fluorouracil has been researched along with Hypomenorrhea in 3 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of breast cancer by combination therapy induced luteal insufficiency, anovulatory cycles and sometimes hypergonadotropic amenorrhea in premenopausal women with previously normal mentrual cycles and ovarian function." | 1.26 | The effect of combination chemotherapy on ovarian, hypothalamic and pituitary function in patients with breast cancer. ( Geiger, W; Künzig, HJ; Schmidt-Rhode, P; Schulz, KD; Weymar, P, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCune, JS | 1 |
| Games, DM | 1 |
| Espirito, JL | 1 |
| Schulz, KD | 1 |
| Schmidt-Rhode, P | 1 |
| Weymar, P | 1 |
| Künzig, HJ | 1 |
| Geiger, W | 1 |
| Weed, JC | 1 |
3 other studies available for fluorouracil and Hypomenorrhea
| Article | Year |
|---|---|
Assessment of ovarian failure and osteoporosis in premenopausal breast cancer survivors.
Topics: Absorptiometry, Photon; Administration, Oral; Adult; Age Factors; Antineoplastic Combined Chemothera | 2005 |
The effect of combination chemotherapy on ovarian, hypothalamic and pituitary function in patients with breast cancer.
Topics: Adult; Amenorrhea; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; F | 1979 |
Office gynecology.
Topics: Adult; Alcohols; Behcet Syndrome; Candidiasis, Vulvovaginal; Colposcopy; Condylomata Acuminata; Cryo | 1972 |