Page last updated: 2024-10-27

fluorouracil and Injuries, Radiation

fluorouracil has been researched along with Injuries, Radiation in 175 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Radiation enteritis is the main acute side-effect during pelvic irradiation."5.34Dose-volume relationships between enteritis and irradiated bowel volumes during 5-fluorouracil and oxaliplatin based chemoradiotherapy in locally advanced rectal cancer. ( Bendahl, PO; Gunnlaugsson, A; Johnsson, A; Kjellén, E; Nilsson, P; Willner, J, 2007)
"This article describes a woman with metastatic upper gastrointestinal cancer who developed thoracic myelopathy unexpectedly after standard dosage and fractionation radiotherapy."5.33Myelopathy after radiation therapy and chemotherapy with capecitabine and gemcitabine. ( Barstis, JL; Black, AC, 2005)
"In this phase I study, we sought to determine the feasibility and tolerability of neoadjuvant short course radiotherapy (SC-CRT) delivered with photon RT with concurrent capecitabine for resectable pancreatic adenocarcinoma."5.19Phase I study of neoadjuvant accelerated short course radiation therapy with photons and capecitabine for resectable pancreatic cancer. ( Ancukiewicz, M; Blaszkowsky, LS; Fernandez-del Castillo, C; Ferrone, CR; Hong, TS; Kwak, EL; Lillemoe, KD; Mamon, HJ; Napolitano, BN; Ryan, DP; Swanson, RS; Tseng, YD; Wo, JY, 2014)
"A multi-institutional phase 2 trial assessed the utility of dose-painted intensity modulated radiation therapy (DP-IMRT) in reducing grade 2+ combined acute gastrointestinal and genitourinary adverse events (AEs) of 5-fluorouracil (5FU) and mitomycin-C (MMC) chemoradiation for anal cancer by at least 15% compared with the conventional radiation/5FU/MMC arm from RTOG 9811."5.17RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal. ( Esthappan, J; Goodyear, MD; Haddock, MG; Kachnic, LA; Myerson, RJ; Parikh, PJ; Rotman, M; Safran, H; Willett, CG; Willins, J; Winter, K, 2013)
"Radiation Therapy Oncology Group (RTOG) 92-08 began as a single arm, Phase II trial for patients with anal cancer consisting of radiation (RT) + 5-flourouracil + mitomycin-C with a mandatory 2-week break and was amended after completion to evaluate the same treatment regimen without a treatment break."5.13Evaluation of planned treatment breaks during radiation therapy for anal cancer: update of RTOG 92-08. ( Garcia, M; John, M; Konski, A; Krieg, R; Myerson, R; Pinover, W; Willett, C, 2008)
" Two patients with nasopharyngeal carcinoma complicated by collagen diseases (dermatomyositis in one, and Sjögren's syndrome with mixed connective tissue disease in the other) were given radiotherapy combined with chemotherapy consisting of cis-platinum and 5-fluorouracil."4.79Retropharyngeal abscess after radiation therapy and cis-platinum, 5-fluorouracil treatment for nasopharyngeal carcinoma with collagen disease: report of two patients and a review of the literature. ( Asakura, K; Hareyama, M; Hattori, A; Horikoshi, T; Hyodo, K; Imai, K; Koshiba, H; Morita, K; Nagakura, H; Oouchi, A; Sakata, K; Shido, M; Tamakawa, M; Tanaka, S, 1996)
"During a regular MR control, the patient developed anaphylactic reaction to Gadolinium, and after that a rectosigmoid ischemia with total necrosis of the posterior rectal wall was diagnosed and surgically treated with Hartmann procedure."3.91Hypovolemic shock after pelvic radiotherapy. A rare combination leading to a devastating complication. ( Calvisi, G; Carlei, F; Di Sibio, A; Di Staso, M; Giuliani, A; Lombardi, L; Marchese, M; Romano, L; Romanzi, F; Schietroma, M, 2019)
"From March 2009 through April 2012, 22 patients were treated with proton therapy and concomitant capecitabine (1000 mg PO twice daily) for resected (n = 5); marginally resectable (n = 5); and unresectable/inoperable (n = 12) biopsy-proven pancreatic and ampullary adenocarcinoma."3.79Proton therapy with concomitant capecitabine for pancreatic and ampullary cancers is associated with a low incidence of gastrointestinal toxicity. ( Asbun, HJ; Awad, ZT; George, TJ; Ho, MW; Hoppe, BS; Huh, S; Mendenhall, NP; Morris, CG; Nichols, RC; Zaiden, RA, 2013)
"A 61-year-old man, with a tuberous sclerosis, experienced severe acute reactions during a concomitant chemoradiotherapy regimen after 22Gy and one cycle of 5-fluorouracil-cisplatinum."3.79[Hypersensitivity to radiation therapy in a patient with tuberous sclerosis: biological considerations about a clinical case]. ( Baruch-Hennequin, V; Duchemain, B; Duchemann, B; Hennequin, C; Quero, L; Rivera, S; Wong, S, 2013)
"A 59-year-old patient with a coexisting primary choroidal melanoma and colorectal cancer was treated with external beam radiation (EBR) of his choroidal melanoma and systemic chemotherapy with leukovorin/5 fluorouracil (FU) for treatment of his metastatic colorectal cancer."3.74Regression of radiation-induced macular edema after systemic bevacizumab. ( Bakri, SJ; Pulido, JS; Solano, JM, 2007)
"Twenty-two patients with adenocarcinoma metastatic to the liver were treated with rapid fractionation whole-liver irradiation (1350-2100 rads in 300-rad fractions) with simultaneous intrahepatic 5-fluorouracil (10-15 mg/kg/day) and intrahepatic Adriamycin 2."3.66Combined modality therapy of hepatic metastasis. Northern California Oncology Group Pilot Study. ( Cassidy, M; Friedman, M; Levine, M; Phillips, T; Resser, KJ; Spivack, S, 1979)
"Radiation proctitis was identified by imaging in 9 (15."2.94Effect of interval between preoperative radiotherapy and surgery on clinical outcome and radiation proctitis in rectal cancer from FOWARC trial. ( Cheng, YK; Gao, X; Huang, XY; Lan, P; Ma, TH; Qin, QY; Wang, L, 2020)
"A challenge in borderline resectable pancreatic cancer (BRPC) management is the high rate of positive posterior margins (PM)."2.82A Phase 1 Study of Stereotactic Body Radiation Therapy Dose Escalation for Borderline Resectable Pancreatic Cancer After Modified FOLFIRINOX (NCT01446458). ( Brutcher, E; Cassidy, RJ; Chen, Z; El-Rayes, BF; Hawk, N; Kooby, D; Landry, J; Maithel, SK; Sarmiento, JM; Shaib, WL; Zhang, C, 2016)
"The rates of anastomotic leakage and stenosis were calculated for each treatment arm."2.82Impact of Preoperative Radiotherapy on Anastomotic Leakage and Stenosis After Rectal Cancer Resection: Post Hoc Analysis of a Randomized Controlled Trial. ( Deng, Y; Ma, T; Qin, Q; Wang, H; Wang, J; Wang, L; Zheng, J; Zhou, Z, 2016)
"From 1990-2006, 100 patients with nasopharyngeal cancer were treated with alternating chemoradiation at the Aichi Cancer Center."2.78Alternating chemoradiotherapy in patients with nasopharyngeal cancer: prognostic factors and proposal for individualization of therapy. ( Fuwa, N; Goto, Y; Kodaira, T; Mizoguchi, N; Nakahara, R; Nomura, M; Tachibana, H; Tomita, N, 2013)
"Fifty-eight anal cancer patients were treated with concurrent chemotherapy and IMRT."2.78Dosimetric parameters predictive of acute gastrointestinal toxicity in patients with anal carcinoma treated with concurrent chemotherapy and intensity-modulated radiation therapy. ( Beriwal, S; DeFoe, SG; Heron, DE; Kabolizadeh, P, 2013)
"Deleterious oral mucositis (OM) develops during radiotherapy (RT) or chemoradiotherapy for head-and-neck cancer (HNC) patients."2.77Phenylbutyrate mouthwash mitigates oral mucositis during radiotherapy or chemoradiotherapy in patients with head-and-neck cancer. ( Chung, YL; Jen, YM; Lin, YH; Wang, LW; Yen, SH, 2012)
" Toxicity was monitored according to Common Terminology Criteria for Adverse Events."2.77Acute toxicity of radiochemotherapy in rectal cancer patients: a risk particularly for carriers of the TGFB1 Pro25 variant. ( Becker, H; Beissbarth, T; Brockmöller, J; Christiansen, H; Conradi, LC; Gaedcke, J; Ghadimi, M; Hennies, S; Herrmann, MK; Hess, CF; Jo, P; Mergler, CP; Rave-Fränk, M; Schirmer, MA; Wolff, HA, 2012)
"Radiation injuries were reported in 37."2.75[Extended preoperative course of radiotherapy as component of combined and complex treatment of locally-advanced ampular rectal cancer]. ( Lukina, EIu; Nadvikova, EA; Semikopov, KV; Vazhenin, AV, 2010)
"Recommended dosage for future trials is capecitabine 625 mg/m bid, irinotecan 35 mg/m, and celecoxib 400 mg orally bid in combination with pelvic radiation."2.75A phase I study of capecitabine, irinotecan, celecoxib, and radiation as neoadjuvant therapy of patients with locally advanced rectal cancer. ( Alqaisi, M; Bernal, P; Bush, D; Byrd, J; Garberoglio, C; Hussein, F; Malik, I, 2010)
"50 patients with squamous cell carcinoma (90%) or adenocarcinoma and mostly advanced tumor stage were treated (82% T3/T4 and 70% N1)."2.73Esophageal cancer. A prospective phase II study of concomitant-boost external-beam chemoradiation with a top-up endoluminal boost. ( Brunner, TB; Grabenbauer, GG; Melzner, W; Rupp, A; Sauer, R, 2008)
"Capecitabine was given twice daily, 7 days a week at a dose starting at 350 mg/m(2) bid."2.71Results of a phase I study to determine the maximum tolerated dose of capecitabine when given concurrently with radical radiotherapy in the treatment of squamous cell carcinoma of the head and neck. ( Ironside, JA; MacDougall, RH; Mais, KL; Slevin, NJ; Sykes, AJ, 2004)
"Neutropenia was the only grade-4 toxicity that occurred in 2 patients."2.71Phase II trial of hyperfractionated accelerated split-course radiochemotherapy with 5-FU and Cis-DDP in advanced head and neck cancer: results and toxicity. ( Ernst-Stecken, A; Grabenbauer, G; Iro, H; Plasswilm, L; Sauer, R, 2004)
"Treatment with sodium selenite is well tolerated and easy to deliver."2.71Selenium in the treatment of radiation-associated secondary lymphedema. ( Bruns, F; Büntzel, J; DeVries, AF; Glatzel, M; Kisters, K; Micke, O; Mücke, R; Schäfer, U; Schönekaes, K, 2003)
"Distant metastases remain the main cause of treatment failure in NPC."2.70Neoadjuvant chemotherapy plus conventional radiotherapy or accelerated hyperfractionation in stage III and IV nasopharyngeal carcinoma--a phase II study. ( Allam, A; El-Badawi, S; El-Serafi, M; El-Weshi, A; Ibrahim, E; Khafaga, Y; Mosseri, V, 2001)
" 5-FU chemotherapy was administered as 120-hours continuous infusion in the first and fifth radiation week via a central venous catheter in a daily dosage of 1,000 mg/m2."2.69Intermittent use of amifostine during postoperative radiochemotherapy and acute toxicity in rectal cancer patients. ( Dunst, J; Müller, AC; Pigorsch, S; Reese, T; Semlin, S, 2000)
"Fibrosis was estimated by palpation in 404 patients by four physicians."2.67Dose and volume effects on fibrosis after breast conservation therapy. ( Bartelink, H; Borger, JH; Hart, A; Kemperman, H; Lebesque, J; Smitt, HS; van Dongen, J, 1994)
"Radiation complications included pneumonitis three of 30 (10%) and esophagitis (27%)."2.66Concomitant 5-fluorouracil infusion and high-dose radiation for stage III non-small cell lung cancer. ( Chaffey, J; Lokich, J; Neptune, W, 1989)
"Pursuant to this, the North Central Cancer Treatment Group has developed a series of clinical trials designed to study antidotes for these pathologic processes."2.39Alleviation of cytotoxic therapy-induced normal tissue damage. ( Foote, RL; Loprinzi, CL; Michalak, J, 1995)
"Of the 13,499 patients with ulcerative colitis treated, 17 adult patients with ulcerative colitis and anal dysplasia and/or anal squamous cell carcinoma were included in the study: 6 had a diagnosis of anal squamous cell carcinoma, 8 had high-grade squamous intraepithelial lesions, and 3 had low-grade squamous intraepithelial lesions."1.62Anal Squamous Cell Carcinoma in Ulcerative Colitis: Can Pouches Withstand Traditional Treatment Protocols? ( Click, B; Hull, TL; Lightner, AL; McMichael, J; Regueiro, M; Steele, SR; Vaidya, P, 2021)
"Our results suggest that the use of IMRT decreases acute and chronic adverse effects although reduced QoL also occurred in the IMRT group."1.51Chemoradiation in female patients with anal cancer: Patient-reported outcome of acute and chronic side effects. ( Adeberg, S; Debus, J; Haefner, MF; Herfarth, K; Koerber, SA; Krug, D; Liermann, J; Seither, B; Slynko, A; Sterzing, F, 2019)
" Patient acute gastrointestinal toxicity was recorded using Common Terminology Criteria of Adverse Events (CTCAE) diarrhoea grading."1.48Intensity-modulated Radiotherapy for Anal Cancer: Dose-Volume Relationship of Acute Gastrointestinal Toxicity and Disease Outcomes. ( Amor, H; Blakey, D; Chao, M; Guerrieri, M; Guiney, M; Ho, H; Macleod, C; Melven, L; Ng, M; Skelton, J; Subramanian, B, 2018)
"To investigate the association between polymorphisms of DNA repair genes and xenobiotic with acute adverse effects in locally advanced rectal cancer patients treated with neoadjuvant radiochemotherapy."1.46Potential Role of Single Nucleotide Polymorphisms of XRCC1, XRCC3, and RAD51 in Predicting Acute Toxicity in Rectal Cancer Patients Treated With Preoperative Radiochemotherapy. ( Agolli, L; Borro, M; Bracci, S; De Sanctis, V; Di Nardo, F; Enrici, RM; Falco, T; Gentile, G; Maglio, M; Minniti, G; Nicosia, L; Osti, MF; Simmaco, M; Valeriani, M, 2017)
"The study included 127 gastric cancer patients, who underwent preoperative or postoperative chemoradiotherapy."1.43Radiation-induced injury of the exocrine pancreas after chemoradiotherapy for gastric cancer. ( Maslyk, B; Polanowski, P; Tukiendorf, A; Wydmanski, J, 2016)
"Lobaplatin plus 5-Fu combined with concurrent radiotherapy is safe and effective in treating patients with middle-advanced stage esophageal cancer."1.42Clinical Study on Lobaplatin Combined with 5-Fu and Concurrent Radiotherapy in Treating Patients with Inoperable Esophageal Cancer. ( Huang, JZ; Jia, XJ, 2015)
"Radiotherapy for rectal cancer patients may induce late pelvic complications as time progresses, and irreversible tissue changes due to radiation could disrupt the successful treatment of radiation-related complications."1.40Late complications after proctectomy in rectal cancer patients who underwent radiotherapy. ( Jung, SH; Kim, JH; Kim, SH, 2014)
"A 57-year-old Hispanic male with pancreatic cancer initially received 7 cycles of FOLFIRINOX followed by capecitabine with radiation therapy for 28 fractions for a total of 5,040 cGy."1.40Radiation recall gastritis secondary to erlotinib in a patient with pancreatic cancer. ( Graziani, C; Hegde, S; Saif, MW, 2014)
"The treatment of anal cancer is based on concomitant radiotherapy and chemotherapy and is associated with a nonnegligible rate of local severe toxicities that can strongly impair the quality of life."1.39Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy. ( Benezery, K; Doyen, J; Follana, P; Francois, E; Gal, J; Gérard, JP; Hannoun-Levi, JM; Ortholan, C, 2013)
"Locoregional treatment of inflammatory breast cancer (IBC) is crucial because local relapses may be highly symptomatic and are commonly associated with distant metastasis."1.38Exclusive alternating chemotherapy and radiotherapy in nonmetastatic inflammatory breast cancer: 20 years of follow-up. ( Arriagada, R; Bourgier, C; Dunant, A; Heymann, S; Marsiglia, H; Mathieu, MC; Pessoa, EL; Spielmann, M; Uzan, C, 2012)
"The optimal dosage and frequency of platinum-based chemoradiotherapy (CRT) regimen for treating advanced head and neck squamous cell carcinoma remains unresolved."1.38Comparison of acute toxicities in two primary chemoradiation regimens in the treatment of advanced head and neck squamous cell carcinoma. ( Best, SR; Blanco, RG; Califano, JA; Fan, KY; Gogineni, H; Ha, PK; Lake, S; Levine, MA; Messing, B; Pai, SI; Saunders, JR; Tang, M; Zaboli, D; Zahurak, ML; Zinreich, ES, 2012)
"The records of 96 patients treated for cervical cancer from 2006 to 2010 were retrospectively reviewed."1.38Low-dose-rate californium-252 neutron intracavitary afterloading radiotherapy combined with conformal radiotherapy for treatment of cervical cancer. ( Lin, S; Liu, JR; Pan, SD; Xu, HD; Yue, JH; Zhang, M, 2012)
"Pemphigus is an autoimmune intraepidermal blistering disease mediated by autoantibodies targeting desmosomes."1.37Radiotherapy-induced pemphigus vulgaris with autoantibodies targeting a 110 kDa epidermal antigen. ( Badri, T; Benmously-Mlika, R; Fenniche, S; Hammami, H; Lachkham, A; Mokhtar, I, 2011)
"The global health QoL of anal cancer patients is comparable with that of the general German population, but there are specific limitations, e."1.37Quality of life outcomes in patients with anal cancer after combined radiochemotherapy. ( Hägele, V; Mai, SK; Welzel, G; Wenz, F, 2011)
"Strictures were associated with tumor location (tonsil vs base of tongue; p = ."1.37Factors associated with pharyngoesophageal stricture in patients treated with concurrent chemotherapy and radiation therapy for oropharyngeal squamous cell carcinoma. ( Best, SR; Blanco, RG; Califano, JA; Ha, PK; Levine, MA; Messing, BP; Murakami, P; Pai, SI; Saunders, JR; Thompson, R; Trachta, J; Ulmer, K; Walker, M; Zinreich, ES, 2011)
"Forty-seven patients with head and neck cancers who underwent definitive chemoradiotherapy between December 1998 and March 2006 were reviewed retrospectively."1.36Validation of the Total Dysphagia Risk Score (TDRS) as a predictive measure for acute swallowing dysfunction induced by chemoradiotherapy for head and neck cancers. ( Kadoya, M; Koiwai, K; Sasaki, S; Shikama, N; Shinoda, A, 2010)
"Unknown primary head and neck cancers often require comprehensive mucosal and bilateral neck irradiation."1.35Intensity-modulated radiotherapy for head and neck cancer of unknown primary: toxicity and preliminary efficacy. ( Klem, ML; Kraus, D; Lee, NY; Mechalakos, JG; Pfister, DG; Shah, J; Shaha, A; Singh, B; Wolden, SL; Zelefsky, MJ, 2008)
"Every 21 days, sequential surgery of breast carcinoma, adjuvant chemotherapy FAC and irradiation."1.35[Risk of cardiotoxicity of combination treatment radiotherapy and chemotherapy of locally advanced breast carcinoma stage III]. ( Bustová, I, 2009)
"Sixty consecutive patients treated for gastric cancer either with 3D-CRT (n = 27) and IMRT (n = 33) were evaluated."1.35Combined adjuvant radiochemotherapy with IMRT/XELOX improves outcome with low renal toxicity in gastric cancer. ( Boda-Heggemann, J; Hermes, P; Hieber, U; Hochhaus, A; Hofheinz, RD; Lohr, F; Mai, SK; Massner, B; Mennemeyer, P; Post, S; Weiss, C; Wenz, F; Wertz, H, 2009)
" Five cardiopulmonary toxic events of Grade 3 or greater were observed in 4 patients, Grade 5 heart failure and Grade 3 pericarditis in 1 patient, and Grade 3 myocardial infarction, Grade 3 radiation pneumonitis, and Grade 3 pleural effusion."1.35Late toxicity after definitive concurrent chemoradiotherapy for thoracic esophageal carcinoma. ( Chin, K; Gomi, K; Ito, H; Kozuka, T; Matsuura, M; Morota, M; Oguchi, M; Yamashita, T, 2009)
"Fertility preservation in women with rectal cancer is feasible."1.35Fertility preservation for young women with rectal cancer--a combined approach from one referral center. ( Elizur, SE; Huang, JY; Levin, D; Meterissian, S; Tan, SL; Tulandi, T, 2009)
"Radiation enteritis is the main acute side-effect during pelvic irradiation."1.34Dose-volume relationships between enteritis and irradiated bowel volumes during 5-fluorouracil and oxaliplatin based chemoradiotherapy in locally advanced rectal cancer. ( Bendahl, PO; Gunnlaugsson, A; Johnsson, A; Kjellén, E; Nilsson, P; Willner, J, 2007)
"This article describes a woman with metastatic upper gastrointestinal cancer who developed thoracic myelopathy unexpectedly after standard dosage and fractionation radiotherapy."1.33Myelopathy after radiation therapy and chemotherapy with capecitabine and gemcitabine. ( Barstis, JL; Black, AC, 2005)
"As patients with oesophageal cancer have a high incidence of co-morbidities including cardiac problems, the aim of this paper was to quantify the extent of cardiac radiation and discuss the influence of beam arrangement to reduce this."1.33Quantification and reduction of cardiac dose in radical radiotherapy for oesophageal cancer. ( Cominos, M; Cornes, P; Henrys, A; Mosleh-Shirazi, MA; Tait, D, 2005)
" Patients in the P+M group who received a 5-fluorouracil (5-FU) dosage of more than 3500 mg had a better 5-year local control rate than patients who received a 5-FU dosage of less than 3500 mg (p = 0."1.31Trimodal combination therapy for maxillary sinus carcinoma. ( Amagasa, T; Enomoto, S; Kishimoto, S; Miura, M; Ogura, I; Shibuya, H; Yoshimura, R, 2002)
"There was no clinical evidence of carcinoid syndrome."1.255-Hydroxyindole-secreting rectal carcinoid tumour. ( Cheetham, HD; Murray-Lyon, IM; Sandler, M; Watts, JA; Williams, R, 1972)

Research

Studies (175)

TimeframeStudies, this research(%)All Research%
pre-199022 (12.57)18.7374
1990's19 (10.86)18.2507
2000's56 (32.00)29.6817
2010's74 (42.29)24.3611
2020's4 (2.29)2.80

Authors

AuthorsStudies
Hennequin, C3
Guillerm, S1
Quero, L3
Cheng, YK1
Qin, QY1
Huang, XY1
Lan, P1
Wang, L3
Gao, X1
Ma, TH1
Smart, AC1
Goyal, L1
Horick, N1
Petkovska, N1
Zhu, AX1
Ferrone, CR2
Tanabe, KK1
Allen, JN1
Drapek, LC1
Qadan, M1
Murphy, JE1
Eyler, CE1
Ryan, DP2
Hong, TS2
Wo, JY2
Sauter, M1
Lombriser, N1
Bütikofer, S1
Keilholz, G1
Kranzbühler, H1
Heinrich, H1
Rogler, G1
Vavricka, SR1
Misselwitz, B1
Ye, W1
Shi, L1
Qian, L1
Sun, Y1
Sun, X1
Lightner, AL1
Vaidya, P1
McMichael, J1
Click, B1
Regueiro, M1
Steele, SR1
Hull, TL1
Park, JJ1
Hajj, C1
Reyngold, M1
Shi, W1
Zhang, Z1
Cuaron, JJ1
Crane, CH3
O'Reilly, EM1
Lowery, MA1
Yu, KH1
Goodman, KA2
Wu, AJ1
Matsumoto, Y1
Zhou, Q1
Kamimura, K1
Moriyama, M1
Saijo, Y1
Ng, M1
Ho, H1
Skelton, J1
Guerrieri, M1
Guiney, M1
Chao, M1
Blakey, D1
Macleod, C1
Amor, H1
Subramanian, B1
Melven, L1
Li, Y2
Xu, T1
Qian, W1
Lu, X1
Hu, C1
Lu, L1
Sheng, Y1
Zhang, G1
OuYang, PY1
Ge, Y1
Xie, T1
Chang, H1
Deng, X1
Wu, JQ1
Koerber, SA1
Seither, B1
Slynko, A1
Haefner, MF1
Krug, D2
Liermann, J1
Adeberg, S1
Herfarth, K1
Debus, J1
Sterzing, F1
Hojo, H1
Dohmae, T1
Hotta, K1
Kageyama, SI1
Baba, H1
Kohno, R1
Motegi, A1
Tsuchihara, K1
Akimoto, T1
Wu, L1
Chung, YL2
Hayashi, Y1
Iijima, H1
Isohashi, F1
Tsujii, Y1
Fujinaga, T1
Nagai, K1
Yoshii, S1
Sakatani, A1
Hiyama, S1
Shinzaki, S1
Makino, T1
Yamasaki, M1
Ogawa, K1
Doki, Y1
Takehara, T1
Monma, S1
Kato, K1
Shouji, H1
Okita, N1
Takashima, A1
Honma, Y1
Iwasa, S2
Hamaguchi, T1
Yamada, Y1
Shimada, Y1
Boku, N2
Nagashima, K1
Ito, Y2
Itami, J1
Giuliani, A1
Romanzi, F1
Di Sibio, A1
Calvisi, G1
Lombardi, L1
Marchese, M1
Di Staso, M1
Schietroma, M1
Carlei, F1
Romano, L1
Nichols, RC1
George, TJ1
Zaiden, RA1
Awad, ZT1
Asbun, HJ1
Huh, S1
Ho, MW1
Mendenhall, NP1
Morris, CG1
Hoppe, BS1
Mayahara, H1
Tanaka, T1
Wong, S2
DeFoe, SG1
Kabolizadeh, P1
Heron, DE1
Beriwal, S1
Huddart, RA1
Hall, E1
Hussain, SA1
Jenkins, P1
Rawlings, C1
Tremlett, J1
Crundwell, M1
Adab, FA1
Sheehan, D1
Syndikus, I1
Hendron, C1
Lewis, R1
Waters, R1
James, ND1
Doyen, J1
Benezery, K1
Follana, P1
Ortholan, C2
Gérard, JP1
Hannoun-Levi, JM1
Gal, J1
Francois, E1
Badakhshi, H2
Gruen, A1
Graf, R1
Boehmer, D2
Budach, V2
Mamon, HJ1
Blaszkowsky, LS1
Kwak, EL1
Tseng, YD1
Napolitano, BN1
Ancukiewicz, M1
Swanson, RS1
Lillemoe, KD1
Fernandez-del Castillo, C1
Becker, ET1
Jahn, U1
Wernecke, KD1
Stromberger, C1
Call, JA1
Prendergast, BM1
Jensen, LG1
Ord, CB1
Jacob, R1
Mell, LK1
Thomas, CR2
Jabbour, SK1
Miller, RC1
Lento, W1
Ito, T1
Zhao, C1
Harris, JR1
Huang, W2
Jiang, C1
Owzar, K1
Piryani, S1
Racioppi, L1
Chao, N1
Reya, T1
Kim, SH1
Kim, JH2
Jung, SH1
Trip, AK1
Nijkamp, J1
van Tinteren, H1
Cats, A1
Boot, H1
Jansen, EP1
Verheij, M1
Graziani, C1
Hegde, S1
Saif, MW1
Li, ZY1
Li, ZW1
Li, YH1
Sun, YS1
Ji, JF1
Gu, J1
Cai, Y1
Troussier, I1
Huguet, F1
Servagi-Vernat, S1
Benahim, C1
Khalifa, J1
Darmon, I1
Krebs, L1
Dejean, C1
Fenoglietto, P1
Vieillot, S1
Bensadoun, RJ1
Thariat, J1
Osti, MF1
Nicosia, L1
Agolli, L1
Gentile, G1
Falco, T1
Bracci, S1
Di Nardo, F1
Minniti, G1
De Sanctis, V1
Valeriani, M1
Maglio, M1
Borro, M1
Simmaco, M1
Enrici, RM1
Du, CR1
Ying, HM1
Kong, FF1
Zhai, RP1
Hu, CS1
Champ, CE1
Smith, RP1
Korytova, LI1
Sandalevskaya, AG1
Krasnikoval, VG1
Korytov, OV1
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Rashid, A1
Minsky, BD2
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Yao, JC1
Wolff, RA1
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Feig, BW2
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Wydmanski, J1
Polanowski, P1
Tukiendorf, A1
Maslyk, B1
Nakata, Y1
Ijichi, K1
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Hirakawa, H1
Kodaira, T2
Fujimoto, Y1
Fujii, T2
Miyazaki, T1
Shimizu, T1
Hasegawa, Y1
Shaib, WL1
Hawk, N1
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Sarmiento, JM1
Landry, J1
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Chen, NX1
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Qin, Q1
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Deng, Y1
Zheng, J1
Zhou, Z1
Wang, H1
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Häfner, MF1
Franco, P1
Ragona, R1
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Mistrangelo, M1
Cassoni, P1
Rondi, N1
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Yau, TK1
Chang, AT1
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Gomi, K1
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Lin, HQ1
Wei, YM1
Gong, HY1
Yi, Y1
Wang, LY1
Malik, I1
Hussein, F1
Bush, D1
Alqaisi, M1
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Garberoglio, C1
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Hakim, S1
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Rades, D2
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Gaedcke, J2
Jung, K2
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Rothe, H1
Schirmer, M2
Liersch, T1
Herrmann, MKA1
Hennies, S3
Rave-Fränk, M4
Hess, CF4
Christiansen, H3
Yang, GY1
May, KS1
Iyer, RV1
Chandrasekhar, R1
Wilding, GE1
McCloskey, SA1
Khushalani, NI1
Yendamuri, SS1
Gibbs, JF1
Fakih, M1
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Vazhenin, AV1
Nadvikova, EA1
Lukina, EIu1
Meyners, T1
Bohlen, G1
Kazic, N1
Hakim, SG1
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Shin, SK1
Kim, DY1
Isaev, PA1
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Herrmann, MK2
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Virsik, P1
Ghadimi, M2
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Ha, PK2
Blanco, RG2
Saunders, JR2
Zinreich, ES2
Levine, MA2
Pai, SI2
Walker, M1
Trachta, J1
Ulmer, K1
Murakami, P1
Thompson, R1
Califano, JA2
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Sawada, S1
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Wang, LW1
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Clinical Trials (22)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase I/II Study of Neoadjuvant Accelerated Short Course Radiation Therapy With Photons and Capecitabine for Resectable Pancreatic Cancer[NCT00889187]Phase 1/Phase 210 participants (Actual)Interventional2009-12-31Terminated (stopped due to Excess toxicity was identified intraoperatively)
Chemotherapy-based Split Stereotactic Body Radiation Therapy for Borderline Resectable and Locally Advanced Pancreatic Cancer: Study Protocol of a Prospective, Single-arm Phase II Trial[NCT04289792]Phase 227 participants (Anticipated)Interventional2020-05-09Recruiting
Phase I Study of Stereotactic Body Radiation Therapy and 5-Fluorouracil, Oxaliplatin and Irinotecan (FOLFIRINOX) in the Neoadjuvant Therapy of Pancreatic Cancer[NCT01446458]Phase 113 participants (Actual)Interventional2011-11-30Completed
A Phase II/III Randomized Controlled Study of Neoadjuvant FOLFOX6 Treatment With or Without Radiation Compared to 5-Fu Based Chemoradiation in Treating Patients With Resectable Rectal Cancer[NCT01211210]Phase 2/Phase 3495 participants (Actual)Interventional2010-06-30Active, not recruiting
Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy of Lower Rectal Cancer With Suspected Local Lymph Node Metastasis[NCT03587480]250 participants (Anticipated)Interventional2018-12-17Recruiting
Evaluation of Individual Radiosensitivity of Cancer Patients to be Treated by Radiotherapy or Radiochemotherapy Per-operative[NCT02797405]97 participants (Actual)Interventional2016-10-31Terminated (stopped due to Withdrawal of analysis study Partner.)
A Phase II Study Of Intensity Modulated Radiation Therapy (IMRT) +/- Chemotherapy For Nasopharyngeal Cancer[NCT00057785]Phase 268 participants (Actual)Interventional2003-02-28Completed
A Multicenter, Prospective, Randomized Controlled Clinical Trial Comparing Endostar With Concurrent Chemoradiotherapy and Concurrent Chemoradiotherapy in the Treatment of Locoregionally Advanced Nasopharyngeal Carcinoma (NPC)[NCT02907710]Phase 3300 participants (Anticipated)Interventional2016-10-31Not yet recruiting
Concurrent Chemoradiotherapy With Toripalimab for Local-regional Recurrent Nasopharyngeal Carcinoma: a Prospective, Single-arm, Phase II Trial[NCT04992988]Phase 240 participants (Anticipated)Interventional2020-06-28Recruiting
Toripalimab in Combination With Concurrent Chemoradiotherapy for Local-regional Recurrent Nasopharyngeal Carcinoma: a Phase 3, Multicentre, Randomised Controlled Trial[NCT04376866]Phase 3204 participants (Anticipated)Interventional2020-06-28Recruiting
Translational Validation Study to Examine KFO179-1 Biomarker Scores for the Prediction and Prognosis of Advanced Primary Resectable Rectal Cancer Stages UICC II-IV, With a 5-FU-based Standard Radiochemotherapy Followed by Total Mesorectal Excision.[NCT03034473]200 participants (Actual)Interventional2011-08-31Active, not recruiting
Quarterback 22: A Phase II Clinical Trial of Sequential Therapy and De-Intensified Chemoradiotherapy for Locally Advanced HPV Positive Oropharynx Cancer[NCT02945631]43 participants (Actual)Interventional2016-04-25Active, not recruiting
The Quarterback Trial: A Randomized Phase III Clinical Trial Comparing Reduced and Standard Radiation Therapy Doses for Locally Advanced HPV Positive Oropharynx Cancer[NCT01706939]Phase 323 participants (Actual)Interventional2012-09-01Active, not recruiting
Prospective Randomised Multicenter Phase-III-study: Preoperative Radiochemotherapy and Adjuvant Chemotherapy With 5-Fluorouracil Plus Oxaliplatin Versus Preoperative Radiochemotherapy and Adjuvant Chemotherapy With 5-Fluorouracil for Locally Advanced Rect[NCT00349076]Phase 31,256 participants (Actual)Interventional2006-07-31Completed
Randomized Controlled Trial of the Efficacy of Adjuvant Chemotherapy in Patients With Residual Lesions After Concurrent Radiochemotherapy for Locally Advanced Cervical Cancer[NCT04409860]120 participants (Anticipated)Interventional2020-05-26Recruiting
The Role of Sodium Selenite Supplementation in Patients With Locally Advanced Head and Neck Cancer Undergoing Concurrent Chemoradiotherapy[NCT05451576]60 participants (Anticipated)Interventional2020-08-12Recruiting
trūFreeze® Spray Cryotherapy Patient Registry[NCT01802203]275 participants (Actual)Observational [Patient Registry]2013-04-30Completed
Phase I Trial of Dose Escalated IMRT to the Para-aortic Nodes With Concurrent Cisplatin and Amifostine in Locally Advanced Cervical Cancer[NCT00137358]Phase 10 participants (Actual)InterventionalWithdrawn (stopped due to unable to obtain funding to conduct study)
Phase III Study Comparing Neoadjuvant Chemotherapy With Carboplatin and Paclitaxel Followed by Standard Therapy, With Standard Therapy Alone in Women With Cervical Cancer and Para Aortic Positive Lymph Node.[NCT03534713]Phase 3310 participants (Anticipated)Interventional2020-07-17Recruiting
Phase II Trial of Weekly Carboplatin-Paclitaxel Adjuvant Chemotherapy After Intensity Modulated Extended-field Chemoradiation in the Treatment of Locally Advanced Cervical Cancer With Para-aortic Positive Nodes[NCT04016142]Phase 221 participants (Actual)Interventional2020-07-15Active, not recruiting
A Study Using Photon/Proton Beam Radiation Therapy and Chemotherapy for Unresectable Carcinoma of the Pancreas[NCT00685763]13 participants (Actual)Interventional2008-03-31Completed
Sintilimab Plus Chemotherapy and Radiotherapy for Patients With Inoperable Pancreatic Cancer: a Single-arm, Exploratory, Phase II Trial[NCT06050317]Phase 225 participants (Anticipated)Interventional2023-08-18Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Dose Limiting Toxicity (DLT) [Phase I]

DLT occurring within 3 weeks of the start of chemoradiation therapy was defined as: Grade 3 non-hematologic or hematologic toxicity requiring interruption of >7 days (d) of chemo or >3d chemoradiation; Grade 4 non-hematologic; Grade 4 neutropenia or thrombocytopenia; Treatment-related death; Delays in surgery >3 weeks due to treatment-related toxicity. A 30% increase in any surgical complication rate beyond those previously established rates (readmission rate: 16%; pancreatic fistula/intra-abdominal abscess/infection rate: 27%, major intra-abdominal bleeding requiring return to OR: 1.6%, delayed gastric emptying: 4.4%, and superficial wound infection rate: 8%) was also considered a DLT. (NCT00889187)
Timeframe: within 3 weeks of the start of chemoradiation therapy

Interventionpatients with DLT (Number)
Phase 1 Cohort 1: Photon Rad (30 Gy/12 Days)+Capecitabine0
Phase I Cohort 2: Photon Rad (25 Gy/11 Days)+Capecitabine0
Phase I Cohort 3: Photon Rad (25 Gy/5 Days)+Capecitabine0

Neoadjuvant Short-Course Photon Radiation Therapy Maximum Tolerated Dose (MTD) [Phase I]

Neoadjuvant short-course photon radiation therapy MTD in combination with capecitabine 825 mg/m2 orally BID for ten consecutive weekdays, beginning on the morning of the first day of radiation therapy is determined by the number of patients who experience a dose limiting toxicity (DLT). See subsequent primary outcome measure for the DLT definition. The MTD is defined as the highest dose at which fewer than one-third of patients experience a DLT. If none of 3 initial patients or only 1 of 6 patients have a DLT on dose level 3 then 6 additional patients are treated at this dose. If during this expansion, the rate of DLT exceeds 30% then the next lower dose level is declared the MTD. If no DLTs are observed, the MTD is not reached. (NCT00889187)
Timeframe: within 3 weeks of the start of chemoradiation therapy

InterventionGy per fraction (Number)
All Phase I: Photon Rad+CapecitabineNA

Protocol Compliance of Intensity-modulated Radiotherapy Treatment Delivered

Patients scored by the study chairs as no variation or minor variation were considered compliant, while patients scored as major variation or inevaluable were considered non-compliant. The number being reported is the number non-compliant. A compliance rate of 90% was targeted with 75% or lower being considered unacceptable. Fifty-seven patients were required with types I and II error rates both 0.10. If 10 or more patients out of 57 were non-compliant, the treatment would be unacceptable, per a two-stage Fleming multiple testing procedure. (NCT00057785)
Timeframe: From start of treatment to end of treatment

Interventionparticipants (Number)
IMRT +/- Chemotherapy9

Biomarkers Predictive of Failure

To determine biomarkers predictive of failure with either reduced or standard dose radiotherapy. (NCT01706939)
Timeframe: at 5 years

Interventionbiomarkers (Number)
Reduced Dose Radiation0
Standard Dose Radiation0

Change in MD Anderson Dysphagia Inventory (MDADI) From Baseline

MDADI is a questionnaire of 20 questions and contains a global subscale, and three other categories of questions (emotional, functional, and physical). The scores are summed and a mean score is calculated. This mean score was multiplied by 20 to obtain a score, with a range of 0 (extremely low functioning) to 100 (high functioning). Thus, a higher MDADI score represented better day-to-day functioning and better QOL. (NCT01706939)
Timeframe: Baseline and 5 years

Interventionscore on a scale (Mean)
Reduced Dose Radiation-8.12
Standard Dose Radiation-8.93

Change in Xerostomia Questionnaire (XQ)

XQ is a nine questions survey developed specifically for xerostomia symptoms. The scores are summed and a mean score is calculated on a scale of 0 (low xerostomia interference) to 10 (high xerostomia interference). A lower or negative score reflects a better quality of life compared to baseline. (NCT01706939)
Timeframe: Baseline and 5 years

Interventionscore on a scale (Mean)
Reduced Dose Radiation2.18
Standard Dose Radiation4.38

Number of Participants With Acute Toxicity of Chemoradiotherapy (CRT)

Number of participants with acute toxicity treated with reduced or standard dose CRT. (NCT01706939)
Timeframe: at 5 years

InterventionParticipants (Count of Participants)
Reduced Dose Radiation3
Standard Dose Radiation1

Number of Participants With Local-regional Control

Local-regional control (LRC) at 3 years in patients with advanced HPV related oropharynx cancer or unknown primary treated with reduced or standard dose radiation. (NCT01706939)
Timeframe: at 3 years

InterventionParticipants (Count of Participants)
Reduced Dose Radiation10
Standard Dose Radiation7

Number of Participants With Overall Survival at 5 Years

Overall Survival (OS) 5 years treated with reduced or standard dose CRT. (NCT01706939)
Timeframe: at 5 years

InterventionParticipants (Count of Participants)
Reduced Dose Radiation10
Standard Dose Radiation7

Change in European Organization for Research and Treatment of Cancer Questionnaire for Head and Neck (EORTC HN)

The EORTC Head and Neck module was specifically designed and validated for head and neck cancer patients. This 35-item questionnaire contains 7 symptom scales (pain, swallowing, senses, speech, social eating, social contact, and sexuality), 6 single-item scales (difficulties of teeth, mouth opening, dry mouth, sticky saliva, coughing, and feeling ill), and 5 items about the additional use of pain medicine, nutritional supplements, and feeding tube and changes in body weight. All items were transformed to scales from 0 to 100, and divided into respective sub-scores of global health (GHS), functional (FS), and symptom scale (SS). Subscales from 0-100. A high score on global health and functional scale represents a better level of functioning, whereas a high score on a symptom scale and head and neck module indicates more severe symptoms. (NCT01706939)
Timeframe: Baseline and 5 years

,
Interventionscore on a scale (Mean)
EORTC GHSEORTC FSEORTC SSEORTC HN
Reduced Dose Radiation5.955.14-3.91-2.80
Standard Dose Radiation-30.56-6.3314.978.97

Change in MD Anderson Symptom Inventory Symptom Inventory and Severity (MDASI-HN SI and SS)

"MD Anderson Symptom Inventory Symptom Inventory and Severity (MDASI-HN SI and SS) MDASI Head and Neck is a site-specific MDASI module which includes the core MDASI 13 symptom severity items (SS) and 6 symptom interference items (SI), alongside 9 items relevant to head and neck cancer. The scores are summed and a mean score is calculated on a scale of 0 (low severity or interference) to 10 (high severity or complete interference). In order to calculate the mean score, a majority of the subscale's items must have been completed.~A lower or negative score reflects a better quality of life compared to baseline." (NCT01706939)
Timeframe: Baseline and 5 years

,
Interventionscore on a scale (Mean)
MDASI-HN SIMDASI-HN SS
Reduced Dose Radiation0.640.52
Standard Dose Radiation1.561.48

Number of Participants With Progression Free Survival (PFS)

Progression free survival (PFS) at 5 years in patients with advanced HPV related oropharynx cancer, nasopharynx cancer or unknown primary treated with reduced or standard dose radiation. (NCT01706939)
Timeframe: at 3 and 5 years

,
InterventionParticipants (Count of Participants)
at 3 yearsat 5 years
Reduced Dose Radiation1010
Standard Dose Radiation77

Cumulative Incidence of grade3+ Bowel Perforation, Grade 3+ Bleeding (Ocurring Withing 1 Years) and grade4+ Nonhematologic Acute Adverse Events (Limited to Within 90 Days of Treatment Start)

(NCT00685763)
Timeframe: 1 year following the completion of radiation therapy

Interventionparticipants (Number)
Proton Radiation and Chemotherapy0

Reviews

7 reviews available for fluorouracil and Injuries, Radiation

ArticleYear
Combination of chemotherapy and radiotherapy: A thirty years evolution.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2019, Volume: 23, Issue:6-7

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cetuximab; Chemoradiotherapy;

2019
[Brachytherapy for oesophageal cancer].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2013, Volume: 17, Issue:2

    Topics: Antimetabolites, Antineoplastic; Brachytherapy; Chemoradiotherapy; Clinical Trials, Phase II as Topi

2013
Concurrent chemoradiotherapy was associated with a higher severe late toxicity rate in nasopharyngeal carcinoma patients compared with radiotherapy alone: a meta-analysis based on randomized controlled trials.
    Radiation oncology (London, England), 2015, Mar-26, Volume: 10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemoradiotherapy; Cisplatin; Confidence

2015
Does radiation prevent 5-fluorouracil-induced colitis in the early phase of radiochemotherapy? A case report and literature review.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2007, Volume: 183, Issue:8

    Topics: Adult; Antineoplastic Agents; Colitis; Fluorouracil; Humans; Male; Radiation Injuries; Radiotherapy,

2007
Alleviation of cytotoxic therapy-induced normal tissue damage.
    Seminars in oncology, 1995, Volume: 22, Issue:2 Suppl 3

    Topics: Chlorhexidine; Clinical Trials as Topic; Cryotherapy; Dermatitis; Esophagitis; Eye Diseases; Fluorou

1995
Retropharyngeal abscess after radiation therapy and cis-platinum, 5-fluorouracil treatment for nasopharyngeal carcinoma with collagen disease: report of two patients and a review of the literature.
    Japanese journal of clinical oncology, 1996, Volume: 26, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Collagen Diseas

1996
Drug reactions. XXIV. Cutaneous reactions to cytostatic agents.
    The British journal of dermatology, 1974, Volume: 90, Issue:2

    Topics: Alopecia; Aminopterin; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Busulfan; Chlor

1974

Trials

54 trials available for fluorouracil and Injuries, Radiation

ArticleYear
Effect of interval between preoperative radiotherapy and surgery on clinical outcome and radiation proctitis in rectal cancer from FOWARC trial.
    Cancer medicine, 2020, Volume: 9, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Cohort Stu

2020
Hypofractionated Radiation Therapy for Unresectable/Locally Recurrent Intrahepatic Cholangiocarcinoma.
    Annals of surgical oncology, 2020, Volume: 27, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Bile Duct Neoplasms; Cholangiocarcinoma; Combined Modality Therapy;

2020
Dosimetric parameters predictive of acute gastrointestinal toxicity in patients with anal carcinoma treated with concurrent chemotherapy and intensity-modulated radiation therapy.
    Oncology, 2013, Volume: 85, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Chemoradiotherapy; Cisplatin;

2013
Randomized noninferiority trial of reduced high-dose volume versus standard volume radiation therapy for muscle-invasive bladder cancer: results of the BC2001 trial (CRUK/01/004).
    International journal of radiation oncology, biology, physics, 2013, Oct-01, Volume: 87, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemo

2013
Image-guided intensity-modulated radiotherapy for patients with locally advanced gastric cancer: a clinical feasibility study.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2014, Volume: 17, Issue:3

    Topics: Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Feasibility Studies; Female; Fluoroura

2014
Phase I study of neoadjuvant accelerated short course radiation therapy with photons and capecitabine for resectable pancreatic cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 110, Issue:1

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy; Deoxycytidin

2014
Concurrent hyperfractionated accelerated radiotherapy with 5-FU and once weekly cisplatin in locally advanced head and neck cancer. The 10-year results of a prospective phase II trial.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2014, Volume: 190, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiothe

2014
[Immediate results of combined therapy for local recurrences of rectal cancer].
    Voprosy onkologii, 2015, Volume: 61, Issue:1

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Ch

2015
Treatment results of alternating chemoradiotherapy with early assessment for advanced laryngeal cancer: A multi-institutional phase II study.
    Auris, nasus, larynx, 2017, Volume: 44, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; C

2017
A Phase 1 Study of Stereotactic Body Radiation Therapy Dose Escalation for Borderline Resectable Pancreatic Cancer After Modified FOLFIRINOX (NCT01446458).
    International journal of radiation oncology, biology, physics, 2016, 10-01, Volume: 96, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy; Dose Fraction

2016
A Phase 1 Study of Stereotactic Body Radiation Therapy Dose Escalation for Borderline Resectable Pancreatic Cancer After Modified FOLFIRINOX (NCT01446458).
    International journal of radiation oncology, biology, physics, 2016, 10-01, Volume: 96, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy; Dose Fraction

2016
A Phase 1 Study of Stereotactic Body Radiation Therapy Dose Escalation for Borderline Resectable Pancreatic Cancer After Modified FOLFIRINOX (NCT01446458).
    International journal of radiation oncology, biology, physics, 2016, 10-01, Volume: 96, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy; Dose Fraction

2016
A Phase 1 Study of Stereotactic Body Radiation Therapy Dose Escalation for Borderline Resectable Pancreatic Cancer After Modified FOLFIRINOX (NCT01446458).
    International journal of radiation oncology, biology, physics, 2016, 10-01, Volume: 96, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemoradiotherapy; Dose Fraction

2016
Impact of Preoperative Radiotherapy on Anastomotic Leakage and Stenosis After Rectal Cancer Resection: Post Hoc Analysis of a Randomized Controlled Trial.
    Diseases of the colon and rectum, 2016, Volume: 59, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Anastomosis, Surgical; Anastomotic Leak; Antineoplastic Agents; Chemora

2016
Impact of Preoperative Radiotherapy on Anastomotic Leakage and Stenosis After Rectal Cancer Resection: Post Hoc Analysis of a Randomized Controlled Trial.
    Diseases of the colon and rectum, 2016, Volume: 59, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Anastomosis, Surgical; Anastomotic Leak; Antineoplastic Agents; Chemora

2016
Impact of Preoperative Radiotherapy on Anastomotic Leakage and Stenosis After Rectal Cancer Resection: Post Hoc Analysis of a Randomized Controlled Trial.
    Diseases of the colon and rectum, 2016, Volume: 59, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Anastomosis, Surgical; Anastomotic Leak; Antineoplastic Agents; Chemora

2016
Impact of Preoperative Radiotherapy on Anastomotic Leakage and Stenosis After Rectal Cancer Resection: Post Hoc Analysis of a Randomized Controlled Trial.
    Diseases of the colon and rectum, 2016, Volume: 59, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Anastomosis, Surgical; Anastomotic Leak; Antineoplastic Agents; Chemora

2016
[Neoadjuvant short-term radiotherapy followed by FOLFOX chemotherapy : No standard treatment for rectal cancer].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2016, Volume: 192, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Female; Fluorouracil; Guide

2016
[Inclusion of oxaliplatin in the multimodal treatment of locally advanced rectal cancer].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2017, Volume: 193, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherap

2017
Major late toxicities after conformal radiotherapy for nasopharyngeal carcinoma-patient- and treatment-related risk factors.
    International journal of radiation oncology, biology, physics, 2009, Mar-15, Volume: 73, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemothe

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Intensity-modulated radiation therapy with or without chemotherapy for nasopharyngeal carcinoma: radiation therapy oncology group phase II trial 0225.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Aug-01, Volume: 27, Issue:22

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modalit

2009
Phase I study of concurrent selective lymph node late course accelerated hyper-fractionated radiotherapy and Capecitabine, Cisplatin for locally advanced esophageal squamous cell carcinoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 93, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Squamous Cell;

2009
A phase I study of capecitabine, irinotecan, celecoxib, and radiation as neoadjuvant therapy of patients with locally advanced rectal cancer.
    American journal of clinical oncology, 2010, Volume: 33, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitab

2010
[Extended preoperative course of radiotherapy as component of combined and complex treatment of locally-advanced ampular rectal cancer].
    Voprosy onkologii, 2010, Volume: 56, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Fluoro

2010
Comparison of the micronucleus and chromosome aberration techniques for the documentation of cytogenetic damage in radiochemotherapy-treated patients with rectal cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Combined Modality Ther

2011
Phenylbutyrate mouthwash mitigates oral mucositis during radiotherapy or chemoradiotherapy in patients with head-and-neck cancer.
    International journal of radiation oncology, biology, physics, 2012, Mar-15, Volume: 82, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cisplatin; Double-Blind Method; E

2012
Acute toxicity of radiochemotherapy in rectal cancer patients: a risk particularly for carriers of the TGFB1 Pro25 variant.
    International journal of radiation oncology, biology, physics, 2012, May-01, Volume: 83, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; C

2012
Phase II study of preoperative helical tomotherapy with a simultaneous integrated boost for rectal cancer.
    International journal of radiation oncology, biology, physics, 2012, May-01, Volume: 83, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Chemoradiotherapy; Disease-Free Survival; Dose Fract

2012
Alternating chemoradiotherapy in patients with nasopharyngeal cancer: prognostic factors and proposal for individualization of therapy.
    Journal of radiation research, 2013, Volume: 54, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; C

2013
RTOG 0529: a phase 2 evaluation of dose-painted intensity modulated radiation therapy in combination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal.
    International journal of radiation oncology, biology, physics, 2013, May-01, Volume: 86, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Analysis of Variance; Antineoplastic Combined Chemothera

2013
Early results from a phase I/II radiation dose-escalation study with concurrent amifostine and infusional 5-fluorouracil chemotherapy for preoperative treatment of unresectable or locally recurrent rectal carcinoma.
    Seminars in oncology, 2002, Volume: 29, Issue:6 Suppl 19

    Topics: Adenocarcinoma; Amifostine; Antimetabolites, Antineoplastic; Combined Modality Therapy; Cytoprotecti

2002
Concurrent mitomycin C, 5-fluorouracil, and radiotherapy in the treatment of locally advanced carcinoma of the cervix: a randomized trial.
    International journal of radiation oncology, biology, physics, 2003, Apr-01, Volume: 55, Issue:5

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; B

2003
Selenium in the treatment of radiation-associated secondary lymphedema.
    International journal of radiation oncology, biology, physics, 2003, May-01, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ci

2003
Contribution of conformal therapy in the treatment of anal canal carcinoma with combined chemotherapy and radiotherapy: results of a phase II study.
    International journal of radiation oncology, biology, physics, 2003, Jul-01, Volume: 56, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2003
Results of a phase I study to determine the maximum tolerated dose of capecitabine when given concurrently with radical radiotherapy in the treatment of squamous cell carcinoma of the head and neck.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2004, Volume: 71, Issue:1

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Capecitabine; Carcinoma, Squamous Cell; Combi

2004
Intensity-modulated radiotherapy in treatment of pancreatic and bile duct malignancies: toxicity and clinical outcome.
    International journal of radiation oncology, biology, physics, 2004, Jun-01, Volume: 59, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antimetabolites, Antineoplasti

2004
[Preoperative concurrent radiation therapy and chemotherapy for operable bulky carcinomas of uterine cervix stages IB2, IIA, and IIB with proximal parametrial invasion].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2004, Volume: 8, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinoma; Cisplatin; Di

2004
Phase II trial of hyperfractionated accelerated split-course radiochemotherapy with 5-FU and Cis-DDP in advanced head and neck cancer: results and toxicity.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2004, Volume: 180, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; D

2004
Neoadjuvant accelerated chemotherapy followed by hyperfractionated radiation therapy in patients with operable, locally advanced head and neck carcinoma.
    Oral oncology, 2005, Volume: 41, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy,

2005
Induction chemotherapy followed by concurrent chemoradiation in advanced squamous cell carcinoma of the head and neck: final results from a phase II study with docetaxel, cisplatin and 5-fluorouracil with a four-year follow-up.
    Oral oncology, 2006, Volume: 42, Issue:7

    Topics: Adult; Age Distribution; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous C

2006
[Simultaneous radiochemotherapy and endoluminal HDR brachytherapy in esophageal cancer].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2007, Volume: 183, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Cispl

2007
Phase II study of consolidation chemotherapy after concurrent chemoradiation in cervical cancer: preliminary results.
    International journal of radiation oncology, biology, physics, 2007, Jul-01, Volume: 68, Issue:3

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cispla

2007
Esophageal cancer. A prospective phase II study of concomitant-boost external-beam chemoradiation with a top-up endoluminal boost.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2008, Volume: 184, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brac

2008
Concurrent cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy and radiotherapy for early breast carcinoma.
    International journal of radiation oncology, biology, physics, 2008, Jul-01, Volume: 71, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Comorbidity; Cyclopho

2008
Evaluation of planned treatment breaks during radiation therapy for anal cancer: update of RTOG 92-08.
    International journal of radiation oncology, biology, physics, 2008, Sep-01, Volume: 72, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Colo

2008
Dose and volume effects on fibrosis after breast conservation therapy.
    International journal of radiation oncology, biology, physics, 1994, Dec-01, Volume: 30, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Breast Neoplasms; Cispla

1994
Concurrent chemotherapy and radiation therapy for locally advanced carcinoma of the esophagus.
    Japanese journal of clinical oncology, 1995, Volume: 25, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Esophage

1995
Combined chemoradiotherapy vs. radiotherapy alone for early stage squamous cell carcinoma of the esophagus: a study of the Eastern Cooperative Oncology Group.
    International journal of radiation oncology, biology, physics, 1998, Sep-01, Volume: 42, Issue:2

    Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Comb

1998
Phase I/II trial of radiation with chemotherapy "boost" for advanced squamous cell carcinomas of the head and neck: toxicities and responses.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:8

    Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous

1999
Myeloprotective effect of a non-toxic indigenous preparation Rasayana in cancer patients receiving chemotherapy and radiation therapy. A pilot study.
    Journal of experimental & clinical cancer research : CR, 1999, Volume: 18, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Bone Marrow; Chemotherapy, Adjuvant; C

1999
Intermittent use of amifostine during postoperative radiochemotherapy and acute toxicity in rectal cancer patients.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2000, Volume: 176, Issue:9

    Topics: Amifostine; Chemotherapy, Adjuvant; Combined Modality Therapy; Dose Fractionation, Radiation; Fluoro

2000
Preoperative hyperfractionated radiotherapy with concurrent chemotherapy in resectable esophageal cancer.
    International journal of radiation oncology, biology, physics, 2001, May-01, Volume: 50, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Combined Modality Therapy; Disease-

2001
A phase I/II trial of three-dimensionally planned concurrent boost radiotherapy and protracted venous infusion of 5-FU chemotherapy for locally advanced rectal carcinoma.
    International journal of radiation oncology, biology, physics, 2001, Aug-01, Volume: 50, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Colectomy; Combined

2001
Phase II clinical trial of preoperative combined chemoradiation for T3 and T4 resectable rectal cancer: preliminary results.
    Diseases of the colon and rectum, 2001, Volume: 44, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Combined Modality Therapy; Dose Fracti

2001
Neoadjuvant chemotherapy plus conventional radiotherapy or accelerated hyperfractionation in stage III and IV nasopharyngeal carcinoma--a phase II study.
    Acta oncologica (Stockholm, Sweden), 2001, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Carcinoma, Squam

2001
Concurrent cisplatin and 5-fluorouracil chemotherapy and radiation therapy for advanced-stage squamous carcinoma of the vulva.
    Gynecologic oncology, 1991, Volume: 42, Issue:3

    Topics: Aged; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Drug Therapy, Combination; Fem

1991
Concomitant 5-fluorouracil infusion and high-dose radiation for stage III non-small cell lung cancer.
    Cancer, 1989, Sep-01, Volume: 64, Issue:5

    Topics: Aged; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Combined Modality Therapy; Esophagit

1989
Radiation therapy combined with Adriamycin or 5-fluorouracil for the treatment of locally unresectable pancreatic carcinoma. Gastrointestinal Tumor Study Group.
    Cancer, 1985, Dec-01, Volume: 56, Issue:11

    Topics: Adenocarcinoma; Combined Modality Therapy; Doxorubicin; Female; Fluorouracil; Humans; Male; Middle A

1985
[Side effects of adjuvant therapies of breast cancer: their significance for the patient].
    Wiener klinische Wochenschrift, 1989, Feb-17, Volume: 101, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality The

1989
Combined 5-fluorouracil and radiation therapy following resection of locally advanced gastric carcinoma: a 5-years follow-up.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 110

    Topics: Adult; Aged; Clinical Trials as Topic; Combined Modality Therapy; Female; Fluorouracil; Follow-Up St

1988

Other Studies

114 other studies available for fluorouracil and Injuries, Radiation

ArticleYear
Improved treatment outcome and lower skin toxicity with intensity-modulated radiotherapy vs. 3D conventional radiotherapy in anal cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2020, Volume: 196, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anus Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; F

2020
Feasibility of relatively low neoadjuvant radiation doses for locally advanced rectal cancer: A propensity score-matched analysis.
    Cancer reports (Hoboken, N.J.), 2019, Volume: 2, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy, Adjuvant; Disease-Free Surv

2019
Anal Squamous Cell Carcinoma in Ulcerative Colitis: Can Pouches Withstand Traditional Treatment Protocols?
    Diseases of the colon and rectum, 2021, 09-01, Volume: 64, Issue:9

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cel

2021
Stereotactic body radiation vs. intensity-modulated radiation for unresectable pancreatic cancer.
    Acta oncologica (Stockholm, Sweden), 2017, Volume: 56, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anemia; Antineoplastic Combined Chemotherapy Protoco

2017
The Prognostic Nutrition Index Predicts the Development of Hematological Toxicities in and the Prognosis of Esophageal Cancer Patients Treated with Cisplatin Plus 5-Fluorouracil Chemotherapy.
    Nutrition and cancer, 2018, Volume: 70, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; C

2018
Intensity-modulated Radiotherapy for Anal Cancer: Dose-Volume Relationship of Acute Gastrointestinal Toxicity and Disease Outcomes.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2018, Volume: 30, Issue:10

    Topics: Abdominal Cavity; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; An

2018
Radiation-induced nasopharyngeal ulcers after intensity modulated radiotherapy in primary nasopharyngeal carcinoma patients: A dose-volume-outcome analysis.
    Oral oncology, 2018, Volume: 84

    Topics: Adult; Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Cisplatin; Combined Modality Therapy; De

2018
Temporal lobe injury patterns following intensity modulated radiotherapy in a large cohort of nasopharyngeal carcinoma patients.
    Oral oncology, 2018, Volume: 85

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Edema; Cisplatin; Docetaxel; Female; Flu

2018
Chemoradiation in female patients with anal cancer: Patient-reported outcome of acute and chronic side effects.
    Tumori, 2019, Volume: 105, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2019
Effect of 5-fluorouracil on cellular response to proton beam in esophageal cancer cell lines according to the position of spread-out Bragg peak.
    Acta oncologica (Stockholm, Sweden), 2019, Volume: 58, Issue:4

    Topics: Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Survival; Dose-Response Relationship

2019
Tumor-Infiltrating T Cell Receptor-Beta Repertoires are Linked to the Risk of Late Chemoradiation-Induced Temporal Lobe Necrosis in Locally Advanced Nasopharyngeal Carcinoma.
    International journal of radiation oncology, biology, physics, 2019, 05-01, Volume: 104, Issue:1

    Topics: Analysis of Variance; Antineoplastic Agents; Chemoradiotherapy; Cisplatin; Fluorouracil; Humans; Leu

2019
The heart's exposure to radiation increases the risk of cardiac toxicity after chemoradiotherapy for superficial esophageal cancer: a retrospective cohort study.
    BMC cancer, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Atrial Fibrillation; Cardiotoxicity; Chemoradi

2019
Gastric mucosal injury and hemorrhage after definitive chemoradiotherapy for locally advanced esophageal cancer.
    Esophagus : official journal of the Japan Esophageal Society, 2019, Volume: 16, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous

2019
Hypovolemic shock after pelvic radiotherapy. A rare combination leading to a devastating complication.
    Annali italiani di chirurgia, 2019, Jun-26, Volume: 8

    Topics: Aged; Anaphylaxis; Anus Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Chemoradiotherapy; Colon, Si

2019
Proton therapy with concomitant capecitabine for pancreatic and ampullary cancers is associated with a low incidence of gastrointestinal toxicity.
    Acta oncologica (Stockholm, Sweden), 2013, Volume: 52, Issue:3

    Topics: Adenocarcinoma; Administration, Oral; Aged; Ampulla of Vater; Capecitabine; Chemoradiotherapy; Commo

2013
Ring-enhancing lesion associated with radiation-induced liver disease.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, May-10, Volume: 31, Issue:14

    Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chem

2013
Predictive factors for early and late local toxicities in anal cancer treated by radiotherapy in combination with or without chemotherapy.
    Diseases of the colon and rectum, 2013, Volume: 56, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Brac

2013
Intensity-modulated Radiation Therapy for Anal Cancer: Results From a Multi-Institutional Retrospective Cohort Study.
    American journal of clinical oncology, 2016, Volume: 39, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Cape

2016
Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration.
    Genes & development, 2014, May-01, Volume: 28, Issue:9

    Topics: Animals; Antineoplastic Agents; beta Catenin; Bone Marrow; DNA Breaks, Double-Stranded; Fluorouracil

2014
Late complications after proctectomy in rectal cancer patients who underwent radiotherapy.
    World journal of surgery, 2014, Volume: 38, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Antineoplastic Agents; Case-C

2014
IMRT limits nephrotoxicity after chemoradiotherapy for gastric cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2014, Volume: 112, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemoradiotherapy; Cisplatin; Deoxycyt

2014
Radiation recall gastritis secondary to erlotinib in a patient with pancreatic cancer.
    Anticancer research, 2014, Volume: 34, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Capecitabine; Combined Modality The

2014
Efficacy and safety of neoadjuvant intensity-modulated radiotherapy with concurrent capecitabine for locally advanced rectal cancer.
    Diseases of the colon and rectum, 2015, Volume: 58, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemo

2015
[Management of locally advanced anal canal carcinoma with modulated arctherapy and concurrent chemotherapy].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2015, Volume: 19, Issue:2

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carcinoma, Squamous Cell

2015
Potential Role of Single Nucleotide Polymorphisms of XRCC1, XRCC3, and RAD51 in Predicting Acute Toxicity in Rectal Cancer Patients Treated With Preoperative Radiochemotherapy.
    American journal of clinical oncology, 2017, Volume: 40, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Chemoradiothera

2017
Images in clinical medicine. Radiation recall and woody fibrosis.
    The New England journal of medicine, 2015, May-14, Volume: 372, Issue:20

    Topics: Aged; Antimetabolites, Antineoplastic; Breast Neoplasms; Female; Fluorouracil; Humans; Lumbar Verteb

2015
Chemoradiation for High-grade Neuroendocrine Carcinoma of the Rectum and Anal Canal.
    American journal of clinical oncology, 2017, Volume: 40, Issue:6

    Topics: Adult; Aged; Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Camptotheci

2017
Clinical Study on Lobaplatin Combined with 5-Fu and Concurrent Radiotherapy in Treating Patients with Inoperable Esophageal Cancer.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:15

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Carcinoma, Squamous Cell

2015
Radiation-induced injury of the exocrine pancreas after chemoradiotherapy for gastric cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2016, Volume: 118, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Exocrine Pancreatic

2016
[Clinical analysis of multimodal treatment for orbital organ preservation in T4b squamous cell carcinoma of nasal cavity and paranasal sinuses].
    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery, 2016, Jul-07, Volume: 51, Issue:7

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cis

2016
Lumbar-sacral bone marrow dose modeling for acute hematological toxicity in anal cancer patients treated with concurrent chemo-radiation.
    Medical oncology (Northwood, London, England), 2016, Volume: 33, Issue:12

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Bone Marrow; Chemoradio

2016
Fertility preservation for young women with rectal cancer--a combined approach from one referral center.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2009, Volume: 13, Issue:6

    Topics: Adult; Antimetabolites, Antineoplastic; Cryopreservation; Female; Fluorouracil; Humans; Infertility,

2009
Radiotherapy for epidermoid carcinoma of the anus: thirty years' experience.
    International journal of radiation oncology, biology, physics, 2009, Oct-01, Volume: 75, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols

2009
Late toxicity after definitive concurrent chemoradiotherapy for thoracic esophageal carcinoma.
    International journal of radiation oncology, biology, physics, 2009, Sep-01, Volume: 75, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squ

2009
Combined adjuvant radiochemotherapy with IMRT/XELOX improves outcome with low renal toxicity in gastric cancer.
    International journal of radiation oncology, biology, physics, 2009, Nov-15, Volume: 75, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Capecitabine; Chemotherapy,

2009
High-dose rate brachytherapy using inverse planning simulated annealing for locoregionally advanced cervical cancer: a clinical report with 2-year follow-up.
    International journal of radiation oncology, biology, physics, 2009, Dec-01, Volume: 75, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Agents; Brachytherapy; Carcinoma, Squamous Cell; Cisplatin; Female; F

2009
[Risk of cardiotoxicity of combination treatment radiotherapy and chemotherapy of locally advanced breast carcinoma stage III].
    Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2009, Volume: 22, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Brea

2009
Predicting grade 3 acute diarrhea during radiation therapy for rectal cancer using a cutoff-dose logistic regression normal tissue complication probability model.
    International journal of radiation oncology, biology, physics, 2010, May-01, Volume: 77, Issue:1

    Topics: Antimetabolites, Antineoplastic; Diarrhea; Dose-Response Relationship, Radiation; Fluorouracil; Huma

2010
Hyperfractionated accelerated radiotherapy for rectal cancer in patients with prior pelvic irradiation.
    International journal of radiation oncology, biology, physics, 2010, May-01, Volume: 77, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Capecitabine; Combined Modality Therapy; Deox

2010
Radiochemotherapy including cisplatin alone versus cisplatin + 5-fluorouracil for locally advanced unresectable stage IV squamous cell carcinoma of the head and neck.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2009, Volume: 185, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Ci

2009
High-grade acute organ toxicity during preoperative radiochemotherapy as positive predictor for complete histopathologic tumor regression in multimodal treatment of locally advanced rectal cancer.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2010, Volume: 186, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherap

2010
Renal atrophy secondary to chemoradiotherapy of abdominal malignancies.
    International journal of radiation oncology, biology, physics, 2010, Oct-01, Volume: 78, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; At

2010
Comparison of four cisplatin-based radiochemotherapy regimens for nonmetastatic stage III/IV squamous cell carcinoma of the head and neck.
    International journal of radiation oncology, biology, physics, 2011, Jul-15, Volume: 80, Issue:4

    Topics: Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisp

2011
Validation of the Total Dysphagia Risk Score (TDRS) as a predictive measure for acute swallowing dysfunction induced by chemoradiotherapy for head and neck cancers.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2010, Volume: 97, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chi-Squa

2010
Favorable outcome with bevacizumab after poor outcome with steroids in a patient with temporal lobe and brainstem radiation necrosis.
    Journal of neurology, 2011, Volume: 258, Issue:2

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab

2011
Gastroduodenal complications after concurrent chemoradiation therapy in patients with hepatocellular carcinoma: endoscopic findings and risk factors.
    International journal of radiation oncology, biology, physics, 2011, Dec-01, Volume: 81, Issue:5

    Topics: Adult; Antimetabolites, Antineoplastic; Carcinoma, Hepatocellular; Chemoradiotherapy; Duodenal Ulcer

2011
[Early-onset radiation complications and tissue damage in the treatment of head and neck tumors].
    Voprosy onkologii, 2010, Volume: 56, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Chemotherapy, Adjuvant;

2010
Factors associated with pharyngoesophageal stricture in patients treated with concurrent chemotherapy and radiation therapy for oropharyngeal squamous cell carcinoma.
    Head & neck, 2011, Volume: 33, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

2011
Factors associated with pharyngoesophageal stricture in patients treated with concurrent chemotherapy and radiation therapy for oropharyngeal squamous cell carcinoma.
    Head & neck, 2011, Volume: 33, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

2011
Factors associated with pharyngoesophageal stricture in patients treated with concurrent chemotherapy and radiation therapy for oropharyngeal squamous cell carcinoma.
    Head & neck, 2011, Volume: 33, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

2011
Factors associated with pharyngoesophageal stricture in patients treated with concurrent chemotherapy and radiation therapy for oropharyngeal squamous cell carcinoma.
    Head & neck, 2011, Volume: 33, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modali

2011
Exclusive alternating chemotherapy and radiotherapy in nonmetastatic inflammatory breast cancer: 20 years of follow-up.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachial Plexus Neuropathies; Carcinoma

2012
Quality of life outcomes in patients with anal cancer after combined radiochemotherapy.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011, Volume: 187, Issue:3

    Topics: Activities of Daily Living; Adult; Aged; Aged, 80 and over; Anus Neoplasms; Chemotherapy, Adjuvant;

2011
Primary lung cancer surgery after curative chemoradiotherapy for esophageal cancer patients.
    Interactive cardiovascular and thoracic surgery, 2011, Volume: 12, Issue:6

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; C

2011
[Analysis of the factors related to esophageal injuries in radiotherapy of esophageal cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2011, Volume: 33, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Th

2011
[Neoadjuvant radiochemotherapy for rectal cancer].
    MMW Fortschritte der Medizin, 2011, Sep-01, Volume: 153, Issue:35

    Topics: Antimetabolites, Antineoplastic; Chemotherapy, Adjuvant; Combined Modality Therapy; Fluorouracil; Hu

2011
Anastomotic complications after Ivor Lewis esophagectomy in patients treated with neoadjuvant chemoradiation are related to radiation dose to the gastric fundus.
    International journal of radiation oncology, biology, physics, 2012, Mar-01, Volume: 82, Issue:3

    Topics: Adult; Aged; Anastomosis, Surgical; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherap

2012
Radiotherapy-induced pemphigus vulgaris with autoantibodies targeting a 110 kDa epidermal antigen.
    International journal of dermatology, 2011, Volume: 50, Issue:12

    Topics: Acantholysis; Adrenal Cortex Hormones; Antigens; Antineoplastic Agents; Autoantibodies; Carcinoma; C

2011
Low-dose-rate californium-252 neutron intracavitary afterloading radiotherapy combined with conformal radiotherapy for treatment of cervical cancer.
    International journal of radiation oncology, biology, physics, 2012, Jul-01, Volume: 83, Issue:3

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brac

2012
Comparing cystatin C changes as a measure of renal function before and after radiotherapy in patients with stomach cancer.
    Acta medica Iranica, 2012, Volume: 50, Issue:1

    Topics: Aged; Antimetabolites, Antineoplastic; Biomarkers; Blood Urea Nitrogen; Capecitabine; Chemoradiother

2012
Comparison of acute toxicities in two primary chemoradiation regimens in the treatment of advanced head and neck squamous cell carcinoma.
    Annals of surgical oncology, 2012, Volume: 19, Issue:6

    Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell

2012
Development of a standardized method for contouring the lumbosacral plexus: a preliminary dosimetric analysis of this organ at risk among 15 patients treated with intensity-modulated radiotherapy for lower gastrointestinal cancers and the incidence of rad
    International journal of radiation oncology, biology, physics, 2012, Oct-01, Volume: 84, Issue:2

    Topics: Anatomic Landmarks; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Fluorouracil; Hu

2012
Small bowel dose parameters predicting grade ≥ 3 acute toxicity in rectal cancer patients treated with neoadjuvant chemoradiation: an independent validation study comparing peritoneal space versus small bowel loop contouring techniques.
    International journal of radiation oncology, biology, physics, 2013, Apr-01, Volume: 85, Issue:5

    Topics: Antimetabolites, Antineoplastic; Chemoradiotherapy, Adjuvant; Female; Fluorouracil; Humans; Intestin

2013
[Hypersensitivity to radiation therapy in a patient with tuberous sclerosis: biological considerations about a clinical case].
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2013, Volume: 17, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemoradiotherapy; Cisplat

2013
Ten-year results of chemoradiation for anal cancer: focus on late morbidity.
    International journal of radiation oncology, biology, physics, 1996, Jan-01, Volume: 34, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Comb

1996
Estimating risks of radiotherapy complications as part of informed consent: the high degree of variability between radiation oncologists may be related to experience.
    International journal of radiation oncology, biology, physics, 2002, Nov-01, Volume: 54, Issue:3

    Topics: Antimetabolites, Antineoplastic; Australia; Dose-Response Relationship, Radiation; Fluorouracil; Hea

2002
Linear accelerator-based stereotactic radiosurgery for limited, locally persistent, and recurrent nasopharyngeal carcinoma: efficacy and complications.
    International journal of radiation oncology, biology, physics, 2003, May-01, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chemother

2003
The significance of cardiac doses received during chemoradiation of oesophageal and gastro-oesophageal junctional cancers.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2003, Volume: 15, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Combined Modality Thera

2003
Preclinical characterization of CG53135 (FGF-20) in radiation and concomitant chemotherapy/radiation-induced oral mucositis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Aug-15, Volume: 9, Issue:9

    Topics: Animals; Bromodeoxyuridine; Cheek; Coloring Agents; Cricetinae; Dose-Response Relationship, Drug; Fi

2003
[RESEARCH ON CERTAIN DIGESTIVE DYSKINESIAS AND FUNCTIONAL DISORDERS].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1964, May-15, Volume: 115

    Topics: Antiemetics; Apomorphine; Cobalt Isotopes; Cyclophosphamide; Digitalis Glycosides; Dyskinesias; Dysp

1964
[Radiation-induced mucositis and neutrophil granulocytes in oral mucosa].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2003, Volume: 179, Issue:10

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Combined Modality Therapy

2003
Reduction of radiochemotherapy-induced early oral mucositis by recombinant human keratinocyte growth factor (palifermin): experimental studies in mice.
    International journal of radiation oncology, biology, physics, 2005, Jul-01, Volume: 62, Issue:3

    Topics: Animals; Cisplatin; Dose Fractionation, Radiation; Drug Evaluation, Preclinical; Fibroblast Growth F

2005
Early occurrence of chylothorax related to thoracic irradiation and concomitant chemotherapy.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2005, Volume: 17, Issue:4

    Topics: Adenocarcinoma; Ampulla of Vater; Antineoplastic Combined Chemotherapy Protocols; Chylothorax; Cispl

2005
Survival impact of planned restaging and early surgical salvage following definitive chemoradiation for locally advanced squamous cell carcinomas of the oropharynx and hypopharynx.
    American journal of clinical oncology, 2005, Volume: 28, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carboplatin;

2005
Preliminary results of radiation dose escalation for locally advanced nasopharyngeal carcinoma.
    International journal of radiation oncology, biology, physics, 2006, Feb-01, Volume: 64, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Combined Modality

2006
Myelopathy after radiation therapy and chemotherapy with capecitabine and gemcitabine.
    Cancer investigation, 2005, Volume: 23, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Deoxycytidi

2005
Quantification and reduction of cardiac dose in radical radiotherapy for oesophageal cancer.
    The British journal of radiology, 2005, Volume: 78, Issue:936

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modalit

2005
Damage assessment in gastric cancer treatment with adjuvant radiochemotherapy: calculation of the NTCP's from the differential HDV of the organs at risk.
    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2006, Volume: 8, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Chemotherap

2006
[Vascular hepatic injury following neoadjuvant treatment for a cardial adenocarcinoma].
    Gastroenterologie clinique et biologique, 2006, Volume: 30, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cardia; Cisplatin; Female; Fluoroura

2006
Acute proctocolitis with commencement of neoadjuvant chemoradiation for rectal cancer.
    American journal of clinical oncology, 2006, Volume: 29, Issue:5

    Topics: Acute Disease; Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Dose Fractionation, Radiation;

2006
Regression of radiation-induced macular edema after systemic bevacizumab.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2007, Volume: 42, Issue:5

    Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetab

2007
Dose-volume relationships between enteritis and irradiated bowel volumes during 5-fluorouracil and oxaliplatin based chemoradiotherapy in locally advanced rectal cancer.
    Acta oncologica (Stockholm, Sweden), 2007, Volume: 46, Issue:7

    Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Dose Fractionation, Radiation; Dose-R

2007
Intensity-modulated radiotherapy for head and neck cancer of unknown primary: toxicity and preliminary efficacy.
    International journal of radiation oncology, biology, physics, 2008, Mar-15, Volume: 70, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcino

2008
Weekly large fraction radiotherapy and 5 fluorouracil as a palliative treatment for large bowel carcinoma: a pilot study.
    International journal of radiation oncology, biology, physics, 1982, Volume: 8, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Diarrhea; Fluorouracil; Humans; Intestinal Neoplasms; Intestine, Large;

1982
Advanced minimal residual ovarian carcinoma: abdominopelvic irradiation following combination chemotherapy.
    Obstetrics and gynecology, 1983, Volume: 61, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherap

1983
[Combination chemotherapy and radiotherapy. Differential effect, on the intestinal syndrome, of fractionated irradiation with fractionated drug administration].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1982, Volume: 176, Issue:1

    Topics: Animals; Disease Models, Animal; Drug Administration Schedule; Female; Fluorouracil; Intestinal Dise

1982
[Combination chemotherapy and radiotherapy. Differential effect, on the medullary syndrome, of fractionated irradiation with fractionated drug administration].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1982, Volume: 176, Issue:1

    Topics: Animals; Brain Diseases; Disease Models, Animal; Drug Administration Schedule; Female; Fluorouracil;

1982
Carcinoma of the hand: a 20-year experience.
    Southern medical journal, 1984, Volume: 77, Issue:8

    Topics: Adult; Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cryosurgery; Female; Fluorouracil; Fol

1984
[Retinoic acid and 5-FU mixture in the topical treatment of several skin diseases (author's transl)].
    L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma, 1980, Volume: 51, Issue:3

    Topics: Drug Combinations; Fluorouracil; Humans; Keratosis; Ointments; Radiation Injuries; Skin Diseases; Sy

1980
Protection of the gastrointestinal mucosa by elemental diets.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1980, Volume: 3, Issue:3-4

    Topics: Animals; Fluorouracil; Food, Formulated; Humans; Hypotension; Intestinal Mucosa; Radiation Injuries;

1980
[Therapy of anal cancer].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1994, Volume: 65, Issue:4

    Topics: Anal Canal; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combined Modality Therap

1994
Combined chemotherapy and radiation for bulky stages I-II cervical cancer: comparison of concurrent and sequential regimens.
    Gynecologic oncology, 1993, Volume: 50, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Chemotherapy, A

1993
High complete response rate of concomitant chemoradiotherapy for locally advanced squamous cell carcinoma of the uterine cervix.
    Gynecologic oncology, 1996, Volume: 61, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Brachytherapy; Carcinoma, Sq

1996
Role of mitomycin C in the development of late bowel toxicity following chemoradiation for locally advanced carcinoma of the cervix.
    International journal of radiation oncology, biology, physics, 1997, Jul-15, Volume: 38, Issue:5

    Topics: Adenocarcinoma; Adenocarcinoma, Clear Cell; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplas

1997
Mature results of a pilot study of pelvic radiotherapy with concurrent continuous infusion intra-arterial 5-FU for stage IIIB-IVA squamous cell carcinoma of the cervix.
    International journal of radiation oncology, biology, physics, 1999, Aug-01, Volume: 45, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combined Modality Therapy; F

1999
Locoregional irradiation for inflammatory breast cancer: effectiveness of dose escalation in decreasing recurrence.
    International journal of radiation oncology, biology, physics, 2000, Jul-15, Volume: 47, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvan

2000
High-dose-rate intraoperative brachytherapy for recurrent colorectal cancer.
    International journal of radiation oncology, biology, physics, 2000, Aug-01, Volume: 48, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brachytherapy; Colonic Neopla

2000
Absorbable mesh sling prevents radiation-induced bowel injury during "sandwich" chemoradiation for rectal cancer.
    Archives of surgery (Chicago, Ill. : 1960), 2000, Volume: 135, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Case-Control Studies; Chemotherapy, Adjuvant; Dose-Response Relationshi

2000
Long-term follow-up of RTOG 92-10: cervical cancer with positive para-aortic lymph nodes.
    International journal of radiation oncology, biology, physics, 2001, Nov-15, Volume: 51, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinom

2001
Long-term follow-up of RTOG 92-10: cervical cancer with positive para-aortic lymph nodes.
    International journal of radiation oncology, biology, physics, 2001, Nov-15, Volume: 51, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinom

2001
Long-term follow-up of RTOG 92-10: cervical cancer with positive para-aortic lymph nodes.
    International journal of radiation oncology, biology, physics, 2001, Nov-15, Volume: 51, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinom

2001
Long-term follow-up of RTOG 92-10: cervical cancer with positive para-aortic lymph nodes.
    International journal of radiation oncology, biology, physics, 2001, Nov-15, Volume: 51, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinom

2001
Long-term follow-up of RTOG 92-10: cervical cancer with positive para-aortic lymph nodes.
    International journal of radiation oncology, biology, physics, 2001, Nov-15, Volume: 51, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinom

2001
Long-term follow-up of RTOG 92-10: cervical cancer with positive para-aortic lymph nodes.
    International journal of radiation oncology, biology, physics, 2001, Nov-15, Volume: 51, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinom

2001
Long-term follow-up of RTOG 92-10: cervical cancer with positive para-aortic lymph nodes.
    International journal of radiation oncology, biology, physics, 2001, Nov-15, Volume: 51, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinom

2001
Long-term follow-up of RTOG 92-10: cervical cancer with positive para-aortic lymph nodes.
    International journal of radiation oncology, biology, physics, 2001, Nov-15, Volume: 51, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinom

2001
Long-term follow-up of RTOG 92-10: cervical cancer with positive para-aortic lymph nodes.
    International journal of radiation oncology, biology, physics, 2001, Nov-15, Volume: 51, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brachytherapy; Carcinom

2001
Advanced head and neck cancer: long-term results of chemo-radiotherapy, complications and induction of second malignancies.
    Onkologie, 2001, Volume: 24, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cobalt Radioisotopes; Combined Moda

2001
Radiochemotherapy for anal carcinoma - effectivity and late toxicity.
    Onkologie, 2002, Volume: 25, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Carc

2002
Rationale for a phase I/II radiation dose-escalation study with concurrent amifostine (Ethyol) and infusional 5-FU chemotherapy for preoperative treatment of unresectable or locally recurrent rectal carcinoma.
    Seminars in radiation oncology, 2002, Volume: 12, Issue:1 Suppl 1

    Topics: Adenocarcinoma; Amifostine; Antimetabolites, Antineoplastic; Clinical Trials, Phase I as Topic; Clin

2002
Trimodal combination therapy for maxillary sinus carcinoma.
    International journal of radiation oncology, biology, physics, 2002, Jul-01, Volume: 53, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Combin

2002
Combined modality therapy of hepatic metastasis. Northern California Oncology Group Pilot Study.
    Cancer, 1979, Volume: 44, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents; Bone Marrow; Doxorubicin; Drug Evaluation; Drug Therapy, Comb

1979
Delayed complications in colo-rectal carcinoma treated by combination radiotherapy and 5-fluorouracil--Eastern Cooperative Oncology Group (E.C.O.G.) pilot study.
    International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:3

    Topics: Aged; Colonic Diseases; Colonic Neoplasms; Connective Tissue; Constriction, Pathologic; Female; Fluo

1979
Delayed complications following combination of radiation and chemotherapy.
    International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:3

    Topics: Antineoplastic Agents; Fluorouracil; Humans; Neoplasms; Radiation Injuries; Radiation Tolerance; Res

1979
Management of non-resectable (stage III) breast cancer.
    International journal of radiation oncology, biology, physics, 1979, Volume: 5, Issue:9

    Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Administration Schedule; Drug Therap

1979
[The therapeutic results and early and late toxicities of the treatment of anal canal carcinoma by radiotherapy or chemoradiotherapy].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1991, Volume: 167, Issue:8

    Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Anus Neoplasms; Combine

1991
Chemo-irradiation induced aortoesophageal fistula.
    Journal of surgical oncology, 1991, Volume: 48, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aorta, Thoracic; Aortic Diseases; Cisplatin; Combine

1991
Hyperfractionated radiation and chemotherapy for unresectable localized adenocarcinoma of the pancreas. The Gastrointestinal Tumor Study Group experience.
    Cancer, 1990, Apr-01, Volume: 65, Issue:7

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Thera

1990
Combined modality therapy for locally advanced non-small cell lung carcinoma.
    Cancer, 1990, Dec-01, Volume: 66, Issue:11

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplat

1990
[The effect of local UHF hyperthermia and a fractionated radiation dosage on the incidence of perichondritis during the treatment of laryngeal cancer].
    Meditsinskaia radiologiia, 1990, Volume: 35, Issue:2

    Topics: Adult; Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Humans; Hyperthermia, Induced; In

1990
A study of the late effects of radiotherapy and operation on patients with maxillary cancer. A survey more than 10 years after initial treatment.
    Cancer, 1988, Nov-15, Volume: 62, Issue:10

    Topics: Combined Modality Therapy; Fluorouracil; Humans; Maxillary Neoplasms; Postoperative Complications; R

1988
[Clinical evaluation of FAR therapy (radiotherapy with 5FU and vitamin A) for laryngeal cancer. II. Rates of control and complications].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1985, Sep-25, Volume: 45, Issue:9

    Topics: Combined Modality Therapy; Fluorouracil; Follow-Up Studies; Humans; Laryngeal Neoplasms; Neoplasm Re

1985
[Palliative treatment in patients with lung cancer].
    Nordisk medicin, 1971, Jun-10, Volume: 85, Issue:23

    Topics: Breast Neoplasms; Fluorouracil; Humans; Lung Neoplasms; Methenolone; Palliative Care; Radiation Inju

1971
5-Hydroxyindole-secreting rectal carcinoid tumour.
    Gut, 1972, Volume: 13, Issue:5

    Topics: Adult; Carcinoid Tumor; Duodenal Ulcer; Female; Fluorouracil; Humans; Hydroxyindoleacetic Acid; Live

1972
[The functional state of the liver during conservative treatment of oncologic patients].
    Klinicheskaia meditsina, 1972, Volume: 50, Issue:6

    Topics: Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Esophageal Neoplasms; Fluorouracil; H

1972