fluorouracil has been researched along with Infections, Respiratory Syncytial Virus in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsu, KH | 1 |
| Crowe, JE | 3 |
| Lubeck, MD | 1 |
| Davis, AR | 2 |
| Hung, PP | 1 |
| Chanock, RM | 2 |
| Murphy, BR | 3 |
| Bui, PT | 1 |
| Karron, RA | 1 |
| Wright, PF | 1 |
| Clements-Mann, ML | 1 |
| Thompson, J | 1 |
| Makhene, M | 1 |
| Casey, R | 1 |
1 trial available for fluorouracil and Infections, Respiratory Syncytial Virus
| Article | Year |
|---|---|
Evaluation of two live, cold-passaged, temperature-sensitive respiratory syncytial virus vaccines in chimpanzees and in human adults, infants, and children.
Topics: Adolescent; Adult; Animals; Antibodies, Viral; Cell Line; Child, Preschool; Double-Blind Method; Fem | 1997 |
2 other studies available for fluorouracil and Infections, Respiratory Syncytial Virus
| Article | Year |
|---|---|
Isolation and characterization of a highly attenuated respiratory syncytial virus (RSV) vaccine candidate by mutagenesis of the incompletely attenuated RSV A2 ts-1 NG-1 mutant virus.
Topics: Animals; Azacitidine; Carcinoma, Squamous Cell; Chlorocebus aethiops; Female; Fluorouracil; Male; Mi | 1995 |
A further attenuated derivative of a cold-passaged temperature-sensitive mutant of human respiratory syncytial virus retains immunogenicity and protective efficacy against wild-type challenge in seronegative chimpanzees.
Topics: Animals; Cattle; Cell Line, Transformed; Chlorocebus aethiops; Cold Temperature; Culture Techniques; | 1994 |