Page last updated: 2024-10-27

fluorouracil and Hypomenorrhea

fluorouracil has been researched along with Hypomenorrhea in 3 studies

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.

Research Excerpts

ExcerptRelevanceReference
"Treatment of breast cancer by combination therapy induced luteal insufficiency, anovulatory cycles and sometimes hypergonadotropic amenorrhea in premenopausal women with previously normal mentrual cycles and ovarian function."1.26The effect of combination chemotherapy on ovarian, hypothalamic and pituitary function in patients with breast cancer. ( Geiger, W; Künzig, HJ; Schmidt-Rhode, P; Schulz, KD; Weymar, P, 1979)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McCune, JS1
Games, DM1
Espirito, JL1
Schulz, KD1
Schmidt-Rhode, P1
Weymar, P1
Künzig, HJ1
Geiger, W1
Weed, JC1

Other Studies

3 other studies available for fluorouracil and Hypomenorrhea

ArticleYear
Assessment of ovarian failure and osteoporosis in premenopausal breast cancer survivors.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2005, Volume: 11, Issue:2

    Topics: Absorptiometry, Photon; Administration, Oral; Adult; Age Factors; Antineoplastic Combined Chemothera

2005
The effect of combination chemotherapy on ovarian, hypothalamic and pituitary function in patients with breast cancer.
    Archives of gynecology, 1979, Volume: 227, Issue:4

    Topics: Adult; Amenorrhea; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Female; F

1979
Office gynecology.
    Postgraduate medicine, 1972, Volume: 52, Issue:4

    Topics: Adult; Alcohols; Behcet Syndrome; Candidiasis, Vulvovaginal; Colposcopy; Condylomata Acuminata; Cryo

1972