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fluorouracil and Infection, Postoperative Wound

fluorouracil has been researched along with Infection, Postoperative Wound in 12 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"The mean follow-up time after treatment for endophthalmitis was 6."2.41Delayed-onset bleb-associated endophthalmitis: clinical features and visual acuity outcomes. ( Budenz, DL; Flynn, HW; Scott, IU; Song, A, 2002)
"Eighty percent of the patients had squamous cell carcinoma and 20% had adenocarcinoma."2.39Concurrent radiation therapy and chemotherapy followed by esophagectomy for localized esophageal carcinoma. ( Bates, BA; Bernard, SA; Detterbeck, FC; Qaqish, BF; Tepper, JE, 1996)
"Postoperative complications were graded according to the Clavien-Dindo classification."1.40Prognostic factors for postoperative morbidity and tumour response after neoadjuvant chemoradiation followed by resection for rectal cancer. ( Berkel, AE; Klaase, JM; van der Palen, J; Woutersen, DP, 2014)
"Of all patients operated for rectal cancer, 27."1.39Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications. ( Fietkau, R; Gock, M; Klar, E; Klautke, G; Prall, F; Rau, B; Schiffmann, L; Wedermann, N, 2013)
" Preoperative chemoradiotherapy consisted of cisplatinum combined chemotherapy and radiotherapy (total dosage of 30-70 Gy)."1.30Analysis of postoperative complications after esophagectomy for esophageal cancer in patients receiving neoadjuvant therapy. ( Eguchi, R; Hayashi, K; Ide, H; Itoh, H; Nakamura, T; Ohta, M; Okamoto, F; Takasaki, K, 1999)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's4 (33.33)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schiffmann, L1
Wedermann, N1
Gock, M1
Prall, F1
Klautke, G1
Fietkau, R1
Rau, B1
Klar, E1
Berkel, AE1
Woutersen, DP1
van der Palen, J1
Klaase, JM1
Beriwal, S1
Shukla, G1
Shinde, A1
Heron, DE1
Kelley, JL1
Edwards, RP1
Sukumvanich, P1
Richards, S1
Olawaiye, AB1
Krivak, TC1
Bates, BA1
Detterbeck, FC1
Bernard, SA1
Qaqish, BF1
Tepper, JE1
Elsaleh, H1
Joseph, D1
Levitt, M1
House, A1
Robbins, P1
Eguchi, R1
Ide, H1
Nakamura, T1
Hayashi, K1
Ohta, M1
Okamoto, F1
Itoh, H1
Takasaki, K1
Song, A1
Scott, IU1
Flynn, HW1
Budenz, DL1
Welch, CE1
Inokuchi, T1
Sano, K1
Kaminogo, M1
Badr el Din, A1
Coibion, M1
Guenier, C1
Nogaret, JM1
Lorent, I1
Van Houtte, P1
Tueni, E1
Mattheiem, W1
Fortner, JG1
Shiu, MH1
Kinne, DW1
Kim, DK1
Castro, EB1
Watson, RC1
Howland, WS1
Beattie, EJ1
Cohn, I1

Reviews

3 reviews available for fluorouracil and Infection, Postoperative Wound

ArticleYear
Concurrent radiation therapy and chemotherapy followed by esophagectomy for localized esophageal carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996, Volume: 14, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carc

1996
Delayed-onset bleb-associated endophthalmitis: clinical features and visual acuity outcomes.
    Ophthalmology, 2002, Volume: 109, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anterior Chamber; Bacteria; Endophthalmitis; Eye Infections, Bacteri

2002
Abdominal surgery (second of three parts).
    The New England journal of medicine, 1975, Oct-30, Volume: 293, Issue:18

    Topics: Abdomen; Acute Disease; Anus Diseases; Appendectomy; Appendicitis; Appendix; Carcinoembryonic Antige

1975

Trials

1 trial available for fluorouracil and Infection, Postoperative Wound

ArticleYear
Complications and toxic manifestations of surgical adjuvant chemotherapy for breast cancer.
    Surgery, gynecology & obstetrics, 1968, Volume: 127, Issue:6

    Topics: Adult; Aged; Blood Cell Count; Blood Platelets; Blood Transfusion; Breast Neoplasms; Clinical Trials

1968

Other Studies

8 other studies available for fluorouracil and Infection, Postoperative Wound

ArticleYear
Intensified neoadjuvant radiochemotherapy for rectal cancer enhances surgical complications.
    BMC surgery, 2013, Sep-30, Volume: 13

    Topics: Adenocarcinoma; Aged; Anastomotic Leak; Antineoplastic Agents; Antineoplastic Combined Chemotherapy

2013
Prognostic factors for postoperative morbidity and tumour response after neoadjuvant chemoradiation followed by resection for rectal cancer.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2014, Volume: 18, Issue:9

    Topics: Adenocarcinoma; Adult; Age Factors; Aged; Aged, 80 and over; Anastomotic Leak; Antimetabolites, Anti

2014
Preoperative intensity modulated radiation therapy and chemotherapy for locally advanced vulvar carcinoma: analysis of pattern of relapse.
    International journal of radiation oncology, biology, physics, 2013, Apr-01, Volume: 85, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous

2013
Pre-operative chemoradiotherapy in locally advanced rectal cancer.
    The Australian and New Zealand journal of surgery, 1999, Volume: 69, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Antimetabolites, Antineoplast

1999
Analysis of postoperative complications after esophagectomy for esophageal cancer in patients receiving neoadjuvant therapy.
    The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi, 1999, Volume: 47, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Esophageal Neoplasms; Esophagectomy; Fluo

1999
Osteoradionecrosis of sphenoid and temporal bones in a patient with maxillary sinus carcinoma: a case report.
    Oral surgery, oral medicine, and oral pathology, 1990, Volume: 70, Issue:3

    Topics: Carcinoma, Squamous Cell; Combined Modality Therapy; Fluorouracil; Humans; Male; Maxillary Sinus Neo

1990
Local postoperative morbidity following pre-operative irradiation in locally advanced breast cancer.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1989, Volume: 15, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cycloph

1989
Major hepatic resection using vascular isolation and hypothermic perfusion.
    Annals of surgery, 1974, Volume: 180, Issue:4

    Topics: Cyclophosphamide; Dactinomycin; Fluorouracil; Hepatectomy; Hepatic Veins; Humans; Hypothermia, Induc

1974