Page last updated: 2024-10-27

fluorouracil and Ileus

fluorouracil has been researched along with Ileus in 10 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Ileus: A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced.

Research Excerpts

ExcerptRelevanceReference
"We present a case of sigmoid colon cancer with isolated para-aortic lymph node metastasis in a 67-year-old male patient."1.42[A Case of Para-Aortic Lymph Node Metastases of Sigmoid Colon Cancer Treated with Complete Resection]. ( Fukuda, M; Fukunari, H; Hayashi, T; Kato, T; Nakao, K; Okajima, C; Shitara, K; Yamamoto, Y, 2015)
"We report a case of rectal cancer, which was successfully treated with radical resection and neoadjuvant chemoradiotherapy."1.40[Efficiency of pre-operative chemoradiotherapy in treating a case of advanced rectal cancer]. ( Ami, K; Ando, M; Arai, K; Gokita, K; Hayasaka, J; Imai, K; Kitazume, A; Kondou, M; Okamoto, E; Shibayama, T; Takagi, K; Tamura, A; Tei, S; Watanabe, A, 2014)
"Colorectal carcinomas are among the most common tumor types and are generally treated with palliative chemotherapy in case of metastatic disease."1.37Severe toxicity of capecitabine following uncomplicated treatment with 5-fluorouracil/leucovorin. ( Peters, GJ; Schneiders, FL; van den Berg, HP; van der Vliet, HJ; Verheul, HM, 2011)
" After that his general condition recovered, and two cycles of neoadjuvant chemotherapy (NAC) by irinotecan combined with 5-fluorouracil and l-leucovorin (IFL) therapy were performed on an outpatient basis."1.33[A case of advanced rectal carcinoma with multiple lung metastases responding to irinotecan combined with 5-fluorouracil and l-leucovorin (IFL) as neoadjuvant chemotherapy (NAC)]. ( Fukada, T; Hasegawa, A; Hashimoto, R; Hayashi, T; Kametaka, H; Kawano, H; Koyama, T; Seike, K; Tanaka, H; Yasuno, K, 2006)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's8 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mikami, Y1
Tamura, N1
Akiyama, M1
Muraoka, T1
Sakurai, U1
Sawabe, M1
Tamura, A1
Ami, K1
Watanabe, A1
Hayasaka, J1
Takagi, K1
Okamoto, E1
Kitazume, A1
Kondou, M1
Gokita, K1
Imai, K1
Tei, S1
Ando, M1
Arai, K1
Shibayama, T1
Kato, T1
Fukunari, H1
Yamamoto, Y1
Nakao, K1
Okajima, C1
Shitara, K1
Hayashi, T2
Fukuda, M1
Kondo, J1
Maeda, Y1
Nisimura, T1
Nagashima, Y1
Nagashima, A1
Morita, K1
Setoguchi, M1
Sakata, K1
Ishii, Y1
Hirano, Y1
Munechika, T1
Tanaka, K1
Yonemitsu, Y1
Nomi, M1
Shibata, R1
Okamoto, T1
Maeno, H1
Yanagisawa, J1
Kawamoto, S1
Noritomi, T1
Schneiders, FL1
van den Berg, HP1
Peters, GJ1
Verheul, HM1
van der Vliet, HJ1
Hotta, T1
Takifuji, K1
Kobayashi, Y1
Tabuse, K1
Shimada, K1
Maeda, T1
Nakatani, Y1
Fukiage, O1
Yamaue, H1
Takanashi, K1
Katsuki, S1
Fujita, T1
Waga, E1
Shimodate, Y1
Sasaki, K1
Someya, T1
Ohno, K1
Fujita, M1
Mimae, T1
Ninomiya, M1
Sasaki, H1
Kubo, Y1
Kojima, T1
Umeoka, T1
Takakura, N1
Fukada, T1
Yasuno, K1
Koyama, T1
Tanaka, H1
Seike, K1
Kametaka, H1
Hashimoto, R1
Kawano, H1
Hasegawa, A1

Other Studies

10 other studies available for fluorouracil and Ileus

ArticleYear
[A case of pathologically complete response in a patient with locally advanced sigmoid colon cancer after chemotherapy including bevacizumab/FOLFOX4].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:6

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab

2014
[Efficiency of pre-operative chemoradiotherapy in treating a case of advanced rectal cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2014, Volume: 41, Issue:12

    Topics: Adenocarcinoma; Aged, 80 and over; Antimetabolites, Antineoplastic; Capecitabine; Chemoradiotherapy;

2014
[A Case of Para-Aortic Lymph Node Metastases of Sigmoid Colon Cancer Treated with Complete Resection].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2015, Volume: 42, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aorta; Capecitabine; Deoxycytidine; Fluorourac

2015
[A Case of Small Bowel Adenocarcinoma That Was Diagnosed and Treated using Laparoscopic Surgery].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:12

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, A

2016
[A Case of Locally Far-Advanced Colon Cancer Resected by Laparoscopic Surgery after Colonic Stent Insertion and Neoadjuvant Chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2016, Volume: 43, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Fluorouracil; Hum

2016
Severe toxicity of capecitabine following uncomplicated treatment with 5-fluorouracil/leucovorin.
    Medical oncology (Northwood, London, England), 2011, Volume: 28, Issue:4

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Ato

2011
Management of obstructive colorectal cancer: evaluation of preoperative bowel decompression using ileus tube drainage.
    Surgery today, 2012, Volume: 42, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colectomy; Colorectal

2012
[A case of advanced primary colorectal carcinoma accompanied by liver metastasis in which ileus developed due to marked fibrosis with cicatricial formation in primary colorectal cancer treated by chemotherapy including bevacizumab].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2012, Volume: 109, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carc

2012
[A case of recurrent gastric cancer with improvement of obstructive symptoms caused by carcinomatous peritonitis and prolonged survival by chemotherapy with combined use of Paclitaxel and 5-FU].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:2

    Topics: Adenocarcinoma, Scirrhous; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality

2006
[A case of advanced rectal carcinoma with multiple lung metastases responding to irinotecan combined with 5-fluorouracil and l-leucovorin (IFL) as neoadjuvant chemotherapy (NAC)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Chemotherapy, Adjuvant

2006