 5-fluorouracil application over the filtration site in the management of bleb failure after trabeculectomy: a prospective study.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Female; Fluorou | 2003 |
[Assessment of nonpenetrating deep sclerectomy with reticulated hyaluronic acid implant SKGEL and/or preoperative application of 5-luorouracil: results of 2 and a half years].
Topics: Adult; Aged; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Hyaluronic Acid; | 2003 |
Postoperative 5-fluorouracil versus intraoperative mitomycin C in high-risk glaucoma filtering surgery: extended follow up.
Topics: Adult; Aged; Female; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Intrao | 2003 |
Optical coherence tomography assessment of retinal nerve fiber layer thickness changes after glaucoma surgery.
Topics: Chemotherapy, Adjuvant; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Interferometry; Intraocu | 2003 |
Intraoperative 5-fluorouracil application during primary trabeculectomy in Nigeria: a comparative study.
Topics: Aged; Antimetabolites; Developing Countries; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Huma | 2003 |
Needling revision of failed filtering blebs after trabeculectomy: a retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Child, Preschool; Conjunctiva; Female; Fluorouracil; Follow-Up Studi | 2003 |
Intensified postoperative care versus conventional follow-up: a retrospective long-term analysis of 177 trabeculectomies.
Topics: Aged; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle | 2004 |
Outcome of consecutive trabeculectomy.
Topics: Adolescent; Adult; Aged; Antimetabolites; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Intrao | 2004 |
Needle revision of failing and failed trabeculectomy blebs with adjunctive 5-fluorouracil: survival analysis.
Topics: Adult; Aged; Aged, 80 and over; Blister; Chemotherapy, Adjuvant; Conjunctiva; Female; Fibrosis; Fluo | 2004 |
Effect of temporal corneal phacoemulsification on intraocular pressure in eyes with prior trabeculectomy with an antimetabolite.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Case-Control Studies; Cornea; Female; Fluorouracil; | 2004 |
Viscocanalostomy versus trabeculectomy.
Topics: Anterior Eye Segment; Antimetabolites, Antineoplastic; Conjunctiva; Fluorouracil; Glaucoma, Open-Ang | 2004 |
Operative revision of non-functioning filtering blebs with 5-fluorouracil to regain intraocular pressure control.
Topics: Adult; Aged; Antimetabolites; Conjunctiva; Female; Filtering Surgery; Fluorouracil; Glaucoma, Open-A | 2004 |
Needle revision of failed filtering blebs using 5-Fluorouracil and a combined ab-externo and ab-interno approach.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Combined Modality Therapy; Conjunctiva; Fe | 2005 |
Augmented trabeculectomy in paediatric glaucoma.
Topics: Antimetabolites; Child; Child, Preschool; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; | 2005 |
Use of surodex in phacotrabeculectomy surgery.
Topics: Anterior Eye Segment; Dexamethasone; Drug Delivery Systems; Fluorouracil; Follow-Up Studies; Glaucom | 2005 |
Ahmed valve drainage implant surgery in the management of paediatric aphakic glaucoma.
Topics: Adolescent; Antihypertensive Agents; Aphakia, Postcataract; Child; Child, Preschool; Female; Fluorou | 2005 |
Do injections of 5-fluorouracil after trabeculectomy have toxic effects on the anterior segment?
Topics: Animals; Anterior Eye Segment; Antimetabolites; Aqueous Humor; Female; Fluorouracil; Injections, Int | 2005 |
Loss of vision after phacotrabeculectomy.
Topics: Antimetabolites; Blindness; Chemotherapy, Adjuvant; Conjunctival Diseases; Cysts; Diabetes Complicat | 2005 |
Short term experience with "modern" trabeculectomy augmented with intraoperative antimetabolites.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Fluorouracil; Follow-Up Studies; Glauco | 2005 |
Filtering blebs imaging by optical coherence tomography.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Blister; Child; Combined Modality Thera | 2005 |
Audit of trabeculectomy at a tertiary referral hospital in East Africa.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Antimetabolites; Female; Fluorouracil; Glau | 2005 |
Is intraocular pressure in the early postoperative period predictive of antimetabolite-augmented filtration surgery success?
Topics: Aged; Antimetabolites; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; Humans; Intraocula | 2005 |
Failed trabeculectomy.
Topics: Antimetabolites; Conjunctiva; Fistula; Fluorouracil; Glaucoma Drainage Implants; Glaucoma, Open-Angl | 2005 |
[Visual acuty after trabeculectomy].
Topics: Antimetabolites; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Tr | 2005 |
[Clinical observation of needle revision and 5-fluorouracil subconjunctival injection on the dysfunctional filtering blebs].
Topics: Adult; Aged; Combined Modality Therapy; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glauco | 2005 |
Mitomycin C augmented glaucoma surgery: evolution of filtering bleb avascularity, transconjunctival oozing, and leaks.
Topics: Aged; Blister; Conjunctiva; Conjunctival Diseases; Female; Fluorouracil; Glaucoma; Humans; Intraocul | 2006 |
Phacoemulsification in patients with previous trabeculectomy: role of 5-fluorouracil.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Antimetabolites; Drug Administration Schedule; Dru | 2007 |
Review of consecutive phacotrabeculectomies supplemented with early needle revision and antimetabolites.
Topics: Aged; Aged, 80 and over; Antimetabolites; Cataract; Female; Fluorouracil; Glaucoma; Humans; Intraocu | 2006 |
[Needle revision of late failing filtering blebs after glaucoma surgery].
Topics: Aged; Aged, 80 and over; Female; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Immunosuppressiv | 2006 |
Dose, timing and frequency of subconjunctival 5-fluorouracil injections after glaucoma filtering surgery.
Topics: Adult; Aged; Aged, 80 and over; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans; Immunosuppressi | 2007 |
Immediate postoperative intraocular pressure measurements after trabeculectomy with releasable sutures.
Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; False Negative Reactions; Female; Fluorou | 2006 |
Intraocular pressure outcome in primary 5FU phacotrabeculectomies compared with 5FU trabeculectomies.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cataract; Combined Modality Therapy | 2006 |
Frequency of bleb manipulations after trabeculectomy surgery.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Blister; Female; Fluorouracil; Follow-Up Studies; H | 2007 |
Phacotrabeculectomy study.
Topics: Alkylating Agents; Antihypertensive Agents; Cataract; Fluorouracil; Glaucoma; Humans; Intraocular Pr | 2007 |
[Late needling with 5-fluorouracil when scarring of filtering bleb seems imminent].
Topics: Blister; Cicatrix; Cicatrix, Hypertrophic; Drug Administration Schedule; Filtering Surgery; Fluorour | 2007 |
Post-operative complication of trabeculectomy in Ibadan, Nigeria: outcome of 1-year follow-up.
Topics: Adult; Aged; Anterior Chamber; Antimetabolites; Blister; Epidemiologic Methods; Female; Fluorouracil | 2009 |
Needling revision of trabeculectomies bleb morphology and long-term survival.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans | 2008 |
5-fluorouracil and glaucoma filtering surgery. II. A pilot study.
Topics: Adolescent; Adult; Aged; Cataract Extraction; Child; Cicatrix; Combined Modality Therapy; Dose-Respo | 1984 |
5-fluorouracil and glaucoma filtering surgery: I. An animal model.
Topics: Animals; Aotus trivirgatus; Cicatrix; Combined Modality Therapy; Fibroblasts; Fluorouracil; Glaucoma | 1984 |
Intraocular pressure control following microtrabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Intraocular Pres | 1995 |
[Experiences with sclerostomy with the Holmium laser].
Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Glaucom | 1994 |
Removable sutures in glaucoma surgery.
Topics: Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Mitomycin; Suture Techniques; Time Factors; Tr | 1994 |
One-year follow-up results of combined mitomycin C trabeculectomy and extracapsular cataract extraction.
Topics: Adult; Aged; Astigmatism; Cataract; Cataract Extraction; Female; Fluorouracil; Follow-Up Studies; Gl | 1995 |
Profound long-term hypotony without maculopathy after trabeculectomy with antimetabolite.
Topics: Aged; Female; Fluorescein Angiography; Fluorouracil; Fundus Oculi; Glaucoma, Open-Angle; Humans; Int | 1994 |
Incidence of complications following 5-fluorouracil with trabeculectomies.
Topics: Combined Modality Therapy; Corneal Diseases; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Inci | 1993 |
[Hydrodynamics of the rabbit eye after general administration of cytostatics].
Topics: Animals; Biological Transport, Active; Ciliary Body; Fluorouracil; Intraocular Pressure; Methotrexat | 1994 |
Single intraoperative applications of 5-fluorouracil during filtration surgery: early results.
Topics: Adolescent; Adult; Aged; Child, Preschool; Female; Filtration; Fluorouracil; Glaucoma; Humans; Intra | 1994 |
[5-fluorouracil injection treatment after fistulating glaucoma operations].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Combined Modality Therapy; Female; Fluorouracil; | 1993 |
[5-fluorouracil in goniotrepanation with poor prognosis. Results of 1-year follow-up].
Topics: Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; I | 1993 |
Intra-operative use of 5-fluorouracil in glaucoma filtering surgery.
Topics: Adult; Aged; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Infant; I | 1993 |
Intraoperative 5-fluorouracil for filtration surgery in the rabbit.
Topics: Animals; Conjunctiva; Double-Blind Method; Fluorouracil; Glaucoma; Injections; Intraocular Pressure; | 1993 |
Trabeculectomy with 5-fluorouracil vs single-plate Molteno implantation.
Topics: Adult; Aged; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure | 1993 |
5-FU-supplemented phacoemulsification, posterior chamber intraocular lens implantation, and trabeculectomy.
Topics: Aged; Cataract Extraction; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; | 1993 |
The role of 5-fluorouracil in complicated glaucomas.
Topics: Adult; Aphakia; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Glaucoma, Neovascular; Humans; In | 1993 |
Filtering surgery with 5-fluorouracil subsequent to Molteno implant.
Topics: Adolescent; Adult; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Injections; Intraocula | 1993 |
Needling revision of failed filtering blebs with adjunctive 5-fluorouracil.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Female; Fluorouracil; Follow-Up Studies; Glaucoma, | 1993 |
Holmium laser sclerectomy. Success and complications.
Topics: Aged; Choroid Hemorrhage; Chronic Disease; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intrao | 1993 |
Sturge-Weber syndrome: management of glaucoma with combined trabeculotomy-trabeculectomy.
Topics: Child; Child, Preschool; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Infant; Infant, | 1993 |
[Combined posterior chamber intraocular lens implantation and trabeculectomy--a life-table analysis of postoperative clinical course].
Topics: Aged; Female; Fluorouracil; Humans; Intraocular Pressure; Lenses, Intraocular; Life Tables; Male; Pr | 1993 |
Anterior chamber reaction after mitomycin and 5-fluorouracil trabeculectomy: a comparative study.
Topics: Anterior Chamber; Aqueous Humor; Biological Transport, Active; Blood; Chemotherapy, Adjuvant; Eye Pr | 1993 |
Subconjunctival THC:YAG ("holmium") laser thermal sclerostomy ab externo. A one-year report.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Cohort Studies; Conjunctiva; Female; Fluorouracil | 1993 |
Effects of intraoperative 5-fluorouracil or mitomycin C on glaucoma filtration surgery in the rabbit.
Topics: Animals; Double-Blind Method; Drug Evaluation, Preclinical; Fluorouracil; Glaucoma; Intraocular Pres | 1993 |
Late complications after glaucoma filtering surgery with adjunctive 5-fluorouracil.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Child; Child, Preschool; Eye Dis | 1993 |
Hypotonous maculopathy after trabeculectomy with subconjunctival 5-fluorouracil.
Topics: Adult; Fluorouracil; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Macula Lutea; Male; Ocular | 1993 |
Pump shunt success underscored.
Topics: Fluorouracil; Glaucoma, Neovascular; Humans; Intraocular Pressure; Prostheses and Implants; Treatmen | 1993 |
Surgical management of post-traumatic angle recession glaucoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Chamber; Child; Combined Modality Therapy; Drai | 1993 |
Treatment of failing glaucoma filtering cystic blebs with tissue plasminogen activator (tPA).
Topics: Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Drug Therapy, Combination; Female; Filtering Surger | 1995 |
Trabeculectomy at the inferior limbus.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Eye Segment; Chemotherapy, Adjuvant; Child; Chi | 1996 |
Use of oversized bandage soft contact lenses in the management of early hypotony following filtration surgery.
Topics: Aged; Aged, 80 and over; Antimetabolites; Contact Lenses, Hydrophilic; Female; Fluorouracil; Follow- | 1996 |
Sustained-release subconjunctival 5-fluorouracil.
Topics: Aged; Antimetabolites; Conjunctiva; Delayed-Action Preparations; Drug Implants; Female; Fluorouracil | 1996 |
Late bleb leakage after trabeculectomy with 5-fluorouracil or mitomycin C.
Topics: Adult; Aged; Chemotherapy, Adjuvant; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Intraocular | 1996 |
Low-dose perioperative 5-fluorouracil in trabeculectomy.
Topics: Antimetabolites; Drug Administration Routes; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Huma | 1996 |
Ultrasonographic findings of the optic disc in congenital glaucoma.
Topics: Antimetabolites; Corneal Opacity; Cryotherapy; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Hu | 1996 |
[Single dose intraoperative administration of 5-fluorouracil (5-FU) in trabeculectomy. Long-term results of a pilot study].
Topics: Aged; Antimetabolites; Cell Division; Exfoliation Syndrome; Female; Fluorouracil; Glaucoma, Open-Ang | 1996 |
[Antiproliferative therapy with 5-fluorouracil in erbium:YAG laser sclerostomy ab externo].
Topics: Antimetabolites; Cell Division; Cicatrix; Combined Modality Therapy; Female; Fluorouracil; Glaucoma; | 1996 |
Temporal corneal phacoemulsification combined with superior trabeculectomy. A retrospective case-control study.
Topics: Aged; Aged, 80 and over; Antimetabolites; Case-Control Studies; Cornea; Female; Fluorouracil; Glauco | 1997 |
Pseudotumor cerebri appearing with unilateral papilledema after trabeculectomy.
Topics: Acetazolamide; Adult; Antimetabolites; Carbonic Anhydrase Inhibitors; Female; Fluorouracil; Fundus O | 1997 |
Results of intraoperative 5-fluorouracil or lower dose mitomycin-C administration on initial trabeculectomy surgery.
Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites; Chemotherapy, Adjuvant | 1997 |
Needling revision of glaucoma drainage device filtering blebs.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Chemotherapy, Adjuvant; Drainage; Female; Fluoroura | 1997 |
Risk factors for unsatisfactory intraocular pressure control in combined trabeculectomy and cataract surgery.
Topics: Aged; Aged, 80 and over; Antimetabolites; Cataract; Cataract Extraction; Female; Fluorouracil; Follo | 1997 |
[Surgical revision of failed filtering bleb with mitomycin C].
Topics: Adult; Aged; Aged, 80 and over; Female; Filtering Surgery; Fluorouracil; Follow-Up Studies; Glaucoma | 1997 |
Small incision trabeculectomy avoiding Tenon's capsule. A new procedure for glaucoma surgery.
Topics: Adult; Aged; Aged, 80 and over; Conjunctiva; Connective Tissue; Fluorouracil; Follow-Up Studies; Gla | 1997 |
5-Fluorouracil in primary combined glaucoma surgery.
Topics: Antimetabolites; Cornea; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Lenses, Intraocular; | 1997 |
Temporal corneal phacoemulsification in filtered glaucoma patients.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cornea; Female; Fluorouracil; Follow-Up Studies; Glau | 1997 |
Long-term results and complications after trabeculectomy with a single per-operative application of 5-fluorouracil.
Topics: Adult; Aged; Antimetabolites; Eye Diseases; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Human | 1997 |
Management of coexisting pseudophakic bullous keratopathy and open-angle glaucoma.
Topics: Administration, Topical; Aged; Cataract Extraction; Corneal Diseases; Female; Fluorouracil; Follow-U | 1998 |
Modification of trabeculectomy with single-dose intraoperative 5-Fluorouracil application.
Topics: Antimetabolites; Chemotherapy, Adjuvant; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; | 1998 |
Late removal of releasable sutures after trabeculectomy or combined trabeculectomy with cataract extraction supplemented with antifibrotics.
Topics: Aged; Cataract Extraction; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pr | 1998 |
Antimetabolites in glaucoma surgery: our experiences and results.
Topics: Antimetabolites; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Intraopera | 1997 |
The treatment of encapsulated trabeculectomy blebs in an out-patient setting using a needling technique and subconjunctival 5-fluorouracil injection.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Combined Modality Therapy; Cysts; Eye Diseases; Fem | 1998 |
[Peroperative administration of 5-fluorouracil during trabeculectomy in complicated glaucoma in children].
Topics: Adolescent; Antimetabolites; Child; Child, Preschool; Female; Fluorouracil; Glaucoma; Humans; Intrao | 1998 |
Management of large, leaking, and inadvertent filtering blebs with the neodymium:YAG laser.
Topics: Aged; Aqueous Humor; Female; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Intraocular Pressure | 1998 |
Needling revision of glaucoma drainage device filtering blebs.
Topics: Chemotherapy, Adjuvant; Drainage; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Intraocular Pre | 1998 |
Trabeculectomy with intraoperative 5-fluorouracil.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Fluorouracil; Glaucoma; Humans; Int | 1998 |
Trabeculectomy survival with and without intra-operative 5-fluorouracil application in an Asian population.
Topics: Administration, Topical; Antimetabolites; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; | 1998 |
Occlusive ligature and standardized fenestration of a Baerveldt tube with and without antimetabolites for early postoperative intraocular pressure control.
Topics: Aged; Antimetabolites; Aqueous Humor; Female; Fluorouracil; Glaucoma; Glaucoma Drainage Implants; Hu | 1998 |
Comparison of deep sclerectomy with collagen implant and trabeculectomy in open-angle glaucoma.
Topics: Aged; Collagen; Female; Fluorouracil; Follow-Up Studies; Glaucoma Drainage Implants; Glaucoma, Open- | 1999 |
Malignant glaucoma.
Topics: Anterior Chamber; Chronic Disease; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Angle-Closure; | 1999 |
Mitomycin C-augumented trabeculectomy with postoperative wound modulation in pediatric glaucoma.
Topics: Adolescent; Chemotherapy, Adjuvant; Child; Child, Preschool; Female; Fluorouracil; Follow-Up Studies | 1999 |
Comparison of phacotrabeculectomy with 5-fluorouracil, mitomycin-C, and without antifibrotic agents.
Topics: Aged; Cataract; Chemotherapy, Adjuvant; Fibrosis; Fluorouracil; Glaucoma; Humans; Intraocular Pressu | 1999 |
[Use of "low dose" 5-fluorouracil during trabeculectomy].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Female; Fluorouracil; Follow-Up Studies; Glaucoma; | 1999 |
Combined versus sequential phacotrabeculectomy with intraoperative 5-fluorouracil.
Topics: Aged; Antimetabolites; Cataract; Conjunctiva; Fluorouracil; Glaucoma, Open-Angle; Humans; Injections | 2000 |
Amniotic membrane transplantation or conjunctival limbal autograft for limbal stem cell deficiency induced by 5-fluorouracil in glaucoma surgeries.
Topics: Aged; Amnion; Cell Transplantation; Conjunctiva; Corneal Diseases; Epithelial Cells; Epithelium, Cor | 2000 |
Glaucoma surgery with or without adjunctive antiproliferatives in normal tension glaucoma: 1 intraocular pressure control and complications.
Topics: Aged; Antimetabolites; Chemotherapy, Adjuvant; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; I | 2000 |
Long-term follow-up of trabeculectomy with intraoperative 5-fluorouracil for uveitis-related glaucoma.
Topics: Adolescent; Adult; Aged; Antimetabolites; Child; Female; Fluorouracil; Follow-Up Studies; Glaucoma; | 2000 |
After-cataract and secondary glaucoma in the aphakic infant rabbit.
Topics: Animals; Animals, Newborn; Anterior Chamber; Aphakia, Postcataract; Cataract; Fluorouracil; Glaucoma | 2000 |
Outcomes of combined cataract extraction, lens implantation, and trabeculectomy surgeries.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Cataract; Cataract Extraction; Female; | 2000 |
Wound modulation after trabeculectomy by different formulations of antimetabolites in rabbits.
Topics: Animals; Antimetabolites; Biocompatible Materials; Conjunctiva; Dose-Response Relationship, Drug; Dr | 2000 |
Success criteria and success rates in trabeculectomy with and without intraoperative antimetabolites using intensified postoperative care (IPC).
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Female; Fluorouracil; Glaucoma; Humans; Intraocular | 2000 |
A new poly(ortho ester)-based drug delivery system as an adjunct treatment in filtering surgery.
Topics: Animals; Anterior Eye Segment; Aqueous Humor; Biocompatible Materials; Chemotherapy, Adjuvant; Drug | 2001 |
[Use of 5-fluorouracil in trabeculectomy].
Topics: Adult; Aged; Aged, 80 and over; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; | 2000 |
Should antiproliferatives be used in filtering surgery of normal tension glaucoma?
Topics: Antineoplastic Agents; Filtering Surgery; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Mito | 2001 |
Glaucoma surgery with or without adjunctive antiproliferatives in normal tension glaucoma: 2 Visual field progression.
Topics: Aged; Antimetabolites; Chemotherapy, Adjuvant; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; I | 2001 |
Long-term surgical outcomes of patients with glaucoma secondary to the iridocorneal endothelial syndrome.
Topics: Adult; Antihypertensive Agents; Corneal Diseases; Endothelium, Corneal; Fluorouracil; Follow-Up Stud | 2001 |
Slow release of the antimetabolite 5-fluorouracil (5-FU) from modified Baerveldt glaucoma drains to prolong drain function.
Topics: Animals; Antimetabolites; Biocompatible Materials; Collagen; Delayed-Action Preparations; Drug Impla | 2001 |
The efficacy and safety of intraoperative and/or postoperative 5-fluorouracil in trabeculectomy and phacotrabeculectomy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antimetabolites; Cataract; Female; Fluorouracil; Glaucom | 2001 |
Risk factors for failure of 5-fluorouracil needling revision for failed conjunctival filtration blebs.
Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cataract Extraction; Conjunctiva; Female; | 2001 |
Long-term follow-up of initial 5-fluorouracil trabeculectomy in primary open-angle glaucoma in Japanese patients.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Conjunctiva; Female; Fluorouracil; Follow-Up Studie | 2001 |
[Influence on tear film of postoperative 5-fluourouracil and intraoperative mitomycin C in glaucoma filtration surgery].
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Conjunctiva; Dry Eye Synd | 2001 |
Predictors for success of needle revision of failing filtration blebs.
Topics: Aged; Antimetabolites; Conjunctiva; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Ma | 2002 |
Late-onset transconjunctival oozing and point leak of aqueous humor from filtering bleb after trabeculectomy.
Topics: Antimetabolites; Aqueous Humor; Chemotherapy, Adjuvant; Conjunctiva; Cross-Sectional Studies; Female | 2002 |
[Antimetabolites in glaucoma surgery--long-term results].
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites; Fluorouracil; Glaucoma; Humans; Intraocular Pressur | 2002 |
Antimetabolites in the surgical treatment of glaucomas.
Topics: Animals; Aotidae; Cell Division; Fibroblasts; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; | 1992 |
Glaucoma filtering surgery with postoperative 5-fluorouracil in patients with intraocular inflammatory disease.
Topics: Adolescent; Adult; Aged; Cataract Extraction; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; | 1992 |
Outcome of White pump shunt surgery for neovascular glaucoma in Asians.
Topics: Adult; Aged; Cell Count; Drainage; Endothelium, Corneal; Female; Fluorouracil; Glaucoma, Neovascular | 1992 |
Treatment of encapsulated blebs with 30-gauge needling and injection of low-dose 5-fluorouracil.
Topics: Adult; Aged; Conjunctival Diseases; Cysts; Female; Fluorouracil; Glaucoma, Angle-Closure; Glaucoma, | 1992 |
Intraoperative application of 5-fluorouracil during trabeculectomy.
Topics: Adult; Aged; Aged, 80 and over; Cicatrix; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; | 1992 |
Trabeculectomy with 5-fluorouracil subsequent to circular buckling operation and cataract extraction.
Topics: Adult; Aged; Atropine; Cataract Extraction; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open- | 1992 |
Results of intraoperative 5-fluorouracil supplementation on trabeculectomy for open-angle glaucoma.
Topics: Administration, Topical; Adult; Aged; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; | 1992 |
Combined cataract extraction and filtering surgery.
Topics: Cataract Extraction; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Lenses, In | 1992 |
Postoperative subconjunctival 5-fluorouracil injections and success probability of trabeculectomy in Japanese: results of 5-year follow-up.
Topics: Adult; Conjunctiva; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Injections; Intra | 1992 |
Subconjunctival injection of 5-fluorouracil following trabeculectomy for congenital and infantile glaucoma.
Topics: Child; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Injections; Intraocul | 1992 |
Combined no-stitch phacoemulsification cataract extraction with foldable silicone intraocular implant and holmium laser sclerostomy followed by 5-FU injections.
Topics: Aged; Cataract Extraction; Fluorouracil; Glaucoma, Open-Angle; Humans; Injections; Intraocular Press | 1992 |
Design and results of trabeculectomy operation for use with 5-fluorouracil.
Topics: Adult; Aged; Aged, 80 and over; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; | 1992 |
5-fluorouracil in trabeculectomy for patients under the age of 40 years.
Topics: Adolescent; Adult; Age Factors; Child; Female; Fluorouracil; Follow-Up Studies; Glaucoma, Open-Angle | 1992 |
Reversible corneal keratinization following trabeculectomy and treatment with 5-fluorouracil.
Topics: Aged; Conjunctiva; Corneal Diseases; Fluorouracil; Glaucoma, Open-Angle; Humans; Intraocular Pressur | 1990 |
Effects of subconjunctival 5-fluorouracil injections on the corneal endothelium and ciliary epithelium.
Topics: Animals; Aqueous Humor; Ciliary Body; Conjunctiva; Dextrans; Endothelium, Corneal; Epithelium; Femal | 1990 |
5-FU trabeculectomy.
Topics: Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Trabeculectomy | 1992 |
Initial 5-fluorouracil trabeculectomy in young patients.
Topics: Adolescent; Adult; Combined Modality Therapy; Evaluation Studies as Topic; Female; Fluorouracil; Fol | 1992 |
Regulating the dose of 5-fluorouracil to prevent filtering bleb scarring.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Chamber; Child; Cicatrix; Conjunctiva; Dosage F | 1991 |
Trabeculectomy with 5-fluorouracil.
Topics: Aged; Aged, 80 and over; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Glaucoma, Angle | 1991 |
[5-Fu as remedy for unsuccessful glaucoma filtration surgery].
Topics: Adolescent; Adult; Child; Female; Fluorouracil; Glaucoma; Humans; Injections; Intraocular Pressure; | 1991 |
Initial 5-fluorouracil trabeculectomy in uncomplicated glaucoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Evaluation Studies as Topic; Female; Fluorouracil; Follo | 1991 |
Late bleb-related endophthalmitis after trabeculectomy with adjunctive 5-fluorouracil.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Child; Child, Preschool; Endophth | 1991 |
Subconjunctival THC:YAG laser thermal sclerostomy.
Topics: Adult; Aged; Aged, 80 and over; Child; Conjunctiva; Female; Fluorouracil; Follow-Up Studies; Glaucom | 1991 |
Reducing corneal toxicity of 5-fluorouracil in the early postoperative period following glaucoma filtering surgery.
Topics: Aged; Aged, 80 and over; Aphakia; Corneal Diseases; Female; Fluorouracil; Glaucoma, Open-Angle; Huma | 1991 |
Bandage contact lens augmentation of 5-fluorouracil treatment in glaucoma filtration surgery.
Topics: Aged; Cataract Extraction; Contact Lenses; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Intra | 1991 |
Remission of anterior uveitis by subconjunctival fluorouracil.
Topics: Aged; Conjunctiva; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Middle A | 1991 |
5-Fluorouracil after trabeculectomy and the iridocorneal endothelial syndrome.
Topics: Adult; Cataract Extraction; Conjunctiva; Corneal Diseases; Endothelium, Corneal; Fluorouracil; Follo | 1991 |
Restoring the function of the failed bleb.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drainage; Female; Fluorouracil; Glaucoma; Humans; | 1991 |
Internal sclerostomy with argon contact laser--animal experiment using 5-fluorouracil.
Topics: Animals; Anterior Chamber; Conjunctiva; Fluorouracil; Intraocular Pressure; Laser Therapy; Macaca mu | 1990 |
Primate trabeculectomies with 5-fluorouracil collagen implants.
Topics: Animals; Anterior Chamber; Biological Dressings; Double-Blind Method; Drug Implants; Fibroblasts; Fl | 1990 |
Trabeculectomy with 5-fluorouracil for adult inflammatory glaucoma.
Topics: Adult; Aged; Female; Fluorometholone; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Inflammatio | 1990 |
Adjunctive use of delayed and adjustable low-dose 5-fluorouracil in refractory glaucoma.
Topics: Adolescent; Adult; Aged; Conjunctiva; Dose-Response Relationship, Drug; Drug Administration Schedule | 1990 |
Combined cataract implant and filtering surgery with 5-fluorouracil.
Topics: Aged; Cataract Extraction; Contrast Sensitivity; Female; Fluorouracil; Glaucoma, Angle-Closure; Glau | 1990 |
Delivery of antifibroblast agents as adjuncts to filtration surgery--Part II: Delivery of 5-fluorouracil and bleomycin in a collagen implant: pilot study in the rabbit.
Topics: Animals; Bleomycin; Cell Division; Collagen; Drug Implants; Eye; Female; Fibroblasts; Fluorouracil; | 1986 |
Adjusting the dose of 5-fluorouracil after filtration surgery to minimize side effects.
Topics: Adult; Aged; Female; Fluorouracil; Glaucoma; Humans; Inflammation; Intraocular Pressure; Iris; Male; | 1987 |
Low-dose 5-fluorouracil and glaucoma filtration surgery.
Topics: Adolescent; Adult; Aged; Child; Cornea; Epithelial Cells; Fluorouracil; Follow-Up Studies; Glaucoma; | 1989 |
Long-term results of 5-fluorouracil trabeculectomy for primary open-angle glaucoma.
Topics: Adult; Aged; Epinephrine; Female; Fluorouracil; Glaucoma, Open-Angle; Humans; Injections; Intraocula | 1989 |
External limbal sclerostomy with contact Nd:YAG laser versus surgical knife.
Topics: Animals; Anterior Chamber; Cell Division; Conjunctiva; Fluorouracil; Glaucoma; Intraocular Pressure; | 1989 |
Glaucoma filtration surgery in rabbits using bioerodible polymers and 5-fluorouracil.
Topics: Animals; Biodegradation, Environmental; Double-Blind Method; Drug Implants; Fluorouracil; Glaucoma; | 1987 |
[Use of 5-fluorouracil in the surgery of glaucoma].
Topics: Conjunctiva; Female; Fibrosis; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressu | 1987 |
5-Fluorouracil for trabeculectomy in glaucoma.
Topics: Cicatrix; Female; Fluorouracil; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Pos | 1987 |
Q-switched neodymium-YAG laser trabeculopuncture in monkeys.
Topics: Animals; Cicatrix; Fluorouracil; Hyaluronic Acid; Injections; Intraocular Pressure; Laser Therapy; M | 1985 |