Page last updated: 2024-10-27

fluorouracil and Intestinal Polyps

fluorouracil has been researched along with Intestinal Polyps in 12 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Intestinal Polyps: Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base.

Research Excerpts

ExcerptRelevanceReference
"We examined the outcomes of transanal endoscopic microsurgery excisions with entry into the peritoneal cavity and compared them with those that did not to address our hypothesis that entry is safe with no ill infectious or oncological consequences."1.40Transanal endoscopic microsurgery with entrance into the peritoneal cavity: is it safe? ( D'Andrea, AP; Frenkel, JL; Greenleaf, CE; Marks, JH, 2014)
"Only two of them bore colonic cancer."1.28Disappearance of hyperplastic polyposis after resection of rectal cancer. Report of two cases. ( Fujita, S; Kusunoki, M; Sakanoue, Y; Shoji, Y; Utsunomiya, J; Yamamura, T; Yanagi, H, 1991)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19908 (66.67)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Han, Y1
Cai, H1
Ma, L1
Ding, Y1
Tan, X1
Liu, Y1
Su, T1
Yu, Y1
Chang, W1
Zhang, H1
Fu, C1
Cao, G1
Marks, JH1
Frenkel, JL1
Greenleaf, CE1
D'Andrea, AP1
Darsigny, M1
Babeu, JP1
Seidman, EG1
Gendron, FP1
Levy, E1
Carrier, J1
Perreault, N1
Boudreau, F1
Borchard, F1
Shapiro, CM1
Bitran, JD1
Shapiro, RA1
Wallack, MK1
Rosato, FE1
Brown, AS1
Rosato, EF1
Kolleg, MK1
Welch, CE1
Kusunoki, M1
Fujita, S1
Sakanoue, Y1
Shoji, Y1
Yanagi, H1
Yamamura, T1
Utsunomiya, J1
Donaldson, GA1
Welch, JP1
Lapsa, RKh1
Astrakhan, VI1

Reviews

3 reviews available for fluorouracil and Intestinal Polyps

ArticleYear
[The diffuse endocrine system and the carcinoids of the alimentary tract. Part I: Orthological aspects and common morphological features of the carcinoids (author's transl)].
    Zeitschrift fur Gastroenterologie, 1982, Volume: 20, Issue:4

    Topics: Adrenocorticotropic Hormone; Aged; Appendiceal Neoplasms; APUD Cells; Carcinoid Tumor; Carmustine; C

1982
Abdominal surgery (second of three parts).
    The New England journal of medicine, 1975, Oct-30, Volume: 293, Issue:18

    Topics: Abdomen; Acute Disease; Anus Diseases; Appendectomy; Appendicitis; Appendix; Carcinoembryonic Antige

1975
Management of cancer of the colon.
    The Surgical clinics of North America, 1974, Volume: 54, Issue:3

    Topics: Colitis, Ulcerative; Colon; Colonic Diseases; Colonic Neoplasms; Diagnostic Errors; Fluorouracil; Hu

1974

Trials

1 trial available for fluorouracil and Intestinal Polyps

ArticleYear
[Main problems of the method of clinical study of new antineoplastic agents].
    Vestnik Akademii meditsinskikh nauk SSSR, 1966, Volume: 21, Issue:4

    Topics: Antineoplastic Agents; Biopsy; Clinical Trials as Topic; Female; Fluorouracil; Humans; Intestinal Po

1966

Other Studies

8 other studies available for fluorouracil and Intestinal Polyps

ArticleYear
Nuclear orphan receptor NR4A2 confers chemoresistance and predicts unfavorable prognosis of colorectal carcinoma patients who received postoperative chemotherapy.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:16

    Topics: Adenoma; Adenomatous Polyposis Coli; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biom

2013
Transanal endoscopic microsurgery with entrance into the peritoneal cavity: is it safe?
    Diseases of the colon and rectum, 2014, Volume: 57, Issue:10

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anal Canal; Antimetabolites, Antineoplastic; Blood Loss, Su

2014
Hepatocyte nuclear factor-4alpha promotes gut neoplasia in mice and protects against the production of reactive oxygen species.
    Cancer research, 2010, Nov-15, Volume: 70, Issue:22

    Topics: Adenoma; Animals; Antimetabolites, Antineoplastic; Colonic Neoplasms; Female; Fluorouracil; Gene Exp

2010
Remission of metastatic adenocarcinoma of the colon.
    JAMA, 1983, Nov-11, Volume: 250, Issue:18

    Topics: Adenocarcinoma; Adult; BCG Vaccine; Colonic Neoplasms; Female; Fluorouracil; Humans; Intestinal Poly

1983
Cancer of the colon and rectum. A review.
    Postgraduate medicine, 1975, Volume: 57, Issue:4

    Topics: Barium Sulfate; Carcinoembryonic Antigen; Colonic Neoplasms; Cystadenoma; Electrocoagulation; Fiber

1975
[Practice in the treatment of rectal carcinoma. Recommendations of the Deutschen Gesellschaft für Chirurgie].
    Medizinische Klinik, 1977, Dec-02, Volume: 72, Issue:48

    Topics: Anus Neoplasms; Female; Fluorouracil; Germany, West; Humans; Intestinal Polyps; Male; Neoplasm Metas

1977
Disappearance of hyperplastic polyposis after resection of rectal cancer. Report of two cases.
    Diseases of the colon and rectum, 1991, Volume: 34, Issue:9

    Topics: Adenocarcinoma; Aged; Anastomosis, Surgical; Brachytherapy; Colonic Neoplasms; Colonoscopy; Combined

1991
[The reactivity of the RES in cancer of the gastrointestinal tract and during treatment with fluorofur].
    Voprosy onkologii, 1972, Volume: 18, Issue:12

    Topics: Achlorhydria; Adult; Aged; Colonic Neoplasms; Esophageal Neoplasms; Female; Fluorouracil; Furans; Go

1972