fluorouracil has been researched along with Hypesthesia in 1 studies
Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
5-fluorouracil : A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth.
Hypesthesia: Absent or reduced sensitivity to cutaneous stimulation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These results reveal that distal hypesthesia occurring under treatment with oxaliplatin is markedly pronounced in the fingertips; however, as thermal threshold is unknown before treatment, it is difficult to assert that fingertip thermal hypesthesia has developed under treatment." | 1.46 | Quantification of Chronic Oxaliplatin-Induced Hypesthesia in Two Areas of the Hand. ( Andriamamonjy, M; Beaussier, H; Coudoré, F; Delmotte, JB; Savinelli, F, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andriamamonjy, M | 1 |
| Delmotte, JB | 1 |
| Savinelli, F | 1 |
| Beaussier, H | 1 |
| Coudoré, F | 1 |
1 other study available for fluorouracil and Hypesthesia
| Article | Year |
|---|---|
Quantification of Chronic Oxaliplatin-Induced Hypesthesia in Two Areas of the Hand.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Electrodiagnosis; Femal | 2017 |