Page last updated: 2024-10-27

fluorouracil and Injuries, Tendon

fluorouracil has been researched along with Injuries, Tendon in 13 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's6 (46.15)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fatemi, MJ1
Shirani, S1
Sobhani, R1
Lebaschi, AH1
Gharegozlou, MJ1
Bagheri, T1
Pedram, M1
Saberi, M1
Araghi, S1
Fatemi, MA1
Duci, SB1
Arifi, HM1
Ahmeti, HR1
Manxhuka-Kerliu, S1
Neziri, B1
Mekaj, AY1
Lajqi, S1
Shahini, L1
Guo, M2
Zhang, J2
Tian, D2
Zhang, Y1
Peng, X1
Wang, Z1
Wu, J1
Duan, Y1
Dou, Z1
Wang, C1
Zhao, C1
Zobitz, ME1
Sun, YL1
Predmore, KS1
Amadio, PC1
An, KN1
Moran, SL2
Sheng, J1
Zeng, B1
Jiang, P1
Fan, C1
McGonagle, L1
Jones, MD1
Dowson, D1
Theobald, PS1
Karaaltin, MV1
Ozalp, B1
Dadaci, M1
Kayikcioglu, A1
Kecik, A1
Oner, F1
Khan, U3
Occleston, NL1
Khaw, PT2
McGrouther, DA3
Akali, A3
McGrouther, AD1
Ryan, CK1
Orlando, GS1
Pratt, CE1
Michalko, KB1
Kakar, S1
Bentley, G1
Cerovac, S1
Afoke, A1

Trials

1 trial available for fluorouracil and Injuries, Tendon

ArticleYear
[Effects of 5-fluorouracil on tendon adhesion formation after flexor tendon repair].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2008, Volume: 22, Issue:7

    Topics: Adult; Female; Finger Injuries; Fluorouracil; Humans; Male; Plastic Surgery Procedures; Tendon Injur

2008

Other Studies

12 other studies available for fluorouracil and Injuries, Tendon

ArticleYear
Prevention of Peritendinous Adhesion Formation After the Flexor Tendon Surgery in Rabbits: A Comparative Study Between Use of Local Interferon-α, Interferon-β, and 5-Fluorouracil.
    Annals of plastic surgery, 2018, Volume: 80, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Biomechanical Phenomena; Fluorouracil; Interferon-alpha; Interfer

2018
Biomechanical and Macroscopic Evaluations of the Effects of 5-Fluorouracil on Partially Divided Flexor Tendon Injuries in Rabbits.
    Chinese medical journal, 2015, Jun-20, Volume: 128, Issue:12

    Topics: Animals; Fluorouracil; Male; Rabbits; Tendon Injuries; Tendons; Tissue Adhesions; Wound Healing

2015
Surface treatment with 5-fluorouracil after flexor tendon repair in a canine in vivo model.
    The Journal of bone and joint surgery. American volume, 2009, Volume: 91, Issue:11

    Topics: Administration, Topical; Animals; Antimetabolites; Dogs; Fluorouracil; Musculoskeletal Diseases; Ten

2009
[Effect of local basic fibroblast growth factor and 5-fluorouracil on accelerating healing and preventing tendon adhesion after flexor tendon repair].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2011, Volume: 25, Issue:6

    Topics: Animals; Biomechanical Phenomena; Chickens; Fibrin Tissue Adhesive; Fibroblast Growth Factor 2; Fluo

2011
The bio-tribological properties of anti-adhesive agents commonly used during tendon repair.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2012, Volume: 30, Issue:5

    Topics: Animals; Carbohydrates; Cattle; Fluorouracil; Hyaluronic Acid; Polymers; Sodium Chloride; Synovial F

2012
The effects of 5-fluorouracil on flexor tendon healing by using a biodegradable gelatin, slow releasing system: experimental study in a hen model.
    The Journal of hand surgery, European volume, 2013, Volume: 38, Issue:6

    Topics: Absorbable Implants; Animals; Antimetabolites, Antineoplastic; Casts, Surgical; Chickens; Delayed-Ac

2013
[An effect of 5-fluorouracil on tendon adhesion formation after flexor tendon repair in chickens].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2007, Volume: 21, Issue:8

    Topics: Administration, Topical; Animals; Biomechanical Phenomena; Chickens; Fluorouracil; Male; Postoperati

2007
Single exposures to 5-fluorouracil: a possible mode of targeted therapy to reduce contractile scarring in the injured tendon.
    Plastic and reconstructive surgery, 1997, Volume: 99, Issue:2

    Topics: Animals; Antimetabolites; Cells, Cultured; Cicatrix; Collagen; Cytoskeleton; Fibroblasts; Fluorourac

1997
Decrease in adhesion formation by a single application of 5-fluorouracil after flexor tendon injury.
    Plastic and reconstructive surgery, 1999, Volume: 103, Issue:1

    Topics: Animals; Antimetabolites; Fluorouracil; Foot; Hindlimb; Male; Postoperative Complications; Rabbits;

1999
Effects of 5-fluorouracil on flexor tendon repair.
    The Journal of hand surgery, 2000, Volume: 25, Issue:2

    Topics: Administration, Topical; Analysis of Variance; Animals; Antimetabolites, Antineoplastic; Biomechanic

2000
Modulation of the formation of adhesions during the healing of injured tendons.
    The Journal of bone and joint surgery. British volume, 2000, Volume: 82, Issue:7

    Topics: Animals; Cell Count; Disease Models, Animal; Fibroblasts; Fluorouracil; Hindlimb; Immunosuppressive

2000
Early breaking strength of repaired flexor tendon treated with 5-fluorouracil.
    Journal of hand surgery (Edinburgh, Scotland), 2001, Volume: 26, Issue:3

    Topics: Animals; Fluorouracil; Male; Rabbits; Sutures; Tendon Injuries; Tensile Strength; Tissue Adhesions;

2001