fluorouracil has been researched along with Incontinentia Pigmenti Achromians in 27 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a 47-year-old man who developed a linear serpentine erythematous eruption, overlying the superficial veins on both arms, after treatment with intravenous 5-fluorouracil." | 8.80 | Persistent supravenous erythematous eruption: a rare local complication of intravenous 5-fluorouracil therapy. ( Alomar, A; Lopez-Pousa, A; Pujol, RM; Rocamora, V; Taberner, R, 1998) |
| "Fluorouracil is a common cause of acral erythema and a variety of pigmentary anomalies." | 7.68 | Combination chemotherapy with 5-fluorouracil, folinic acid, and alpha-interferon producing histologic features of graft-versus-host disease. ( Beard, JS; Skelton, HG; Smith, KJ, 1993) |
| "Vitiligo is one of the most challenging dermatological diseases with little improvement promises." | 5.91 | Efficacy and safety of micro-needling combined with topical 5-fluorouracil and excimer light vs. excimer light alone in treatment of non-segmental vitiligo: A comparative study. ( Abdelaleem, HL; Saad, MA; Tawfik, KM, 2023) |
| "We describe a 47-year-old man who developed a linear serpentine erythematous eruption, overlying the superficial veins on both arms, after treatment with intravenous 5-fluorouracil." | 4.80 | Persistent supravenous erythematous eruption: a rare local complication of intravenous 5-fluorouracil therapy. ( Alomar, A; Lopez-Pousa, A; Pujol, RM; Rocamora, V; Taberner, R, 1998) |
| "Fluorouracil is a common cause of acral erythema and a variety of pigmentary anomalies." | 3.68 | Combination chemotherapy with 5-fluorouracil, folinic acid, and alpha-interferon producing histologic features of graft-versus-host disease. ( Beard, JS; Skelton, HG; Smith, KJ, 1993) |
| " Vitamin A acid and benzoyl peroxide have brought significant advances in the topical treatment of acne." | 3.66 | [Advances in topical therapy of skin diseases (author's transl)]. ( Happle, R, 1979) |
| "Vitiligo is one of the most challenging dermatological diseases with little improvement promises." | 1.91 | Efficacy and safety of micro-needling combined with topical 5-fluorouracil and excimer light vs. excimer light alone in treatment of non-segmental vitiligo: A comparative study. ( Abdelaleem, HL; Saad, MA; Tawfik, KM, 2023) |
| "Capecitabine is a prodrug of fluorouracil." | 1.35 | Focal acral hyperpigmentation in a patient undergoing chemotherapy with capecitabine. ( Alonso, V; Calduch, L; Jordá, E; Martín, JM; Pinazo, MI; Villalón, G, 2009) |
| "Capecitabine is an oral prodrug of 5-fluorouracil (5-FU), used in the treatment of metastatic colon and breast cancers; it is also under investigation for use in gastric cancers." | 1.35 | Longitudinal melanonychia induced by capecitabine. ( Hymes, SR; Paravar, T, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (51.85) | 18.7374 |
| 1990's | 7 (25.93) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 3 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Saad, MA | 1 |
| Tawfik, KM | 1 |
| Abdelaleem, HL | 1 |
| Searle, T | 1 |
| Al-Niaimi, F | 1 |
| Ali, FR | 1 |
| Van Belle, E | 1 |
| Manigold, T | 1 |
| Piérache, A | 1 |
| Furber, A | 1 |
| Debry, N | 1 |
| Luycx-Bore, A | 1 |
| Bauchart, JJ | 1 |
| Nugue, O | 1 |
| Huchet, F | 1 |
| Bic, M | 1 |
| Vinchon, F | 1 |
| Sayah, S | 1 |
| Fournier, A | 1 |
| Decoulx, E | 1 |
| Mouhammad, U | 1 |
| Clerc, J | 1 |
| Manchuelle, A | 1 |
| Lazizi, T | 1 |
| Chmait, A | 1 |
| Jeannetteau, J | 1 |
| Hénon, P | 1 |
| Bonin, M | 1 |
| Dupret-Minet, M | 1 |
| Tirouvanziam, A | 1 |
| Molcard, D | 1 |
| Arabucki, F | 1 |
| Py, A | 1 |
| Prunier, F | 1 |
| Delhaye, C | 1 |
| Lemesle, G | 1 |
| Schurtz, G | 1 |
| Cosenza, A | 1 |
| Spillemaeker, H | 1 |
| Verdier, B | 1 |
| Denimal, T | 1 |
| Pamart, T | 1 |
| Sylla, H | 1 |
| Janah, D | 1 |
| Aouate, D | 1 |
| Porouchani, S | 1 |
| Guillez, V | 1 |
| Bonnet, G | 1 |
| Ternacle, J | 1 |
| Labreuche, J | 1 |
| Cayla, G | 1 |
| Vincent, F | 1 |
| Arbache, S | 1 |
| Arbache, ST | 1 |
| Hirata, SH | 1 |
| Ten, LN | 1 |
| Li, W | 1 |
| Kim, MK | 1 |
| Kang, IK | 1 |
| Lee, SY | 1 |
| Jung, HY | 1 |
| Mitsunami, M | 1 |
| Salas-Huetos, A | 1 |
| Mínguez-Alarcón, L | 1 |
| Attaman, JA | 1 |
| Ford, JB | 1 |
| Kathrins, M | 1 |
| Souter, I | 1 |
| Chavarro, JE | 1 |
| Chowdhury, H | 1 |
| Chowdhury, T | 1 |
| Hossain, N | 1 |
| Chowdhury, P | 1 |
| Dos Santos Mascarenhas, J | 1 |
| Bhuiya, MMK | 1 |
| De Anda, MC | 1 |
| Domínguez, JG | 1 |
| Villalón, G | 1 |
| Martín, JM | 1 |
| Pinazo, MI | 1 |
| Calduch, L | 1 |
| Alonso, V | 1 |
| Jordá, E | 1 |
| Paravar, T | 1 |
| Hymes, SR | 1 |
| GOLDMAN, L | 1 |
| BLANEY, DJ | 1 |
| COHEN, W | 1 |
| Nixon, DW | 1 |
| Pirozzi, D | 1 |
| York, RM | 1 |
| Black, M | 1 |
| Lawson, DH | 1 |
| Voelter, WW | 1 |
| Vaughn, CB | 1 |
| Brady, P | 1 |
| Chinn, BJ | 1 |
| Daversa, GC | 1 |
| Parzuchowski, JS | 1 |
| Hrushesky, WJ | 3 |
| Beard, JS | 1 |
| Smith, KJ | 1 |
| Skelton, HG | 1 |
| Babu, KG | 1 |
| Rasheshyam, D | 1 |
| Lalitha, N | 1 |
| Pujol, RM | 1 |
| Rocamora, V | 1 |
| Lopez-Pousa, A | 1 |
| Taberner, R | 1 |
| Alomar, A | 1 |
| Happle, R | 1 |
| Daoud, D | 1 |
| Fox, N | 1 |
| Tan, J | 1 |
| Sahl, WJ | 1 |
| Taira, JW | 1 |
| Vukelja, SJ | 1 |
| Bonner, MW | 1 |
| McCollough, M | 1 |
| Cobb, PW | 1 |
| Gaule, DA | 1 |
| Fanucchi, PJ | 1 |
| Keeling, JH | 1 |
| Perlin, E | 1 |
| Ahlgren, JD | 1 |
| Seminara, P | 1 |
| Franchi, F | 1 |
| Codacci-Pisanelli, G | 1 |
| Aronne, T | 1 |
| Abdolrahim zadeh, S | 1 |
| Cho, KH | 1 |
| Chung, JH | 1 |
| Lee, AY | 1 |
| Lee, YS | 1 |
| Kim, NK | 1 |
| Kim, CW | 1 |
| Baran, R | 1 |
| Laugier, P | 1 |
| Levantine, A | 1 |
| Almeyda, J | 1 |
| Goldmann, L | 1 |
| Igelman, JM | 1 |
| Kitzmiller, K | 1 |
| Piro, AJ | 1 |
| Wilson, RE | 1 |
| Hall, TC | 1 |
| Aliapoulios, MA | 1 |
| Nevinny, HB | 1 |
| Moore, FD | 1 |
4 reviews available for fluorouracil and Incontinentia Pigmenti Achromians
| Article | Year |
|---|---|
5-Fluorouracil in Dermatology: The Diverse Uses Beyond Malignant and Premalignant Skin Disease.
Topics: Adrenal Cortex Hormones; Cicatrix; Combined Modality Therapy; Cosmetic Techniques; Dermatitis; Derma | 2021 |
Persistent supravenous erythematous eruption: a rare local complication of intravenous 5-fluorouracil therapy.
Topics: Antimetabolites, Antineoplastic; Dermis; Drug Eruptions; Erythema; Fluorouracil; Follow-Up Studies; | 1998 |
Unusual serpentine hyperpigmentation associated with 5-fluorouracil. Case report and review of cutaneous manifestations associated with systemic 5-fluorouracil.
Topics: Adenocarcinoma; Aged; Drug Eruptions; Fluorouracil; Humans; Infusions, Intravenous; Male; Photosensi | 1991 |
Drug reactions. XXIV. Cutaneous reactions to cytostatic agents.
Topics: Alopecia; Aminopterin; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Busulfan; Chlor | 1974 |
1 trial available for fluorouracil and Incontinentia Pigmenti Achromians
| Article | Year |
|---|---|
Combination chemotherapy in advanced gastrointestinal malignancy.
Topics: Adenocarcinoma; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Drug Therapy, Combinat | 1980 |
22 other studies available for fluorouracil and Incontinentia Pigmenti Achromians
| Article | Year |
|---|---|
Efficacy and safety of micro-needling combined with topical 5-fluorouracil and excimer light vs. excimer light alone in treatment of non-segmental vitiligo: A comparative study.
Topics: Combined Modality Therapy; Fluorouracil; Humans; Hypopigmentation; Pigmentation Disorders; Treatment | 2023 |
Topics: Adult; Airports; Antifibrotic Agents; Bacterial Typing Techniques; Bacteroidetes; Bangladesh; Bleomy | 2021 |
Melanonychia induced by topical treatment of periungual warts with 5-fluorouracil.
Topics: Administration, Topical; Adult; Antimetabolites; Female; Fluorouracil; Humans; Nail Diseases; Pigmen | 2013 |
Focal acral hyperpigmentation in a patient undergoing chemotherapy with capecitabine.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Capecitabine; Deoxycytidine; Dermoscopy; Female; | 2009 |
Longitudinal melanonychia induced by capecitabine.
Topics: Adult; Antimetabolites, Antineoplastic; Capecitabine; Deoxycytidine; Female; Fluorouracil; Humans; N | 2009 |
ONYCHODYSTROPHY AFTER TOPICAL 5-FLUOROURACIL.
Topics: Fluorouracil; Humans; Nail Diseases; Nails; Pigmentation Disorders; Skin Neoplasms; Toxicology; Wart | 1963 |
Dermatologic changes after systemic cancer therapy.
Topics: Adult; Antineoplastic Agents; Bleomycin; Cyclophosphamide; Cytotoxins; Dactinomycin; Doxorubicin; Dr | 1981 |
Pigmented purpuric dermatosis-like reaction to topical fluorouracil.
Topics: Female; Fluorouracil; Humans; Middle Aged; Pigmentation Disorders | 1983 |
Unusual pigmentary changes associated with 5-fluorouracil therapy.
Topics: Fluorouracil; Humans; Male; Middle Aged; Pigmentation Disorders; Prostatic Neoplasms | 1980 |
Combination chemotherapy with 5-fluorouracil, folinic acid, and alpha-interferon producing histologic features of graft-versus-host disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Eruptions; Erythema; Female; Fluorouracil; Graf | 1993 |
Canities--reversal with chemotherapy.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Colorectal Neoplasm | 1995 |
[Advances in topical therapy of skin diseases (author's transl)].
Topics: Acne Vulgaris; Administration, Topical; Alopecia; Benzoyl Peroxide; Dinitrochlorobenzene; Fluocortol | 1979 |
Alteration in nail pigment after chemotherapy.
Topics: Antineoplastic Agents; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Nails; Pigmentation | 1977 |
Letter: Serpentine supravenous fluorouracil hyperpigmentation.
Topics: Fluorouracil; Humans; Injections, Intravenous; Male; Middle Aged; Pigmentation Disorders; Prostatic | 1976 |
Serpentine supravenous 5-fluorouracil (NSC-19893) hyperpigmentation.
Topics: Fluorouracil; Humans; Male; Middle Aged; Pigmentation Disorders; Prostatic Neoplasms | 1976 |
Erythema ab igne: treatment with 5-fluorouracil cream.
Topics: Administration, Topical; Aged; Erythema; Female; Fluorouracil; Humans; Infrared Rays; Pigmentation D | 1992 |
Pigmentary effects from the protracted infusion of 5-fluorouracil.
Topics: Aged; Female; Fluorouracil; Humans; Pigmentation Disorders; Skin Pigmentation | 1991 |
Discoloration of the nails and early anemia after mitoxantrone, folinic acid and 5-fluorouracil.
Topics: Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Folic Acid; Hemoglobins; Human | 1990 |
Pigmented macules in patients treated with systemic 5-fluorouracil.
Topics: Female; Fluorouracil; Humans; Male; Melanins; Pigmentation Disorders | 1988 |
Melanonychia induced by topical 5-fluorouracil.
Topics: Aged; Female; Fluorouracil; Humans; Nail Diseases; Nails; Pigmentation Disorders | 1985 |
Investigative studies with DMSO in dermatology.
Topics: Animals; Dermatomycoses; Dimethyl Sulfoxide; Drug Eruptions; Fluocinolone Acetonide; Fluorouracil; G | 1967 |
Toxicity studies of fluorouracil used with adrenalectomy in breast cancer.
Topics: Adrenalectomy; Adult; Aged; Alopecia; Ataxia; Blood Platelet Disorders; Breast Neoplasms; Diarrhea; | 1972 |