Page last updated: 2024-10-27

fluorouracil and Influenza, Human

fluorouracil has been researched along with Influenza, Human in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Influenza, Human: An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia.

Research Excerpts

ExcerptRelevanceReference
"Breast cancer patients on FEC (5-fluorouracil, epirubicin and cyclophosphamide) chemotherapy regimens were vaccinated with influenza virus vaccine."5.24Microarray profile of the humoral immune response to influenza vaccination in breast cancer patients treated with chemotherapy. ( Biesma, DH; de Bruin, E; Koopmans, MP; Meerveld-Eggink, A; Rijkers, GT; Rimmelzwaan, GF; van der Velden, AM; Wumkes, ML, 2017)
"Breast cancer patients received influenza vaccination during FEC (5-fluorouracil, epirubicin and cyclophosphamide)-containing chemotherapy regimens."5.15Response to influenza virus vaccination during chemotherapy in patients with breast cancer. ( Beeker, A; Biesma, DH; de Weerdt, O; Los, M; Meerveld-Eggink, A; Nijziel, MR; Rijkers, GT; Rimmelzwaan, GF; Stouthard, JML; van Beek, R; van der Velden, AMT; van der Velden, AWG; Westerman, M, 2011)
"Anti influenza viral activity was determined by screening against both A and B viral strains."1.36Novel nucleosides as potent influenza viral inhibitors. ( Aryasomayajula, R; Bandi, PR; Jennepalli, S; Kura, RR; Musku, MR; Rondla, SR; Vedula, MS, 2010)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vedula, MS1
Jennepalli, S1
Aryasomayajula, R1
Rondla, SR1
Musku, MR1
Kura, RR1
Bandi, PR1
Wumkes, ML1
van der Velden, AM1
de Bruin, E1
Meerveld-Eggink, A2
Koopmans, MP1
Rimmelzwaan, GF2
Rijkers, GT2
Biesma, DH2
de Weerdt, O1
van der Velden, AMT1
Los, M1
van der Velden, AWG1
Stouthard, JML1
Nijziel, MR1
Westerman, M1
Beeker, A1
van Beek, R1

Trials

2 trials available for fluorouracil and Influenza, Human

ArticleYear
Microarray profile of the humoral immune response to influenza vaccination in breast cancer patients treated with chemotherapy.
    Vaccine, 2017, 03-01, Volume: 35, Issue:9

    Topics: Adult; Aged; Antibodies, Viral; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cy

2017
Response to influenza virus vaccination during chemotherapy in patients with breast cancer.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:9

    Topics: Adult; Aged; Antibodies, Viral; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ch

2011

Other Studies

1 other study available for fluorouracil and Influenza, Human

ArticleYear
Novel nucleosides as potent influenza viral inhibitors.
    Bioorganic & medicinal chemistry, 2010, Sep-01, Volume: 18, Issue:17

    Topics: Animals; Antiviral Agents; Cell Line; Dogs; Humans; Influenza A virus; Influenza B virus; Influenza,

2010