fluorouracil has been researched along with Infectious Myelitis in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Radiation myelitis is a rare but serious complication of radiation therapy." | 1.28 | Radiation myelitis: a complication of concurrent cisplatin and 5-fluorouracil chemotherapy with extended field radiotherapy for carcinoma of the uterine cervix. ( Berman, ML; Bloss, JD; DiSaia, PJ; Hyden, EC; Manetta, A; Mannel, RS; Walker, JL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Smith, FP | 1 |
| Schein, PS | 1 |
| Macdonald, JS | 1 |
| Woolley, PV | 1 |
| Ornitz, R | 1 |
| Rogers, C | 1 |
| Bloss, JD | 1 |
| DiSaia, PJ | 1 |
| Mannel, RS | 1 |
| Hyden, EC | 1 |
| Manetta, A | 1 |
| Walker, JL | 1 |
| Berman, ML | 1 |
| Kagan, AR | 1 |
3 other studies available for fluorouracil and Infectious Myelitis
| Article | Year |
|---|---|
Fast neutron irradiation for locally advanced pancreatic cancer.
Topics: Adenocarcinoma; Colitis; Cost-Benefit Analysis; Energy Transfer; Esophagitis; Evaluation Studies as | 1981 |
Radiation myelitis: a complication of concurrent cisplatin and 5-fluorouracil chemotherapy with extended field radiotherapy for carcinoma of the uterine cervix.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cis | 1991 |
Comments on morbidity in present-day radiotherapy.
Topics: Breast Neoplasms; Buttocks; Carcinoma, Squamous Cell; Dactinomycin; Erythema; Female; Fluorouracil; | 1971 |