Page last updated: 2024-10-27

fluorouracil and Insulin Resistance

fluorouracil has been researched along with Insulin Resistance in 2 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benko, I1
Djazayeri, K1
Abrahám, C1
Zsuga, J1
Szilvássy, Z1
Zarowitz, H1

Other Studies

2 other studies available for fluorouracil and Insulin Resistance

ArticleYear
Rosiglitazone-induced protection against myelotoxicity produced by 5-fluorouracil.
    European journal of pharmacology, 2003, Sep-12, Volume: 477, Issue:2

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Bone Marrow; Bone Marrow Cells; Colo

2003
Postpancreatectomy insulin-resistant diabetes mellitus. Improvement after prednisone and 5-fluorouracil.
    New York state journal of medicine, 1972, Dec-15, Volume: 72, Issue:24

    Topics: Diabetes Mellitus; Female; Fluorouracil; Humans; Insulin Resistance; Middle Aged; Pancreatectomy; Pa

1972